Reviewed, UniProtKB/Swiss-Prot Q9D1H7 (CG020_MOUSE)

Names and origin

Protein names	Recommended name:     UPF0363 protein C7orf20 homolog
Organism	Mus musculus (Mouse)
Taxonomic identifier	10090 [NCBI]
Taxonomic lineage	Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Glires › Rodentia › Sciurognathi › Muroidea › Muridae › Murinae › Mus

Protein attributes

Sequence length	327 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is further processed into a mature form.
Protein existence	Evidence at transcript level.

General annotation (Comments)

Sequence similarities

Belongs to the UPF0363 family.

Ontologies

Keywords
Coding sequence diversity	Alternative splicing
PTM	Acetylation
Gene Ontology (GO)
None. [Check GOA]

Alternative products

This entry describes 2 isoforms produced by alternative splicing. [Align] [Select]

Isoform 1 (identifier: Q9D1H7-1)

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

Note: No experimental confirmation available.

Isoform 2 (identifier: Q9D1H7-2)

The sequence of this isoform differs from the canonical sequence as follows:
     1-53: Missing.

Note: No experimental confirmation available.

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Initiator methionine	1	1	Removed By similarity
	Chain	2 – 327	326	UPF0363 protein C7orf20 homolog		PRO_0000228105
Amino acid modifications
	Modified residue	2	1	N-acetylalanine By similarity
Natural variations
	Alternative sequence	1 – 53	53	Missing in isoform 2.		VSP_017653

Sequences

	Sequence		Length	Mass (Da)
	Isoform 1 [UniParc]. Last modified July 5, 2004. Version 2. Checksum: 04B8DCC8E75FB022	FASTA	327	36,525
	10 20 30 40 50 60 MAAAAAMAEQ EGARNGARNR GGVQRVEGKL RASVEKGDYY EAHQMYRTLF FRYMSQSKHA 70 80 90 100 110 120 EARELMYSGA LLFFSHGQQN SAADLSMLVL ESLEKAEVDV ADELLENLAK VFSLMDPNSP 130 140 150 160 170 180 ERVAFVSRAL KWSSGGSGKL GHPRLHQLLA LTLWKEQNYC ESRYHFLHSS DGEGCANMLV 190 200 210 220 230 240 EYSTARGFRS EVDMFVAQAV LQFLCLKNKN SALVVFTTYT QKHPSIEDGP PFVQPLLNFI 250 260 270 280 290 300 WFLLLAVDGG KLAVFTVLCE QYQPSLRRDP MYNEYLDRIG QLFFGVPPKQ TSSYGGLLGN 310 320 LLSSLMGSSE QEEGEESQDD SSPIELD
	Isoform 2. Checksum: 185B7840B12D0698	FASTA	274	30,560
	10 20 30 40 50 60 MSQSKHAEAR ELMYSGALLF FSHGQQNSAA DLSMLVLESL EKAEVDVADE LLENLAKVFS 70 80 90 100 110 120 LMDPNSPERV AFVSRALKWS SGGSGKLGHP RLHQLLALTL WKEQNYCESR YHFLHSSDGE 130 140 150 160 170 180 GCANMLVEYS TARGFRSEVD MFVAQAVLQF LCLKNKNSAL VVFTTYTQKH PSIEDGPPFV 190 200 210 220 230 240 QPLLNFIWFL LLAVDGGKLA VFTVLCEQYQ PSLRRDPMYN EYLDRIGQLF FGVPPKQTSS 250 260 270 YGGLLGNLLS SLMGSSEQEE GEESQDDSSP IELD

