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Protein

39S ribosomal protein L52, mitochondrial

Gene

Mrpl52

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Ribonucleoprotein, Ribosomal protein

Enzyme and pathway databases

ReactomeiR-MMU-5389840. Mitochondrial translation elongation.
R-MMU-5419276. Mitochondrial translation termination.

Names & Taxonomyi

Protein namesi
Recommended name:
39S ribosomal protein L52, mitochondrial
Short name:
L52mt
Short name:
MRP-L52
Gene namesi
Name:Mrpl52
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 14

Organism-specific databases

MGIiMGI:1916086. Mrpl52.

Subcellular locationi

  • Mitochondrion By similarity

GO - Cellular componenti

  • mitochondrial large ribosomal subunit Source: UniProtKB
  • mitochondrion Source: MGI
Complete GO annotation...

Keywords - Cellular componenti

Mitochondrion

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transit peptidei1 – 22MitochondrionSequence analysisAdd BLAST22
ChainiPRO_000027309423 – 12139S ribosomal protein L52, mitochondrialAdd BLAST99

Proteomic databases

EPDiQ9D0Y8.
PaxDbiQ9D0Y8.
PeptideAtlasiQ9D0Y8.
PRIDEiQ9D0Y8.

PTM databases

iPTMnetiQ9D0Y8.
PhosphoSitePlusiQ9D0Y8.

Expressioni

Gene expression databases

BgeeiENSMUSG00000010406.
CleanExiMM_MRPL52.
ExpressionAtlasiQ9D0Y8. baseline and differential.
GenevisibleiQ9D0Y8. MM.

Interactioni

Subunit structurei

Component of the mitochondrial ribosome large subunit (39S) which comprises a 16S rRNA and about 50 distinct proteins.By similarity

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000010550.

Structurei

3D structure databases

ProteinModelPortaliQ9D0Y8.
SMRiQ9D0Y8.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Keywords - Domaini

Transit peptide

Phylogenomic databases

eggNOGiENOG410J2WG. Eukaryota.
ENOG4111XV4. LUCA.
GeneTreeiENSGT00390000005763.
HOGENOMiHOG000293349.
HOVERGENiHBG093902.
InParanoidiQ9D0Y8.
KOiK17433.
OMAiWQLRQQE.
OrthoDBiEOG091G0YE9.
PhylomeDBiQ9D0Y8.
TreeFamiTF323872.

Sequences (2)i

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

This entry describes 2 isoformsi produced by alternative splicing. AlignAdd to basket

Isoform 1 (identifier: Q9D0Y8-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide

        10         20         30         40         50
MAALGTWLSS VRRLHCSVVA RAGGQWRLQQ GLAANPSGYG PLTELPDWSF
60 70 80 90 100
ADGRPAPPMK GQLRRKAQRE KLARRVVLLT QEMDAGIQAW KLRQQKLQEE
110 120
RKKEHDLKPK GTLLRSPLPN Q
Length:121
Mass (Da):13,658
Last modified:June 1, 2001 - v1
Checksum:iC024F28F8A5B016A
GO
Isoform 2 (identifier: Q9D0Y8-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     1-58: Missing.

Note: No experimental confirmation available.
Show »
Length:63
Mass (Da):7,501
Checksum:i0DD3383DCE9B5964
GO

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Alternative sequenceiVSP_0224761 – 58Missing in isoform 2. 1 PublicationAdd BLAST58

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK004194 mRNA. Translation: BAB23216.1.
AK150806 mRNA. Translation: BAE29869.1.
AK151615 mRNA. Translation: BAE30552.1.
AK152876 mRNA. Translation: BAE31561.1.
AK164629 mRNA. Translation: BAE37850.1.
BC028522 mRNA. Translation: AAH28522.1.
BC060043 mRNA. Translation: AAH60043.1.
CCDSiCCDS27088.1. [Q9D0Y8-1]
RefSeqiNP_081127.1. NM_026851.2. [Q9D0Y8-1]
UniGeneiMm.248163.

Genome annotation databases

EnsembliENSMUST00000010550; ENSMUSP00000010550; ENSMUSG00000010406. [Q9D0Y8-1]
ENSMUST00000199195; ENSMUSP00000142555; ENSMUSG00000010406. [Q9D0Y8-2]
GeneIDi68836.
KEGGimmu:68836.
UCSCiuc007tvz.1. mouse. [Q9D0Y8-1]

Keywords - Coding sequence diversityi

Alternative splicing

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK004194 mRNA. Translation: BAB23216.1.
AK150806 mRNA. Translation: BAE29869.1.
AK151615 mRNA. Translation: BAE30552.1.
AK152876 mRNA. Translation: BAE31561.1.
AK164629 mRNA. Translation: BAE37850.1.
BC028522 mRNA. Translation: AAH28522.1.
BC060043 mRNA. Translation: AAH60043.1.
CCDSiCCDS27088.1. [Q9D0Y8-1]
RefSeqiNP_081127.1. NM_026851.2. [Q9D0Y8-1]
UniGeneiMm.248163.

3D structure databases

ProteinModelPortaliQ9D0Y8.
SMRiQ9D0Y8.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000010550.

PTM databases

iPTMnetiQ9D0Y8.
PhosphoSitePlusiQ9D0Y8.

Proteomic databases

EPDiQ9D0Y8.
PaxDbiQ9D0Y8.
PeptideAtlasiQ9D0Y8.
PRIDEiQ9D0Y8.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000010550; ENSMUSP00000010550; ENSMUSG00000010406. [Q9D0Y8-1]
ENSMUST00000199195; ENSMUSP00000142555; ENSMUSG00000010406. [Q9D0Y8-2]
GeneIDi68836.
KEGGimmu:68836.
UCSCiuc007tvz.1. mouse. [Q9D0Y8-1]

Organism-specific databases

CTDi122704.
MGIiMGI:1916086. Mrpl52.

Phylogenomic databases

eggNOGiENOG410J2WG. Eukaryota.
ENOG4111XV4. LUCA.
GeneTreeiENSGT00390000005763.
HOGENOMiHOG000293349.
HOVERGENiHBG093902.
InParanoidiQ9D0Y8.
KOiK17433.
OMAiWQLRQQE.
OrthoDBiEOG091G0YE9.
PhylomeDBiQ9D0Y8.
TreeFamiTF323872.

Enzyme and pathway databases

ReactomeiR-MMU-5389840. Mitochondrial translation elongation.
R-MMU-5419276. Mitochondrial translation termination.

Miscellaneous databases

PROiQ9D0Y8.
SOURCEiSearch...

Gene expression databases

BgeeiENSMUSG00000010406.
CleanExiMM_MRPL52.
ExpressionAtlasiQ9D0Y8. baseline and differential.
GenevisibleiQ9D0Y8. MM.

Family and domain databases

ProtoNetiSearch...

Entry informationi

Entry nameiRM52_MOUSE
AccessioniPrimary (citable) accession number: Q9D0Y8
Secondary accession number(s): Q6PAU6
Entry historyi
Integrated into UniProtKB/Swiss-Prot: January 23, 2007
Last sequence update: June 1, 2001
Last modified: November 30, 2016
This is version 93 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.