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Q9D1Q4 (DPM3_MOUSE) Reviewed, UniProtKB/Swiss-Prot

Last modified April 3, 2013. Version 73. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Dolichol-phosphate mannosyltransferase subunit 3
Alternative name(s):
DPM synthase complex subunit 3
Dolichol-phosphate mannose synthase subunit 3
Dolichyl-phosphate beta-D-mannosyltransferase subunit 3
Mannose-P-dolichol synthase subunit 3
Short name=MPD synthase subunit 3
Gene names
Name:Dpm3
OrganismMus musculus (Mouse) [Reference proteome]
Taxonomic identifier10090 [NCBI]
Taxonomic lineageEukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Glires › Rodentia › Sciurognathi › Muroidea › Muridae › Murinae › Mus › Mus

Protein attributes

Sequence length92 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Stabilizer subunit of the dolichol-phosphate-mannose synthase complex By similarity.

Subunit structure

Composed of three subunits; DPM1, DPM2 and DPM3. Associated with DPM1 via its C-terminal domain and with DPM2 via its N-terminal portion By similarity.

Subcellular location

Endoplasmic reticulum membrane; Multi-pass membrane protein By similarity.

Sequence similarities

Belongs to the DPM3 family.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 9292Dolichol-phosphate mannosyltransferase subunit 3
PRO_0000195001

Regions

Transmembrane8 – 2821Helical; Potential
Transmembrane37 – 5721Helical; Potential

Sequences

Sequence LengthMass (Da)Tools
Q9D1Q4 [UniParc].

Last modified June 1, 2001. Version 1.
Checksum: B621E6E47337CC40

FASTA9210,139
        10         20         30         40         50         60 
MTKLTQWLWG LALLGSAWAA LTMGALGLEL PFPCREVLWP LPAYLLVSAG CYALGTVGYR 

        70         80         90 
VATFHDCEDA ARELQSQIVE ARADLARRGL RF

« Hide

References

[1]"The transcriptional landscape of the mammalian genome."
Carninci P., Kasukawa T., Katayama S., Gough J., Frith M.C., Maeda N., Oyama R., Ravasi T., Lenhard B., Wells C., Kodzius R., Shimokawa K., Bajic V.B., Brenner S.E., Batalov S., Forrest A.R., Zavolan M., Davis M.J. expand/collapse author list , Wilming L.G., Aidinis V., Allen J.E., Ambesi-Impiombato A., Apweiler R., Aturaliya R.N., Bailey T.L., Bansal M., Baxter L., Beisel K.W., Bersano T., Bono H., Chalk A.M., Chiu K.P., Choudhary V., Christoffels A., Clutterbuck D.R., Crowe M.L., Dalla E., Dalrymple B.P., de Bono B., Della Gatta G., di Bernardo D., Down T., Engstrom P., Fagiolini M., Faulkner G., Fletcher C.F., Fukushima T., Furuno M., Futaki S., Gariboldi M., Georgii-Hemming P., Gingeras T.R., Gojobori T., Green R.E., Gustincich S., Harbers M., Hayashi Y., Hensch T.K., Hirokawa N., Hill D., Huminiecki L., Iacono M., Ikeo K., Iwama A., Ishikawa T., Jakt M., Kanapin A., Katoh M., Kawasawa Y., Kelso J., Kitamura H., Kitano H., Kollias G., Krishnan S.P., Kruger A., Kummerfeld S.K., Kurochkin I.V., Lareau L.F., Lazarevic D., Lipovich L., Liu J., Liuni S., McWilliam S., Madan Babu M., Madera M., Marchionni L., Matsuda H., Matsuzawa S., Miki H., Mignone F., Miyake S., Morris K., Mottagui-Tabar S., Mulder N., Nakano N., Nakauchi H., Ng P., Nilsson R., Nishiguchi S., Nishikawa S., Nori F., Ohara O., Okazaki Y., Orlando V., Pang K.C., Pavan W.J., Pavesi G., Pesole G., Petrovsky N., Piazza S., Reed J., Reid J.F., Ring B.Z., Ringwald M., Rost B., Ruan Y., Salzberg S.L., Sandelin A., Schneider C., Schoenbach C., Sekiguchi K., Semple C.A., Seno S., Sessa L., Sheng Y., Shibata Y., Shimada H., Shimada K., Silva D., Sinclair B., Sperling S., Stupka E., Sugiura K., Sultana R., Takenaka Y., Taki K., Tammoja K., Tan S.L., Tang S., Taylor M.S., Tegner J., Teichmann S.A., Ueda H.R., van Nimwegen E., Verardo R., Wei C.L., Yagi K., Yamanishi H., Zabarovsky E., Zhu S., Zimmer A., Hide W., Bult C., Grimmond S.M., Teasdale R.D., Liu E.T., Brusic V., Quackenbush J., Wahlestedt C., Mattick J.S., Hume D.A., Kai C., Sasaki D., Tomaru Y., Fukuda S., Kanamori-Katayama M., Suzuki M., Aoki J., Arakawa T., Iida J., Imamura K., Itoh M., Kato T., Kawaji H., Kawagashira N., Kawashima T., Kojima M., Kondo S., Konno H., Nakano K., Ninomiya N., Nishio T., Okada M., Plessy C., Shibata K., Shiraki T., Suzuki S., Tagami M., Waki K., Watahiki A., Okamura-Oho Y., Suzuki H., Kawai J., Hayashizaki Y.
Science 309:1559-1563(2005) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
Strain: C57BL/6J.
Tissue: Embryo.
[2]"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
Tissue: Mammary gland.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		AK003223 mRNA. Translation: BAB22652.1.
BC037761 mRNA. No translation available.
IPIIPI00134053.
RefSeqNP_081043.1. NM_026767.3.
UniGeneMm.272927.

3D structure databases

ModBaseSearch...

Protein-protein interaction databases

STRING10090.ENSMUSP00000103086.

Proteomic databases

PaxDbQ9D1Q4.
PRIDEQ9D1Q4.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblENSMUST00000040824; ENSMUSP00000040860; ENSMUSG00000042737.
ENSMUST00000107462; ENSMUSP00000103086; ENSMUSG00000042737.
GeneID68563.
KEGGmmu:68563.
UCSCuc008pym.1. mouse.

Organism-specific databases

CTD54344.
MGIMGI:1915813. Dpm3.

Phylogenomic databases

eggNOGNOG145469.
GeneTreeENSGT00390000008892.
HOGENOMHOG000038272.
HOVERGENHBG018968.
InParanoidQ9D1Q4.
KOK09659.
OMAFGCYSLA.
OrthoDBEOG4V4399.

Gene expression databases

BgeeQ9D1Q4.
GenevestigatorQ9D1Q4.
GermOnlineENSMUSG00000042737. Mus musculus.

Family and domain databases

InterProIPR013174. DPM3.
[Graphical view]
PfamPF08285. DPM3. 1 hit.
[Graphical view]
ProtoNetSearch...

Other

NextBio327458.
SOURCESearch...

Entry information

Entry nameDPM3_MOUSE
AccessionPrimary (citable) accession number: Q9D1Q4
Entry history
Integrated into UniProtKB/Swiss-Prot: January 23, 2002
Last sequence update: June 1, 2001
Last modified: April 3, 2013
This is version 73 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Relevant documents

MGD cross-references

Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot

SIMILARITY comments

Index of protein domains and families

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