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Protein

Trafficking protein particle complex subunit 6B

Gene

Trappc6b

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

May play a role in vesicular transport from endoplasmic reticulum to Golgi.By similarity

GO - Biological processi

Keywordsi

Biological processER-Golgi transport, Transport

Enzyme and pathway databases

ReactomeiR-MMU-204005 COPII-mediated vesicle transport
R-MMU-8876198 RAB GEFs exchange GTP for GDP on RABs

Names & Taxonomyi

Protein namesi
Recommended name:
Trafficking protein particle complex subunit 6B
Gene namesi
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 12

Organism-specific databases

MGIiMGI:1925482 Trappc6b

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Endoplasmic reticulum, Golgi apparatus

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002115881 – 158Trafficking protein particle complex subunit 6BAdd BLAST158

Proteomic databases

EPDiQ9D289
MaxQBiQ9D289
PaxDbiQ9D289
PeptideAtlasiQ9D289
PRIDEiQ9D289

PTM databases

iPTMnetiQ9D289
PhosphoSitePlusiQ9D289

Expressioni

Gene expression databases

BgeeiENSMUSG00000020993
CleanExiMM_TRAPPC6B
ExpressionAtlasiQ9D289 baseline and differential
GenevisibleiQ9D289 MM

Interactioni

Subunit structurei

Part of the multisubunit TRAPP (transport protein particle) complex. Homodimer. Heterodimer with TRAPPC3 (By similarity). Endoplasmic reticulum (By similarity).By similarity

Protein-protein interaction databases

IntActiQ9D289, 2 interactors
STRINGi10090.ENSMUSP00000021380

Structurei

3D structure databases

ProteinModelPortaliQ9D289
SMRiQ9D289
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiKOG3316 Eukaryota
ENOG410YUYH LUCA
GeneTreeiENSGT00390000012948
HOGENOMiHOG000200502
HOVERGENiHBG056159
InParanoidiQ9D289
KOiK20304
OMAiFLWFPCG
OrthoDBiEOG091G0MJ1
PhylomeDBiQ9D289
TreeFamiTF313010

Family and domain databases

CDDicd14944 TRAPPC6A_Trs33, 1 hit
InterProiView protein in InterPro
IPR024096 NO_sig/Golgi_transp_ligand-bd
IPR007194 TRAPP_component
IPR037992 TRAPPC6/Trs33
PANTHERiPTHR12817 PTHR12817, 1 hit
PfamiView protein in Pfam
PF04051 TRAPP, 1 hit
SUPFAMiSSF111126 SSF111126, 1 hit

Sequencei

Sequence statusi: Complete.

Q9D289-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MADEALFLLL HNEMVSGVYK SAEQGEVENG RCVTKLESMG FRVGQGLIER
60 70 80 90 100
FTKDTARFKD ELDIMKFICK DFWTTVFKKQ IDNLRTNHQG IYVLQDNKFR
110 120 130 140 150
LLIQLSAGKQ YLEHASKYLA FTCGLIRGGL SNLGIKSIVT AEVSSMPACK

FQVMIQKL
Length:158
Mass (Da):17,936
Last modified:June 1, 2001 - v1
Checksum:iDA7A047BC4807B9B
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK020026 mRNA Translation: BAB31972.1
AK089083 mRNA Translation: BAC40741.1
BC031464 mRNA Translation: AAH31464.1
CCDSiCCDS25932.1
RefSeqiNP_001293146.1, NM_001306217.1
NP_001293147.1, NM_001306218.1
NP_084333.1, NM_030057.3
UniGeneiMm.290070
Mm.414511

Genome annotation databases

EnsembliENSMUST00000021380; ENSMUSP00000021380; ENSMUSG00000020993
GeneIDi78232
KEGGimmu:78232
UCSCiuc007npy.1 mouse

Similar proteinsi

Entry informationi

Entry nameiTPC6B_MOUSE
AccessioniPrimary (citable) accession number: Q9D289
Entry historyiIntegrated into UniProtKB/Swiss-Prot: March 15, 2004
Last sequence update: June 1, 2001
Last modified: May 23, 2018
This is version 112 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
  2. SIMILARITY comments
    Index of protein domains and families

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