Q9D415 (DLGP1_MOUSE) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Disks large-associated protein 1
Short name=DAP-1

Alternative name(s):
Guanylate kinase-associated protein
PSD-95/SAP90-binding protein 1
SAP90/PSD-95-associated protein 1
Short name=SAPAP1

Gene names

Name:	Dlgap1
Synonyms:	Kiaa4162

Organism

Mus musculus (Mouse) [Reference proteome]

Taxonomic identifier

10090 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Euarchontoglires › Glires › Rodentia › Sciurognathi › Muroidea › Muridae › Murinae › Mus › Mus

Protein attributes

Sequence length	992 AA.
Sequence status	Complete.
Protein existence	Evidence at protein level

General annotation (Comments)

Function	Part of the postsynaptic scaffold in neuronal cells.
Subunit structure	Interacts with the guanylate kinase-like domain of DLG1, DLG2, DLG3, DLG4 and AIP1. Interacts with the PDZ domain of SHANK1, SHANK2 and SHANK3. Found in a complex with DLG4 and SHANK1, SHANK2 or SHANK3. Found in a complex with DLG4 and BEGAIN. Interacts with DYL2 and LRFN1 By similarity.
Subcellular location	Cell membrane; Peripheral membrane protein By similarity. Cell junction › synapse › postsynaptic cell membrane › postsynaptic density By similarity. Cell junction › synapse By similarity. Note: Found in postsynaptic density of neuronal cells By similarity.
Tissue specificity	Highest levels in the neocortex, part of the hippocampus, the granule cell layer of the cerebellum, the glomerular layer of the olfactory bulb, the inner plexiform layer of the retina, the ventral and dorsal horn of the spinal chord, the neuromuscular junction and the submandibular ganglion. Ref.1
Sequence similarities	Belongs to the SAPAP family.
Sequence caution	The sequence BAD90519.1 differs from that shown. Reason: Erroneous initiation.

Ontologies

Keywords
Cellular component	Cell junction Cell membrane Membrane Postsynaptic cell membrane Synapse
Coding sequence diversity	Alternative splicing
PTM	Phosphoprotein
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	synaptic transmission Traceable author statement PubMed 9882498. Source: MGI
Cellular_component	cell junction Inferred from electronic annotation. Source: UniProtKB-KW plasma membrane Inferred from electronic annotation. Source: UniProtKB-SubCell postsynaptic density Inferred from direct assay PubMed 21558424. Source: BHF-UCL postsynaptic membrane Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Alternative products

This entry describes 6 isoforms produced by alternative splicing. [Align] [Select]

Isoform 1 (identifier: Q9D415-1)

Also known as: SAPAP1;

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

Isoform 2 (identifier: Q9D415-2)

The sequence of this isoform differs from the canonical sequence as follows:
     537-546: Missing.

Note: No experimental confirmation available.

Isoform 3 (identifier: Q9D415-3)

Also known as: GKAP1a;

The sequence of this isoform differs from the canonical sequence as follows:
     547-574: Missing.

Isoform 4 (identifier: Q9D415-4)

Also known as: GKAP1b;

The sequence of this isoform differs from the canonical sequence as follows:
     537-546: Missing.
     924-944: ERRAPPPVPKKPAKGPAPLIR → VEQCRFCMVHLKPCTNAGQSK
     945-992: Missing.

Isoform 5 (identifier: Q9D415-5)

The sequence of this isoform differs from the canonical sequence as follows:
     538-538: V → E
     539-992: Missing.

Note: No experimental confirmation available.

Isoform 6 (identifier: Q9D415-6)

The sequence of this isoform differs from the canonical sequence as follows:
     398-992: Missing.

Note: No experimental confirmation available.

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 992	992	Disks large-associated protein 1		PRO_0000174289
Regions
	Region	665 – 676	12	Interaction with DYL2 By similarity
	Region	687 – 698	12	Interaction with DYL2 By similarity
	Motif	990 – 992	3	PDZ-binding By similarity
Amino acid modifications
	Modified residue	123	1	Phosphotyrosine Ref.6
	Modified residue	134	1	Phosphoserine Ref.5
	Modified residue	352	1	Phosphoserine Ref.5
	Modified residue	362	1	Phosphoserine Ref.5
	Modified residue	389	1	Phosphoserine Ref.7
	Modified residue	412	1	Phosphoserine Ref.5
	Modified residue	421	1	Phosphoserine Ref.7
	Modified residue	436	1	Phosphothreonine Ref.7
	Modified residue	437	1	Phosphoserine Ref.5
	Modified residue	446	1	Phosphoserine Ref.5
	Modified residue	499	1	Phosphoserine Ref.5
	Modified residue	509	1	Phosphoserine Ref.5 Ref.7
	Modified residue	516	1	Phosphoserine Ref.5 Ref.7
	Modified residue	947	1	Phosphoserine Ref.5
Natural variations
	Alternative sequence	398 – 992	595	Missing in isoform 6.		VSP_015408
	Alternative sequence	537 – 546	10	Missing in isoform 2 and isoform 4.		VSP_015409
	Alternative sequence	538	1	V → E in isoform 5.		VSP_015410
	Alternative sequence	539 – 992	454	Missing in isoform 5.		VSP_015411
	Alternative sequence	547 – 574	28	Missing in isoform 3.		VSP_015412
	Alternative sequence	924 – 944	21	ERRAP…APLIR → VEQCRFCMVHLKPCTNAGQS K in isoform 4.		VSP_015413
	Alternative sequence	945 – 992	48	Missing in isoform 4.		VSP_015414
Experimental info
	Sequence conflict	383	1	L → P in BAD90519. Ref.3
	Sequence conflict	397	1	K → R in AAP70755. Ref.1
	Sequence conflict	431	1	P → H in BAC27391. Ref.2
	Sequence conflict	752	1	S → F in BAC28619. Ref.2

Sequences

	Sequence		Length	Mass (Da)
	Isoform 1 (SAPAP1) [UniParc]. Last modified July 19, 2005. Version 3. Checksum: 9962C8B56A33EE13	FASTA	992	110,374
	10 20 30 40 50 60 MKGLSGSRSH HHGITCEAAC DSLSHHSDHK PYLLSPVDHH PADHPYYTQR NSFQAECVGP 70 80 90 100 110 120 FSDPLASSTF PRRHYTSQQE LKDESALVPR TLATKANRLP TNLLDQFERQ LPLSRDGYHT 130 140 150 160 170 180 LQYKRTAVEH RSDSPGRIRH LVHSVQKLFT KSHSLEGPSK GSVNGGKASP DESQTLRYGK 190 200 210 220 230 240 RSKSKERRSE SKARSNASNA SPTSPSWWSS DDNLDGDMCL YHTPSGVMTM GRCPDRSASQ 250 260 270 280 290 300 YFMEAYNTIS EQAVKASRSN NDIKCSTCAN LPVTLDAPLL KKSAWSSTLT VSRAREVYQK 310 320 330 340 350 360 ASVNMDQAMV KSEACQQERS CQYLQVPQDE WSGYTPRGKD DEIPCRRMRS GSYIKAMGDE 370 380 390 400 410 420 DSGDSDTSPK PSPKVAARRE SYLKATQPSL TELTTLKISN EHSPKLQIRS HSYLRAVSEV 430 440 450 460 470 480 SINRSLDSLD PAGLLTSPKF RSRNESYMRA MSTISQVSEM EVNGQFESVC ESVFSELESQ 490 500 510 520 530 540 AVEALDLPLP GCFRMRSHSY VRAIEKGCSQ DDECVSLRSS SPPRTTTTVR TIQSSTGVIK 550 560 570 580 590 600 LSSAVEVSSC ITTYKKTPPP VPPRTTTKPF ISITAQSSTE SAQDAYMDGQ GQRGDMISQS 610 620 630 640 650 660 GLSNSTESLD SMKALTAAIE AANAQIHGPA SQHMGSNAAA VTTTTTIATV TTEDRKKDFK 670 680 690 700 710 720 KNRCLSIGIQ VDDAEEPEKM AESKTSNKFQ SVGVQVEEEK CFRRFTRSNS VTTAVQADLD 730 740 750 760 770 780 FHDNLENSLE SIEDNSCPGP MARQFSRDAS TSTVSIQGSG NHYHACAADD DFDTDFDPSI 790 800 810 820 830 840 LPPPDPWIDS ITEDPLEAVQ RSVCHRDGHW FLKLLQAERD RMEGWCKLME REERENNLPE 850 860 870 880 890 900 DILGKIRTAV GSAQLLMAQK FYQFRELCEE NLNPNAHPRP TSQDLAGFWD MLQLSIENIS 910 920 930 940 950 960 MKFDELHQLK ANNWKQMDPL DKKERRAPPP VPKKPAKGPA PLIRERSLES SQRQEARKRL 970 980 990 MAAKRAASVR QNSATESAES IEIYIPEAQT RL
	Isoform 2 [UniParc]. Checksum: 9518AAB72BB13EE9	FASTA	982	109,390
	10 20 30 40 50 60 MKGLSGSRSH HHGITCEAAC DSLSHHSDHK PYLLSPVDHH PADHPYYTQR NSFQAECVGP 70 80 90 100 110 120 FSDPLASSTF PRRHYTSQQE LKDESALVPR TLATKANRLP TNLLDQFERQ LPLSRDGYHT 130 140 150 160 170 180 LQYKRTAVEH RSDSPGRIRH LVHSVQKLFT KSHSLEGPSK GSVNGGKASP DESQTLRYGK 190 200 210 220 230 240 RSKSKERRSE SKARSNASNA SPTSPSWWSS DDNLDGDMCL YHTPSGVMTM GRCPDRSASQ 250 260 270 280 290 300 YFMEAYNTIS EQAVKASRSN NDIKCSTCAN LPVTLDAPLL KKSAWSSTLT VSRAREVYQK 310 320 330 340 350 360 ASVNMDQAMV KSEACQQERS CQYLQVPQDE WSGYTPRGKD DEIPCRRMRS GSYIKAMGDE 370 380 390 400 410 420 DSGDSDTSPK PSPKVAARRE SYLKATQPSL TELTTLKISN EHSPKLQIRS HSYLRAVSEV 430 440 450 460 470 480 SINRSLDSLD PAGLLTSPKF RSRNESYMRA MSTISQVSEM EVNGQFESVC ESVFSELESQ 490 500 510 520 530 540 AVEALDLPLP GCFRMRSHSY VRAIEKGCSQ DDECVSLRSS SPPRTTTTVR TIQSSTVSSC 550 560 570 580 590 600 ITTYKKTPPP VPPRTTTKPF ISITAQSSTE SAQDAYMDGQ GQRGDMISQS GLSNSTESLD 610 620 630 640 650 660 SMKALTAAIE AANAQIHGPA SQHMGSNAAA VTTTTTIATV TTEDRKKDFK KNRCLSIGIQ 670 680 690 700 710 720 VDDAEEPEKM AESKTSNKFQ SVGVQVEEEK CFRRFTRSNS VTTAVQADLD FHDNLENSLE 730 740 750 760 770 780 SIEDNSCPGP MARQFSRDAS TSTVSIQGSG NHYHACAADD DFDTDFDPSI LPPPDPWIDS 790 800 810 820 830 840 ITEDPLEAVQ RSVCHRDGHW FLKLLQAERD RMEGWCKLME REERENNLPE DILGKIRTAV 850 860 870 880 890 900 GSAQLLMAQK FYQFRELCEE NLNPNAHPRP TSQDLAGFWD MLQLSIENIS MKFDELHQLK 910 920 930 940 950 960 ANNWKQMDPL DKKERRAPPP VPKKPAKGPA PLIRERSLES SQRQEARKRL MAAKRAASVR 970 980 QNSATESAES IEIYIPEAQT RL
	Isoform 3 (GKAP1a) [UniParc]. Checksum: B45BBAFF2C4E8740	FASTA	964	107,331
	10 20 30 40 50 60 MKGLSGSRSH HHGITCEAAC DSLSHHSDHK PYLLSPVDHH PADHPYYTQR NSFQAECVGP 70 80 90 100 110 120 FSDPLASSTF PRRHYTSQQE LKDESALVPR TLATKANRLP TNLLDQFERQ LPLSRDGYHT 130 140 150 160 170 180 LQYKRTAVEH RSDSPGRIRH LVHSVQKLFT KSHSLEGPSK GSVNGGKASP DESQTLRYGK 190 200 210 220 230 240 RSKSKERRSE SKARSNASNA SPTSPSWWSS DDNLDGDMCL YHTPSGVMTM GRCPDRSASQ 250 260 270 280 290 300 YFMEAYNTIS EQAVKASRSN NDIKCSTCAN LPVTLDAPLL KKSAWSSTLT VSRAREVYQK 310 320 330 340 350 360 ASVNMDQAMV KSEACQQERS CQYLQVPQDE WSGYTPRGKD DEIPCRRMRS GSYIKAMGDE 370 380 390 400 410 420 DSGDSDTSPK PSPKVAARRE SYLKATQPSL TELTTLKISN EHSPKLQIRS HSYLRAVSEV 430 440 450 460 470 480 SINRSLDSLD PAGLLTSPKF RSRNESYMRA MSTISQVSEM EVNGQFESVC ESVFSELESQ 490 500 510 520 530 540 AVEALDLPLP GCFRMRSHSY VRAIEKGCSQ DDECVSLRSS SPPRTTTTVR TIQSSTGVIK 550 560 570 580 590 600 LSSAVEAQSS TESAQDAYMD GQGQRGDMIS QSGLSNSTES LDSMKALTAA IEAANAQIHG 610 620 630 640 650 660 PASQHMGSNA AAVTTTTTIA TVTTEDRKKD FKKNRCLSIG IQVDDAEEPE KMAESKTSNK 670 680 690 700 710 720 FQSVGVQVEE EKCFRRFTRS NSVTTAVQAD LDFHDNLENS LESIEDNSCP GPMARQFSRD 730 740 750 760 770 780 ASTSTVSIQG SGNHYHACAA DDDFDTDFDP SILPPPDPWI DSITEDPLEA VQRSVCHRDG 790 800 810 820 830 840 HWFLKLLQAE RDRMEGWCKL MEREERENNL PEDILGKIRT AVGSAQLLMA QKFYQFRELC 850 860 870 880 890 900 EENLNPNAHP RPTSQDLAGF WDMLQLSIEN ISMKFDELHQ LKANNWKQMD PLDKKERRAP 910 920 930 940 950 960 PPVPKKPAKG PAPLIRERSL ESSQRQEARK RLMAAKRAAS VRQNSATESA ESIEIYIPEA QTRL
	Isoform 4 (GKAP1b) [UniParc]. Checksum: 224A365837BCE785	FASTA	934	104,064
	10 20 30 40 50 60 MKGLSGSRSH HHGITCEAAC DSLSHHSDHK PYLLSPVDHH PADHPYYTQR NSFQAECVGP 70 80 90 100 110 120 FSDPLASSTF PRRHYTSQQE LKDESALVPR TLATKANRLP TNLLDQFERQ LPLSRDGYHT 130 140 150 160 170 180 LQYKRTAVEH RSDSPGRIRH LVHSVQKLFT KSHSLEGPSK GSVNGGKASP DESQTLRYGK 190 200 210 220 230 240 RSKSKERRSE SKARSNASNA SPTSPSWWSS DDNLDGDMCL YHTPSGVMTM GRCPDRSASQ 250 260 270 280 290 300 YFMEAYNTIS EQAVKASRSN NDIKCSTCAN LPVTLDAPLL KKSAWSSTLT VSRAREVYQK 310 320 330 340 350 360 ASVNMDQAMV KSEACQQERS CQYLQVPQDE WSGYTPRGKD DEIPCRRMRS GSYIKAMGDE 370 380 390 400 410 420 DSGDSDTSPK PSPKVAARRE SYLKATQPSL TELTTLKISN EHSPKLQIRS HSYLRAVSEV 430 440 450 460 470 480 SINRSLDSLD PAGLLTSPKF RSRNESYMRA MSTISQVSEM EVNGQFESVC ESVFSELESQ 490 500 510 520 530 540 AVEALDLPLP GCFRMRSHSY VRAIEKGCSQ DDECVSLRSS SPPRTTTTVR TIQSSTVSSC 550 560 570 580 590 600 ITTYKKTPPP VPPRTTTKPF ISITAQSSTE SAQDAYMDGQ GQRGDMISQS GLSNSTESLD 610 620 630 640 650 660 SMKALTAAIE AANAQIHGPA SQHMGSNAAA VTTTTTIATV TTEDRKKDFK KNRCLSIGIQ 670 680 690 700 710 720 VDDAEEPEKM AESKTSNKFQ SVGVQVEEEK CFRRFTRSNS VTTAVQADLD FHDNLENSLE 730 740 750 760 770 780 SIEDNSCPGP MARQFSRDAS TSTVSIQGSG NHYHACAADD DFDTDFDPSI LPPPDPWIDS 790 800 810 820 830 840 ITEDPLEAVQ RSVCHRDGHW FLKLLQAERD RMEGWCKLME REERENNLPE DILGKIRTAV 850 860 870 880 890 900 GSAQLLMAQK FYQFRELCEE NLNPNAHPRP TSQDLAGFWD MLQLSIENIS MKFDELHQLK 910 920 930 ANNWKQMDPL DKKVEQCRFC MVHLKPCTNA GQSK
	Isoform 5 [UniParc]. Checksum: A562146ADAE2C929	FASTA	538	59,879
	10 20 30 40 50 60 MKGLSGSRSH HHGITCEAAC DSLSHHSDHK PYLLSPVDHH PADHPYYTQR NSFQAECVGP 70 80 90 100 110 120 FSDPLASSTF PRRHYTSQQE LKDESALVPR TLATKANRLP TNLLDQFERQ LPLSRDGYHT 130 140 150 160 170 180 LQYKRTAVEH RSDSPGRIRH LVHSVQKLFT KSHSLEGPSK GSVNGGKASP DESQTLRYGK 190 200 210 220 230 240 RSKSKERRSE SKARSNASNA SPTSPSWWSS DDNLDGDMCL YHTPSGVMTM GRCPDRSASQ 250 260 270 280 290 300 YFMEAYNTIS EQAVKASRSN NDIKCSTCAN LPVTLDAPLL KKSAWSSTLT VSRAREVYQK 310 320 330 340 350 360 ASVNMDQAMV KSEACQQERS CQYLQVPQDE WSGYTPRGKD DEIPCRRMRS GSYIKAMGDE 370 380 390 400 410 420 DSGDSDTSPK PSPKVAARRE SYLKATQPSL TELTTLKISN EHSPKLQIRS HSYLRAVSEV 430 440 450 460 470 480 SINRSLDSLD PAGLLTSPKF RSRNESYMRA MSTISQVSEM EVNGQFESVC ESVFSELESQ 490 500 510 520 530 AVEALDLPLP GCFRMRSHSY VRAIEKGCSQ DDECVSLRSS SPPRTTTTVR TIQSSTGE
	Isoform 6 [UniParc]. Checksum: 63EB6CC30E996F60	FASTA	397	44,247
	10 20 30 40 50 60 MKGLSGSRSH HHGITCEAAC DSLSHHSDHK PYLLSPVDHH PADHPYYTQR NSFQAECVGP 70 80 90 100 110 120 FSDPLASSTF PRRHYTSQQE LKDESALVPR TLATKANRLP TNLLDQFERQ LPLSRDGYHT 130 140 150 160 170 180 LQYKRTAVEH RSDSPGRIRH LVHSVQKLFT KSHSLEGPSK GSVNGGKASP DESQTLRYGK 190 200 210 220 230 240 RSKSKERRSE SKARSNASNA SPTSPSWWSS DDNLDGDMCL YHTPSGVMTM GRCPDRSASQ 250 260 270 280 290 300 YFMEAYNTIS EQAVKASRSN NDIKCSTCAN LPVTLDAPLL KKSAWSSTLT VSRAREVYQK 310 320 330 340 350 360 ASVNMDQAMV KSEACQQERS CQYLQVPQDE WSGYTPRGKD DEIPCRRMRS GSYIKAMGDE 370 380 390 DSGDSDTSPK PSPKVAARRE SYLKATQPSL TELTTLK

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Differential mRNA expression and protein localization of the SAP90/PSD-95-associated proteins (SAPAPs) in the nervous system of the mouse." Welch J.M., Wang D., Feng G. J. Comp. Neurol. 472:24-39(2004) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 3), TISSUE SPECIFICITY. Strain: ICR.
[2]	"The transcriptional landscape of the mammalian genome." Carninci P., Kasukawa T., Katayama S., Gough J., Frith M.C., Maeda N., Oyama R., Ravasi T., Lenhard B., Wells C., Kodzius R., Shimokawa K., Bajic V.B., Brenner S.E., Batalov S., Forrest A.R., Zavolan M., Davis M.J. , Wilming L.G., Aidinis V., Allen J.E., Ambesi-Impiombato A., Apweiler R., Aturaliya R.N., Bailey T.L., Bansal M., Baxter L., Beisel K.W., Bersano T., Bono H., Chalk A.M., Chiu K.P., Choudhary V., Christoffels A., Clutterbuck D.R., Crowe M.L., Dalla E., Dalrymple B.P., de Bono B., Della Gatta G., di Bernardo D., Down T., Engstrom P., Fagiolini M., Faulkner G., Fletcher C.F., Fukushima T., Furuno M., Futaki S., Gariboldi M., Georgii-Hemming P., Gingeras T.R., Gojobori T., Green R.E., Gustincich S., Harbers M., Hayashi Y., Hensch T.K., Hirokawa N., Hill D., Huminiecki L., Iacono M., Ikeo K., Iwama A., Ishikawa T., Jakt M., Kanapin A., Katoh M., Kawasawa Y., Kelso J., Kitamura H., Kitano H., Kollias G., Krishnan S.P., Kruger A., Kummerfeld S.K., Kurochkin I.V., Lareau L.F., Lazarevic D., Lipovich L., Liu J., Liuni S., McWilliam S., Madan Babu M., Madera M., Marchionni L., Matsuda H., Matsuzawa S., Miki H., Mignone F., Miyake S., Morris K., Mottagui-Tabar S., Mulder N., Nakano N., Nakauchi H., Ng P., Nilsson R., Nishiguchi S., Nishikawa S., Nori F., Ohara O., Okazaki Y., Orlando V., Pang K.C., Pavan W.J., Pavesi G., Pesole G., Petrovsky N., Piazza S., Reed J., Reid J.F., Ring B.Z., Ringwald M., Rost B., Ruan Y., Salzberg S.L., Sandelin A., Schneider C., Schoenbach C., Sekiguchi K., Semple C.A., Seno S., Sessa L., Sheng Y., Shibata Y., Shimada H., Shimada K., Silva D., Sinclair B., Sperling S., Stupka E., Sugiura K., Sultana R., Takenaka Y., Taki K., Tammoja K., Tan S.L., Tang S., Taylor M.S., Tegner J., Teichmann S.A., Ueda H.R., van Nimwegen E., Verardo R., Wei C.L., Yagi K., Yamanishi H., Zabarovsky E., Zhu S., Zimmer A., Hide W., Bult C., Grimmond S.M., Teasdale R.D., Liu E.T., Brusic V., Quackenbush J., Wahlestedt C., Mattick J.S., Hume D.A., Kai C., Sasaki D., Tomaru Y., Fukuda S., Kanamori-Katayama M., Suzuki M., Aoki J., Arakawa T., Iida J., Imamura K., Itoh M., Kato T., Kawaji H., Kawagashira N., Kawashima T., Kojima M., Kondo S., Konno H., Nakano K., Ninomiya N., Nishio T., Okada M., Plessy C., Shibata K., Shiraki T., Suzuki S., Tagami M., Waki K., Watahiki A., Okamura-Oho Y., Suzuki H., Kawai J., Hayashizaki Y. Science 309:1559-1563(2005) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 5 AND 6), NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 660-992 (ISOFORM 4). Strain: C57BL/6J. Tissue: Diencephalon and Testis.
[3]	"Prediction of the coding sequences of mouse homologues of KIAA gene. The complete nucleotide sequences of mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries." Okazaki N., Kikuno R.F., Ohara R., Inamoto S., Nagase T., Ohara O., Koga H. Submitted (FEB-2005) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2). Tissue: Fetal brain.
[4]	"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)." The MGC Project Team Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1), NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 210-992 (ISOFORM 4). Strain: C57BL/6. Tissue: Brain.
[5]	"Comprehensive identification of phosphorylation sites in postsynaptic density preparations." Trinidad J.C., Specht C.G., Thalhammer A., Schoepfer R., Burlingame A.L. Mol. Cell. Proteomics 5:914-922(2006) [PubMed] [Europe PMC] [Abstract] Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-134; SER-352; SER-362; SER-412; SER-437; SER-446; SER-499; SER-509; SER-516 AND SER-947, MASS SPECTROMETRY. Tissue: Brain.
[6]	"Large-scale identification and evolution indexing of tyrosine phosphorylation sites from murine brain." Ballif B.A., Carey G.R., Sunyaev S.R., Gygi S.P. J. Proteome Res. 7:311-318(2008) [PubMed] [Europe PMC] [Abstract] Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT TYR-123, MASS SPECTROMETRY. Tissue: Brain.
[7]	"Qualitative and quantitative analyses of protein phosphorylation in naive and stimulated mouse synaptosomal preparations." Munton R.P., Tweedie-Cullen R., Livingstone-Zatchej M., Weinandy F., Waidelich M., Longo D., Gehrig P., Potthast F., Rutishauser D., Gerrits B., Panse C., Schlapbach R., Mansuy I.M. Mol. Cell. Proteomics 6:283-293(2007) [PubMed] [Europe PMC] [Abstract] Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-389; SER-421; THR-436; SER-509 AND SER-516, MASS SPECTROMETRY. Tissue: Brain cortex.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AY243846 mRNA. Translation: AAP70755.2. AK031410 mRNA. Translation: BAC27391.1. AK033901 mRNA. Translation: BAC28508.1. AK034182 mRNA. Translation: BAC28619.1. AK220515 mRNA. Translation: BAD90519.1. Different initiation. BC062120 mRNA. Translation: AAH62120.1. BC094369 mRNA. Translation: AAH94369.1.
IPI	IPI00136402. IPI00473783. IPI00648461. IPI00648858. IPI00649710. IPI00650032.
RefSeq	NP_081988.3. NM_027712.3. NP_808307.2. NM_177639.6.
UniGene	Mm.311840. Mm.367369.
3D structure databases
ProteinModelPortal	Q9D415.
ModBase	Search...
Protein-protein interaction databases
IntAct	Q9D415. 3 interactions.
MINT	MINT-136157.
PTM databases
PhosphoSite	Q9D415.
Proteomic databases
PaxDb	Q9D415.
PRIDE	Q9D415.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
Ensembl	ENSMUST00000060072; ENSMUSP00000052858; ENSMUSG00000003279. ENSMUST00000133983; ENSMUSP00000116716; ENSMUSG00000003279. ENSMUST00000135938; ENSMUSP00000118497; ENSMUSG00000003279. ENSMUST00000155016; ENSMUSP00000122896; ENSMUSG00000003279.
GeneID	224997.
KEGG	mmu:224997.
UCSC	uc008dky.1. mouse. uc008dla.1. mouse. uc008dle.2. mouse. uc008dlf.2. mouse.
Organism-specific databases
CTD	9229.
MGI	MGI:1346065. Dlgap1.
Rouge	Search...
Phylogenomic databases
eggNOG	NOG277836.
GeneTree	ENSGT00550000074473.
HOVERGEN	HBG018957.
InParanoid	Q9D415.
KO	K15008.
OMA	PDETQTV.
Gene expression databases
ArrayExpress	Q9D415.
Bgee	Q9D415.
Genevestigator	Q9D415.
GermOnline	ENSMUSG00000003279. Mus musculus.
Family and domain databases
InterPro	IPR005026. GKAP. [Graphical view]
Pfam	PF03359. GKAP. 1 hit. [Graphical view]
ProtoNet	Search...
Other
NextBio	377488.
SOURCE	Search...

Entry information

Entry name

DLGP1_MOUSE

Accession

Primary (citable) accession number: Q9D415
Secondary accession number(s): Q52KF6 , Q5DTK5, Q6P6N4, Q6XBF4, Q8BZL7, Q8BZQ1, Q8C0G0

Entry history

Integrated into UniProtKB/Swiss-Prot:	September 26, 2001
Last sequence update:	July 19, 2005
Last modified:	April 3, 2013
This is version 98 of the entry and version 3 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Chordata Protein Annotation Program