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Q9D2C9

- SNPC3_MOUSE

UniProt

Q9D2C9 - SNPC3_MOUSE

Protein

snRNA-activating protein complex subunit 3

Gene

Snapc3

Organism
Mus musculus (Mouse)
Status
Reviewed - Annotation score: 2 out of 5- Experimental evidence at transcript leveli
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    • History
      Entry version 81 (01 Oct 2014)
      Sequence version 2 (01 Mar 2003)
      Previous versions | rss
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    Functioni

    Part of the SNAPc complex required for the transcription of both RNA polymerase II and III small-nuclear RNA genes. Binds to the proximal sequence element (PSE), a non-TATA-box basal promoter element common to these 2 types of genes. Recruits TBP and BRF2 to the U6 snRNA TATA box By similarity.By similarity

    GO - Molecular functioni

    1. DNA binding Source: UniProtKB-KW

    GO - Biological processi

    1. regulation of transcription, DNA-templated Source: UniProtKB-KW
    2. transcription, DNA-templated Source: UniProtKB-KW

    Keywords - Biological processi

    Transcription, Transcription regulation

    Keywords - Ligandi

    DNA-binding

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    snRNA-activating protein complex subunit 3
    Short name:
    SNAPc subunit 3
    Alternative name(s):
    Small nuclear RNA-activating complex polypeptide 3
    Gene namesi
    Name:Snapc3
    OrganismiMus musculus (Mouse)
    Taxonomic identifieri10090 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
    ProteomesiUP000000589: Chromosome 4

    Organism-specific databases

    MGIiMGI:1916338. Snapc3.

    Subcellular locationi

    Nucleus By similarity

    GO - Cellular componenti

    1. nucleus Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Nucleus

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 407407snRNA-activating protein complex subunit 3PRO_0000072026Add
    BLAST

    Proteomic databases

    PRIDEiQ9D2C9.

    PTM databases

    PhosphoSiteiQ9D2C9.

    Expressioni

    Gene expression databases

    ArrayExpressiQ9D2C9.
    BgeeiQ9D2C9.
    GenevestigatoriQ9D2C9.

    Interactioni

    Subunit structurei

    Part of the SNAPc complex composed of 5 subunits: SNAPC1, SNAPC2, SNAPC3, SNAPC4 and SNAPC5. SNAPC3 interacts with SNAPC1 By similarity.By similarity

    Structurei

    3D structure databases

    ProteinModelPortaliQ9D2C9.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the SNAPC3/SRD2 family.Curated

    Phylogenomic databases

    eggNOGiNOG312262.
    GeneTreeiENSGT00390000005708.
    HOGENOMiHOG000146435.
    HOVERGENiHBG071400.
    InParanoidiQ9D2C9.
    KOiK15210.
    OMAiNIFYPVI.
    OrthoDBiEOG73RBB7.
    TreeFamiTF317705.

    Family and domain databases

    InterProiIPR022042. snRNA-activating_su3.
    [Graphical view]
    PANTHERiPTHR13421. PTHR13421. 1 hit.
    PfamiPF12251. zf-SNAP50_C. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q9D2C9-1 [UniParc]FASTAAdd to Basket

    « Hide

    MAEDLQGGGA GGPQHPVPSA SHSSFPEYEL PELHTRVFHV GSFGELWRGR    50
    LGAQDLSLSE PQAAEQPTDG GASNDGFEDA AVASDLGCSL EAAAELRVVC 100
    GLDKLRCLGE DEDPEVIPEN TDLVTLCVRK GLLDYREENI TIDRACRQEI 150
    FAYEMESHAL GKKPENPADM IEEGECILSV NILYPVIFNK HKEHKPYQTM 200
    LVLGSQKLTE LRDSICCVSD LQIGGEFSNA PDQAPEHISK DLYKSAFFYF 250
    EGTFYNDRRY PECRDLSRTI IEWSESHDRG YGKFQTARME DFTFNDLHIK 300
    LGFPYLYCHQ GDCEHVVVIT DIRLVHHDDC LDRTLYPLLT KKHWLWTRKC 350
    FVCKMYTARW VTNNDTFAPE DPCFFCDVCF RMLHYDSEGN KLGEFLAYPY 400
    VDPGTFN 407
    Length:407
    Mass (Da):46,277
    Last modified:March 1, 2003 - v2
    Checksum:i8BC79D553C7F5A7D
    GO

    Experimental Info

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Sequence conflicti255 – 2551Y → C in BAC27585. (PubMed:16141072)Curated

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AK019863 mRNA. Translation: BAB31890.2.
    AK031870 mRNA. Translation: BAC27585.1.
    AK049933 mRNA. Translation: BAC33990.1.
    BC048713 mRNA. Translation: AAH48713.1.
    CCDSiCCDS38792.1.
    RefSeqiNP_084225.1. NM_029949.3.
    XP_006538432.1. XM_006538369.1.
    XP_006538433.1. XM_006538370.1.
    XP_006538434.1. XM_006538371.1.
    XP_006538435.1. XM_006538372.1.
    UniGeneiMm.271985.
    Mm.482328.

    Genome annotation databases

    EnsembliENSMUST00000030206; ENSMUSP00000030206; ENSMUSG00000028483.
    ENSMUST00000123262; ENSMUSP00000124038; ENSMUSG00000028483.
    ENSMUST00000124856; ENSMUSP00000124181; ENSMUSG00000028483.
    ENSMUST00000143533; ENSMUSP00000123793; ENSMUSG00000028483.
    GeneIDi77634.
    KEGGimmu:77634.
    UCSCiuc008tku.1. mouse.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AK019863 mRNA. Translation: BAB31890.2 .
    AK031870 mRNA. Translation: BAC27585.1 .
    AK049933 mRNA. Translation: BAC33990.1 .
    BC048713 mRNA. Translation: AAH48713.1 .
    CCDSi CCDS38792.1.
    RefSeqi NP_084225.1. NM_029949.3.
    XP_006538432.1. XM_006538369.1.
    XP_006538433.1. XM_006538370.1.
    XP_006538434.1. XM_006538371.1.
    XP_006538435.1. XM_006538372.1.
    UniGenei Mm.271985.
    Mm.482328.

    3D structure databases

    ProteinModelPortali Q9D2C9.
    ModBasei Search...
    MobiDBi Search...

    PTM databases

    PhosphoSitei Q9D2C9.

    Proteomic databases

    PRIDEi Q9D2C9.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    Ensembli ENSMUST00000030206 ; ENSMUSP00000030206 ; ENSMUSG00000028483 .
    ENSMUST00000123262 ; ENSMUSP00000124038 ; ENSMUSG00000028483 .
    ENSMUST00000124856 ; ENSMUSP00000124181 ; ENSMUSG00000028483 .
    ENSMUST00000143533 ; ENSMUSP00000123793 ; ENSMUSG00000028483 .
    GeneIDi 77634.
    KEGGi mmu:77634.
    UCSCi uc008tku.1. mouse.

    Organism-specific databases

    CTDi 6619.
    MGIi MGI:1916338. Snapc3.

    Phylogenomic databases

    eggNOGi NOG312262.
    GeneTreei ENSGT00390000005708.
    HOGENOMi HOG000146435.
    HOVERGENi HBG071400.
    InParanoidi Q9D2C9.
    KOi K15210.
    OMAi NIFYPVI.
    OrthoDBi EOG73RBB7.
    TreeFami TF317705.

    Miscellaneous databases

    ChiTaRSi SNAPC3. mouse.
    NextBioi 347276.
    PROi Q9D2C9.
    SOURCEi Search...

    Gene expression databases

    ArrayExpressi Q9D2C9.
    Bgeei Q9D2C9.
    Genevestigatori Q9D2C9.

    Family and domain databases

    InterProi IPR022042. snRNA-activating_su3.
    [Graphical view ]
    PANTHERi PTHR13421. PTHR13421. 1 hit.
    Pfami PF12251. zf-SNAP50_C. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "The transcriptional landscape of the mammalian genome."
      Carninci P., Kasukawa T., Katayama S., Gough J., Frith M.C., Maeda N., Oyama R., Ravasi T., Lenhard B., Wells C., Kodzius R., Shimokawa K., Bajic V.B., Brenner S.E., Batalov S., Forrest A.R., Zavolan M., Davis M.J.
      , Wilming L.G., Aidinis V., Allen J.E., Ambesi-Impiombato A., Apweiler R., Aturaliya R.N., Bailey T.L., Bansal M., Baxter L., Beisel K.W., Bersano T., Bono H., Chalk A.M., Chiu K.P., Choudhary V., Christoffels A., Clutterbuck D.R., Crowe M.L., Dalla E., Dalrymple B.P., de Bono B., Della Gatta G., di Bernardo D., Down T., Engstrom P., Fagiolini M., Faulkner G., Fletcher C.F., Fukushima T., Furuno M., Futaki S., Gariboldi M., Georgii-Hemming P., Gingeras T.R., Gojobori T., Green R.E., Gustincich S., Harbers M., Hayashi Y., Hensch T.K., Hirokawa N., Hill D., Huminiecki L., Iacono M., Ikeo K., Iwama A., Ishikawa T., Jakt M., Kanapin A., Katoh M., Kawasawa Y., Kelso J., Kitamura H., Kitano H., Kollias G., Krishnan S.P., Kruger A., Kummerfeld S.K., Kurochkin I.V., Lareau L.F., Lazarevic D., Lipovich L., Liu J., Liuni S., McWilliam S., Madan Babu M., Madera M., Marchionni L., Matsuda H., Matsuzawa S., Miki H., Mignone F., Miyake S., Morris K., Mottagui-Tabar S., Mulder N., Nakano N., Nakauchi H., Ng P., Nilsson R., Nishiguchi S., Nishikawa S., Nori F., Ohara O., Okazaki Y., Orlando V., Pang K.C., Pavan W.J., Pavesi G., Pesole G., Petrovsky N., Piazza S., Reed J., Reid J.F., Ring B.Z., Ringwald M., Rost B., Ruan Y., Salzberg S.L., Sandelin A., Schneider C., Schoenbach C., Sekiguchi K., Semple C.A., Seno S., Sessa L., Sheng Y., Shibata Y., Shimada H., Shimada K., Silva D., Sinclair B., Sperling S., Stupka E., Sugiura K., Sultana R., Takenaka Y., Taki K., Tammoja K., Tan S.L., Tang S., Taylor M.S., Tegner J., Teichmann S.A., Ueda H.R., van Nimwegen E., Verardo R., Wei C.L., Yagi K., Yamanishi H., Zabarovsky E., Zhu S., Zimmer A., Hide W., Bult C., Grimmond S.M., Teasdale R.D., Liu E.T., Brusic V., Quackenbush J., Wahlestedt C., Mattick J.S., Hume D.A., Kai C., Sasaki D., Tomaru Y., Fukuda S., Kanamori-Katayama M., Suzuki M., Aoki J., Arakawa T., Iida J., Imamura K., Itoh M., Kato T., Kawaji H., Kawagashira N., Kawashima T., Kojima M., Kondo S., Konno H., Nakano K., Ninomiya N., Nishio T., Okada M., Plessy C., Shibata K., Shiraki T., Suzuki S., Tagami M., Waki K., Watahiki A., Okamura-Oho Y., Suzuki H., Kawai J., Hayashizaki Y.
      Science 309:1559-1563(2005) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
      Strain: C57BL/6J.
      Tissue: Hippocampus, Medulla oblongata, Ovary and Uterus.
    2. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
      Tissue: Embryo.

    Entry informationi

    Entry nameiSNPC3_MOUSE
    AccessioniPrimary (citable) accession number: Q9D2C9
    Secondary accession number(s): Q8C0A5
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: October 25, 2005
    Last sequence update: March 1, 2003
    Last modified: October 1, 2014
    This is version 81 of the entry and version 2 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programChordata Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. MGD cross-references
      Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3