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Q9CZK7

- Q9CZK7_MOUSE

UniProt

Q9CZK7 - Q9CZK7_MOUSE

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Protein
Submitted name:

Putative uncharacterized protein

Gene

Pax3

Organism
Mus musculus (Mouse)
Status
Unreviewed - Annotation score: 5 out of 5- Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

  1. chromatin binding Source: MGI
  2. RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity Source: MGI
  3. sequence-specific DNA binding Source: MGI
  4. sequence-specific DNA binding transcription factor activity Source: MGI

GO - Biological processi

  1. cell migration Source: MGI
  2. cell proliferation Source: MGI
  3. developmental pigmentation Source: MGI
  4. heart development Source: MGI
  5. mammary gland specification Source: MGI
  6. muscle organ development Source: MGI
  7. negative regulation of transcription from RNA polymerase II promoter Source: MGI
  8. neural crest cell migration Source: MGI
  9. neural tube closure Source: MGI
  10. neural tube development Source: MGI
  11. neuron fate commitment Source: MGI
  12. positive regulation of cell proliferation Source: MGI
  13. positive regulation of transcription, DNA-templated Source: MGI
  14. positive regulation of transcription from RNA polymerase II promoter Source: MGI
  15. regulation of somitogenesis Source: MGI
  16. spinal cord association neuron differentiation Source: MGI
  17. transcription from RNA polymerase II promoter Source: GOC
Complete GO annotation...

Keywords - Molecular functioni

Developmental proteinUniRule annotationSAAS annotation

Keywords - Biological processi

Transcription, Transcription regulationUniRule annotationSAAS annotation

Keywords - Ligandi

DNA-bindingUniRule annotationSAAS annotation

Names & Taxonomyi

Protein namesi
Submitted name:
Putative uncharacterized proteinImported
Gene namesi
Name:Pax3Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus

Organism-specific databases

MGIiMGI:97487. Pax3.

Subcellular locationi

Nucleus UniRule annotationSAAS annotation

GO - Cellular componenti

  1. nucleus Source: MGI
  2. transcription factor complex Source: MGI
Complete GO annotation...

Keywords - Cellular componenti

NucleusUniRule annotationSAAS annotation

PTM / Processingi

Proteomic databases

PRIDEiQ9CZK7.

Expressioni

Gene expression databases

GenevestigatoriQ9CZK7.

Structurei

3D structure databases

ProteinModelPortaliQ9CZK7.
SMRiQ9CZK7. Positions 39-162, 222-281.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Contains 1 paired domain.
Contains paired domain.SAAS annotation

Keywords - Domaini

HomeoboxUniRule annotation, Paired boxUniRule annotationSAAS annotation

Phylogenomic databases

HOGENOMiHOG000230939.
HOVERGENiHBG009115.

Family and domain databases

Gene3Di1.10.10.10. 2 hits.
1.10.10.60. 1 hit.
InterProiIPR017970. Homeobox_CS.
IPR001356. Homeobox_dom.
IPR009057. Homeodomain-like.
IPR001523. Paired_dom.
IPR022106. Pax7.
IPR011991. WHTH_DNA-bd_dom.
[Graphical view]
PfamiPF00046. Homeobox. 1 hit.
PF00292. PAX. 1 hit.
PF12360. Pax7. 1 hit.
[Graphical view]
PRINTSiPR00027. PAIREDBOX.
SMARTiSM00389. HOX. 1 hit.
SM00351. PAX. 1 hit.
[Graphical view]
SUPFAMiSSF46689. SSF46689. 2 hits.
PROSITEiPS00027. HOMEOBOX_1. 1 hit.
PS50071. HOMEOBOX_2. 1 hit.
PS00034. PAIRED_1. 1 hit.
PS51057. PAIRED_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q9CZK7-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MAPRMTTLAG AVPRMMRPGP GQNYPRSGFP LEVSTPLGQG RVNQLGGVFI
60 70 80 90 100
NGRPLPNHIR HKIVEMAHHG IRPCVISRQL RVSHGCVSKI LCRYQETGSI
110 120 130 140 150
RPGAIGGSKP KQVTTPDVEK KIEEYKRENP GMFSWEIRDK LLKDAVCDRN
160 170 180 190 200
TVPSVSSISR ILRSKFGKGE EEEADLERKE AEESEKKAKH SIDGILSERA
210 220 230 240 250
SAPQSDEGSD IDSEPDLPLK RKQRGSRTTF TAEQLEELER AFERTHYPDI
260 270 280 290 300
YTREELAQRA KLTEARVQVW FSNRRARWRK QAGANQLMAF NHLIPGGFPP
310 320 330 340 350
TAMPTLPTYQ LSETSYQPTS IPQAVSDPSS TVHRPQPLPP STVHQSTIPS
360 370 380 390 400
NADSSSAYCL PSTRHGFSSY TDSFVPPSGP SNPMNPTIGN GLSPQVMGLL
410 420 430 440 450
TNHGGVPHQP QTDYALSPLT GGLEPTTTVS ASCSQRLEHM KNVDSLPTSQ
460 470 480
PYCPPTYSTA GYSMDPVTGY QYGQYGQSAF HYLKPDIA
Length:488
Mass (Da):53,802
Last modified:March 1, 2003 - v2
Checksum:iAA071E949F61EFA6
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK012493 mRNA. Translation: BAB28278.2.
UniGeneiMm.1371.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK012493 mRNA. Translation: BAB28278.2 .
UniGenei Mm.1371.

3D structure databases

ProteinModelPortali Q9CZK7.
SMRi Q9CZK7. Positions 39-162, 222-281.
ModBasei Search...
MobiDBi Search...

Proteomic databases

PRIDEi Q9CZK7.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Organism-specific databases

MGIi MGI:97487. Pax3.

Phylogenomic databases

HOGENOMi HOG000230939.
HOVERGENi HBG009115.

Miscellaneous databases

ChiTaRSi Pax3. mouse.
SOURCEi Search...

Gene expression databases

Genevestigatori Q9CZK7.

Family and domain databases

Gene3Di 1.10.10.10. 2 hits.
1.10.10.60. 1 hit.
InterProi IPR017970. Homeobox_CS.
IPR001356. Homeobox_dom.
IPR009057. Homeodomain-like.
IPR001523. Paired_dom.
IPR022106. Pax7.
IPR011991. WHTH_DNA-bd_dom.
[Graphical view ]
Pfami PF00046. Homeobox. 1 hit.
PF00292. PAX. 1 hit.
PF12360. Pax7. 1 hit.
[Graphical view ]
PRINTSi PR00027. PAIREDBOX.
SMARTi SM00389. HOX. 1 hit.
SM00351. PAX. 1 hit.
[Graphical view ]
SUPFAMi SSF46689. SSF46689. 2 hits.
PROSITEi PS00027. HOMEOBOX_1. 1 hit.
PS50071. HOMEOBOX_2. 1 hit.
PS00034. PAIRED_1. 1 hit.
PS51057. PAIRED_2. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "High-efficiency full-length cDNA cloning."
    Carninci P., Hayashizaki Y.
    Methods Enzymol. 303:19-44(1999) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
    Tissue: Whole bodyImported.
  2. "Normalization and subtraction of cap-trapper-selected cDNAs to prepare full-length cDNA libraries for rapid discovery of new genes."
    Carninci P., Shibata Y., Hayatsu N., Sugahara Y., Shibata K., Itoh M., Konno H., Okazaki Y., Muramatsu M., Hayashizaki Y.
    Genome Res. 10:1617-1630(2000) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
    Tissue: Whole bodyImported.
  3. Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
    Tissue: Whole bodyImported.
  4. Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
    Tissue: Whole bodyImported.
  5. "Functional annotation of a full-length mouse cDNA collection."
    The RIKEN Genome Exploration Research Group Phase II Team and the FANTOM Consortium
    Nature 409:685-690(2001)
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
    Tissue: Whole bodyImported.
  6. "Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs."
    The FANTOM Consortium and the RIKEN Genome Exploration Research Group Phase I and II Team
    Nature 420:563-573(2002)
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
    Tissue: Whole bodyImported.
  7. "The Transcriptional Landscape of the Mammalian Genome."
    The FANTOM Consortium, Riken Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group)
    Science 309:1559-1563(2005)
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
    Tissue: Whole bodyImported.
  8. Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
    Tissue: Whole bodyImported.

Entry informationi

Entry nameiQ9CZK7_MOUSE
AccessioniPrimary (citable) accession number: Q9CZK7
Entry historyi
Integrated into UniProtKB/TrEMBL: June 1, 2001
Last sequence update: March 1, 2003
Last modified: November 26, 2014
This is version 111 of the entry and version 2 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)