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Q9CZK7

- Q9CZK7_MOUSE

UniProt

Q9CZK7 - Q9CZK7_MOUSE

Protein
Submitted name:

Putative uncharacterized protein

Gene

Pax3

Organism
Mus musculus (Mouse)
Status
Unreviewed - Annotation score: 5 out of 5- Experimental evidence at transcript leveli
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    • History
      Entry version 109 (01 Oct 2014)
      Sequence version 2 (01 Mar 2003)
      Previous versions | rss
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    Functioni

    GO - Molecular functioni

    1. chromatin binding Source: MGI
    2. protein binding Source: MGI
    3. RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity Source: MGI
    4. sequence-specific DNA binding Source: MGI
    5. sequence-specific DNA binding transcription factor activity Source: MGI

    GO - Biological processi

    1. cell migration Source: MGI
    2. cell proliferation Source: MGI
    3. developmental pigmentation Source: MGI
    4. heart development Source: MGI
    5. mammary gland specification Source: MGI
    6. muscle organ development Source: MGI
    7. negative regulation of transcription from RNA polymerase II promoter Source: MGI
    8. neural crest cell migration Source: MGI
    9. neural tube closure Source: MGI
    10. neural tube development Source: MGI
    11. neuron fate commitment Source: MGI
    12. positive regulation of cell proliferation Source: MGI
    13. positive regulation of transcription, DNA-templated Source: MGI
    14. positive regulation of transcription from RNA polymerase II promoter Source: MGI
    15. regulation of somitogenesis Source: MGI
    16. spinal cord association neuron differentiation Source: MGI
    17. transcription from RNA polymerase II promoter Source: GOC

    Keywords - Molecular functioni

    Developmental proteinUniRule annotationSAAS annotation

    Keywords - Biological processi

    Transcription, Transcription regulationUniRule annotationSAAS annotation

    Keywords - Ligandi

    DNA-bindingUniRule annotationSAAS annotation

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    Putative uncharacterized proteinImported
    Gene namesi
    Name:Pax3Imported
    OrganismiMus musculus (Mouse)Imported
    Taxonomic identifieri10090 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus

    Organism-specific databases

    MGIiMGI:97487. Pax3.

    Subcellular locationi

    Nucleus UniRule annotationSAAS annotation

    GO - Cellular componenti

    1. nucleus Source: MGI
    2. transcription factor complex Source: MGI

    Keywords - Cellular componenti

    NucleusUniRule annotationSAAS annotation

    PTM / Processingi

    Proteomic databases

    PRIDEiQ9CZK7.

    Expressioni

    Gene expression databases

    GenevestigatoriQ9CZK7.

    Structurei

    3D structure databases

    ProteinModelPortaliQ9CZK7.
    SMRiQ9CZK7. Positions 39-162, 222-281.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Contains 1 paired domain.UniRule annotation
    Contains paired domain.SAAS annotation

    Keywords - Domaini

    HomeoboxUniRule annotation, Paired boxUniRule annotationSAAS annotation

    Phylogenomic databases

    HOGENOMiHOG000230939.
    HOVERGENiHBG009115.
    InParanoidiQ9CZK7.

    Family and domain databases

    Gene3Di1.10.10.10. 2 hits.
    1.10.10.60. 1 hit.
    InterProiIPR017970. Homeobox_CS.
    IPR001356. Homeobox_dom.
    IPR009057. Homeodomain-like.
    IPR001523. Paired_dom.
    IPR022106. Pax7.
    IPR011991. WHTH_DNA-bd_dom.
    [Graphical view]
    PfamiPF00046. Homeobox. 1 hit.
    PF00292. PAX. 1 hit.
    PF12360. Pax7. 1 hit.
    [Graphical view]
    PRINTSiPR00027. PAIREDBOX.
    SMARTiSM00389. HOX. 1 hit.
    SM00351. PAX. 1 hit.
    [Graphical view]
    SUPFAMiSSF46689. SSF46689. 2 hits.
    PROSITEiPS00027. HOMEOBOX_1. 1 hit.
    PS50071. HOMEOBOX_2. 1 hit.
    PS00034. PAIRED_1. 1 hit.
    PS51057. PAIRED_2. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q9CZK7-1 [UniParc]FASTAAdd to Basket

