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Protein

60S ribosomal protein L15

Gene

Rpl15

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionRibonucleoprotein, Ribosomal protein

Names & Taxonomyi

Protein namesi
Recommended name:
60S ribosomal protein L15
Gene namesi
Name:Rpl15
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 14

Organism-specific databases

MGIiMGI:1913730 Rpl15

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Initiator methionineiRemovedBy similarity
ChainiPRO_00001275282 – 20460S ribosomal protein L15Add BLAST203

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Lipidationi2N-myristoyl glycineBy similarity1
Modified residuei34PhosphoserineBy similarity1
Cross-linki83Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)By similarity
Modified residuei97PhosphoserineBy similarity1
Modified residuei100PhosphoserineBy similarity1

Keywords - PTMi

Isopeptide bond, Lipoprotein, Myristate, Phosphoprotein, Ubl conjugation

Proteomic databases

EPDiQ9CZM2
MaxQBiQ9CZM2
PaxDbiQ9CZM2
PRIDEiQ9CZM2

PTM databases

iPTMnetiQ9CZM2
PhosphoSitePlusiQ9CZM2
SwissPalmiQ9CZM2

Expressioni

Gene expression databases

BgeeiENSMUSG00000012405
CleanExiMM_RPL15
ExpressionAtlasiQ9CZM2 baseline and differential
GenevisibleiQ9CZM2 MM

Interactioni

Subunit structurei

Interacts with IFIT1 (via TPR repeats 1-4).By similarity

GO - Molecular functioni

Protein-protein interaction databases

BioGridi211504, 5 interactors
CORUMiQ9CZM2
IntActiQ9CZM2, 8 interactors
MINTiQ9CZM2
STRINGi10090.ENSMUSP00000078388

Structurei

3D structure databases

ProteinModelPortaliQ9CZM2
SMRiQ9CZM2
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiKOG1678 Eukaryota
COG1632 LUCA
GeneTreeiENSGT00910000144184
HOGENOMiHOG000229584
HOVERGENiHBG000443
InParanoidiQ9CZM2
KOiK02877
OMAiYWVAQDS
OrthoDBiEOG091G0LFF
PhylomeDBiQ9CZM2
TreeFamiTF300050

Family and domain databases

Gene3Di3.40.1120.10, 1 hit
InterProiView protein in InterPro
IPR024794 Rbsml_L15e_core_dom_sf
IPR000439 Ribosomal_L15e
IPR020925 Ribosomal_L15e_CS
IPR012678 Ribosomal_L23/L15e_core_dom_sf
PANTHERiPTHR11847 PTHR11847, 1 hit
PfamiView protein in Pfam
PF00827 Ribosomal_L15e, 1 hit
SMARTiView protein in SMART
SM01384 Ribosomal_L15e, 1 hit
SUPFAMiSSF54189 SSF54189, 1 hit
PROSITEiView protein in PROSITE
PS01194 RIBOSOMAL_L15E, 1 hit

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q9CZM2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGAYKYIQEL WRKKQSDVMR FLLRVRCWQY RQLSALHRAP RPTRPDKARR
60 70 80 90 100
LGYKAKQGYV IYRIRVRRGG RKRPVPKGAT YGKPVHHGVN QLKFARSLQS
110 120 130 140 150
VAEERAGRHC GALRVLNSYW VGEDSTYKFF EVILIDPFHK AIRRNPDTQW
160 170 180 190 200
ITKPVHKHRE MRGLTSAGRK SRGLGKGHKF HHTIGGSRRA AWRRRNTLQL

HRYR
Length:204
Mass (Da):24,146
Last modified:January 23, 2007 - v4
Checksum:iA6E3AD1A76C9506F
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti194R → G in BAB27107 (PubMed:16141072).Curated1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK002234 mRNA Translation: BAB21952.1
AK010319 mRNA Translation: BAB26850.1
AK010674 mRNA Translation: BAB27107.1
AK010916 mRNA Translation: BAB27266.1
AK010931 mRNA Translation: BAB27275.1
AK012025 mRNA Translation: BAB27981.1
BC079842 mRNA Translation: AAH79842.1
BC081441 mRNA Translation: AAH81441.1
BC081442 mRNA Translation: AAH81442.1
CCDSiCCDS36812.1
RefSeqiNP_079862.1, NM_025586.3
XP_006518143.1, XM_006518080.3
XP_006518144.1, XM_006518081.3
UniGeneiMm.2050
Mm.387909

Genome annotation databases

EnsembliENSMUST00000079419; ENSMUSP00000078388; ENSMUSG00000012405
ENSMUST00000080281; ENSMUSP00000079163; ENSMUSG00000012405
ENSMUST00000100799; ENSMUSP00000098362; ENSMUSG00000012405
ENSMUST00000112598; ENSMUSP00000108217; ENSMUSG00000012405
GeneIDi66480
KEGGimmu:66480
UCSCiuc007shr.1 mouse

Similar proteinsi

Entry informationi

Entry nameiRL15_MOUSE
AccessioniPrimary (citable) accession number: Q9CZM2
Secondary accession number(s): Q9CWI5
Entry historyiIntegrated into UniProtKB/Swiss-Prot: July 11, 2001
Last sequence update: January 23, 2007
Last modified: February 28, 2018
This is version 139 of the entry and version 4 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome
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Main funding by: National Institutes of Health