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Protein

UPF0686 protein C11orf1 homolog

Gene
N/A
Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Names & Taxonomyi

Protein namesi
Recommended name:
UPF0686 protein C11orf1 homolog
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 9

Organism-specific databases

MGIiMGI:1915971. 1110032A03Rik.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000898301 – 166UPF0686 protein C11orf1 homologAdd BLAST166

Proteomic databases

PaxDbiQ9D131.
PRIDEiQ9D131.

PTM databases

iPTMnetiQ9D131.
PhosphoSitePlusiQ9D131.

Expressioni

Gene expression databases

BgeeiENSMUSG00000037971.
CleanExiMM_1110032A03RIK.
ExpressionAtlasiQ9D131. baseline and differential.
GenevisibleiQ9D131. MM.

Interactioni

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000041803.

Structurei

3D structure databases

ProteinModelPortaliQ9D131.
SMRiQ9D131.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the UPF0686 family.Curated

Phylogenomic databases

eggNOGiENOG410IVWW. Eukaryota.
ENOG411205M. LUCA.
GeneTreeiENSGT00390000002905.
HOVERGENiHBG050969.
InParanoidiQ9D131.
OMAiELDPPQY.
OrthoDBiEOG091G0ZSB.
PhylomeDBiQ9D131.
TreeFamiTF329225.

Family and domain databases

InterProiIPR009524. UPF0686.
[Graphical view]
PfamiPF06608. DUF1143. 1 hit.
[Graphical view]

Sequences (2)i

Sequence statusi: Complete.

This entry describes 2 isoformsi produced by alternative splicing. AlignAdd to basket

Isoform 1 (identifier: Q9D131-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide

        10         20         30         40         50
MAVSCSLNHS TYLQRQNLVC YLRNPHYGSL IYADGHGEVW TDWNDMSKFL
60 70 80 90 100
QYGWRCTTNE NSYSNRTLVG NWNQERYDLK NIVKPKPLPS QFGHAFETTY
110 120 130 140 150
DANYSRKKPQ STHRFKREPH WFPGHQPELD PPHYKCTAKS TYMTNYSEPQ
160
PTHYSCCVYD PSVSQS
Length:166
Mass (Da):19,527
Last modified:June 1, 2001 - v1
Checksum:iB299BEE9DB28E0EC
GO
Isoform 2 (identifier: Q9D131-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     1-13: MAVSCSLNHSTYL → MELPYRNRFYSLRCSSKSLYSPSSYTSII

Note: No experimental confirmation available.
Show »
Length:182
Mass (Da):21,551
Checksum:iAF5E65013478DA2B
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti8N → S in CAB96546 (PubMed:10873569).Curated1
Sequence conflicti8N → S in BAE34519 (PubMed:16141072).Curated1
Sequence conflicti14Q → K in CAB96546 (PubMed:10873569).Curated1
Sequence conflicti14Q → K in BAE34519 (PubMed:16141072).Curated1
Sequence conflicti158V → I in BC032012 (PubMed:15489334).Curated1

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Natural varianti166S → SQGPGI.2 Publications1

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Alternative sequenceiVSP_0275841 – 13MAVSC…HSTYL → MELPYRNRFYSLRCSSKSLY SPSSYTSII in isoform 2. 1 PublicationAdd BLAST13

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AJ250230 mRNA. Translation: CAB96546.1.
AK004016 mRNA. Translation: BAB23127.1.
AK015671 mRNA. Translation: BAB29923.1.
AK043513 mRNA. Translation: BAC31564.1.
AK158460 mRNA. Translation: BAE34519.1.
AK166202 mRNA. Translation: BAE38625.1.
CT010205 mRNA. Translation: CAJ18413.1.
BC032012 mRNA. No translation available.
CCDSiCCDS23173.1. [Q9D131-1]
CCDS80996.1. [Q9D131-2]
RefSeqiNP_001298002.1. NM_001311073.1. [Q9D131-2]
NP_075972.2. NM_023483.3. [Q9D131-1]
UniGeneiMm.171374.
Mm.432356.

Genome annotation databases

EnsembliENSMUST00000042468; ENSMUSP00000041803; ENSMUSG00000037971. [Q9D131-1]
ENSMUST00000042576; ENSMUSP00000046890; ENSMUSG00000037971. [Q9D131-2]
GeneIDi68721.
KEGGimmu:68721.
UCSCiuc009pko.1. mouse. [Q9D131-2]
uc009pkp.1. mouse. [Q9D131-1]

Keywords - Coding sequence diversityi

Alternative splicing, Polymorphism

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AJ250230 mRNA. Translation: CAB96546.1.
AK004016 mRNA. Translation: BAB23127.1.
AK015671 mRNA. Translation: BAB29923.1.
AK043513 mRNA. Translation: BAC31564.1.
AK158460 mRNA. Translation: BAE34519.1.
AK166202 mRNA. Translation: BAE38625.1.
CT010205 mRNA. Translation: CAJ18413.1.
BC032012 mRNA. No translation available.
CCDSiCCDS23173.1. [Q9D131-1]
CCDS80996.1. [Q9D131-2]
RefSeqiNP_001298002.1. NM_001311073.1. [Q9D131-2]
NP_075972.2. NM_023483.3. [Q9D131-1]
UniGeneiMm.171374.
Mm.432356.

3D structure databases

ProteinModelPortaliQ9D131.
SMRiQ9D131.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000041803.

PTM databases

iPTMnetiQ9D131.
PhosphoSitePlusiQ9D131.

Proteomic databases

PaxDbiQ9D131.
PRIDEiQ9D131.

Protocols and materials databases

DNASUi68721.
Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000042468; ENSMUSP00000041803; ENSMUSG00000037971. [Q9D131-1]
ENSMUST00000042576; ENSMUSP00000046890; ENSMUSG00000037971. [Q9D131-2]
GeneIDi68721.
KEGGimmu:68721.
UCSCiuc009pko.1. mouse. [Q9D131-2]
uc009pkp.1. mouse. [Q9D131-1]

Organism-specific databases

MGIiMGI:1915971. 1110032A03Rik.

Phylogenomic databases

eggNOGiENOG410IVWW. Eukaryota.
ENOG411205M. LUCA.
GeneTreeiENSGT00390000002905.
HOVERGENiHBG050969.
InParanoidiQ9D131.
OMAiELDPPQY.
OrthoDBiEOG091G0ZSB.
PhylomeDBiQ9D131.
TreeFamiTF329225.

Miscellaneous databases

PROiQ9D131.

Gene expression databases

BgeeiENSMUSG00000037971.
CleanExiMM_1110032A03RIK.
ExpressionAtlasiQ9D131. baseline and differential.
GenevisibleiQ9D131. MM.

Family and domain databases

InterProiIPR009524. UPF0686.
[Graphical view]
PfamiPF06608. DUF1143. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiCK001_MOUSE
AccessioniPrimary (citable) accession number: Q9D131
Secondary accession number(s): Q3TM17
, Q3TYP3, Q4FK47, Q8K0A6, Q9D589, Q9JHT0
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 24, 2004
Last sequence update: June 1, 2001
Last modified: November 2, 2016
This is version 88 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
  2. SIMILARITY comments
    Index of protein domains and families
  3. Uncharacterized protein families (UPF)
    List of uncharacterized protein family (UPF) entries

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.