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Protein

Transcription elongation factor A protein-like 8

Gene

Tceal8

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

May be involved in transcriptional regulation.

GO - Biological processi

Complete GO annotation...

Keywords - Biological processi

Transcription, Transcription regulation

Names & Taxonomyi

Protein namesi
Recommended name:
Transcription elongation factor A protein-like 8
Short name:
TCEA-like protein 8
Alternative name(s):
Transcription elongation factor S-II protein-like 8
Gene namesi
Name:Tceal8
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome X

Organism-specific databases

MGIiMGI:1913934. Tceal8.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 117117Transcription elongation factor A protein-like 8PRO_0000239217Add
BLAST

Proteomic databases

MaxQBiQ9CZY2.
PaxDbiQ9CZY2.
PRIDEiQ9CZY2.

PTM databases

PhosphoSiteiQ9CZY2.

Expressioni

Gene expression databases

BgeeiQ9CZY2.
CleanExiMM_TCEAL8.
ExpressionAtlasiQ9CZY2. baseline and differential.
GenevisibleiQ9CZY2. MM.

Interactioni

Protein-protein interaction databases

BioGridi211644. 1 interaction.
STRINGi10090.ENSMUSP00000056189.

Family & Domainsi

Coiled coil

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Coiled coili73 – 10028Sequence analysisAdd
BLAST

Sequence similaritiesi

Belongs to the TFS-II family. TFA subfamily.Curated

Keywords - Domaini

Coiled coil

Phylogenomic databases

eggNOGiENOG410JBTZ. Eukaryota.
ENOG4111DNR. LUCA.
GeneTreeiENSGT00730000111091.
HOGENOMiHOG000231343.
HOVERGENiHBG098559.
InParanoidiQ9CZY2.
OMAiSCDENEG.
OrthoDBiEOG7G4QH8.
PhylomeDBiQ9CZY2.

Family and domain databases

InterProiIPR021156. TF_A-like/BEX-like.
[Graphical view]
PfamiPF04538. BEX. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q9CZY2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MQKSCDENEG TPQNTPKADE GHPSEDPPQQ AGETLQASGE NVREETEGSH
60 70 80 90 100
RGEPAEPSPE PKEDTPARHL NPEEVIRGVD ELERLREEIR RVRNKFVLMH
110
WKQRHSRSRP YPVCFRP
Length:117
Mass (Da):13,472
Last modified:June 1, 2001 - v1
Checksum:i16245D8D6006CA22
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sequence conflicti111 – 1111Y → S in BAB29366 (PubMed:16141072).Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK012030 mRNA. Translation: BAB27984.1.
AK014459 mRNA. Translation: BAB29366.1.
AK137039 mRNA. Translation: BAE23212.1.
AK156414 mRNA. Translation: BAE33705.1.
AL772180 Genomic DNA. Translation: CAM14660.1.
BC027269 mRNA. Translation: AAH27269.1.
CCDSiCCDS30415.1.
RefSeqiNP_001162050.1. NM_001168578.1.
NP_079979.2. NM_025703.3.
XP_011246057.1. XM_011247755.1.
UniGeneiMm.182094.

Genome annotation databases

EnsembliENSMUST00000060101; ENSMUSP00000056189; ENSMUSG00000051579.
ENSMUST00000163584; ENSMUSP00000129591; ENSMUSG00000051579.
GeneIDi66684.
KEGGimmu:66684.
UCSCiuc009uie.2. mouse.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK012030 mRNA. Translation: BAB27984.1.
AK014459 mRNA. Translation: BAB29366.1.
AK137039 mRNA. Translation: BAE23212.1.
AK156414 mRNA. Translation: BAE33705.1.
AL772180 Genomic DNA. Translation: CAM14660.1.
BC027269 mRNA. Translation: AAH27269.1.
CCDSiCCDS30415.1.
RefSeqiNP_001162050.1. NM_001168578.1.
NP_079979.2. NM_025703.3.
XP_011246057.1. XM_011247755.1.
UniGeneiMm.182094.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi211644. 1 interaction.
STRINGi10090.ENSMUSP00000056189.

PTM databases

PhosphoSiteiQ9CZY2.

Proteomic databases

MaxQBiQ9CZY2.
PaxDbiQ9CZY2.
PRIDEiQ9CZY2.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000060101; ENSMUSP00000056189; ENSMUSG00000051579.
ENSMUST00000163584; ENSMUSP00000129591; ENSMUSG00000051579.
GeneIDi66684.
KEGGimmu:66684.
UCSCiuc009uie.2. mouse.

Organism-specific databases

CTDi90843.
MGIiMGI:1913934. Tceal8.

Phylogenomic databases

eggNOGiENOG410JBTZ. Eukaryota.
ENOG4111DNR. LUCA.
GeneTreeiENSGT00730000111091.
HOGENOMiHOG000231343.
HOVERGENiHBG098559.
InParanoidiQ9CZY2.
OMAiSCDENEG.
OrthoDBiEOG7G4QH8.
PhylomeDBiQ9CZY2.

Miscellaneous databases

ChiTaRSiTceal8. mouse.
PROiQ9CZY2.
SOURCEiSearch...

Gene expression databases

BgeeiQ9CZY2.
CleanExiMM_TCEAL8.
ExpressionAtlasiQ9CZY2. baseline and differential.
GenevisibleiQ9CZY2. MM.

Family and domain databases

InterProiIPR021156. TF_A-like/BEX-like.
[Graphical view]
PfamiPF04538. BEX. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "The transcriptional landscape of the mammalian genome."
    Carninci P., Kasukawa T., Katayama S., Gough J., Frith M.C., Maeda N., Oyama R., Ravasi T., Lenhard B., Wells C., Kodzius R., Shimokawa K., Bajic V.B., Brenner S.E., Batalov S., Forrest A.R., Zavolan M., Davis M.J.
    , Wilming L.G., Aidinis V., Allen J.E., Ambesi-Impiombato A., Apweiler R., Aturaliya R.N., Bailey T.L., Bansal M., Baxter L., Beisel K.W., Bersano T., Bono H., Chalk A.M., Chiu K.P., Choudhary V., Christoffels A., Clutterbuck D.R., Crowe M.L., Dalla E., Dalrymple B.P., de Bono B., Della Gatta G., di Bernardo D., Down T., Engstrom P., Fagiolini M., Faulkner G., Fletcher C.F., Fukushima T., Furuno M., Futaki S., Gariboldi M., Georgii-Hemming P., Gingeras T.R., Gojobori T., Green R.E., Gustincich S., Harbers M., Hayashi Y., Hensch T.K., Hirokawa N., Hill D., Huminiecki L., Iacono M., Ikeo K., Iwama A., Ishikawa T., Jakt M., Kanapin A., Katoh M., Kawasawa Y., Kelso J., Kitamura H., Kitano H., Kollias G., Krishnan S.P., Kruger A., Kummerfeld S.K., Kurochkin I.V., Lareau L.F., Lazarevic D., Lipovich L., Liu J., Liuni S., McWilliam S., Madan Babu M., Madera M., Marchionni L., Matsuda H., Matsuzawa S., Miki H., Mignone F., Miyake S., Morris K., Mottagui-Tabar S., Mulder N., Nakano N., Nakauchi H., Ng P., Nilsson R., Nishiguchi S., Nishikawa S., Nori F., Ohara O., Okazaki Y., Orlando V., Pang K.C., Pavan W.J., Pavesi G., Pesole G., Petrovsky N., Piazza S., Reed J., Reid J.F., Ring B.Z., Ringwald M., Rost B., Ruan Y., Salzberg S.L., Sandelin A., Schneider C., Schoenbach C., Sekiguchi K., Semple C.A., Seno S., Sessa L., Sheng Y., Shibata Y., Shimada H., Shimada K., Silva D., Sinclair B., Sperling S., Stupka E., Sugiura K., Sultana R., Takenaka Y., Taki K., Tammoja K., Tan S.L., Tang S., Taylor M.S., Tegner J., Teichmann S.A., Ueda H.R., van Nimwegen E., Verardo R., Wei C.L., Yagi K., Yamanishi H., Zabarovsky E., Zhu S., Zimmer A., Hide W., Bult C., Grimmond S.M., Teasdale R.D., Liu E.T., Brusic V., Quackenbush J., Wahlestedt C., Mattick J.S., Hume D.A., Kai C., Sasaki D., Tomaru Y., Fukuda S., Kanamori-Katayama M., Suzuki M., Aoki J., Arakawa T., Iida J., Imamura K., Itoh M., Kato T., Kawaji H., Kawagashira N., Kawashima T., Kojima M., Kondo S., Konno H., Nakano K., Ninomiya N., Nishio T., Okada M., Plessy C., Shibata K., Shiraki T., Suzuki S., Tagami M., Waki K., Watahiki A., Okamura-Oho Y., Suzuki H., Kawai J., Hayashizaki Y.
    Science 309:1559-1563(2005) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Strain: C57BL/6J and NOD.
    Tissue: Embryo and Spleen.
  2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: C57BL/6J.
  3. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Strain: Czech II.
    Tissue: Mammary tumor.

Entry informationi

Entry nameiTCAL8_MOUSE
AccessioniPrimary (citable) accession number: Q9CZY2
Secondary accession number(s): A2AJR7, Q9CYP9
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 30, 2006
Last sequence update: June 1, 2001
Last modified: June 8, 2016
This is version 99 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.