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Q9CZR4

- CKLF8_MOUSE

UniProt

Q9CZR4 - CKLF8_MOUSE

Protein

CKLF-like MARVEL transmembrane domain-containing protein 8

Gene

Cmtm8

Organism
Mus musculus (Mouse)
Status
Reviewed - Annotation score: 2 out of 5- Experimental evidence at transcript leveli
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    • History
      Entry version 82 (01 Oct 2014)
      Sequence version 1 (01 Jun 2001)
      Previous versions | rss
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    Functioni

    GO - Biological processi

    1. chemotaxis Source: UniProtKB-KW

    Keywords - Molecular functioni

    Cytokine

    Keywords - Biological processi

    Chemotaxis

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    CKLF-like MARVEL transmembrane domain-containing protein 8
    Alternative name(s):
    Chemokine-like factor superfamily member 8
    Gene namesi
    Name:Cmtm8
    Synonyms:Cklfsf8
    OrganismiMus musculus (Mouse)
    Taxonomic identifieri10090 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
    ProteomesiUP000000589: Chromosome 9

    Organism-specific databases

    MGIiMGI:2447167. Cmtm8.

    Subcellular locationi

    GO - Cellular componenti

    1. extracellular space Source: UniProtKB-KW
    2. integral component of membrane Source: UniProtKB-KW

    Keywords - Cellular componenti

    Membrane

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 173173CKLF-like MARVEL transmembrane domain-containing protein 8PRO_0000186113Add
    BLAST

    Proteomic databases

    PRIDEiQ9CZR4.

    PTM databases

    PhosphoSiteiQ9CZR4.

    Expressioni

    Gene expression databases

    BgeeiQ9CZR4.
    GenevestigatoriQ9CZR4.

    Interactioni

    Protein-protein interaction databases

    STRINGi10090.ENSMUSP00000043706.

    Structurei

    Transmembrane

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Transmembranei41 – 6121HelicalSequence AnalysisAdd
    BLAST
    Transmembranei70 – 9021HelicalSequence AnalysisAdd
    BLAST
    Transmembranei105 – 12521HelicalSequence AnalysisAdd
    BLAST
    Transmembranei147 – 16721HelicalSequence AnalysisAdd
    BLAST

    Family & Domainsi

    Domains and Repeats

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Domaini36 – 168133MARVELPROSITE-ProRule annotationAdd
    BLAST

    Sequence similaritiesi

    Belongs to the chemokine-like factor family.Curated
    Contains 1 MARVEL domain.PROSITE-ProRule annotation

    Keywords - Domaini

    Transmembrane, Transmembrane helix

    Phylogenomic databases

    eggNOGiNOG270058.
    GeneTreeiENSGT00730000110954.
    HOGENOMiHOG000247057.
    HOVERGENiHBG108271.
    InParanoidiQ9CZR4.
    OMAiWYLLEEL.
    OrthoDBiEOG74TX1B.
    PhylomeDBiQ9CZR4.
    TreeFamiTF316174.

    Family and domain databases

    InterProiIPR013295. MAL.
    IPR008253. Marvel.
    [Graphical view]
    PfamiPF01284. MARVEL. 1 hit.
    [Graphical view]
    PRINTSiPR01884. MALPROTEIN.
    PROSITEiPS51225. MARVEL. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q9CZR4-1 [UniParc]FASTAAdd to Basket

    « Hide

    MEEQQRARSH TVTTTTSSFA ENFSTTSSSF AYDREFLRTP PGLLIVAEIV    50
    LGLLVWTLIA GTEYFRVPAF GWVMFVAVFY WVLTVFFLIV YITLTYTRIP 100
    QVPWTTVGLC FNGSAFVLYF SAAIVDASSV SPEKEGHNFN SWAASSFFAF 150
    LVTICYAGNT YFSFIAWRSR TAQ 173
    Length:173
    Mass (Da):19,527
    Last modified:June 1, 2001 - v1
    Checksum:iB58E8E5C0E8539A1
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AY243513 mRNA. Translation: AAO89236.1.
    AK012262 mRNA. Translation: BAB28125.1.
    BC027554 mRNA. Translation: AAH27554.1.
    CCDSiCCDS23597.1.
    RefSeqiNP_081570.1. NM_027294.2.
    UniGeneiMm.150064.

    Genome annotation databases

    EnsembliENSMUST00000047013; ENSMUSP00000043706; ENSMUSG00000041012.
    GeneIDi70031.
    KEGGimmu:70031.
    UCSCiuc009ryg.1. mouse.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AY243513 mRNA. Translation: AAO89236.1 .
    AK012262 mRNA. Translation: BAB28125.1 .
    BC027554 mRNA. Translation: AAH27554.1 .
    CCDSi CCDS23597.1.
    RefSeqi NP_081570.1. NM_027294.2.
    UniGenei Mm.150064.

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 10090.ENSMUSP00000043706.

    PTM databases

    PhosphoSitei Q9CZR4.

    Proteomic databases

    PRIDEi Q9CZR4.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    Ensembli ENSMUST00000047013 ; ENSMUSP00000043706 ; ENSMUSG00000041012 .
    GeneIDi 70031.
    KEGGi mmu:70031.
    UCSCi uc009ryg.1. mouse.