    « Hide

    MAPRMTTLAG AVPRMMRPGP GQNYPRSGFP LEVSTPLGQG RVNQLGGVFI    50
    NGRPLPNHIR HKIVEMAHHG IRPCVISRQL RVSHGCVSKI LCRYQETGSI 100
    RPGAIGGSKP KQVTTPDVEK KIEEYKRENP GMFSWEIRDK LLKDAVCDRN 150
    TVPSVSSISR ILRSKFGKGE EEEADLERKE AEESEKKAKH SIDGILSERA 200
    SAPQSDEGSD IDSEPDLPLK RKQRGSRTTF TAEQLEELER AFERTHYPDI 250
    YTREELAQRA KLTEARVQVW FSNRRARWRK QAGANQLMAF NHLIPGGFPP 300
    TAMPTLPTYQ LSETSYQPTS IPQAVSDPSS TVHRPQPLPP STVHQSTIPS 350
    NADSSSAYCL PSTRHGFSSY TDSFVPPSGP SNPMNPTIGN GLSPQVMGLL 400
    TNHGGVPHQP QTDYALSPLT GGLEPTTTVS ASCSQRLEHM KNVDSLPTSQ 450
    PYCPPTYSTA GYSMDPVTGY QYGQYGQSAF HYLKPDIA 488
    Length:488
    Mass (Da):53,802
    Last modified:March 1, 2003 - v2
    Checksum:iAA071E949F61EFA6
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AK012493 mRNA. Translation: BAB28278.2.
    UniGeneiMm.1371.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AK012493 mRNA. Translation: BAB28278.2 .
    UniGenei Mm.1371.

    3D structure databases

    ProteinModelPortali Q9CZK7.
    SMRi Q9CZK7. Positions 39-162, 222-281.
    ModBasei Search...
    MobiDBi Search...

    Proteomic databases

    PRIDEi Q9CZK7.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Organism-specific databases

    MGIi MGI:97487. Pax3.

    Phylogenomic databases

    HOGENOMi HOG000230939.
    HOVERGENi HBG009115.
    InParanoidi Q9CZK7.

    Miscellaneous databases

    ChiTaRSi PAX3. mouse.
    SOURCEi Search...

    Gene expression databases

    Genevestigatori Q9CZK7.

    Family and domain databases

    Gene3Di 1.10.10.10. 2 hits.
    1.10.10.60. 1 hit.
    InterProi IPR017970. Homeobox_CS.
    IPR001356. Homeobox_dom.
    IPR009057. Homeodomain-like.
    IPR001523. Paired_dom.
    IPR022106. Pax7.
    IPR011991. WHTH_DNA-bd_dom.
    [Graphical view ]
    Pfami PF00046. Homeobox. 1 hit.
    PF00292. PAX. 1 hit.
    PF12360. Pax7. 1 hit.
    [Graphical view ]
    PRINTSi PR00027. PAIREDBOX.
    SMARTi SM00389. HOX. 1 hit.
    SM00351. PAX. 1 hit.
    [Graphical view ]
    SUPFAMi SSF46689. SSF46689. 2 hits.
    PROSITEi PS00027. HOMEOBOX_1. 1 hit.
    PS50071. HOMEOBOX_2. 1 hit.
    PS00034. PAIRED_1. 1 hit.
    PS51057. PAIRED_2. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "High-efficiency full-length cDNA cloning."
      Carninci P., Hayashizaki Y.
      Methods Enzymol. 303:19-44(1999) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE.
      Strain: C57BL/6JImported.
      Tissue: Whole bodyImported.
    2. "Normalization and subtraction of cap-trapper-selected cDNAs to prepare full-length cDNA libraries for rapid discovery of new genes."
      Carninci P., Shibata Y., Hayatsu N., Sugahara Y., Shibata K., Itoh M., Konno H., Okazaki Y., Muramatsu M., Hayashizaki Y.
      Genome Res. 10:1617-1630(2000) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE.
      Strain: C57BL/6JImported.
      Tissue: Whole bodyImported.
    3. Cited for: NUCLEOTIDE SEQUENCE.
      Strain: C57BL/6JImported.
      Tissue: Whole bodyImported.
    4. Cited for: NUCLEOTIDE SEQUENCE.
      Strain: C57BL/6JImported.
      Tissue: Whole bodyImported.
    5. "Functional annotation of a full-length mouse cDNA collection."
      The RIKEN Genome Exploration Research Group Phase II Team and the FANTOM Consortium
      Nature 409:685-690(2001)
      Cited for: NUCLEOTIDE SEQUENCE.
      Strain: C57BL/6JImported.
      Tissue: Whole bodyImported.
    6. "Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs."
      The FANTOM Consortium and the RIKEN Genome Exploration Research Group Phase I and II Team
      Nature 420:563-573(2002)
      Cited for: NUCLEOTIDE SEQUENCE.
      Strain: C57BL/6JImported.
      Tissue: Whole bodyImported.
    7. "The Transcriptional Landscape of the Mammalian Genome."
      The FANTOM Consortium, Riken Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group)
      Science 309:1559-1563(2005)
      Cited for: NUCLEOTIDE SEQUENCE.
      Strain: C57BL/6JImported.
      Tissue: Whole bodyImported.
    8. Cited for: NUCLEOTIDE SEQUENCE.
      Strain: C57BL/6JImported.
      Tissue: Whole bodyImported.

    Entry informationi

    Entry nameiQ9CZK7_MOUSE
    AccessioniPrimary (citable) accession number: Q9CZK7
    Entry historyi
    Integrated into UniProtKB/TrEMBL: June 1, 2001
    Last sequence update: March 1, 2003
    Last modified: October 1, 2014
    This is version 109 of the entry and version 2 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)