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Protein
Submitted name:

Solute carrier family 37 (Glycerol-6-phosphate transporter), member 4

Gene

Slc37a4

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: Annotation score: 5 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

  • cellular calcium ion homeostasis Source: MGI
  • cholesterol homeostasis Source: MGI
  • cytokine production Source: MGI
  • glucose-6-phosphate transport Source: MGI
  • glucose homeostasis Source: MGI
  • glycogen metabolic process Source: MGI
  • lactate metabolic process Source: MGI
  • myeloid progenitor cell differentiation Source: MGI
  • negative regulation of chemokine production Source: MGI
  • neutrophil chemotaxis Source: MGI
  • neutrophil homeostasis Source: MGI
  • phosphate ion transmembrane transport Source: MGI
  • positive regulation of catalytic activity Source: MGI
  • post-embryonic hemopoiesis Source: MGI
  • respiratory burst Source: MGI
  • response to glucose Source: Ensembl
  • response to nutrient Source: Ensembl
  • response to organic cyclic compound Source: Ensembl
  • steroid metabolic process Source: MGI
  • triglyceride metabolic process Source: MGI

Names & Taxonomyi

Protein namesi
Submitted name:
Solute carrier family 37 (Glycerol-6-phosphate transporter), member 4Imported
Submitted name:
Solute carrier family 37 (glucose-6-phosphate transporter), member 4Imported
Gene namesi
Name:Slc37a4Imported
ORF Names:mCG_10718Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 9

Organism-specific databases

MGIiMGI:1316650. Slc37a4.

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei6 – 26HelicalSequence analysisAdd BLAST21
Transmembranei84 – 109HelicalSequence analysisAdd BLAST26
Transmembranei137 – 160HelicalSequence analysisAdd BLAST24
Transmembranei167 – 187HelicalSequence analysisAdd BLAST21
Transmembranei225 – 247HelicalSequence analysisAdd BLAST23
Transmembranei259 – 283HelicalSequence analysisAdd BLAST25
Transmembranei303 – 322HelicalSequence analysisAdd BLAST20
Transmembranei329 – 353HelicalSequence analysisAdd BLAST25
Transmembranei365 – 384HelicalSequence analysisAdd BLAST20
Transmembranei396 – 414HelicalSequence analysisAdd BLAST19

Keywords - Cellular componenti

Membrane

Expressioni

Gene expression databases

BgeeiENSMUSG00000032114.

Interactioni

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000129564.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini13 – 419MFSInterPro annotationAdd BLAST407

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

eggNOGiENOG410IP3Z. Eukaryota.
COG2271. LUCA.
GeneTreeiENSGT00730000111086.
HOVERGENiHBG051682.
KOiK08171.
OMAiCTDWGQF.
OrthoDBiEOG091G06B9.
TreeFamiTF314991.

Family and domain databases

CDDicd06174. MFS. 1 hit.
InterProiView protein in InterPro
IPR011701. MFS.
IPR020846. MFS_dom.
IPR036259. MFS_trans_sf.
IPR021159. Sugar-P_transporter_CS.
IPR000849. Sugar_P_transporter.
PfamiView protein in Pfam
PF07690. MFS_1. 1 hit.
PIRSFiPIRSF002808. Hexose_phosphate_transp. 1 hit.
SUPFAMiSSF103473. SSF103473. 1 hit.
PROSITEiView protein in PROSITE
PS00942. GLPT. 1 hit.
PS50850. MFS. 1 hit.

Sequencei

Sequence statusi: Complete.

Q9D1F9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAAQGYGYYR TVIFAAMFGG YSLYYFNRKT FSFVMPSLVD EIALDKDDLG
60 70 80 90 100
LITSSQSAAY AISKFVSGVL SDQMSARWLF SSGLLLVGLV NVVFSWSSTV
110 120 130 140 150
SAFAALWFLN GLAQGLGWPP CGKILRKWFE PSQFGTWWAV LSTSMNLAGS
160 170 180 190 200
LGPILATILA QSYSWRSTLA LSGALCVVVS FFCLLLIHNE PADVGLRNLD
210 220 230 240 250
PAPSKGKKGS SKEESTLQDL LLSPYLWVLS TGYLVVFGVK TCCTDWGQFF
260 270 280 290 300
LIQERGQSAL VGSSYISALE VGGLVGSIAA GYLSDRAMAK AGLSLYGNPR
310 320 330 340 350
HGLLLLMMAG MAASMFLFRV TVTSDSPKIW ILVLGAVFGF SSYGPIALFG
360 370 380 390 400
VIANESAPPN LCGTSHAIVG LMANVGGFLA GLPFSTIAKH YSWSTAFWVA
410 420
EVVCGASTVV FFLLRNIRTK MGRVSKKGE
Length:429
Mass (Da):46,064
Last modified:June 1, 2001 - v1
Checksum:i8C210CB489BC376E
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC122428 Genomic DNA. No translation available.
BC075655 mRNA. Translation: AAH75655.1.
AK003620 mRNA. Translation: BAB22894.1.
AK155339 mRNA. Translation: BAE33203.1.
CH466522 Genomic DNA. Translation: EDL25587.1.
RefSeqiNP_001280559.1. NM_001293630.1.
NP_001280560.1. NM_001293631.1.
NP_032089.2. NM_008063.2.
XP_006510076.1. XM_006510013.3.
UniGeneiMm.30087.
Mm.486672.

Genome annotation databases

EnsembliENSMUST00000165839; ENSMUSP00000129564; ENSMUSG00000032114.
ENSMUST00000213388; ENSMUSP00000150843; ENSMUSG00000032114.
ENSMUST00000215420; ENSMUSP00000148956; ENSMUSG00000032114.
GeneIDi14385.
KEGGimmu:14385.
UCSCiuc009pdh.2. mouse.

Similar proteinsi

Entry informationi

Entry nameiQ9D1F9_MOUSE
AccessioniPrimary (citable) accession number: Q9D1F9
Entry historyiIntegrated into UniProtKB/TrEMBL: June 1, 2001
Last sequence update: June 1, 2001
Last modified: October 25, 2017
This is version 135 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported