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Protein
Submitted name:

Solute carrier family 37 (Glucose-6-phosphate transporter), member 4

Gene

Slc37a4

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

  • cellular calcium ion homeostasis Source: MGI
  • cholesterol homeostasis Source: MGI
  • cytokine production Source: MGI
  • glucose-6-phosphate transport Source: MGI
  • glucose homeostasis Source: MGI
  • glycogen metabolic process Source: MGI
  • lactate metabolic process Source: MGI
  • myeloid progenitor cell differentiation Source: MGI
  • negative regulation of chemokine production Source: MGI
  • neutrophil chemotaxis Source: MGI
  • neutrophil homeostasis Source: MGI
  • phosphate ion transmembrane transport Source: MGI
  • positive regulation of catalytic activity Source: MGI
  • post-embryonic hemopoiesis Source: MGI
  • respiratory burst Source: MGI
  • response to glucose Source: Ensembl
  • response to nutrient Source: Ensembl
  • response to organic cyclic compound Source: Ensembl
  • steroid metabolic process Source: MGI
  • triglyceride metabolic process Source: MGI

Names & Taxonomyi

Protein namesi
Submitted name:
Solute carrier family 37 (Glucose-6-phosphate transporter), member 4Imported
Submitted name:
Solute carrier family 37 (Glycerol-6-phosphate transporter), member 4Imported
Gene namesi
Name:Slc37a4Imported
ORF Names:mCG_10718Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 9

Organism-specific databases

MGIiMGI:1316650 Slc37a4

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei6 – 26HelicalSequence analysisAdd BLAST21
Transmembranei84 – 109HelicalSequence analysisAdd BLAST26
Transmembranei137 – 160HelicalSequence analysisAdd BLAST24
Transmembranei167 – 187HelicalSequence analysisAdd BLAST21
Transmembranei225 – 247HelicalSequence analysisAdd BLAST23
Transmembranei259 – 283HelicalSequence analysisAdd BLAST25
Transmembranei303 – 322HelicalSequence analysisAdd BLAST20
Transmembranei329 – 353HelicalSequence analysisAdd BLAST25
Transmembranei365 – 384HelicalSequence analysisAdd BLAST20
Transmembranei396 – 414HelicalSequence analysisAdd BLAST19

Keywords - Cellular componenti

Membrane

Expressioni

Gene expression databases

BgeeiENSMUSG00000032114

Interactioni

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000129564

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini13 – 419MFSInterPro annotationAdd BLAST407

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

eggNOGiENOG410IP3Z Eukaryota
COG2271 LUCA
GeneTreeiENSGT00730000111086
HOVERGENiHBG051682
KOiK08171
OMAiCTDWGQF
OrthoDBiEOG091G06B9
TreeFamiTF314991

Family and domain databases

CDDicd06174 MFS, 1 hit
InterProiView protein in InterPro
IPR011701 MFS
IPR020846 MFS_dom
IPR036259 MFS_trans_sf
IPR021159 Sugar-P_transporter_CS
IPR000849 Sugar_P_transporter
PfamiView protein in Pfam
PF07690 MFS_1, 1 hit
PIRSFiPIRSF002808 Hexose_phosphate_transp, 1 hit
SUPFAMiSSF103473 SSF103473, 1 hit
PROSITEiView protein in PROSITE
PS00942 GLPT, 1 hit
PS50850 MFS, 1 hit

Sequencei

Sequence statusi: Complete.

Q9D1F9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAAQGYGYYR TVIFAAMFGG YSLYYFNRKT FSFVMPSLVD EIALDKDDLG
60 70 80 90 100
LITSSQSAAY AISKFVSGVL SDQMSARWLF SSGLLLVGLV NVVFSWSSTV
110 120 130 140 150
SAFAALWFLN GLAQGLGWPP CGKILRKWFE PSQFGTWWAV LSTSMNLAGS
160 170 180 190 200
LGPILATILA QSYSWRSTLA LSGALCVVVS FFCLLLIHNE PADVGLRNLD
210 220 230 240 250
PAPSKGKKGS SKEESTLQDL LLSPYLWVLS TGYLVVFGVK TCCTDWGQFF
260 270 280 290 300
LIQERGQSAL VGSSYISALE VGGLVGSIAA GYLSDRAMAK AGLSLYGNPR
310 320 330 340 350
HGLLLLMMAG MAASMFLFRV TVTSDSPKIW ILVLGAVFGF SSYGPIALFG
360 370 380 390 400
VIANESAPPN LCGTSHAIVG LMANVGGFLA GLPFSTIAKH YSWSTAFWVA
410 420
EVVCGASTVV FFLLRNIRTK MGRVSKKGE
Length:429
Mass (Da):46,064
Last modified:June 1, 2001 - v1
Checksum:i8C210CB489BC376E
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC122428 Genomic DNA No translation available.
BC075655 mRNA Translation: AAH75655.1
AK003620 mRNA Translation: BAB22894.1
AK155339 mRNA Translation: BAE33203.1
CH466522 Genomic DNA Translation: EDL25587.1
RefSeqiNP_001280559.1, NM_001293630.1
NP_001280560.1, NM_001293631.1
NP_032089.2, NM_008063.2
XP_006510076.1, XM_006510013.3
UniGeneiMm.30087
Mm.486672

Genome annotation databases

EnsembliENSMUST00000165839; ENSMUSP00000129564; ENSMUSG00000032114
ENSMUST00000213388; ENSMUSP00000150843; ENSMUSG00000032114
ENSMUST00000215420; ENSMUSP00000148956; ENSMUSG00000032114
GeneIDi14385
KEGGimmu:14385
UCSCiuc009pdh.2 mouse

Similar proteinsi

Entry informationi

Entry nameiQ9D1F9_MOUSE
AccessioniPrimary (citable) accession number: Q9D1F9
Entry historyiIntegrated into UniProtKB/TrEMBL: June 1, 2001
Last sequence update: June 1, 2001
Last modified: April 25, 2018
This is version 140 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
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Main funding by: National Institutes of Health