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Q9D131

- CK001_MOUSE

UniProt

Q9D131 - CK001_MOUSE

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Protein

UPF0686 protein C11orf1 homolog

Gene
N/A
Organism
Mus musculus (Mouse)
Status
Reviewed - Annotation score: 2 out of 5- Experimental evidence at transcript leveli

Names & Taxonomyi

Protein namesi
Recommended name:
UPF0686 protein C11orf1 homolog
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
ProteomesiUP000000589: Chromosome 9

Organism-specific databases

MGIiMGI:1915971. 1110032A03Rik.

Subcellular locationi

Nucleus By similarity

GO - Cellular componenti

  1. nucleus Source: UniProtKB-KW
Complete GO annotation...

Keywords - Cellular componenti

Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 166166UPF0686 protein C11orf1 homologPRO_0000089830Add
BLAST

Proteomic databases

PRIDEiQ9D131.

PTM databases

PhosphoSiteiQ9D131.

Expressioni

Gene expression databases

BgeeiQ9D131.
CleanExiMM_1110032A03RIK.
ExpressionAtlasiQ9D131. baseline and differential.
GenevestigatoriQ9D131.

Family & Domainsi

Sequence similaritiesi

Belongs to the UPF0686 family.Curated

Phylogenomic databases

eggNOGiNOG39668.
GeneTreeiENSGT00390000002905.
HOVERGENiHBG050969.
InParanoidiQ9D131.
OMAiELDPPQY.
OrthoDBiEOG71G9W5.
PhylomeDBiQ9D131.
TreeFamiTF329225.

Family and domain databases

InterProiIPR009524. UPF0686.
[Graphical view]
PfamiPF06608. DUF1143. 1 hit.
[Graphical view]

Sequences (2)i

Sequence statusi: Complete.

This entry describes 2 isoformsi produced by alternative splicing. Align

Isoform 1 (identifier: Q9D131-1) [UniParc]FASTAAdd to Basket

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide

        10         20         30         40         50
MAVSCSLNHS TYLQRQNLVC YLRNPHYGSL IYADGHGEVW TDWNDMSKFL
60 70 80 90 100
QYGWRCTTNE NSYSNRTLVG NWNQERYDLK NIVKPKPLPS QFGHAFETTY
110 120 130 140 150
DANYSRKKPQ STHRFKREPH WFPGHQPELD PPHYKCTAKS TYMTNYSEPQ
160
PTHYSCCVYD PSVSQS
Length:166
Mass (Da):19,527
Last modified:June 1, 2001 - v1
Checksum:iB299BEE9DB28E0EC
GO
Isoform 2 (identifier: Q9D131-2) [UniParc]FASTAAdd to Basket

The sequence of this isoform differs from the canonical sequence as follows:
     1-13: MAVSCSLNHSTYL → MELPYRNRFYSLRCSSKSLYSPSSYTSII

Note: No experimental confirmation available.

Show »
Length:182
Mass (Da):21,551
Checksum:iAF5E65013478DA2B
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sequence conflicti8 – 81N → S in CAB96546. (PubMed:10873569)Curated
Sequence conflicti8 – 81N → S in BAE34519. (PubMed:16141072)Curated
Sequence conflicti14 – 141Q → K in CAB96546. (PubMed:10873569)Curated
Sequence conflicti14 – 141Q → K in BAE34519. (PubMed:16141072)Curated
Sequence conflicti158 – 1581V → I in BC032012. (PubMed:15489334)Curated

Natural variant

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Natural varianti166 – 1661S → SQGPGI.2 Publications

Alternative sequence

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Alternative sequencei1 – 1313MAVSC…HSTYL → MELPYRNRFYSLRCSSKSLY SPSSYTSII in isoform 2. 1 PublicationVSP_027584Add
BLAST

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AJ250230 mRNA. Translation: CAB96546.1.
AK004016 mRNA. Translation: BAB23127.1.
AK015671 mRNA. Translation: BAB29923.1.
AK043513 mRNA. Translation: BAC31564.1.
AK158460 mRNA. Translation: BAE34519.1.
AK166202 mRNA. Translation: BAE38625.1.
CT010205 mRNA. Translation: CAJ18413.1.
BC032012 mRNA. No translation available.
CCDSiCCDS23173.1. [Q9D131-1]
RefSeqiNP_075972.2. NM_023483.3. [Q9D131-1]
XP_006510640.1. XM_006510577.1. [Q9D131-2]
UniGeneiMm.171374.
Mm.432356.

