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Protein

Ribosomal RNA-processing protein 7 homolog A

Gene

Rrp7a

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

GO - Biological processi

  • blastocyst formation Source: MGI
  • ribosomal small subunit assembly Source: GO_Central
  • rRNA processing Source: GO_Central
Complete GO annotation...

Keywords - Ligandi

RNA-binding

Enzyme and pathway databases

ReactomeiR-MMU-6791226. Major pathway of rRNA processing in the nucleolus and cytosol.

Names & Taxonomyi

Protein namesi
Recommended name:
Ribosomal RNA-processing protein 7 homolog A
Alternative name(s):
Gastric cancer antigen Zg14 homolog
Gene namesi
Name:Rrp7a
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 15

Organism-specific databases

MGIiMGI:1922028. Rrp7a.

Subcellular locationi

GO - Cellular componenti

  • CURI complex Source: GO_Central
  • cytoplasm Source: MGI
  • UTP-C complex Source: GO_Central
Complete GO annotation...

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000820091 – 280Ribosomal RNA-processing protein 7 homolog AAdd BLAST280

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei99PhosphoserineBy similarity1

Keywords - PTMi

Phosphoprotein

Proteomic databases

EPDiQ9D1C9.
MaxQBiQ9D1C9.
PaxDbiQ9D1C9.
PRIDEiQ9D1C9.

PTM databases

iPTMnetiQ9D1C9.
PhosphoSitePlusiQ9D1C9.

Expressioni

Gene expression databases

BgeeiENSMUSG00000018040.
ExpressionAtlasiQ9D1C9. baseline and differential.
GenevisibleiQ9D1C9. MM.

Interactioni

Protein-protein interaction databases

BioGridi217014. 1 interactor.
IntActiQ9D1C9. 1 interactor.
MINTiMINT-4126548.
STRINGi10090.ENSMUSP00000018184.

Structurei

3D structure databases

ProteinModelPortaliQ9D1C9.
SMRiQ9D1C9.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini61 – 90RRMAdd BLAST30

Sequence similaritiesi

Belongs to the RRP7 family.Curated

Phylogenomic databases

eggNOGiKOG4008. Eukaryota.
ENOG410YHJN. LUCA.
GeneTreeiENSGT00390000018482.
HOGENOMiHOG000007041.
HOVERGENiHBG054483.
InParanoidiQ9D1C9.
KOiK14545.
OMAiFQIHEKK.
OrthoDBiEOG091G0JTG.
PhylomeDBiQ9D1C9.
TreeFamiTF313949.

Family and domain databases

Gene3Di3.30.70.330. 1 hit.
InterProiIPR012677. Nucleotide-bd_a/b_plait.
IPR024326. RRP7.
[Graphical view]
PANTHERiPTHR13191. PTHR13191. 1 hit.
PfamiPF12923. RRP7. 1 hit.
[Graphical view]
SUPFAMiSSF54928. SSF54928. 1 hit.

Sequencei

Sequence statusi: Complete.

Q9D1C9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MVSRRKKRKA GGHEESIPSP PGYSAVPVKF SAKQQAPHYL YMRQHRVRQG
60 70 80 90 100
TQSTWPPDRT LFILNVPPYC TQESLSRCLS CCGTIKTVEL QEKPDLAESP
110 120 130 140 150
TEPKSQFFHP KPVPGFQVAY VVFQKPSGVS AALNLKGPLL VSTESHLVKS
160 170 180 190 200
GIHKWISDYE DSVLDPEALR MEVDAFMEAY DKKIAEEEAK AKEEEGVPDE
210 220 230 240 250
EGWVKVTRRG RRPVLPRTEA ASLRVLEKEK RKRARKELLN FYAWQHRETK
260 270 280
MEHLAQLRKK FEEDKQRIEL MRAQRKFRPY
Length:280
Mass (Da):32,399
Last modified:June 1, 2001 - v1
Checksum:i4F2D324221B2AA3F
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti103P → Q in BAC27942 (PubMed:16141072).Curated1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK003698 mRNA. Translation: BAB22944.1.
AK032596 mRNA. Translation: BAC27942.1.
AK036247 mRNA. Translation: BAC29360.1.
AK088456 mRNA. Translation: BAC40363.1.
AK146821 mRNA. Translation: BAE27459.1.
AK159553 mRNA. Translation: BAE35178.1.
AK168189 mRNA. Translation: BAE40149.1.
AK168850 mRNA. Translation: BAE40672.1.
BC012523 mRNA. Translation: AAH12523.1.
CCDSiCCDS27696.1.
RefSeqiNP_083377.3. NM_029101.4.
UniGeneiMm.30056.
Mm.452636.