    Organism-specific databases

    CTDi 152189.
    MGIi MGI:2447167. Cmtm8.

    Phylogenomic databases

    eggNOGi NOG270058.
    GeneTreei ENSGT00730000110954.
    HOGENOMi HOG000247057.
    HOVERGENi HBG108271.
    InParanoidi Q9CZR4.
    OMAi WYLLEEL.
    OrthoDBi EOG74TX1B.
    PhylomeDBi Q9CZR4.
    TreeFami TF316174.

    Miscellaneous databases

    NextBioi 330865.
    PROi Q9CZR4.
    SOURCEi Search...

    Gene expression databases

    Bgeei Q9CZR4.
    Genevestigatori Q9CZR4.

    Family and domain databases

    InterProi IPR013295. MAL.
    IPR008253. Marvel.
    [Graphical view ]
    Pfami PF01284. MARVEL. 1 hit.
    [Graphical view ]
    PRINTSi PR01884. MALPROTEIN.
    PROSITEi PS51225. MARVEL. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Ding P., Han W., Li T., Yang T., Shi S., Tan Y., Ma D.
      Submitted (FEB-2003) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE [MRNA].
      Tissue: Leukocyte.
    2. "The transcriptional landscape of the mammalian genome."
      Carninci P., Kasukawa T., Katayama S., Gough J., Frith M.C., Maeda N., Oyama R., Ravasi T., Lenhard B., Wells C., Kodzius R., Shimokawa K., Bajic V.B., Brenner S.E., Batalov S., Forrest A.R., Zavolan M., Davis M.J.
      , Wilming L.G., Aidinis V., Allen J.E., Ambesi-Impiombato A., Apweiler R., Aturaliya R.N., Bailey T.L., Bansal M., Baxter L., Beisel K.W., Bersano T., Bono H., Chalk A.M., Chiu K.P., Choudhary V., Christoffels A., Clutterbuck D.R., Crowe M.L., Dalla E., Dalrymple B.P., de Bono B., Della Gatta G., di Bernardo D., Down T., Engstrom P., Fagiolini M., Faulkner G., Fletcher C.F., Fukushima T., Furuno M., Futaki S., Gariboldi M., Georgii-Hemming P., Gingeras T.R., Gojobori T., Green R.E., Gustincich S., Harbers M., Hayashi Y., Hensch T.K., Hirokawa N., Hill D., Huminiecki L., Iacono M., Ikeo K., Iwama A., Ishikawa T., Jakt M., Kanapin A., Katoh M., Kawasawa Y., Kelso J., Kitamura H., Kitano H., Kollias G., Krishnan S.P., Kruger A., Kummerfeld S.K., Kurochkin I.V., Lareau L.F., Lazarevic D., Lipovich L., Liu J., Liuni S., McWilliam S., Madan Babu M., Madera M., Marchionni L., Matsuda H., Matsuzawa S., Miki H., Mignone F., Miyake S., Morris K., Mottagui-Tabar S., Mulder N., Nakano N., Nakauchi H., Ng P., Nilsson R., Nishiguchi S., Nishikawa S., Nori F., Ohara O., Okazaki Y., Orlando V., Pang K.C., Pavan W.J., Pavesi G., Pesole G., Petrovsky N., Piazza S., Reed J., Reid J.F., Ring B.Z., Ringwald M., Rost B., Ruan Y., Salzberg S.L., Sandelin A., Schneider C., Schoenbach C., Sekiguchi K., Semple C.A., Seno S., Sessa L., Sheng Y., Shibata Y., Shimada H., Shimada K., Silva D., Sinclair B., Sperling S., Stupka E., Sugiura K., Sultana R., Takenaka Y., Taki K., Tammoja K., Tan S.L., Tang S., Taylor M.S., Tegner J., Teichmann S.A., Ueda H.R., van Nimwegen E., Verardo R., Wei C.L., Yagi K., Yamanishi H., Zabarovsky E., Zhu S., Zimmer A., Hide W., Bult C., Grimmond S.M., Teasdale R.D., Liu E.T., Brusic V., Quackenbush J., Wahlestedt C., Mattick J.S., Hume D.A., Kai C., Sasaki D., Tomaru Y., Fukuda S., Kanamori-Katayama M., Suzuki M., Aoki J., Arakawa T., Iida J., Imamura K., Itoh M., Kato T., Kawaji H., Kawagashira N., Kawashima T., Kojima M., Kondo S., Konno H., Nakano K., Ninomiya N., Nishio T., Okada M., Plessy C., Shibata K., Shiraki T., Suzuki S., Tagami M., Waki K., Watahiki A., Okamura-Oho Y., Suzuki H., Kawai J., Hayashizaki Y.
      Science 309:1559-1563(2005) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
      Strain: C57BL/6J.
      Tissue: Embryo.
    3. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
      Tissue: Mammary gland.

    Entry informationi

    Entry nameiCKLF8_MOUSE
    AccessioniPrimary (citable) accession number: Q9CZR4
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: September 19, 2003
    Last sequence update: June 1, 2001
    Last modified: October 1, 2014
    This is version 82 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programChordata Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. MGD cross-references
      Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3