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Q9D131

- CK001_MOUSE

UniProt

Q9D131 - CK001_MOUSE

Protein

UPF0686 protein C11orf1 homolog

Gene
N/A
Organism
Mus musculus (Mouse)
Status
Reviewed - Annotation score: 2 out of 5- Experimental evidence at transcript leveli
  1. Names & Taxonomyi

    Protein namesi
    Recommended name:
    UPF0686 protein C11orf1 homolog
    OrganismiMus musculus (Mouse)
    Taxonomic identifieri10090 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
    ProteomesiUP000000589: Chromosome 9

    Organism-specific databases

    MGIiMGI:1915971. 1110032A03Rik.

    Subcellular locationi

    Nucleus By similarity

    GO - Cellular componenti

    1. nucleus Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Nucleus

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 166166UPF0686 protein C11orf1 homologPRO_0000089830Add
    BLAST

    Proteomic databases

    PRIDEiQ9D131.

    PTM databases

    PhosphoSiteiQ9D131.

    Expressioni

    Gene expression databases

    ArrayExpressiQ9D131.
    BgeeiQ9D131.
    CleanExiMM_1110032A03RIK.
    GenevestigatoriQ9D131.

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the UPF0686 family.Curated

    Phylogenomic databases

    eggNOGiNOG39668.
    GeneTreeiENSGT00390000002905.
    HOVERGENiHBG050969.
    OMAiELDPPQY.
    OrthoDBiEOG71G9W5.
    PhylomeDBiQ9D131.
    TreeFamiTF329225.

    Family and domain databases

    InterProiIPR009524. UPF0686.
    [Graphical view]
    PfamiPF06608. DUF1143. 1 hit.
    [Graphical view]

    Sequences (2)i

    Sequence statusi: Complete.

    This entry describes 2 isoformsi produced by alternative splicing. Align

    Isoform 1 (identifier: Q9D131-1) [UniParc]FASTAAdd to Basket

    This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

    « Hide

    MAVSCSLNHS TYLQRQNLVC YLRNPHYGSL IYADGHGEVW TDWNDMSKFL    50
    QYGWRCTTNE NSYSNRTLVG NWNQERYDLK NIVKPKPLPS QFGHAFETTY 100
    DANYSRKKPQ STHRFKREPH WFPGHQPELD PPHYKCTAKS TYMTNYSEPQ 150
    PTHYSCCVYD PSVSQS 166
    Length:166
    Mass (Da):19,527
    Last modified:June 1, 2001 - v1
    Checksum:iB299BEE9DB28E0EC
    GO
    Isoform 2 (identifier: Q9D131-2) [UniParc]FASTAAdd to Basket

    The sequence of this isoform differs from the canonical sequence as follows:
         1-13: MAVSCSLNHSTYL → MELPYRNRFYSLRCSSKSLYSPSSYTSII

    Note: No experimental confirmation available.

    Show »
    Length:182
    Mass (Da):21,551
    Checksum:iAF5E65013478DA2B
    GO

    Experimental Info

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Sequence conflicti8 – 81N → S in CAB96546. (PubMed:10873569)Curated
    Sequence conflicti8 – 81N → S in BAE34519. (PubMed:16141072)Curated
    Sequence conflicti14 – 141Q → K in CAB96546. (PubMed:10873569)Curated
    Sequence conflicti14 – 141Q → K in BAE34519. (PubMed:16141072)Curated
    Sequence conflicti158 – 1581V → I in BC032012. (PubMed:15489334)Curated

    Natural variant

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Natural varianti166 – 1661S → SQGPGI.2 Publications

    Alternative sequence

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Alternative sequencei1 – 1313MAVSC…HSTYL → MELPYRNRFYSLRCSSKSLY SPSSYTSII in isoform 2. 1 PublicationVSP_027584Add
    BLAST

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AJ250230 mRNA. Translation: CAB96546.1.
    AK004016 mRNA. Translation: BAB23127.1.
    AK015671 mRNA. Translation: BAB29923.1.
    AK043513 mRNA. Translation: BAC31564.1.
    AK158460 mRNA. Translation: BAE34519.1.
    AK166202 mRNA. Translation: BAE38625.1.
    CT010205 mRNA. Translation: CAJ18413.1.
    BC032012 mRNA. No translation available.
    CCDSiCCDS23173.1. [Q9D131-1]
    RefSeqiNP_075972.2. NM_023483.3. [Q9D131-1]
    XP_006510640.1. XM_006510577.1. [Q9D131-2]
    UniGeneiMm.171374.
    Mm.432356.

    Genome annotation databases

    EnsembliENSMUST00000042468; ENSMUSP00000041803; ENSMUSG00000037971. [Q9D131-1]
    ENSMUST00000042576; ENSMUSP00000046890; ENSMUSG00000037971. [Q9D131-2]
    GeneIDi68721.
    KEGGimmu:68721.
    UCSCiuc009pko.1. mouse. [Q9D131-2]
    uc009pkp.1. mouse. [Q9D131-1]

    Keywords - Coding sequence diversityi

    Alternative splicing, Polymorphism

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AJ250230 mRNA. Translation: CAB96546.1 .
    AK004016 mRNA. Translation: BAB23127.1 .
    AK015671 mRNA. Translation: BAB29923.1 .
    AK043513 mRNA. Translation: BAC31564.1 .
    AK158460 mRNA. Translation: BAE34519.1 .
    AK166202 mRNA. Translation: BAE38625.1 .
    CT010205 mRNA. Translation: CAJ18413.1 .
    BC032012 mRNA. No translation available.
    CCDSi CCDS23173.1. [Q9D131-1 ]
    RefSeqi NP_075972.2. NM_023483.3. [Q9D131-1 ]
    XP_006510640.1. XM_006510577.1. [Q9D131-2 ]
    UniGenei Mm.171374.
    Mm.432356.

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    PTM databases

    PhosphoSitei Q9D131.

    Proteomic databases

    PRIDEi Q9D131.

    Protocols and materials databases

    DNASUi 68721.
    Structural Biology Knowledgebase Search...

    Genome annotation databases

    Ensembli ENSMUST00000042468 ; ENSMUSP00000041803 ; ENSMUSG00000037971 . [Q9D131-1 ]
    ENSMUST00000042576 ; ENSMUSP00000046890 ; ENSMUSG00000037971 . [Q9D131-2 ]
    GeneIDi 68721.
    KEGGi mmu:68721.
    UCSCi uc009pko.1. mouse. [Q9D131-2 ]
    uc009pkp.1. mouse. [Q9D131-1 ]

    Organism-specific databases

    MGIi MGI:1915971. 1110032A03Rik.

    Phylogenomic databases

    eggNOGi NOG39668.
    GeneTreei ENSGT00390000002905.
    HOVERGENi HBG050969.
    OMAi ELDPPQY.
    OrthoDBi EOG71G9W5.
    PhylomeDBi Q9D131.
    TreeFami TF329225.

    Miscellaneous databases

    NextBioi 327758.

    Gene expression databases

    ArrayExpressi Q9D131.
    Bgeei Q9D131.
    CleanExi MM_1110032A03RIK.
    Genevestigatori Q9D131.

    Family and domain databases

    InterProi IPR009524. UPF0686.
    [Graphical view ]
    Pfami PF06608. DUF1143. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1).
    2. "The transcriptional landscape of the mammalian genome."
      Carninci P., Kasukawa T., Katayama S., Gough J., Frith M.C., Maeda N., Oyama R., Ravasi T., Lenhard B., Wells C., Kodzius R., Shimokawa K., Bajic V.B., Brenner S.E., Batalov S., Forrest A.R., Zavolan M., Davis M.J.
      , Wilming L.G., Aidinis V., Allen J.E., Ambesi-Impiombato A., Apweiler R., Aturaliya R.N., Bailey T.L., Bansal M., Baxter L., Beisel K.W., Bersano T., Bono H., Chalk A.M., Chiu K.P., Choudhary V., Christoffels A., Clutterbuck D.R., Crowe M.L., Dalla E., Dalrymple B.P., de Bono B., Della Gatta G., di Bernardo D., Down T., Engstrom P., Fagiolini M., Faulkner G., Fletcher C.F., Fukushima T., Furuno M., Futaki S., Gariboldi M., Georgii-Hemming P., Gingeras T.R., Gojobori T., Green R.E., Gustincich S., Harbers M., Hayashi Y., Hensch T.K., Hirokawa N., Hill D., Huminiecki L., Iacono M., Ikeo K., Iwama A., Ishikawa T., Jakt M., Kanapin A., Katoh M., Kawasawa Y., Kelso J., Kitamura H., Kitano H., Kollias G., Krishnan S.P., Kruger A., Kummerfeld S.K., Kurochkin I.V., Lareau L.F., Lazarevic D., Lipovich L., Liu J., Liuni S., McWilliam S., Madan Babu M., Madera M., Marchionni L., Matsuda H., Matsuzawa S., Miki H., Mignone F., Miyake S., Morris K., Mottagui-Tabar S., Mulder N., Nakano N., Nakauchi H., Ng P., Nilsson R., Nishiguchi S., Nishikawa S., Nori F., Ohara O., Okazaki Y., Orlando V., Pang K.C., Pavan W.J., Pavesi G., Pesole G., Petrovsky N., Piazza S., Reed J., Reid J.F., Ring B.Z., Ringwald M., Rost B., Ruan Y., Salzberg S.L., Sandelin A., Schneider C., Schoenbach C., Sekiguchi K., Semple C.A., Seno S., Sessa L., Sheng Y., Shibata Y., Shimada H., Shimada K., Silva D., Sinclair B., Sperling S., Stupka E., Sugiura K., Sultana R., Takenaka Y., Taki K., Tammoja K., Tan S.L., Tang S., Taylor M.S., Tegner J., Teichmann S.A., Ueda H.R., van Nimwegen E., Verardo R., Wei C.L., Yagi K., Yamanishi H., Zabarovsky E., Zhu S., Zimmer A., Hide W., Bult C., Grimmond S.M., Teasdale R.D., Liu E.T., Brusic V., Quackenbush J., Wahlestedt C., Mattick J.S., Hume D.A., Kai C., Sasaki D., Tomaru Y., Fukuda S., Kanamori-Katayama M., Suzuki M., Aoki J., Arakawa T., Iida J., Imamura K., Itoh M., Kato T., Kawaji H., Kawagashira N., Kawashima T., Kojima M., Kondo S., Konno H., Nakano K., Ninomiya N., Nishio T., Okada M., Plessy C., Shibata K., Shiraki T., Suzuki S., Tagami M., Waki K., Watahiki A., Okamura-Oho Y., Suzuki H., Kawai J., Hayashizaki Y.
      Science 309:1559-1563(2005) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 1 AND 2), VARIANT GLN-GLY-PRO-GLY-ILE-166 INS.
      Strain: C57BL/6J.
      Tissue: Brain cortex, Embryo, Inner ear, Mammary gland and Testis.
    3. "Cloning of mouse full open reading frames in Gateway(R) system entry vector (pDONR201)."
      Ebert L., Muenstermann E., Schatten R., Henze S., Bohn E., Mollenhauer J., Wiemann S., Schick M., Korn B.
      Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1).
    4. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1), VARIANT GLN-GLY-PRO-GLY-ILE-166 INS.
      Tissue: Mammary tumor.

    Entry informationi

    Entry nameiCK001_MOUSE
    AccessioniPrimary (citable) accession number: Q9D131
    Secondary accession number(s): Q3TM17
    , Q3TYP3, Q4FK47, Q8K0A6, Q9D589, Q9JHT0
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: May 24, 2004
    Last sequence update: June 1, 2001
    Last modified: October 1, 2014
    This is version 76 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programChordata Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. MGD cross-references
      Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
    2. SIMILARITY comments
      Index of protein domains and families
    3. Uncharacterized protein families (UPF)
      List of uncharacterized protein family (UPF) entries

    External Data

    Dasty 3