Genome annotation databases

EnsembliENSMUST00000018184; ENSMUSP00000018184; ENSMUSG00000018040.
GeneIDi74778.
KEGGimmu:74778.
UCSCiuc007wzy.3. mouse.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK003698 mRNA. Translation: BAB22944.1.
AK032596 mRNA. Translation: BAC27942.1.
AK036247 mRNA. Translation: BAC29360.1.
AK088456 mRNA. Translation: BAC40363.1.
AK146821 mRNA. Translation: BAE27459.1.
AK159553 mRNA. Translation: BAE35178.1.
AK168189 mRNA. Translation: BAE40149.1.
AK168850 mRNA. Translation: BAE40672.1.
BC012523 mRNA. Translation: AAH12523.1.
CCDSiCCDS27696.1.
RefSeqiNP_083377.3. NM_029101.4.
UniGeneiMm.30056.
Mm.452636.

3D structure databases

ProteinModelPortaliQ9D1C9.
SMRiQ9D1C9.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi217014. 1 interactor.
IntActiQ9D1C9. 1 interactor.
MINTiMINT-4126548.
STRINGi10090.ENSMUSP00000018184.

PTM databases

iPTMnetiQ9D1C9.
PhosphoSitePlusiQ9D1C9.

Proteomic databases

EPDiQ9D1C9.
MaxQBiQ9D1C9.
PaxDbiQ9D1C9.
PRIDEiQ9D1C9.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000018184; ENSMUSP00000018184; ENSMUSG00000018040.
GeneIDi74778.
KEGGimmu:74778.
UCSCiuc007wzy.3. mouse.

Organism-specific databases

CTDi27341.
MGIiMGI:1922028. Rrp7a.

Phylogenomic databases

eggNOGiKOG4008. Eukaryota.
ENOG410YHJN. LUCA.
GeneTreeiENSGT00390000018482.
HOGENOMiHOG000007041.
HOVERGENiHBG054483.
InParanoidiQ9D1C9.
KOiK14545.
OMAiFQIHEKK.
OrthoDBiEOG091G0JTG.
PhylomeDBiQ9D1C9.
TreeFamiTF313949.

Enzyme and pathway databases

ReactomeiR-MMU-6791226. Major pathway of rRNA processing in the nucleolus and cytosol.

Miscellaneous databases

PROiQ9D1C9.
SOURCEiSearch...

Gene expression databases

BgeeiENSMUSG00000018040.
ExpressionAtlasiQ9D1C9. baseline and differential.
GenevisibleiQ9D1C9. MM.

Family and domain databases

Gene3Di3.30.70.330. 1 hit.
InterProiIPR012677. Nucleotide-bd_a/b_plait.
IPR024326. RRP7.
[Graphical view]
PANTHERiPTHR13191. PTHR13191. 1 hit.
PfamiPF12923. RRP7. 1 hit.
[Graphical view]
SUPFAMiSSF54928. SSF54928. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiRRP7A_MOUSE
AccessioniPrimary (citable) accession number: Q9D1C9
Secondary accession number(s): Q3TWT8, Q8CCK8
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 24, 2005
Last sequence update: June 1, 2001
Last modified: November 2, 2016
This is version 113 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.