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Q9CYZ2 (TPD54_MOUSE) Reviewed, UniProtKB/Swiss-Prot

Last modified April 16, 2014. Version 82. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Tumor protein D54
Alternative name(s):
Tumor protein D52-like 2
Gene names
Name:Tpd52l2
OrganismMus musculus (Mouse) [Reference proteome]
Taxonomic identifier10090 [NCBI]
Taxonomic lineageEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus

Protein attributes

Sequence length220 AA.
Sequence statusComplete.
Protein existenceEvidence at protein level

General annotation (Comments)

Subunit structure

Forms a homodimer or heterodimer with other members of the family. Interacts with MAL2 By similarity.

Sequence similarities

Belongs to the TPD52 family.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 220220Tumor protein D54
PRO_0000185745

Regions

Coiled coil40 – 8243 Potential

Amino acid modifications

Modified residue11N-acetylmethionine By similarity
Modified residue31Phosphoserine By similarity
Modified residue121Phosphoserine By similarity
Modified residue191Phosphoserine By similarity
Modified residue961Phosphoserine By similarity
Modified residue1491Phosphoserine By similarity
Modified residue1801Phosphoserine Ref.4 Ref.5
Modified residue2061Phosphoserine Ref.3 Ref.5

Sequences

Sequence LengthMass (Da)Tools
Q9CYZ2 [UniParc].

Last modified June 1, 2001. Version 1.
Checksum: 276776288500D9C8

FASTA22024,043
        10         20         30         40         50         60 
MDSASQDINL NSPNKGVLSD FMTDVPVDPG VVHRTPVVEG LTEGEEEELR AELAKVEEEI 

        70         80         90        100        110        120 
VTLRQVLAAK ERHCGELKRR LGLSTLGELK QNLSRSWHDV QVSTAYVKTS EKLGEWNEKV 

       130        140        150        160        170        180 
TQSDLYKKTQ ETLSQAGQKT SAALSTMGSA ISRKLGDMSS YSIRHSISMP VMRNSATFKS 

       190        200        210        220 
FEDRVGTIKS KVVGGRENGS DNLPPSPGSG DQTLPDHAPF 

« Hide

References

[1]"The transcriptional landscape of the mammalian genome."
Carninci P., Kasukawa T., Katayama S., Gough J., Frith M.C., Maeda N., Oyama R., Ravasi T., Lenhard B., Wells C., Kodzius R., Shimokawa K., Bajic V.B., Brenner S.E., Batalov S., Forrest A.R., Zavolan M., Davis M.J. expand/collapse author list , Wilming L.G., Aidinis V., Allen J.E., Ambesi-Impiombato A., Apweiler R., Aturaliya R.N., Bailey T.L., Bansal M., Baxter L., Beisel K.W., Bersano T., Bono H., Chalk A.M., Chiu K.P., Choudhary V., Christoffels A., Clutterbuck D.R., Crowe M.L., Dalla E., Dalrymple B.P., de Bono B., Della Gatta G., di Bernardo D., Down T., Engstrom P., Fagiolini M., Faulkner G., Fletcher C.F., Fukushima T., Furuno M., Futaki S., Gariboldi M., Georgii-Hemming P., Gingeras T.R., Gojobori T., Green R.E., Gustincich S., Harbers M., Hayashi Y., Hensch T.K., Hirokawa N., Hill D., Huminiecki L., Iacono M., Ikeo K., Iwama A., Ishikawa T., Jakt M., Kanapin A., Katoh M., Kawasawa Y., Kelso J., Kitamura H., Kitano H., Kollias G., Krishnan S.P., Kruger A., Kummerfeld S.K., Kurochkin I.V., Lareau L.F., Lazarevic D., Lipovich L., Liu J., Liuni S., McWilliam S., Madan Babu M., Madera M., Marchionni L., Matsuda H., Matsuzawa S., Miki H., Mignone F., Miyake S., Morris K., Mottagui-Tabar S., Mulder N., Nakano N., Nakauchi H., Ng P., Nilsson R., Nishiguchi S., Nishikawa S., Nori F., Ohara O., Okazaki Y., Orlando V., Pang K.C., Pavan W.J., Pavesi G., Pesole G., Petrovsky N., Piazza S., Reed J., Reid J.F., Ring B.Z., Ringwald M., Rost B., Ruan Y., Salzberg S.L., Sandelin A., Schneider C., Schoenbach C., Sekiguchi K., Semple C.A., Seno S., Sessa L., Sheng Y., Shibata Y., Shimada H., Shimada K., Silva D., Sinclair B., Sperling S., Stupka E., Sugiura K., Sultana R., Takenaka Y., Taki K., Tammoja K., Tan S.L., Tang S., Taylor M.S., Tegner J., Teichmann S.A., Ueda H.R., van Nimwegen E., Verardo R., Wei C.L., Yagi K., Yamanishi H., Zabarovsky E., Zhu S., Zimmer A., Hide W., Bult C., Grimmond S.M., Teasdale R.D., Liu E.T., Brusic V., Quackenbush J., Wahlestedt C., Mattick J.S., Hume D.A., Kai C., Sasaki D., Tomaru Y., Fukuda S., Kanamori-Katayama M., Suzuki M., Aoki J., Arakawa T., Iida J., Imamura K., Itoh M., Kato T., Kawaji H., Kawagashira N., Kawashima T., Kojima M., Kondo S., Konno H., Nakano K., Ninomiya N., Nishio T., Okada M., Plessy C., Shibata K., Shiraki T., Suzuki S., Tagami M., Waki K., Watahiki A., Okamura-Oho Y., Suzuki H., Kawai J., Hayashizaki Y.
Science 309:1559-1563(2005) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
Strain: C57BL/6J.
[2]"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
Strain: FVB/N.
Tissue: Mammary tumor.
[3]"Phosphoproteomic analysis of the developing mouse brain."
Ballif B.A., Villen J., Beausoleil S.A., Schwartz D., Gygi S.P.
Mol. Cell. Proteomics 3:1093-1101(2004) [PubMed] [Europe PMC] [Abstract]
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-206, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
Tissue: Embryonic brain.
[4]"Specific phosphopeptide enrichment with immobilized titanium ion affinity chromatography adsorbent for phosphoproteome analysis."
Zhou H., Ye M., Dong J., Han G., Jiang X., Wu R., Zou H.
J. Proteome Res. 7:3957-3967(2008) [PubMed] [Europe PMC] [Abstract]
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-180, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
Tissue: Liver.
[5]"Large scale localization of protein phosphorylation by use of electron capture dissociation mass spectrometry."
Sweet S.M., Bailey C.M., Cunningham D.L., Heath J.K., Cooper H.J.
Mol. Cell. Proteomics 8:904-912(2009) [PubMed] [Europe PMC] [Abstract]
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-180 AND SER-206, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
Tissue: Embryonic fibroblast.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AK013188 mRNA. Translation: BAB28701.1.
AK159925 mRNA. Translation: BAE35487.1.
BC006886 mRNA. Translation: AAH06886.1.
RefSeqNP_079758.2. NM_025482.2.
UniGeneMm.136648.

3D structure databases

ProteinModelPortalQ9CYZ2.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

BioGrid211377. 1 interaction.
IntActQ9CYZ2. 2 interactions.
MINTMINT-4126050.

PTM databases

PhosphoSiteQ9CYZ2.

Proteomic databases

PaxDbQ9CYZ2.
PRIDEQ9CYZ2.

Protocols and materials databases

DNASU66314.
StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblENSMUST00000149163; ENSMUSP00000117690; ENSMUSG00000000827.
GeneID66314.
KEGGmmu:66314.
UCSCuc008oml.1. mouse.

Organism-specific databases

CTD7165.
MGIMGI:1913564. Tpd52l2.

Phylogenomic databases

eggNOGNOG329468.
GeneTreeENSGT00390000015988.
HOGENOMHOG000231968.
HOVERGENHBG058643.
OrthoDBEOG744TBQ.
PhylomeDBQ9CYZ2.
TreeFamTF317562.

Gene expression databases

ArrayExpressQ9CYZ2.
BgeeQ9CYZ2.
CleanExMM_TPD52L2.
GenevestigatorQ9CYZ2.

Family and domain databases

InterProIPR007327. TPD52.
[Graphical view]
PANTHERPTHR19307. PTHR19307. 1 hit.
PfamPF04201. TPD52. 1 hit.
[Graphical view]
ProtoNetSearch...

Other

ChiTaRSTPD52L2. mouse.
NextBio321291.
PROQ9CYZ2.
SOURCESearch...

Entry information

Entry nameTPD54_MOUSE
AccessionPrimary (citable) accession number: Q9CYZ2
Secondary accession number(s): Q3TVY1
Entry history
Integrated into UniProtKB/Swiss-Prot: April 12, 2005
Last sequence update: June 1, 2001
Last modified: April 16, 2014
This is version 82 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

MGD cross-references

Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot