Reviewed, UniProtKB/Swiss-Prot Q9D3S5 (CN148_MOUSE)

Names and origin

Protein names	Recommended name:     Pyrroline-5-carboxylate reductase-like protein C14orf148 homolog     EC=1.-.-.-
Organism	Mus musculus (Mouse)
Taxonomic identifier	10090 [NCBI]
Taxonomic lineage	Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Glires › Rodentia › Sciurognathi › Muroidea › Muridae › Murinae › Mus

Protein attributes

Sequence length	366 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Evidence at transcript level.

General annotation (Comments)

Function	Probable oxidoreductase By similarity.
Sequence similarities	Belongs to the pyrroline-5-carboxylate reductase family.

Ontologies

Keywords
Molecular function	Oxidoreductase
Gene Ontology (GO)
Biological process	oxidation reduction Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	binding Inferred from electronic annotation. Source: InterPro oxidoreductase activity Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 366	366	Pyrroline-5-carboxylate reductase-like protein C14orf148 homolog		PRO_0000280280

Sequences

	Sequence		Length	Mass (Da)
	Q9D3S5-1 [UniParc]. Last modified June 1, 2001. Version 1. Checksum: AF86FD2D1979611B	FASTA	366	41,666
	10 20 30 40 50 60 MEMLEDLESL RFEFGIPEEE RYWLYLQGRY RGLMIKGCAH AAFFCKMFST LSNLLQNLPR 70 80 90 100 110 120 TIHPRTVSFD NAATEDELLT VGIIGCGHLG KQLTNVLLKT VPIPAENLQI STRRPESLGE 130 140 150 160 170 180 LRKLGVRCVY DNAAVASWAK VLFLCCLPAQ LPNICLEIQS KLNKHCTVYS FVSAIPLPRL 190 200 210 220 230 240 KSLLNHTNIL RPQYQFAEDY DNIWGENEEV PIALQDTTII RGTCPYNNLG GVILNVKWIE 250 260 270 280 290 300 GLCYALINAC TSRSVFHSQV LKLLNKLLLP MHLESCTTDP ESCPQFNLTD FMSKSYVKNL 310 320 330 340 350 360 YQKRPFPWFD LTTVQLKETP FSQHISATPS LQDHISLLYC EVFGLTISEE ELPYISTVIR PLVEEK

References

[1]

"The transcriptional landscape of the mammalian genome." Carninci P., Kasukawa T., Katayama S., Gough J., Frith M.C., Maeda N., Oyama R., Ravasi T., Lenhard B., Wells C., Kodzius R., Shimokawa K., Bajic V.B., Brenner S.E., Batalov S., Forrest A.R., Zavolan M., Davis M.J. , Wilming L.G., Aidinis V., Allen J.E., Ambesi-Impiombato A., Apweiler R., Aturaliya R.N., Bailey T.L., Bansal M., Baxter L., Beisel K.W., Bersano T., Bono H., Chalk A.M., Chiu K.P., Choudhary V., Christoffels A., Clutterbuck D.R., Crowe M.L., Dalla E., Dalrymple B.P., de Bono B., Della Gatta G., di Bernardo D., Down T., Engstrom P., Fagiolini M., Faulkner G., Fletcher C.F., Fukushima T., Furuno M., Futaki S., Gariboldi M., Georgii-Hemming P., Gingeras T.R., Gojobori T., Green R.E., Gustincich S., Harbers M., Hayashi Y., Hensch T.K., Hirokawa N., Hill D., Huminiecki L., Iacono M., Ikeo K., Iwama A., Ishikawa T., Jakt M., Kanapin A., Katoh M., Kawasawa Y., Kelso J., Kitamura H., Kitano H., Kollias G., Krishnan S.P., Kruger A., Kummerfeld S.K., Kurochkin I.V., Lareau L.F., Lazarevic D., Lipovich L., Liu J., Liuni S., McWilliam S., Madan Babu M., Madera M., Marchionni L., Matsuda H., Matsuzawa S., Miki H., Mignone F., Miyake S., Morris K., Mottagui-Tabar S., Mulder N., Nakano N., Nakauchi H., Ng P., Nilsson R., Nishiguchi S., Nishikawa S., Nori F., Ohara O., Okazaki Y., Orlando V., Pang K.C., Pavan W.J., Pavesi G., Pesole G., Petrovsky N., Piazza S., Reed J., Reid J.F., Ring B.Z., Ringwald M., Rost B., Ruan Y., Salzberg S.L., Sandelin A., Schneider C., Schoenbach C., Sekiguchi K., Semple C.A., Seno S., Sessa L., Sheng Y., Shibata Y., Shimada H., Shimada K., Silva D., Sinclair B., Sperling S., Stupka E., Sugiura K., Sultana R., Takenaka Y., Taki K., Tammoja K., Tan S.L., Tang S., Taylor M.S., Tegner J., Teichmann S.A., Ueda H.R., van Nimwegen E., Verardo R., Wei C.L., Yagi K., Yamanishi H., Zabarovsky E., Zhu S., Zimmer A., Hide W., Bult C., Grimmond S.M., Teasdale R.D., Liu E.T., Brusic V., Quackenbush J., Wahlestedt C., Mattick J.S., Hume D.A., Kai C., Sasaki D., Tomaru Y., Fukuda S., Kanamori-Katayama M., Suzuki M., Aoki J., Arakawa T., Iida J., Imamura K., Itoh M., Kato T., Kawaji H., Kawagashira N., Kawashima T., Kojima M., Kondo S., Konno H., Nakano K., Ninomiya N., Nishio T., Okada M., Plessy C., Shibata K., Shiraki T., Suzuki S., Tagami M., Waki K., Watahiki A., Okamura-Oho Y., Suzuki H., Kawai J., Hayashizaki Y. Science 309:1559-1563(2005) [PubMed: 16141072] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]. Strain: C57BL/6J. Tissue: Testis.

[2]

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)." The MGC Project Team Genome Res. 14:2121-2127(2004) [PubMed: 15489334] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]. Tissue: Brain.

Cross-references

Sequence databases
EMBLGenBankDDBJ	AK017096 mRNA. Translation: BAB30594.1. BC125331 mRNA. Translation: AAI25332.1. BC125333 mRNA. Translation: AAI25334.1.
IPI	IPI00136469.
RefSeq	NP_082020.1.
UniGene	Mm.79198
3D structure databases
ModBase	Search...
Genome annotation databases
Ensembl	ENSMUSG00000072919. Mus musculus. [Contig view]
GeneID	71275.
KEGG	mmu:71275.
Organism-specific databases
MGI	MGI:1918525. 4933437F05Rik.
Phylogenomic databases
HOVERGEN	Q9D3S5.
OMA	Q9D3S5. ACAHATF.
Gene expression databases
ArrayExpress	Q9D3S5.
Bgee	Q9D3S5.
CleanEx	MM_4933437F05RIK.
Family and domain databases
InterPro	IPR004455. NADP_OxRdtase_F420. IPR000304. P5CR. [Graphical view]
Pfam	PF03807. F420_oxidored. 1 hit. [Graphical view]
PROSITE	PS00521. P5CR. False negative. [Graphical view]
ProtoNet	Search...
Other Resources
NextBio	333423.

Entry information

Entry name

CN148_MOUSE

Accession

Primary (citable) accession number: Q9D3S5

Entry history

Integrated into UniProtKB/Swiss-Prot:	March 20, 2007
Last sequence update:	June 1, 2001
Last modified:	May 5, 2009
This is version 46 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HPI (Human Proteome Initiative)