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Protein

Trafficking protein particle complex subunit 6B

Gene

Trappc6b

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

May play a role in vesicular transport from endoplasmic reticulum to Golgi.By similarity

GO - Biological processi

Keywordsi

Biological processER-Golgi transport, Transport

Enzyme and pathway databases

ReactomeiR-MMU-204005. COPII (Coat Protein 2) Mediated Vesicle Transport.
R-MMU-8876198. RAB GEFs exchange GTP for GDP on RABs.

Names & Taxonomyi

Protein namesi
Recommended name:
Trafficking protein particle complex subunit 6B
Gene namesi
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 12

Organism-specific databases

MGIiMGI:1925482. Trappc6b.

Subcellular locationi

GO - Cellular componenti

Keywords - Cellular componenti

Endoplasmic reticulum, Golgi apparatus

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002115881 – 158Trafficking protein particle complex subunit 6BAdd BLAST158

Proteomic databases

EPDiQ9D289.
MaxQBiQ9D289.
PaxDbiQ9D289.
PeptideAtlasiQ9D289.
PRIDEiQ9D289.

PTM databases

iPTMnetiQ9D289.
PhosphoSitePlusiQ9D289.

Expressioni

Gene expression databases

BgeeiENSMUSG00000020993.
CleanExiMM_TRAPPC6B.
GenevisibleiQ9D289. MM.

Interactioni

Subunit structurei

Part of the multisubunit TRAPP (transport protein particle) complex. Homodimer. Heterodimer with TRAPPC3 (By similarity). Endoplasmic reticulum (By similarity).By similarity

Protein-protein interaction databases

IntActiQ9D289. 2 interactors.
STRINGi10090.ENSMUSP00000021380.

Structurei

3D structure databases

ProteinModelPortaliQ9D289.
SMRiQ9D289.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiKOG3316. Eukaryota.
ENOG410YUYH. LUCA.
GeneTreeiENSGT00390000012948.
HOGENOMiHOG000200502.
HOVERGENiHBG056159.
InParanoidiQ9D289.
KOiK20304.
OMAiFLWFPCG.
OrthoDBiEOG091G0MJ1.
PhylomeDBiQ9D289.
TreeFamiTF313010.

Family and domain databases

InterProiView protein in InterPro
IPR024096. NO_sig/Golgi_transp_ligand-bd.
IPR007194. TRAPP_component.
PfamiView protein in Pfam
PF04051. TRAPP. 1 hit.
SUPFAMiSSF111126. SSF111126. 1 hit.

Sequencei

Sequence statusi: Complete.

Q9D289-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MADEALFLLL HNEMVSGVYK SAEQGEVENG RCVTKLESMG FRVGQGLIER
60 70 80 90 100
FTKDTARFKD ELDIMKFICK DFWTTVFKKQ IDNLRTNHQG IYVLQDNKFR
110 120 130 140 150
LLIQLSAGKQ YLEHASKYLA FTCGLIRGGL SNLGIKSIVT AEVSSMPACK

FQVMIQKL
Length:158
Mass (Da):17,936
Last modified:June 1, 2001 - v1
Checksum:iDA7A047BC4807B9B
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK020026 mRNA. Translation: BAB31972.1.
AK089083 mRNA. Translation: BAC40741.1.
BC031464 mRNA. Translation: AAH31464.1.
CCDSiCCDS25932.1.
RefSeqiNP_001293146.1. NM_001306217.1.
NP_001293147.1. NM_001306218.1.
NP_084333.1. NM_030057.3.
UniGeneiMm.290070.
Mm.414511.

Genome annotation databases

EnsembliENSMUST00000021380; ENSMUSP00000021380; ENSMUSG00000020993.
GeneIDi78232.
KEGGimmu:78232.
UCSCiuc007npy.1. mouse.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.

Entry informationi

Entry nameiTPC6B_MOUSE
AccessioniPrimary (citable) accession number: Q9D289
Entry historyiIntegrated into UniProtKB/Swiss-Prot: March 15, 2004
Last sequence update: June 1, 2001
Last modified: June 7, 2017
This is version 108 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
  2. SIMILARITY comments
    Index of protein domains and families