Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

Q9D1Q4

- DPM3_MOUSE

UniProt

Q9D1Q4 - DPM3_MOUSE

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein

Dolichol-phosphate mannosyltransferase subunit 3

Gene

Dpm3

Organism
Mus musculus (Mouse)
Status
Reviewed - Annotation score: 3 out of 5- Protein inferred from homologyi

Functioni

Stabilizer subunit of the dolichol-phosphate mannose (DPM) synthase complex; tethers catalytic subunit DPM1 to the ER.By similarity

Pathwayi

GO - Molecular functioni

  1. dolichyl-phosphate beta-D-mannosyltransferase activity Source: Ensembl

GO - Biological processi

  1. GPI anchor biosynthetic process Source: Ensembl
  2. mannosylation Source: GOC
  3. protein glycosylation Source: UniProtKB-UniPathway
  4. regulation of protein stability Source: Ensembl
Complete GO annotation...

Enzyme and pathway databases

UniPathwayiUPA00378.

Names & Taxonomyi

Protein namesi
Recommended name:
Dolichol-phosphate mannosyltransferase subunit 3
Alternative name(s):
Dolichol-phosphate mannose synthase subunit 3
Short name:
DPM synthase subunit 3
Dolichyl-phosphate beta-D-mannosyltransferase subunit 3
Mannose-P-dolichol synthase subunit 3
Short name:
MPD synthase subunit 3
Gene namesi
Name:Dpm3
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
ProteomesiUP000000589: Chromosome 3

Organism-specific databases

MGIiMGI:1915813. Dpm3.

Subcellular locationi

GO - Cellular componenti

  1. dolichol-phosphate-mannose synthase complex Source: HGNC
  2. integral component of endoplasmic reticulum membrane Source: HGNC
Complete GO annotation...

Keywords - Cellular componenti

Endoplasmic reticulum, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 9292Dolichol-phosphate mannosyltransferase subunit 3PRO_0000195001Add
BLAST

Proteomic databases

MaxQBiQ9D1Q4.
PaxDbiQ9D1Q4.
PRIDEiQ9D1Q4.

Expressioni

Gene expression databases

BgeeiQ9D1Q4.
GenevestigatoriQ9D1Q4.

Interactioni

Subunit structurei

Component of the dolichol-phosphate mannose (DPM) synthase complex composed of DPM1, DPM2 and DPM3; in the complex associated with DPM1 via its C-terminal domain and with DPM2 via its N-terminal portion.By similarity

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000103086.

Structurei

Transmembrane

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei8 – 2821HelicalSequence AnalysisAdd
BLAST
Transmembranei37 – 5721HelicalSequence AnalysisAdd
BLAST

Family & Domainsi

Sequence similaritiesi

Belongs to the DPM3 family.Curated

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiNOG145469.
GeneTreeiENSGT00390000008892.
HOGENOMiHOG000038272.
HOVERGENiHBG018968.
InParanoidiQ9D1Q4.
KOiK09659.
OMAiYREVAWP.
OrthoDBiEOG73540R.
PhylomeDBiQ9D1Q4.
TreeFamiTF300274.

Family and domain databases

InterProiIPR013174. DPM3.
[Graphical view]
PfamiPF08285. DPM3. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q9D1Q4-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MTKLTQWLWG LALLGSAWAA LTMGALGLEL PFPCREVLWP LPAYLLVSAG
60 70 80 90
CYALGTVGYR VATFHDCEDA ARELQSQIVE ARADLARRGL RF
Length:92
Mass (Da):10,139
Last modified:June 1, 2001 - v1
Checksum:iB621E6E47337CC40
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AK003223 mRNA. Translation: BAB22652.1.
BC037761 mRNA. No translation available.
CCDSiCCDS38487.1.
RefSeqiNP_081043.1. NM_026767.4.
XP_006502046.1. XM_006501983.1.
UniGeneiMm.272927.

Genome annotation databases

EnsembliENSMUST00000040824; ENSMUSP00000040860; ENSMUSG00000042737.
ENSMUST00000107462; ENSMUSP00000103086; ENSMUSG00000042737.
GeneIDi68563.
KEGGimmu:68563.
UCSCiuc008pym.1. mouse.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AK003223 mRNA. Translation: BAB22652.1 .
BC037761 mRNA. No translation available.
CCDSi CCDS38487.1.
RefSeqi NP_081043.1. NM_026767.4.
XP_006502046.1. XM_006501983.1.
UniGenei Mm.272927.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 10090.ENSMUSP00000103086.

Proteomic databases

MaxQBi Q9D1Q4.
PaxDbi Q9D1Q4.
PRIDEi Q9D1Q4.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENSMUST00000040824 ; ENSMUSP00000040860 ; ENSMUSG00000042737 .
ENSMUST00000107462 ; ENSMUSP00000103086 ; ENSMUSG00000042737 .
GeneIDi 68563.
KEGGi mmu:68563.
UCSCi uc008pym.1. mouse.

