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Q9D3G5

- STX11_MOUSE

UniProt

Q9D3G5 - STX11_MOUSE

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Protein
Syntaxin-11
Gene
Stx11
Organism
Mus musculus (Mouse)
Status
Reviewed - Annotation score: 3 out of 5 - Experimental evidence at transcript leveli

Functioni

SNARE that acts to regulate protein transport between late endosomes and the trans-Golgi network By similarity.

GO - Biological processi

  1. T cell mediated cytotoxicity Source: MGI
  2. cytotoxic T cell degranulation Source: MGI
  3. intracellular protein transport Source: InterPro
  4. natural killer cell degranulation Source: MGI
  5. natural killer cell mediated cytotoxicity Source: MGI
  6. neutrophil degranulation Source: MGI
Complete GO annotation...

Keywords - Biological processi

Protein transport, Transport

Names & Taxonomyi

Protein namesi
Recommended name:
Syntaxin-11
Gene namesi
Name:Stx11
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
ProteomesiUP000000589: Unplaced

Organism-specific databases

MGIiMGI:1921982. Stx11.

Subcellular locationi

GO - Cellular componenti

  1. Golgi apparatus Source: UniProtKB-SubCell
  2. membrane Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Golgi apparatus, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 287287Syntaxin-11
PRO_0000210222Add
BLAST

Proteomic databases

PaxDbiQ9D3G5.
PRIDEiQ9D3G5.

PTM databases

PhosphoSiteiQ9D3G5.

Expressioni

Gene expression databases

CleanExiMM_STX11.
GenevestigatoriQ9D3G5.

Interactioni

Subunit structurei

Interacts with the SNARE proteins SNAP-23 and VAMP By similarity.

Structurei

3D structure databases

ProteinModelPortaliQ9D3G5.
SMRiQ9D3G5. Positions 38-286.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini204 – 26663t-SNARE coiled-coil homology
Add
BLAST

Coiled coil

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Coiled coili41 – 7131 Reviewed prediction
Add
BLAST

Sequence similaritiesi

Belongs to the syntaxin family.

Keywords - Domaini

Coiled coil

Phylogenomic databases

eggNOGiNOG296694.
HOGENOMiHOG000286023.
HOVERGENiHBG099780.
InParanoidiQ9D3G5.
KOiK08487.
PhylomeDBiQ9D3G5.

Family and domain databases

InterProiIPR028672. STX11.
IPR006012. Syntaxin/epimorphin_CS.
IPR006011. Syntaxin_N.
IPR010989. t-SNARE.
IPR000727. T_SNARE_dom.
[Graphical view]
PANTHERiPTHR19957:SF30. PTHR19957:SF30. 1 hit.
PfamiPF05739. SNARE. 1 hit.
PF00804. Syntaxin. 1 hit.
[Graphical view]
SMARTiSM00503. SynN. 1 hit.
SM00397. t_SNARE. 1 hit.
[Graphical view]
SUPFAMiSSF47661. SSF47661. 1 hit.
PROSITEiPS00914. SYNTAXIN. 1 hit.
PS50192. T_SNARE. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q9D3G5-1 [UniParc]FASTAAdd to Basket

« Hide

MKDRLAELQE LSRSYDQQFP DGDNDFDAPR EDIVFETDNI LESLYRVIQD    50
IQDENQLLLI DVRRLGRQNV RFLTSMRRLS SIKRDTNSIA KAIKTRGEGI 100
HQKLRSMKEL SEQAEARHGA HSAVARISHA QYSALARAFQ QAMYEYNQAE 150
MKQRDNCKIR IQRQLEIMGK DMSGEQIEDM FEQGKWDVFS ENLLADLKGA 200
RAALNEIESR HRELLRLEGR IRDVHELFLQ MAVLVEKQED TLNVIELNVQ 250
KTLDYTGEAK AQVRKAVQYK KKNPCRTICC FCCPCVN 287
Length:287
Mass (Da):33,369
Last modified:June 1, 2001 - v1
Checksum:iFD5D10842B7C5415
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AK017897 mRNA. Translation: BAB30994.1.
CCDSiCCDS48500.1.
RefSeqiNP_083351.1. NM_029075.1.
UniGeneiMm.248648.

Genome annotation databases

GeneIDi74732.
KEGGimmu:74732.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AK017897 mRNA. Translation: BAB30994.1 .
CCDSi CCDS48500.1.
RefSeqi NP_083351.1. NM_029075.1.
UniGenei Mm.248648.

3D structure databases

ProteinModelPortali Q9D3G5.
SMRi Q9D3G5. Positions 38-286.
ModBasei Search...
MobiDBi Search...

PTM databases

PhosphoSitei Q9D3G5.

Proteomic databases

PaxDbi Q9D3G5.
PRIDEi Q9D3G5.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

GeneIDi 74732.
KEGGi mmu:74732.

Organism-specific databases

CTDi 8676.
MGIi MGI:1921982. Stx11.

