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Q9D3S5 (NXRD1_MOUSE) Reviewed, UniProtKB/Swiss-Prot

Last modified December 14, 2011. Version 65. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
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to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
NADP-dependent oxidoreductase domain-containing protein 1
EC=1.-.-.-
Alternative name(s):
Pyrroline-5-carboxylate reductase-like protein C14orf148 homolog
Gene names
Name:Noxred1
OrganismMus musculus (Mouse)
Taxonomic identifier10090 [NCBI]
Taxonomic lineageEukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Glires › Rodentia › Sciurognathi › Muroidea › Muridae › Murinae › Mus › Mus

Protein attributes

Sequence length366 AA.
Sequence statusComplete.
Protein existenceEvidence at transcript level

General annotation (Comments)

Function

Probable oxidoreductase By similarity.

Sequence similarities

Belongs to the pyrroline-5-carboxylate reductase family.

Ontologies

Keywords
   Molecular functionOxidoreductase
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Biological processproline biosynthetic process

Inferred from electronic annotation. Source: InterPro

   Molecular functionnucleotide binding

Inferred from electronic annotation. Source: InterPro

pyrroline-5-carboxylate reductase activity

Inferred from electronic annotation. Source: InterPro

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 366366NADP-dependent oxidoreductase domain-containing protein 1
PRO_0000280280

Sequences

Sequence LengthMass (Da)Tools
Q9D3S5 [UniParc].

Last modified June 1, 2001. Version 1.
Checksum: AF86FD2D1979611B

FASTA36641,666
        10         20         30         40         50         60 
MEMLEDLESL RFEFGIPEEE RYWLYLQGRY RGLMIKGCAH AAFFCKMFST LSNLLQNLPR 

        70         80         90        100        110        120 
TIHPRTVSFD NAATEDELLT VGIIGCGHLG KQLTNVLLKT VPIPAENLQI STRRPESLGE 

       130        140        150        160        170        180 
LRKLGVRCVY DNAAVASWAK VLFLCCLPAQ LPNICLEIQS KLNKHCTVYS FVSAIPLPRL 

       190        200        210        220        230        240 
KSLLNHTNIL RPQYQFAEDY DNIWGENEEV PIALQDTTII RGTCPYNNLG GVILNVKWIE 

       250        260        270        280        290        300 
GLCYALINAC TSRSVFHSQV LKLLNKLLLP MHLESCTTDP ESCPQFNLTD FMSKSYVKNL 

       310        320        330        340        350        360 
YQKRPFPWFD LTTVQLKETP FSQHISATPS LQDHISLLYC EVFGLTISEE ELPYISTVIR 


