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Q9D131 (CK001_MOUSE) Reviewed, UniProtKB/Swiss-Prot

Last modified July 9, 2014. Version 75. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (3) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Alt products·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
UPF0686 protein C11orf1 homolog
OrganismMus musculus (Mouse) [Reference proteome]
Taxonomic identifier10090 [NCBI]
Taxonomic lineageEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus

Protein attributes

Sequence length166 AA.
Sequence statusComplete.
Protein existenceEvidence at transcript level

General annotation (Comments)

Subcellular location

Nucleus By similarity.

Sequence similarities

Belongs to the UPF0686 family.

Ontologies

Keywords
   Cellular componentNucleus
   Coding sequence diversityAlternative splicing
Polymorphism
   Technical termComplete proteome
Reference proteome
Gene Ontology (GO)
   Cellular_componentnucleus

Inferred from electronic annotation. Source: UniProtKB-SubCell

Complete GO annotation...

Alternative products

This entry describes 2 isoforms produced by alternative splicing. [Align] [Select]
Isoform 1 (identifier: Q9D131-1)

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.
Isoform 2 (identifier: Q9D131-2)

The sequence of this isoform differs from the canonical sequence as follows:
     1-13: MAVSCSLNHSTYL → MELPYRNRFYSLRCSSKSLYSPSSYTSII
Note: No experimental confirmation available.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 166166UPF0686 protein C11orf1 homolog
PRO_0000089830

Natural variations

Alternative sequence1 – 1313MAVSC…HSTYL → MELPYRNRFYSLRCSSKSLY SPSSYTSII in isoform 2.
VSP_027584
Natural variant1661S → SQGPGI.

Experimental info

Sequence conflict81N → S in CAB96546. Ref.1
Sequence conflict81N → S in BAE34519. Ref.2
Sequence conflict141Q → K in CAB96546. Ref.1
Sequence conflict141Q → K in BAE34519. Ref.2
Sequence conflict1581V → I in BC032012. Ref.4

Sequences

Sequence LengthMass (Da)Tools
Isoform 1 [UniParc].

Last modified June 1, 2001. Version 1.
Checksum: B299BEE9DB28E0EC

FASTA16619,527
        10         20         30         40         50         60 
MAVSCSLNHS TYLQRQNLVC YLRNPHYGSL IYADGHGEVW TDWNDMSKFL QYGWRCTTNE 

        70         80         90        100        110        120 
NSYSNRTLVG NWNQERYDLK NIVKPKPLPS QFGHAFETTY DANYSRKKPQ STHRFKREPH 

       130        140        150        160 
WFPGHQPELD PPHYKCTAKS TYMTNYSEPQ PTHYSCCVYD PSVSQS 

« Hide

Isoform 2 [UniParc].

Checksum: AF5E65013478DA2B
Show »

FASTA18221,551

References

« Hide 'large scale' references
[1]"Characterization of five novel human genes in the 11q13-q22 region."
O'Brien K.P., Tapia-Paez I., Staahle-Baeckdahl M., Kedra D., Dumanski J.P.
Biochem. Biophys. Res. Commun. 273:90-94(2000) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1).
[2]"The transcriptional landscape of the mammalian genome."
Carninci P., Kasukawa T., Katayama S., Gough J., Frith M.C., Maeda N., Oyama R., Ravasi T., Lenhard B., Wells C., Kodzius R., Shimokawa K., Bajic V.B., Brenner S.E., Batalov S., Forrest A.R., Zavolan M., Davis M.J. expand/collapse author list , Wilming L.G., Aidinis V., Allen J.E., Ambesi-Impiombato A., Apweiler R., Aturaliya R.N., Bailey T.L., Bansal M., Baxter L., Beisel K.W., Bersano T., Bono H., Chalk A.M., Chiu K.P., Choudhary V., Christoffels A., Clutterbuck D.R., Crowe M.L., Dalla E., Dalrymple B.P., de Bono B., Della Gatta G., di Bernardo D., Down T., Engstrom P., Fagiolini M., Faulkner G., Fletcher C.F., Fukushima T., Furuno M., Futaki S., Gariboldi M., Georgii-Hemming P., Gingeras T.R., Gojobori T., Green R.E., Gustincich S., Harbers M., Hayashi Y., Hensch T.K., Hirokawa N., Hill D., Huminiecki L., Iacono M., Ikeo K., Iwama A., Ishikawa T., Jakt M., Kanapin A., Katoh M., Kawasawa Y., Kelso J., Kitamura H., Kitano H., Kollias G., Krishnan S.P., Kruger A., Kummerfeld S.K., Kurochkin I.V., Lareau L.F., Lazarevic D., Lipovich L., Liu J., Liuni S., McWilliam S., Madan Babu M., Madera M., Marchionni L., Matsuda H., Matsuzawa S., Miki H., Mignone F., Miyake S., Morris K., Mottagui-Tabar S., Mulder N., Nakano N., Nakauchi H., Ng P., Nilsson R., Nishiguchi S., Nishikawa S., Nori F., Ohara O., Okazaki Y., Orlando V., Pang K.C., Pavan W.J., Pavesi G., Pesole G., Petrovsky N., Piazza S., Reed J., Reid J.F., Ring B.Z., Ringwald M., Rost B., Ruan Y., Salzberg S.L., Sandelin A., Schneider C., Schoenbach C., Sekiguchi K., Semple C.A., Seno S., Sessa L., Sheng Y., Shibata Y., Shimada H., Shimada K., Silva D., Sinclair B., Sperling S., Stupka E., Sugiura K., Sultana R., Takenaka Y., Taki K., Tammoja K., Tan S.L., Tang S., Taylor M.S., Tegner J., Teichmann S.A., Ueda H.R., van Nimwegen E., Verardo R., Wei C.L., Yagi K., Yamanishi H., Zabarovsky E., Zhu S., Zimmer A., Hide W., Bult C., Grimmond S.M., Teasdale R.D., Liu E.T., Brusic V., Quackenbush J., Wahlestedt C., Mattick J.S., Hume D.A., Kai C., Sasaki D., Tomaru Y., Fukuda S., Kanamori-Katayama M., Suzuki M., Aoki J., Arakawa T., Iida J., Imamura K., Itoh M., Kato T., Kawaji H., Kawagashira N., Kawashima T., Kojima M., Kondo S., Konno H., Nakano K., Ninomiya N., Nishio T., Okada M., Plessy C., Shibata K., Shiraki T., Suzuki S., Tagami M., Waki K., Watahiki A., Okamura-Oho Y., Suzuki H., Kawai J., Hayashizaki Y.
Science 309:1559-1563(2005) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 1 AND 2), VARIANT GLN-GLY-PRO-GLY-ILE-166 INS.
Strain: C57BL/6J.
Tissue: Brain cortex, Embryo, Inner ear, Mammary gland and Testis.
[3]"Cloning of mouse full open reading frames in Gateway(R) system entry vector (pDONR201)."
Ebert L., Muenstermann E., Schatten R., Henze S., Bohn E., Mollenhauer J., Wiemann S., Schick M., Korn B.
Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1).
[4]"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1), VARIANT GLN-GLY-PRO-GLY-ILE-166 INS.
Tissue: Mammary tumor.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AJ250230 mRNA. Translation: CAB96546.1.
AK004016 mRNA. Translation: BAB23127.1.
AK015671 mRNA. Translation: BAB29923.1.
AK043513 mRNA. Translation: BAC31564.1.
AK158460 mRNA. Translation: BAE34519.1.
AK166202 mRNA. Translation: BAE38625.1.
CT010205 mRNA. Translation: CAJ18413.1.
BC032012 mRNA. No translation available.
CCDSCCDS23173.1. [Q9D131-1]
RefSeqNP_075972.2. NM_023483.3. [Q9D131-1]
XP_006510640.1. XM_006510577.1. [Q9D131-2]
UniGeneMm.171374.
Mm.432356.

3D structure databases

ModBaseSearch...
MobiDBSearch...

PTM databases

PhosphoSiteQ9D131.

Proteomic databases

PRIDEQ9D131.

Protocols and materials databases

DNASU68721.
StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblENSMUST00000042468; ENSMUSP00000041803; ENSMUSG00000037971. [Q9D131-1]
ENSMUST00000042576; ENSMUSP00000046890; ENSMUSG00000037971. [Q9D131-2]
GeneID68721.
KEGGmmu:68721.
UCSCuc009pko.1. mouse. [Q9D131-2]
uc009pkp.1. mouse. [Q9D131-1]

Organism-specific databases

MGIMGI:1915971. 1110032A03Rik.

Phylogenomic databases

eggNOGNOG39668.
GeneTreeENSGT00390000002905.
HOVERGENHBG050969.
OMAELDPPQY.
OrthoDBEOG71G9W5.
PhylomeDBQ9D131.
TreeFamTF329225.

Gene expression databases

ArrayExpressQ9D131.
BgeeQ9D131.
CleanExMM_1110032A03RIK.
GenevestigatorQ9D131.

Family and domain databases

InterProIPR009524. UPF0686.
[Graphical view]
PfamPF06608. DUF1143. 1 hit.
[Graphical view]
ProtoNetSearch...

Other

NextBio327758.

Entry information

Entry nameCK001_MOUSE
AccessionPrimary (citable) accession number: Q9D131
Secondary accession number(s): Q3TM17 expand/collapse secondary AC list , Q3TYP3, Q4FK47, Q8K0A6, Q9D589, Q9JHT0
Entry history
Integrated into UniProtKB/Swiss-Prot: May 24, 2004
Last sequence update: June 1, 2001
Last modified: July 9, 2014
This is version 75 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Relevant documents

Uncharacterized protein families (UPF)

List of uncharacterized protein family (UPF) entries

SIMILARITY comments

Index of protein domains and families

MGD cross-references

Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot