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Protein

U11/U12 small nuclear ribonucleoprotein 35 kDa protein

Gene

Snrnp35

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Biological processi

mRNA processing, mRNA splicing

Keywords - Ligandi

RNA-binding

Enzyme and pathway databases

ReactomeiR-MMU-72165. mRNA Splicing - Minor Pathway.

Names & Taxonomyi

Protein namesi
Recommended name:
U11/U12 small nuclear ribonucleoprotein 35 kDa protein
Short name:
U11/U12 snRNP 35 kDa protein
Alternative name(s):
U1 snRNP-binding protein homolog
Gene namesi
Name:Snrnp35
Synonyms:U1snrnpbp
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 5

Organism-specific databases

MGIiMGI:1923417. Snrnp35.

Subcellular locationi

GO - Cellular componenti

  • commitment complex Source: GO_Central
  • nucleus Source: MGI
  • precatalytic spliceosome Source: GO_Central
  • U12-type spliceosomal complex Source: HGNC
Complete GO annotation...

Keywords - Cellular componenti

Nucleus, Spliceosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 244244U11/U12 small nuclear ribonucleoprotein 35 kDa proteinPRO_0000307908Add
BLAST

Proteomic databases

EPDiQ9D384.
MaxQBiQ9D384.
PaxDbiQ9D384.
PeptideAtlasiQ9D384.
PRIDEiQ9D384.

PTM databases

PhosphoSiteiQ9D384.

Expressioni

Gene expression databases

BgeeiENSMUSG00000029402.
ExpressionAtlasiQ9D384. baseline and differential.
GenevisibleiQ9D384. MM.

Interactioni

Subunit structurei

Component of the U11/U12 snRNPs that are part of the U12-type spliceosome.By similarity

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000031349.

Structurei

3D structure databases

ProteinModelPortaliQ9D384.
SMRiQ9D384. Positions 47-139.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini51 – 12979RRMPROSITE-ProRule annotationAdd
BLAST

Compositional bias

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Compositional biasi154 – 24289Arg-richAdd
BLAST

Sequence similaritiesi

Contains 1 RRM (RNA recognition motif) domain.PROSITE-ProRule annotation

Phylogenomic databases

eggNOGiKOG0113. Eukaryota.
COG0724. LUCA.
GeneTreeiENSGT00530000063750.
HOGENOMiHOG000006374.
HOVERGENiHBG104583.
InParanoidiQ9D384.
KOiK13155.
OMAiYTPNKGV.
OrthoDBiEOG091G0NV3.
PhylomeDBiQ9D384.
TreeFamiTF331614.

Family and domain databases

Gene3Di3.30.70.330. 1 hit.
InterProiIPR012677. Nucleotide-bd_a/b_plait.
IPR000504. RRM_dom.
[Graphical view]
PfamiPF00076. RRM_1. 1 hit.
[Graphical view]
SMARTiSM00360. RRM. 1 hit.
[Graphical view]
SUPFAMiSSF54928. SSF54928. 1 hit.
PROSITEiPS50102. RRM. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q9D384-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSDWMPIAKE YDPLKAGSID GTDEDPHDRA VWRAMLARYV PNKGVTGDPL
60 70 80 90 100
LTLFVARLNL QTKEEKLKEV FSRYGDIRRL RLVRDLVTGF SKGYAFIEYK
110 120 130 140 150
EERALMKAYR DADGLVIDQH EIFVDYELER TLRGWIPRRL GGGLGGKKES
160 170 180 190 200
GQLRFGGRDR PFRKPINLPV VKNEPHREGK RERRERSRSR DRHWDPRPRE
210 220 230 240
RDHDRGREKH WQERARVWPE NDWEREREFR EERVKSRDKR DRSK
Length:244
Mass (Da):29,290
Last modified:June 1, 2001 - v1
Checksum:i1625D74743CE1245
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK018232 mRNA. Translation: BAB31127.1.
AK039064 mRNA. Translation: BAC30228.1.
BC043031 mRNA. Translation: AAH43031.1.
BC058361 mRNA. Translation: AAH58361.1.
CCDSiCCDS19677.1.
RefSeqiNP_083808.1. NM_029532.2.
XP_006530557.1. XM_006530494.2.
XP_006530558.1. XM_006530495.2.
UniGeneiMm.156035.

Genome annotation databases

EnsembliENSMUST00000031349; ENSMUSP00000031349; ENSMUSG00000029402.
ENSMUST00000111453; ENSMUSP00000107080; ENSMUSG00000029402.
GeneIDi76167.
KEGGimmu:76167.
UCSCiuc008zpy.1. mouse.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK018232 mRNA. Translation: BAB31127.1.
AK039064 mRNA. Translation: BAC30228.1.
BC043031 mRNA. Translation: AAH43031.1.
BC058361 mRNA. Translation: AAH58361.1.
CCDSiCCDS19677.1.
RefSeqiNP_083808.1. NM_029532.2.
XP_006530557.1. XM_006530494.2.
XP_006530558.1. XM_006530495.2.
UniGeneiMm.156035.

3D structure databases

ProteinModelPortaliQ9D384.
SMRiQ9D384. Positions 47-139.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000031349.

PTM databases

PhosphoSiteiQ9D384.

Proteomic databases

EPDiQ9D384.
MaxQBiQ9D384.
PaxDbiQ9D384.
PeptideAtlasiQ9D384.
PRIDEiQ9D384.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000031349; ENSMUSP00000031349; ENSMUSG00000029402.
ENSMUST00000111453; ENSMUSP00000107080; ENSMUSG00000029402.
GeneIDi76167.
KEGGimmu:76167.
UCSCiuc008zpy.1. mouse.

Organism-specific databases

CTDi11066.
MGIiMGI:1923417. Snrnp35.

Phylogenomic databases

eggNOGiKOG0113. Eukaryota.
COG0724. LUCA.
GeneTreeiENSGT00530000063750.
HOGENOMiHOG000006374.
HOVERGENiHBG104583.
InParanoidiQ9D384.
KOiK13155.
OMAiYTPNKGV.
OrthoDBiEOG091G0NV3.
PhylomeDBiQ9D384.
TreeFamiTF331614.

Enzyme and pathway databases

ReactomeiR-MMU-72165. mRNA Splicing - Minor Pathway.

Miscellaneous databases

ChiTaRSiSnrnp35. mouse.
PROiQ9D384.
SOURCEiSearch...

Gene expression databases

BgeeiENSMUSG00000029402.
ExpressionAtlasiQ9D384. baseline and differential.
GenevisibleiQ9D384. MM.

Family and domain databases

Gene3Di3.30.70.330. 1 hit.
InterProiIPR012677. Nucleotide-bd_a/b_plait.
IPR000504. RRM_dom.
[Graphical view]
PfamiPF00076. RRM_1. 1 hit.
[Graphical view]
SMARTiSM00360. RRM. 1 hit.
[Graphical view]
SUPFAMiSSF54928. SSF54928. 1 hit.
PROSITEiPS50102. RRM. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiU1SBP_MOUSE
AccessioniPrimary (citable) accession number: Q9D384
Secondary accession number(s): Q8CAC7
Entry historyi
Integrated into UniProtKB/Swiss-Prot: October 23, 2007
Last sequence update: June 1, 2001
Last modified: September 7, 2016
This is version 115 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.