Genome annotation databases

EnsembliENSMUST00000042468; ENSMUSP00000041803; ENSMUSG00000037971. [Q9D131-1]
ENSMUST00000042576; ENSMUSP00000046890; ENSMUSG00000037971. [Q9D131-2]
GeneIDi68721.
KEGGimmu:68721.
UCSCiuc009pko.1. mouse. [Q9D131-2]
uc009pkp.1. mouse. [Q9D131-1]

Keywords - Coding sequence diversityi

Alternative splicing, Polymorphism

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AJ250230 mRNA. Translation: CAB96546.1 .
AK004016 mRNA. Translation: BAB23127.1 .
AK015671 mRNA. Translation: BAB29923.1 .
AK043513 mRNA. Translation: BAC31564.1 .
AK158460 mRNA. Translation: BAE34519.1 .
AK166202 mRNA. Translation: BAE38625.1 .
CT010205 mRNA. Translation: CAJ18413.1 .
BC032012 mRNA. No translation available.
CCDSi CCDS23173.1. [Q9D131-1 ]
RefSeqi NP_075972.2. NM_023483.3. [Q9D131-1 ]
XP_006510640.1. XM_006510577.1. [Q9D131-2 ]
UniGenei Mm.171374.
Mm.432356.

3D structure databases

ModBasei Search...
MobiDBi Search...

PTM databases

PhosphoSitei Q9D131.

Proteomic databases

PRIDEi Q9D131.

Protocols and materials databases

DNASUi 68721.
Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENSMUST00000042468 ; ENSMUSP00000041803 ; ENSMUSG00000037971 . [Q9D131-1 ]
ENSMUST00000042576 ; ENSMUSP00000046890 ; ENSMUSG00000037971 . [Q9D131-2 ]
GeneIDi 68721.
KEGGi mmu:68721.
UCSCi uc009pko.1. mouse. [Q9D131-2 ]
uc009pkp.1. mouse. [Q9D131-1 ]

Organism-specific databases

MGIi MGI:1915971. 1110032A03Rik.

Phylogenomic databases

eggNOGi NOG39668.
GeneTreei ENSGT00390000002905.
HOVERGENi HBG050969.
InParanoidi Q9D131.
OMAi ELDPPQY.
OrthoDBi EOG71G9W5.
PhylomeDBi Q9D131.
TreeFami TF329225.

Miscellaneous databases

NextBioi 327758.

Gene expression databases

Bgeei Q9D131.
CleanExi MM_1110032A03RIK.
ExpressionAtlasi Q9D131. baseline and differential.
Genevestigatori Q9D131.

Family and domain databases

InterProi IPR009524. UPF0686.
[Graphical view ]
Pfami PF06608. DUF1143. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1).
  2. "The transcriptional landscape of the mammalian genome."
    Carninci P., Kasukawa T., Katayama S., Gough J., Frith M.C., Maeda N., Oyama R., Ravasi T., Lenhard B., Wells C., Kodzius R., Shimokawa K., Bajic V.B., Brenner S.E., Batalov S., Forrest A.R., Zavolan M., Davis M.J.
    , Wilming L.G., Aidinis V., Allen J.E., Ambesi-Impiombato A., Apweiler R., Aturaliya R.N., Bailey T.L., Bansal M., Baxter L., Beisel K.W., Bersano T., Bono H., Chalk A.M., Chiu K.P., Choudhary V., Christoffels A., Clutterbuck D.R., Crowe M.L., Dalla E., Dalrymple B.P., de Bono B., Della Gatta G., di Bernardo D., Down T., Engstrom P., Fagiolini M., Faulkner G., Fletcher C.F., Fukushima T., Furuno M., Futaki S., Gariboldi M., Georgii-Hemming P., Gingeras T.R., Gojobori T., Green R.E., Gustincich S., Harbers M., Hayashi Y., Hensch T.K., Hirokawa N., Hill D., Huminiecki L., Iacono M., Ikeo K., Iwama A., Ishikawa T., Jakt M., Kanapin A., Katoh M., Kawasawa Y., Kelso J., Kitamura H., Kitano H., Kollias G., Krishnan S.P., Kruger A., Kummerfeld S.K., Kurochkin I.V., Lareau L.F., Lazarevic D., Lipovich L., Liu J., Liuni S., McWilliam S., Madan Babu M., Madera M., Marchionni L., Matsuda H., Matsuzawa S., Miki H., Mignone F., Miyake S., Morris K., Mottagui-Tabar S., Mulder N., Nakano N., Nakauchi H., Ng P., Nilsson R., Nishiguchi S., Nishikawa S., Nori F., Ohara O., Okazaki Y., Orlando V., Pang K.C., Pavan W.J., Pavesi G., Pesole G., Petrovsky N., Piazza S., Reed J., Reid J.F., Ring B.Z., Ringwald M., Rost B., Ruan Y., Salzberg S.L., Sandelin A., Schneider C., Schoenbach C., Sekiguchi K., Semple C.A., Seno S., Sessa L., Sheng Y., Shibata Y., Shimada H., Shimada K., Silva D., Sinclair B., Sperling S., Stupka E., Sugiura K., Sultana R., Takenaka Y., Taki K., Tammoja K., Tan S.L., Tang S., Taylor M.S., Tegner J., Teichmann S.A., Ueda H.R., van Nimwegen E., Verardo R., Wei C.L., Yagi K., Yamanishi H., Zabarovsky E., Zhu S., Zimmer A., Hide W., Bult C., Grimmond S.M., Teasdale R.D., Liu E.T., Brusic V., Quackenbush J., Wahlestedt C., Mattick J.S., Hume D.A., Kai C., Sasaki D., Tomaru Y., Fukuda S., Kanamori-Katayama M., Suzuki M., Aoki J., Arakawa T., Iida J., Imamura K., Itoh M., Kato T., Kawaji H., Kawagashira N., Kawashima T., Kojima M., Kondo S., Konno H., Nakano K., Ninomiya N., Nishio T., Okada M., Plessy C., Shibata K., Shiraki T., Suzuki S., Tagami M., Waki K., Watahiki A., Okamura-Oho Y., Suzuki H., Kawai J., Hayashizaki Y.
    Science 309:1559-1563(2005) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 1 AND 2), VARIANT GLN-GLY-PRO-GLY-ILE-166 INS.
    Strain: C57BL/6J.
    Tissue: Brain cortex, Embryo, Inner ear, Mammary gland and Testis.
  3. "Cloning of mouse full open reading frames in Gateway(R) system entry vector (pDONR201)."
    Ebert L., Muenstermann E., Schatten R., Henze S., Bohn E., Mollenhauer J., Wiemann S., Schick M., Korn B.
    Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1).
  4. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1), VARIANT GLN-GLY-PRO-GLY-ILE-166 INS.
    Tissue: Mammary tumor.

Entry informationi

Entry nameiCK001_MOUSE
AccessioniPrimary (citable) accession number: Q9D131
Secondary accession number(s): Q3TM17
, Q3TYP3, Q4FK47, Q8K0A6, Q9D589, Q9JHT0
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 24, 2004
Last sequence update: June 1, 2001
Last modified: October 29, 2014
This is version 77 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
  2. SIMILARITY comments
    Index of protein domains and families
  3. Uncharacterized protein families (UPF)
    List of uncharacterized protein family (UPF) entries

External Data

Dasty 3