PLVEEK

« Hide

References

[1]"The transcriptional landscape of the mammalian genome."
Carninci P., Kasukawa T., Katayama S., Gough J., Frith M.C., Maeda N., Oyama R., Ravasi T., Lenhard B., Wells C., Kodzius R., Shimokawa K., Bajic V.B., Brenner S.E., Batalov S., Forrest A.R., Zavolan M., Davis M.J. expand/collapse author list , Wilming L.G., Aidinis V., Allen J.E., Ambesi-Impiombato A., Apweiler R., Aturaliya R.N., Bailey T.L., Bansal M., Baxter L., Beisel K.W., Bersano T., Bono H., Chalk A.M., Chiu K.P., Choudhary V., Christoffels A., Clutterbuck D.R., Crowe M.L., Dalla E., Dalrymple B.P., de Bono B., Della Gatta G., di Bernardo D., Down T., Engstrom P., Fagiolini M., Faulkner G., Fletcher C.F., Fukushima T., Furuno M., Futaki S., Gariboldi M., Georgii-Hemming P., Gingeras T.R., Gojobori T., Green R.E., Gustincich S., Harbers M., Hayashi Y., Hensch T.K., Hirokawa N., Hill D., Huminiecki L., Iacono M., Ikeo K., Iwama A., Ishikawa T., Jakt M., Kanapin A., Katoh M., Kawasawa Y., Kelso J., Kitamura H., Kitano H., Kollias G., Krishnan S.P., Kruger A., Kummerfeld S.K., Kurochkin I.V., Lareau L.F., Lazarevic D., Lipovich L., Liu J., Liuni S., McWilliam S., Madan Babu M., Madera M., Marchionni L., Matsuda H., Matsuzawa S., Miki H., Mignone F., Miyake S., Morris K., Mottagui-Tabar S., Mulder N., Nakano N., Nakauchi H., Ng P., Nilsson R., Nishiguchi S., Nishikawa S., Nori F., Ohara O., Okazaki Y., Orlando V., Pang K.C., Pavan W.J., Pavesi G., Pesole G., Petrovsky N., Piazza S., Reed J., Reid J.F., Ring B.Z., Ringwald M., Rost B., Ruan Y., Salzberg S.L., Sandelin A., Schneider C., Schoenbach C., Sekiguchi K., Semple C.A., Seno S., Sessa L., Sheng Y., Shibata Y., Shimada H., Shimada K., Silva D., Sinclair B., Sperling S., Stupka E., Sugiura K., Sultana R., Takenaka Y., Taki K., Tammoja K., Tan S.L., Tang S., Taylor M.S., Tegner J., Teichmann S.A., Ueda H.R., van Nimwegen E., Verardo R., Wei C.L., Yagi K., Yamanishi H., Zabarovsky E., Zhu S., Zimmer A., Hide W., Bult C., Grimmond S.M., Teasdale R.D., Liu E.T., Brusic V., Quackenbush J., Wahlestedt C., Mattick J.S., Hume D.A., Kai C., Sasaki D., Tomaru Y., Fukuda S., Kanamori-Katayama M., Suzuki M., Aoki J., Arakawa T., Iida J., Imamura K., Itoh M., Kato T., Kawaji H., Kawagashira N., Kawashima T., Kojima M., Kondo S., Konno H., Nakano K., Ninomiya N., Nishio T., Okada M., Plessy C., Shibata K., Shiraki T., Suzuki S., Tagami M., Waki K., Watahiki A., Okamura-Oho Y., Suzuki H., Kawai J., Hayashizaki Y.
Science 309:1559-1563(2005) [PubMed: 16141072] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
Strain: C57BL/6J.
Tissue: Testis.
[2]"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res. 14:2121-2127(2004) [PubMed: 15489334] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
Tissue: Brain.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		AK017096 mRNA. Translation: BAB30594.1.
BC125331 mRNA. Translation: AAI25332.1.
BC125333 mRNA. Translation: AAI25334.1.
IPIIPI00136469.
RefSeqNP_082020.1. NM_027744.1.
UniGeneMm.79198.

3D structure databases

ProteinModelPortalQ9D3S5.
SMRQ9D3S5. Positions 77-170.
ModBaseSearch...

Proteomic databases

PRIDEQ9D3S5.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblENSMUST00000021423; ENSMUSP00000021423; ENSMUSG00000072919.
GeneID71275.
KEGGmmu:71275.
UCSCuc007oio.1. mouse.

Organism-specific databases

MGIMGI:1918525. 4933437F05Rik.

Phylogenomic databases

eggNOGroNOG14392.
GeneTreeENSGT00390000007632.
HOGENOMHBG444679.
HOVERGENHBG081280.
InParanoidQ9D3S5.
OMAACAHATF.
OrthoDBEOG4VQ9PQ.
PhylomeDBQ9D3S5.

Gene expression databases

ArrayExpressQ9D3S5.
BgeeQ9D3S5.
CleanExMM_4933437F05RIK.
GenevestigatorQ9D3S5.

Family and domain databases

InterProIPR016040. NAD(P)-bd_dom.
IPR004455. NADP_OxRdtase_F420.
IPR000304. Pyrroline-COOH_reductase.
[Graphical view]
Gene3DG3DSA:3.40.50.720. NAD(P)-bd. 1 hit.
PANTHERPTHR11645. P5CR. 1 hit.
PfamPF03807. F420_oxidored. 1 hit.
[Graphical view]
PROSITEPS00521. P5CR. False negative.
[Graphical view]
ProtoNetSearch...

Other

NextBio333423.
SOURCESearch...

Entry information

Entry nameNXRD1_MOUSE
AccessionPrimary (citable) accession number: Q9D3S5
Entry history
Integrated into UniProtKB/Swiss-Prot: March 20, 2007
Last sequence update: June 1, 2001
Last modified: December 14, 2011
This is version 65 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Relevant documents

MGD cross-references

Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot

SIMILARITY comments

Index of protein domains and families

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