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Q9D2C9 (SNPC3_MOUSE) Reviewed, UniProtKB/Swiss-Prot

Last modified July 9, 2014. Version 80. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
snRNA-activating protein complex subunit 3

Short name=SNAPc subunit 3
Alternative name(s):
Small nuclear RNA-activating complex polypeptide 3
Gene names
Name:Snapc3
OrganismMus musculus (Mouse) [Reference proteome]
Taxonomic identifier10090 [NCBI]
Taxonomic lineageEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus

Protein attributes

Sequence length407 AA.
Sequence statusComplete.
Protein existenceEvidence at transcript level

General annotation (Comments)

Function

Part of the SNAPc complex required for the transcription of both RNA polymerase II and III small-nuclear RNA genes. Binds to the proximal sequence element (PSE), a non-TATA-box basal promoter element common to these 2 types of genes. Recruits TBP and BRF2 to the U6 snRNA TATA box By similarity.

Subunit structure

Part of the SNAPc complex composed of 5 subunits: SNAPC1, SNAPC2, SNAPC3, SNAPC4 and SNAPC5. SNAPC3 interacts with SNAPC1 By similarity.

Subcellular location

Nucleus By similarity.

Sequence similarities

Belongs to the SNAPC3/SRD2 family.

Ontologies

Keywords
   Biological processTranscription
Transcription regulation
   Cellular componentNucleus
   LigandDNA-binding
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Biological_processregulation of transcription, DNA-templated

Inferred from electronic annotation. Source: UniProtKB-KW

transcription, DNA-templated

Inferred from electronic annotation. Source: UniProtKB-KW

   Cellular_componentnucleus

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionDNA binding

Inferred from electronic annotation. Source: UniProtKB-KW

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 407407snRNA-activating protein complex subunit 3
PRO_0000072026

Experimental info

Sequence conflict2551Y → C in BAC27585. Ref.1

Sequences

Sequence LengthMass (Da)Tools
Q9D2C9 [UniParc].

Last modified March 1, 2003. Version 2.
Checksum: 8BC79D553C7F5A7D

FASTA40746,277
        10         20         30         40         50         60 
MAEDLQGGGA GGPQHPVPSA SHSSFPEYEL PELHTRVFHV GSFGELWRGR LGAQDLSLSE 

        70         80         90        100        110        120 
PQAAEQPTDG GASNDGFEDA AVASDLGCSL EAAAELRVVC GLDKLRCLGE DEDPEVIPEN 

       130        140        150        160        170        180 
TDLVTLCVRK GLLDYREENI TIDRACRQEI FAYEMESHAL GKKPENPADM IEEGECILSV 

       190        200        210        220        230        240 
NILYPVIFNK HKEHKPYQTM LVLGSQKLTE LRDSICCVSD LQIGGEFSNA PDQAPEHISK 

       250        260        270        280        290        300 
DLYKSAFFYF EGTFYNDRRY PECRDLSRTI IEWSESHDRG YGKFQTARME DFTFNDLHIK 

       310        320        330        340        350        360 
LGFPYLYCHQ GDCEHVVVIT DIRLVHHDDC LDRTLYPLLT KKHWLWTRKC FVCKMYTARW 

       370        380        390        400 
VTNNDTFAPE DPCFFCDVCF RMLHYDSEGN KLGEFLAYPY VDPGTFN 

« Hide

References

[1]"The transcriptional landscape of the mammalian genome."
Carninci P., Kasukawa T., Katayama S., Gough J., Frith M.C., Maeda N., Oyama R., Ravasi T., Lenhard B., Wells C., Kodzius R., Shimokawa K., Bajic V.B., Brenner S.E., Batalov S., Forrest A.R., Zavolan M., Davis M.J. expand/collapse author list , Wilming L.G., Aidinis V., Allen J.E., Ambesi-Impiombato A., Apweiler R., Aturaliya R.N., Bailey T.L., Bansal M., Baxter L., Beisel K.W., Bersano T., Bono H., Chalk A.M., Chiu K.P., Choudhary V., Christoffels A., Clutterbuck D.R., Crowe M.L., Dalla E., Dalrymple B.P., de Bono B., Della Gatta G., di Bernardo D., Down T., Engstrom P., Fagiolini M., Faulkner G., Fletcher C.F., Fukushima T., Furuno M., Futaki S., Gariboldi M., Georgii-Hemming P., Gingeras T.R., Gojobori T., Green R.E., Gustincich S., Harbers M., Hayashi Y., Hensch T.K., Hirokawa N., Hill D., Huminiecki L., Iacono M., Ikeo K., Iwama A., Ishikawa T., Jakt M., Kanapin A., Katoh M., Kawasawa Y., Kelso J., Kitamura H., Kitano H., Kollias G., Krishnan S.P., Kruger A., Kummerfeld S.K., Kurochkin I.V., Lareau L.F., Lazarevic D., Lipovich L., Liu J., Liuni S., McWilliam S., Madan Babu M., Madera M., Marchionni L., Matsuda H., Matsuzawa S., Miki H., Mignone F., Miyake S., Morris K., Mottagui-Tabar S., Mulder N., Nakano N., Nakauchi H., Ng P., Nilsson R., Nishiguchi S., Nishikawa S., Nori F., Ohara O., Okazaki Y., Orlando V., Pang K.C., Pavan W.J., Pavesi G., Pesole G., Petrovsky N., Piazza S., Reed J., Reid J.F., Ring B.Z., Ringwald M., Rost B., Ruan Y., Salzberg S.L., Sandelin A., Schneider C., Schoenbach C., Sekiguchi K., Semple C.A., Seno S., Sessa L., Sheng Y., Shibata Y., Shimada H., Shimada K., Silva D., Sinclair B., Sperling S., Stupka E., Sugiura K., Sultana R., Takenaka Y., Taki K., Tammoja K., Tan S.L., Tang S., Taylor M.S., Tegner J., Teichmann S.A., Ueda H.R., van Nimwegen E., Verardo R., Wei C.L., Yagi K., Yamanishi H., Zabarovsky E., Zhu S., Zimmer A., Hide W., Bult C., Grimmond S.M., Teasdale R.D., Liu E.T., Brusic V., Quackenbush J., Wahlestedt C., Mattick J.S., Hume D.A., Kai C., Sasaki D., Tomaru Y., Fukuda S., Kanamori-Katayama M., Suzuki M., Aoki J., Arakawa T., Iida J., Imamura K., Itoh M., Kato T., Kawaji H., Kawagashira N., Kawashima T., Kojima M., Kondo S., Konno H., Nakano K., Ninomiya N., Nishio T., Okada M., Plessy C., Shibata K., Shiraki T., Suzuki S., Tagami M., Waki K., Watahiki A., Okamura-Oho Y., Suzuki H., Kawai J., Hayashizaki Y.
Science 309:1559-1563(2005) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
Strain: C57BL/6J.
Tissue: Hippocampus, Medulla oblongata, Ovary and Uterus.
[2]"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
Tissue: Embryo.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AK019863 mRNA. Translation: BAB31890.2.
AK031870 mRNA. Translation: BAC27585.1.
AK049933 mRNA. Translation: BAC33990.1.
BC048713 mRNA. Translation: AAH48713.1.
CCDSCCDS38792.1.
RefSeqNP_084225.1. NM_029949.3.
XP_006538432.1. XM_006538369.1.
XP_006538433.1. XM_006538370.1.
XP_006538434.1. XM_006538371.1.
XP_006538435.1. XM_006538372.1.
UniGeneMm.271985.
Mm.482328.

3D structure databases

ProteinModelPortalQ9D2C9.
ModBaseSearch...
MobiDBSearch...

PTM databases

PhosphoSiteQ9D2C9.

Proteomic databases

PRIDEQ9D2C9.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblENSMUST00000030206; ENSMUSP00000030206; ENSMUSG00000028483.
ENSMUST00000123262; ENSMUSP00000124038; ENSMUSG00000028483.
ENSMUST00000124856; ENSMUSP00000124181; ENSMUSG00000028483.
ENSMUST00000143533; ENSMUSP00000123793; ENSMUSG00000028483.
GeneID77634.
KEGGmmu:77634.
UCSCuc008tku.1. mouse.

Organism-specific databases

CTD6619.
MGIMGI:1916338. Snapc3.

Phylogenomic databases

eggNOGNOG312262.
GeneTreeENSGT00390000005708.
HOGENOMHOG000146435.
HOVERGENHBG071400.
InParanoidQ9D2C9.
KOK15210.
OMANIFYPVI.
OrthoDBEOG73RBB7.
TreeFamTF317705.

Gene expression databases

ArrayExpressQ9D2C9.
BgeeQ9D2C9.
GenevestigatorQ9D2C9.

Family and domain databases

InterProIPR022042. snRNA-activating_su3.
[Graphical view]
PANTHERPTHR13421. PTHR13421. 1 hit.
PfamPF12251. zf-SNAP50_C. 1 hit.
[Graphical view]
ProtoNetSearch...

Other

ChiTaRSSNAPC3. mouse.
NextBio347276.
PROQ9D2C9.
SOURCESearch...

Entry information

Entry nameSNPC3_MOUSE
AccessionPrimary (citable) accession number: Q9D2C9
Secondary accession number(s): Q8C0A5
Entry history
Integrated into UniProtKB/Swiss-Prot: October 25, 2005
Last sequence update: March 1, 2003
Last modified: July 9, 2014
This is version 80 of the entry and version 2 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

MGD cross-references

Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot