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Protein

60S ribosomal protein L34

Gene

Rpl34

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Ribonucleoprotein, Ribosomal protein

Enzyme and pathway databases

ReactomeiREACT_279505. Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC).
REACT_292264. GTP hydrolysis and joining of the 60S ribosomal subunit.
REACT_302277. Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC).
REACT_308559. Formation of a pool of free 40S subunits.
REACT_311765. Peptide chain elongation.
REACT_319670. Eukaryotic Translation Termination.
REACT_331340. SRP-dependent cotranslational protein targeting to membrane.
REACT_340387. L13a-mediated translational silencing of Ceruloplasmin expression.

Names & Taxonomyi

Protein namesi
Recommended name:
60S ribosomal protein L34
Gene namesi
Name:Rpl34
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
ProteomesiUP000000589 Componenti: Chromosome 3

Organism-specific databases

MGIiMGI:1915686. Rpl34.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Initiator methioninei1 – 11RemovedBy similarity
Chaini2 – 11711660S ribosomal protein L34PRO_0000131832Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei12 – 121PhosphoserineBy similarity
Modified residuei36 – 361N6-acetyllysineBy similarity
Modified residuei43 – 431N6-acetyllysine1 Publication

Keywords - PTMi

Acetylation, Phosphoprotein

Proteomic databases

MaxQBiQ9D1R9.
PaxDbiQ9D1R9.
PRIDEiQ9D1R9.

PTM databases

PhosphoSiteiQ9D1R9.

Expressioni

Gene expression databases

BgeeiQ9D1R9.
GenevestigatoriQ9D1R9.

Interactioni

Protein-protein interaction databases

BioGridi212853. 8 interactions.
546909. 8 interactions.
787025. 8 interactions.
IntActiQ9D1R9. 2 interactions.
MINTiMINT-1857602.

Structurei

3D structure databases

ProteinModelPortaliQ9D1R9.
SMRiQ9D1R9. Positions 2-115.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the ribosomal protein L34e family.Curated

Phylogenomic databases

eggNOGiCOG2174.
GeneTreeiENSGT00390000008294.
HOGENOMiHOG000216922.
HOVERGENiHBG024280.
InParanoidiQ9D1R9.
KOiK02915.
OMAiRCGDCVK.
OrthoDBiEOG7QC7Z7.
PhylomeDBiQ9D1R9.
TreeFamiTF314326.

Family and domain databases

InterProiIPR008195. Ribosomal_L34Ae.
IPR018065. Ribosomal_L34e_CS.
[Graphical view]
PANTHERiPTHR10759. PTHR10759. 1 hit.
PfamiPF01199. Ribosomal_L34e. 1 hit.
[Graphical view]
PRINTSiPR01250. RIBOSOMALL34.
PROSITEiPS01145. RIBOSOMAL_L34E. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q9D1R9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MVQRLTYRRR LSYNTASNKT RLSRTPGNRI VYLYTKKVGK APKSACGVCP
60 70 80 90 100
GRLRGVRAVR PKVLMRLSKT QKHVSRAYGG SMCAKCVRDR IKRAFLIEEQ
110
KIVVKVLKAQ AQSQKAK
Length:117
Mass (Da):13,293
Last modified:January 23, 2007 - v2
Checksum:i6775B00B98CB6A30
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK003177 mRNA. Translation: BAB22621.1.
AK146252 mRNA. Translation: BAE27014.1.
CH466532 Genomic DNA. Translation: EDL12210.1.
CH466532 Genomic DNA. Translation: EDL12212.1.
BC028517 mRNA. Translation: AAH28517.1.
BC058118 mRNA. Translation: AAH58118.1.
BC100360 mRNA. Translation: AAI00361.1.
CCDSiCCDS17841.1.
RefSeqiNP_001005859.1. NM_001005859.3.
NP_001186279.1. NM_001199350.1.
NP_001274510.1. NM_001287581.1.
NP_081000.1. NM_026724.2.
XP_001481222.1. XM_001481172.5.
UniGeneiMm.140568.
Mm.391636.

Genome annotation databases

EnsembliENSMUST00000062601; ENSMUSP00000086614; ENSMUSG00000062006.
ENSMUST00000079085; ENSMUSP00000078092; ENSMUSG00000062006.
GeneIDi100043876.
619547.
68436.
KEGGimmu:100043876.
mmu:619547.
mmu:68436.
UCSCiuc008rjd.1. mouse.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK003177 mRNA. Translation: BAB22621.1.
AK146252 mRNA. Translation: BAE27014.1.
CH466532 Genomic DNA. Translation: EDL12210.1.
CH466532 Genomic DNA. Translation: EDL12212.1.
BC028517 mRNA. Translation: AAH28517.1.
BC058118 mRNA. Translation: AAH58118.1.
BC100360 mRNA. Translation: AAI00361.1.
CCDSiCCDS17841.1.
RefSeqiNP_001005859.1. NM_001005859.3.
NP_001186279.1. NM_001199350.1.
NP_001274510.1. NM_001287581.1.
NP_081000.1. NM_026724.2.
XP_001481222.1. XM_001481172.5.
UniGeneiMm.140568.
Mm.391636.

3D structure databases

ProteinModelPortaliQ9D1R9.
SMRiQ9D1R9. Positions 2-115.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi212853. 8 interactions.
546909. 8 interactions.
787025. 8 interactions.
IntActiQ9D1R9. 2 interactions.
MINTiMINT-1857602.

PTM databases

PhosphoSiteiQ9D1R9.

Proteomic databases

MaxQBiQ9D1R9.
PaxDbiQ9D1R9.
PRIDEiQ9D1R9.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000062601; ENSMUSP00000086614; ENSMUSG00000062006.
ENSMUST00000079085; ENSMUSP00000078092; ENSMUSG00000062006.
GeneIDi100043876.
619547.
68436.
KEGGimmu:100043876.
mmu:619547.
mmu:68436.
UCSCiuc008rjd.1. mouse.

Organism-specific databases

CTDi6164.
619547.
MGIiMGI:1915686. Rpl34.

Phylogenomic databases

eggNOGiCOG2174.
GeneTreeiENSGT00390000008294.
HOGENOMiHOG000216922.
HOVERGENiHBG024280.
InParanoidiQ9D1R9.
KOiK02915.
OMAiRCGDCVK.
OrthoDBiEOG7QC7Z7.
PhylomeDBiQ9D1R9.
TreeFamiTF314326.

Enzyme and pathway databases

ReactomeiREACT_279505. Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC).
REACT_292264. GTP hydrolysis and joining of the 60S ribosomal subunit.
REACT_302277. Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC).
REACT_308559. Formation of a pool of free 40S subunits.
REACT_311765. Peptide chain elongation.
REACT_319670. Eukaryotic Translation Termination.
REACT_331340. SRP-dependent cotranslational protein targeting to membrane.
REACT_340387. L13a-mediated translational silencing of Ceruloplasmin expression.

Miscellaneous databases

NextBioi327176.
PROiQ9D1R9.
SOURCEiSearch...

Gene expression databases

BgeeiQ9D1R9.
GenevestigatoriQ9D1R9.

Family and domain databases

InterProiIPR008195. Ribosomal_L34Ae.
IPR018065. Ribosomal_L34e_CS.
[Graphical view]
PANTHERiPTHR10759. PTHR10759. 1 hit.
PfamiPF01199. Ribosomal_L34e. 1 hit.
[Graphical view]
PRINTSiPR01250. RIBOSOMALL34.
PROSITEiPS01145. RIBOSOMAL_L34E. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "The transcriptional landscape of the mammalian genome."
    Carninci P., Kasukawa T., Katayama S., Gough J., Frith M.C., Maeda N., Oyama R., Ravasi T., Lenhard B., Wells C., Kodzius R., Shimokawa K., Bajic V.B., Brenner S.E., Batalov S., Forrest A.R., Zavolan M., Davis M.J.
    , Wilming L.G., Aidinis V., Allen J.E., Ambesi-Impiombato A., Apweiler R., Aturaliya R.N., Bailey T.L., Bansal M., Baxter L., Beisel K.W., Bersano T., Bono H., Chalk A.M., Chiu K.P., Choudhary V., Christoffels A., Clutterbuck D.R., Crowe M.L., Dalla E., Dalrymple B.P., de Bono B., Della Gatta G., di Bernardo D., Down T., Engstrom P., Fagiolini M., Faulkner G., Fletcher C.F., Fukushima T., Furuno M., Futaki S., Gariboldi M., Georgii-Hemming P., Gingeras T.R., Gojobori T., Green R.E., Gustincich S., Harbers M., Hayashi Y., Hensch T.K., Hirokawa N., Hill D., Huminiecki L., Iacono M., Ikeo K., Iwama A., Ishikawa T., Jakt M., Kanapin A., Katoh M., Kawasawa Y., Kelso J., Kitamura H., Kitano H., Kollias G., Krishnan S.P., Kruger A., Kummerfeld S.K., Kurochkin I.V., Lareau L.F., Lazarevic D., Lipovich L., Liu J., Liuni S., McWilliam S., Madan Babu M., Madera M., Marchionni L., Matsuda H., Matsuzawa S., Miki H., Mignone F., Miyake S., Morris K., Mottagui-Tabar S., Mulder N., Nakano N., Nakauchi H., Ng P., Nilsson R., Nishiguchi S., Nishikawa S., Nori F., Ohara O., Okazaki Y., Orlando V., Pang K.C., Pavan W.J., Pavesi G., Pesole G., Petrovsky N., Piazza S., Reed J., Reid J.F., Ring B.Z., Ringwald M., Rost B., Ruan Y., Salzberg S.L., Sandelin A., Schneider C., Schoenbach C., Sekiguchi K., Semple C.A., Seno S., Sessa L., Sheng Y., Shibata Y., Shimada H., Shimada K., Silva D., Sinclair B., Sperling S., Stupka E., Sugiura K., Sultana R., Takenaka Y., Taki K., Tammoja K., Tan S.L., Tang S., Taylor M.S., Tegner J., Teichmann S.A., Ueda H.R., van Nimwegen E., Verardo R., Wei C.L., Yagi K., Yamanishi H., Zabarovsky E., Zhu S., Zimmer A., Hide W., Bult C., Grimmond S.M., Teasdale R.D., Liu E.T., Brusic V., Quackenbush J., Wahlestedt C., Mattick J.S., Hume D.A., Kai C., Sasaki D., Tomaru Y., Fukuda S., Kanamori-Katayama M., Suzuki M., Aoki J., Arakawa T., Iida J., Imamura K., Itoh M., Kato T., Kawaji H., Kawagashira N., Kawashima T., Kojima M., Kondo S., Konno H., Nakano K., Ninomiya N., Nishio T., Okada M., Plessy C., Shibata K., Shiraki T., Suzuki S., Tagami M., Waki K., Watahiki A., Okamura-Oho Y., Suzuki H., Kawai J., Hayashizaki Y.
    Science 309:1559-1563(2005) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Strain: BALB/c and C57BL/6J.
    Tissue: Embryo.
  2. Mural R.J., Adams M.D., Myers E.W., Smith H.O., Venter J.C.
    Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
  3. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Strain: C57BL/6.
    Tissue: Brain, Mammary gland and Thyroid.
  4. "SIRT5-mediated lysine desuccinylation impacts diverse metabolic pathways."
    Park J., Chen Y., Tishkoff D.X., Peng C., Tan M., Dai L., Xie Z., Zhang Y., Zwaans B.M., Skinner M.E., Lombard D.B., Zhao Y.
    Mol. Cell 50:919-930(2013) [PubMed] [Europe PMC] [Abstract]
    Cited for: ACETYLATION [LARGE SCALE ANALYSIS] AT LYS-43, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
    Tissue: Embryonic fibroblast.

Entry informationi

Entry nameiRL34_MOUSE
AccessioniPrimary (citable) accession number: Q9D1R9
Secondary accession number(s): Q497V4
Entry historyi
Integrated into UniProtKB/Swiss-Prot: April 27, 2001
Last sequence update: January 23, 2007
Last modified: April 1, 2015
This is version 102 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
  2. Ribosomal proteins
    Ribosomal proteins families and list of entries
  3. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.