Phylogenomic databases

eggNOGi NOG296694.
HOGENOMi HOG000286023.
HOVERGENi HBG099780.
InParanoidi Q9D3G5.
KOi K08487.
PhylomeDBi Q9D3G5.

Miscellaneous databases

NextBioi 341502.
PROi Q9D3G5.
SOURCEi Search...

Gene expression databases

CleanExi MM_STX11.
Genevestigatori Q9D3G5.

Family and domain databases

InterProi IPR028672. STX11.
IPR006012. Syntaxin/epimorphin_CS.
IPR006011. Syntaxin_N.
IPR010989. t-SNARE.
IPR000727. T_SNARE_dom.
[Graphical view ]
PANTHERi PTHR19957:SF30. PTHR19957:SF30. 1 hit.
Pfami PF05739. SNARE. 1 hit.
PF00804. Syntaxin. 1 hit.
[Graphical view ]
SMARTi SM00503. SynN. 1 hit.
SM00397. t_SNARE. 1 hit.
[Graphical view ]
SUPFAMi SSF47661. SSF47661. 1 hit.
PROSITEi PS00914. SYNTAXIN. 1 hit.
PS50192. T_SNARE. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "The transcriptional landscape of the mammalian genome."
    Carninci P., Kasukawa T., Katayama S., Gough J., Frith M.C., Maeda N., Oyama R., Ravasi T., Lenhard B., Wells C., Kodzius R., Shimokawa K., Bajic V.B., Brenner S.E., Batalov S., Forrest A.R., Zavolan M., Davis M.J.
    , Wilming L.G., Aidinis V., Allen J.E., Ambesi-Impiombato A., Apweiler R., Aturaliya R.N., Bailey T.L., Bansal M., Baxter L., Beisel K.W., Bersano T., Bono H., Chalk A.M., Chiu K.P., Choudhary V., Christoffels A., Clutterbuck D.R., Crowe M.L., Dalla E., Dalrymple B.P., de Bono B., Della Gatta G., di Bernardo D., Down T., Engstrom P., Fagiolini M., Faulkner G., Fletcher C.F., Fukushima T., Furuno M., Futaki S., Gariboldi M., Georgii-Hemming P., Gingeras T.R., Gojobori T., Green R.E., Gustincich S., Harbers M., Hayashi Y., Hensch T.K., Hirokawa N., Hill D., Huminiecki L., Iacono M., Ikeo K., Iwama A., Ishikawa T., Jakt M., Kanapin A., Katoh M., Kawasawa Y., Kelso J., Kitamura H., Kitano H., Kollias G., Krishnan S.P., Kruger A., Kummerfeld S.K., Kurochkin I.V., Lareau L.F., Lazarevic D., Lipovich L., Liu J., Liuni S., McWilliam S., Madan Babu M., Madera M., Marchionni L., Matsuda H., Matsuzawa S., Miki H., Mignone F., Miyake S., Morris K., Mottagui-Tabar S., Mulder N., Nakano N., Nakauchi H., Ng P., Nilsson R., Nishiguchi S., Nishikawa S., Nori F., Ohara O., Okazaki Y., Orlando V., Pang K.C., Pavan W.J., Pavesi G., Pesole G., Petrovsky N., Piazza S., Reed J., Reid J.F., Ring B.Z., Ringwald M., Rost B., Ruan Y., Salzberg S.L., Sandelin A., Schneider C., Schoenbach C., Sekiguchi K., Semple C.A., Seno S., Sessa L., Sheng Y., Shibata Y., Shimada H., Shimada K., Silva D., Sinclair B., Sperling S., Stupka E., Sugiura K., Sultana R., Takenaka Y., Taki K., Tammoja K., Tan S.L., Tang S., Taylor M.S., Tegner J., Teichmann S.A., Ueda H.R., van Nimwegen E., Verardo R., Wei C.L., Yagi K., Yamanishi H., Zabarovsky E., Zhu S., Zimmer A., Hide W., Bult C., Grimmond S.M., Teasdale R.D., Liu E.T., Brusic V., Quackenbush J., Wahlestedt C., Mattick J.S., Hume D.A., Kai C., Sasaki D., Tomaru Y., Fukuda S., Kanamori-Katayama M., Suzuki M., Aoki J., Arakawa T., Iida J., Imamura K., Itoh M., Kato T., Kawaji H., Kawagashira N., Kawashima T., Kojima M., Kondo S., Konno H., Nakano K., Ninomiya N., Nishio T., Okada M., Plessy C., Shibata K., Shiraki T., Suzuki S., Tagami M., Waki K., Watahiki A., Okamura-Oho Y., Suzuki H., Kawai J., Hayashizaki Y.
    Science 309:1559-1563(2005) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Strain: C57BL/6J.
    Tissue: Thymus.

Entry informationi

Entry nameiSTX11_MOUSE
AccessioniPrimary (citable) accession number: Q9D3G5
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 10, 2004
Last sequence update: June 1, 2001
Last modified: July 9, 2014
This is version 89 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi