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Protein

Tetraspanin

Gene

Tspan2

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Biological processi

Names & Taxonomyi

Protein namesi
Recommended name:
TetraspaninUniRule annotation
Gene namesi
Name:Tspan2Imported
ORF Names:mCG_6403Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 3

Organism-specific databases

MGIiMGI:1917997 Tspan2

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei20 – 38HelicalUniRule annotationAdd BLAST19
Transmembranei50 – 71HelicalUniRule annotationAdd BLAST22
Transmembranei83 – 107HelicalUniRule annotationAdd BLAST25
Transmembranei184 – 210HelicalUniRule annotationAdd BLAST27

Keywords - Cellular componenti

Membrane

Expressioni

Gene expression databases

BgeeiENSMUSG00000027858

Family & Domainsi

Sequence similaritiesi

Belongs to the tetraspanin (TM4SF) family.UniRule annotationSAAS annotation

Keywords - Domaini

Transmembrane, Transmembrane helixUniRule annotationSAAS annotation

Phylogenomic databases

eggNOGiKOG3882 Eukaryota
ENOG4111IRY LUCA
GeneTreeiENSGT00880000137858
HOGENOMiHOG000230651
HOVERGENiHBG002324

Family and domain databases

Gene3Di1.10.1450.10, 1 hit
InterProiView protein in InterPro
IPR000301 Tetraspanin
IPR018499 Tetraspanin/Peripherin
IPR018503 Tetraspanin_CS
IPR008952 Tetraspanin_EC2_sf
PfamiView protein in Pfam
PF00335 Tetraspannin, 1 hit
PIRSFiPIRSF002419 Tetraspanin, 1 hit
PRINTSiPR00259 TMFOUR
SUPFAMiSSF48652 SSF48652, 1 hit
PROSITEiView protein in PROSITE
PS00421 TM4_1, 1 hit

Sequencei

Sequence statusi: Complete.

Q9D1X8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MLPRKKPSSS AASPGGWRQL AGSAVIAFGL WFRFGGTMKD LSSEDKSPEY
60 70 80 90 100
FYVGLYVLVG AGALMMTVGF FGCCGAMRES QCVLGSFFTC LLVIFAAEVT
110 120 130 140 150
TGVFAFIGKD VAIRHVQSMY EEAYSDYLKD RARGNGTLIT FHSAFQCCGK
160 170 180 190 200
ESSEQVQPTC PKELPGHKNC IDKIETVISA KLQLIGIVGI GIAGLTIFGM
210
IFSMVLCCAI RNSRDVI
Length:217
Mass (Da):23,448
Last modified:June 1, 2001 - v1
Checksum:iE18DB13DD73055CE
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC134871 Genomic DNA No translation available.
AK020982 mRNA Translation: BAB32269.1
CH466608 Genomic DNA Translation: EDL07612.1
RefSeqiNP_001230061.1, NM_001243132.1
UniGeneiMm.27469

Genome annotation databases

EnsembliENSMUST00000119902; ENSMUSP00000113803; ENSMUSG00000027858
GeneIDi70747
UCSCiuc029unw.1 mouse

Similar proteinsi

Entry informationi

Entry nameiQ9D1X8_MOUSE
AccessioniPrimary (citable) accession number: Q9D1X8
Entry historyiIntegrated into UniProtKB/TrEMBL: June 1, 2001
Last sequence update: June 1, 2001
Last modified: May 23, 2018
This is version 116 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

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