Organism-specific databases

CTDi 54344.
MGIi MGI:1915813. Dpm3.

Phylogenomic databases

eggNOGi NOG145469.
GeneTreei ENSGT00390000008892.
HOGENOMi HOG000038272.
HOVERGENi HBG018968.
InParanoidi Q9D1Q4.
KOi K09659.
OMAi YREVAWP.
OrthoDBi EOG73540R.
PhylomeDBi Q9D1Q4.
TreeFami TF300274.

Enzyme and pathway databases

UniPathwayi UPA00378 .

Miscellaneous databases

NextBioi 327458.
PROi Q9D1Q4.
SOURCEi Search...

Gene expression databases

Bgeei Q9D1Q4.
Genevestigatori Q9D1Q4.

Family and domain databases

InterProi IPR013174. DPM3.
[Graphical view ]
Pfami PF08285. DPM3. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "The transcriptional landscape of the mammalian genome."
    Carninci P., Kasukawa T., Katayama S., Gough J., Frith M.C., Maeda N., Oyama R., Ravasi T., Lenhard B., Wells C., Kodzius R., Shimokawa K., Bajic V.B., Brenner S.E., Batalov S., Forrest A.R., Zavolan M., Davis M.J.
    , Wilming L.G., Aidinis V., Allen J.E., Ambesi-Impiombato A., Apweiler R., Aturaliya R.N., Bailey T.L., Bansal M., Baxter L., Beisel K.W., Bersano T., Bono H., Chalk A.M., Chiu K.P., Choudhary V., Christoffels A., Clutterbuck D.R., Crowe M.L., Dalla E., Dalrymple B.P., de Bono B., Della Gatta G., di Bernardo D., Down T., Engstrom P., Fagiolini M., Faulkner G., Fletcher C.F., Fukushima T., Furuno M., Futaki S., Gariboldi M., Georgii-Hemming P., Gingeras T.R., Gojobori T., Green R.E., Gustincich S., Harbers M., Hayashi Y., Hensch T.K., Hirokawa N., Hill D., Huminiecki L., Iacono M., Ikeo K., Iwama A., Ishikawa T., Jakt M., Kanapin A., Katoh M., Kawasawa Y., Kelso J., Kitamura H., Kitano H., Kollias G., Krishnan S.P., Kruger A., Kummerfeld S.K., Kurochkin I.V., Lareau L.F., Lazarevic D., Lipovich L., Liu J., Liuni S., McWilliam S., Madan Babu M., Madera M., Marchionni L., Matsuda H., Matsuzawa S., Miki H., Mignone F., Miyake S., Morris K., Mottagui-Tabar S., Mulder N., Nakano N., Nakauchi H., Ng P., Nilsson R., Nishiguchi S., Nishikawa S., Nori F., Ohara O., Okazaki Y., Orlando V., Pang K.C., Pavan W.J., Pavesi G., Pesole G., Petrovsky N., Piazza S., Reed J., Reid J.F., Ring B.Z., Ringwald M., Rost B., Ruan Y., Salzberg S.L., Sandelin A., Schneider C., Schoenbach C., Sekiguchi K., Semple C.A., Seno S., Sessa L., Sheng Y., Shibata Y., Shimada H., Shimada K., Silva D., Sinclair B., Sperling S., Stupka E., Sugiura K., Sultana R., Takenaka Y., Taki K., Tammoja K., Tan S.L., Tang S., Taylor M.S., Tegner J., Teichmann S.A., Ueda H.R., van Nimwegen E., Verardo R., Wei C.L., Yagi K., Yamanishi H., Zabarovsky E., Zhu S., Zimmer A., Hide W., Bult C., Grimmond S.M., Teasdale R.D., Liu E.T., Brusic V., Quackenbush J., Wahlestedt C., Mattick J.S., Hume D.A., Kai C., Sasaki D., Tomaru Y., Fukuda S., Kanamori-Katayama M., Suzuki M., Aoki J., Arakawa T., Iida J., Imamura K., Itoh M., Kato T., Kawaji H., Kawagashira N., Kawashima T., Kojima M., Kondo S., Konno H., Nakano K., Ninomiya N., Nishio T., Okada M., Plessy C., Shibata K., Shiraki T., Suzuki S., Tagami M., Waki K., Watahiki A., Okamura-Oho Y., Suzuki H., Kawai J., Hayashizaki Y.
    Science 309:1559-1563(2005) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Strain: C57BL/6J.
    Tissue: Embryo.
  2. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Tissue: Mammary gland.

Entry informationi

Entry nameiDPM3_MOUSE
AccessioniPrimary (citable) accession number: Q9D1Q4
Entry historyi
Integrated into UniProtKB/Swiss-Prot: January 23, 2002
Last sequence update: June 1, 2001
Last modified: October 29, 2014
This is version 84 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
  2. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  3. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3