References

[1]	"The transcriptional landscape of the mammalian genome." Carninci P., Kasukawa T., Katayama S., Gough J., Frith M.C., Maeda N., Oyama R., Ravasi T., Lenhard B., Wells C., Kodzius R., Shimokawa K., Bajic V.B., Brenner S.E., Batalov S., Forrest A.R., Zavolan M., Davis M.J. , Wilming L.G., Aidinis V., Allen J.E., Ambesi-Impiombato A., Apweiler R., Aturaliya R.N., Bailey T.L., Bansal M., Baxter L., Beisel K.W., Bersano T., Bono H., Chalk A.M., Chiu K.P., Choudhary V., Christoffels A., Clutterbuck D.R., Crowe M.L., Dalla E., Dalrymple B.P., de Bono B., Della Gatta G., di Bernardo D., Down T., Engstrom P., Fagiolini M., Faulkner G., Fletcher C.F., Fukushima T., Furuno M., Futaki S., Gariboldi M., Georgii-Hemming P., Gingeras T.R., Gojobori T., Green R.E., Gustincich S., Harbers M., Hayashi Y., Hensch T.K., Hirokawa N., Hill D., Huminiecki L., Iacono M., Ikeo K., Iwama A., Ishikawa T., Jakt M., Kanapin A., Katoh M., Kawasawa Y., Kelso J., Kitamura H., Kitano H., Kollias G., Krishnan S.P., Kruger A., Kummerfeld S.K., Kurochkin I.V., Lareau L.F., Lazarevic D., Lipovich L., Liu J., Liuni S., McWilliam S., Madan Babu M., Madera M., Marchionni L., Matsuda H., Matsuzawa S., Miki H., Mignone F., Miyake S., Morris K., Mottagui-Tabar S., Mulder N., Nakano N., Nakauchi H., Ng P., Nilsson R., Nishiguchi S., Nishikawa S., Nori F., Ohara O., Okazaki Y., Orlando V., Pang K.C., Pavan W.J., Pavesi G., Pesole G., Petrovsky N., Piazza S., Reed J., Reid J.F., Ring B.Z., Ringwald M., Rost B., Ruan Y., Salzberg S.L., Sandelin A., Schneider C., Schoenbach C., Sekiguchi K., Semple C.A., Seno S., Sessa L., Sheng Y., Shibata Y., Shimada H., Shimada K., Silva D., Sinclair B., Sperling S., Stupka E., Sugiura K., Sultana R., Takenaka Y., Taki K., Tammoja K., Tan S.L., Tang S., Taylor M.S., Tegner J., Teichmann S.A., Ueda H.R., van Nimwegen E., Verardo R., Wei C.L., Yagi K., Yamanishi H., Zabarovsky E., Zhu S., Zimmer A., Hide W., Bult C., Grimmond S.M., Teasdale R.D., Liu E.T., Brusic V., Quackenbush J., Wahlestedt C., Mattick J.S., Hume D.A., Kai C., Sasaki D., Tomaru Y., Fukuda S., Kanamori-Katayama M., Suzuki M., Aoki J., Arakawa T., Iida J., Imamura K., Itoh M., Kato T., Kawaji H., Kawagashira N., Kawashima T., Kojima M., Kondo S., Konno H., Nakano K., Ninomiya N., Nishio T., Okada M., Plessy C., Shibata K., Shiraki T., Suzuki S., Tagami M., Waki K., Watahiki A., Okamura-Oho Y., Suzuki H., Kawai J., Hayashizaki Y. Science 309:1559-1563(2005) [PubMed: 16141072] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1). Strain: C57BL/6J. Tissue: Embryo.
[2]	"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)." The MGC Project Team Genome Res. 14:2121-2127(2004) [PubMed: 15489334] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2). Strain: FVB/N. Tissue: Liver.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBLGenBankDDBJ	AK003551 mRNA. Translation: BAB22851.2. BC019557 mRNA. Translation: AAH19557.1.
IPI	IPI00272521. IPI00742325.
RefSeq	NP_001156788.1. NP_080545.2.
UniGene	Mm.270137
3D structure databases
ModBase	Search...
Proteomic databases
PRIDE	Q9D1H7.
Genome annotation databases
Ensembl	ENSMUST00000026976; ENSMUSP00000026976; ENSMUSG00000025858; Mus musculus. [Genome view]
GeneID	67604.
KEGG	mmu:67604.
NMPDR	fig|10090.3.peg.12689.
UCSC	uc009agg.1. mouse. uc009agh.1. mouse.
Organism-specific databases
MGI	MGI:1914854. 1110007L15Rik.
Phylogenomic databases
HOGENOM	Q9D1H7.
HOVERGEN	Q9D1H7.
OMA	YGGLLGN
OrthoDB	EOG9Q87H0
Gene expression databases
ArrayExpress	Q9D1H7.
Bgee	Q9D1H7.
CleanEx	MM_1110007L15RIK.
Genevestigator	Q9D1H7.
GermOnline	ENSMUSG00000025858. Mus musculus.
Family and domain databases
InterPro	IPR007317. UPF0363. [Graphical view]
PANTHER	PTHR12875. DUF410. 1 hit.
Pfam	PF04190. DUF410. 1 hit. [Graphical view]
ProtoNet	Search...
Other Resources
NextBio	325021.

Entry information

Entry name

CG020_MOUSE

Accession

Primary (citable) accession number: Q9D1H7
Secondary accession number(s): Q78J86

Entry history

Integrated into UniProtKB/Swiss-Prot:	March 21, 2006
Last sequence update:	July 5, 2004
Last modified:	November 24, 2009
This is version 55 of the entry and version 2 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HPI (Human Proteome Initiative)