Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Basket 0
(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Q9CYZ2

- TPD54_MOUSE

UniProt

Q9CYZ2 - TPD54_MOUSE

Protein

Tumor protein D54

Gene

Tpd52l2

Organism
Mus musculus (Mouse)
Status
Reviewed - Annotation score: 2 out of 5- Experimental evidence at protein leveli
    • BLAST
    • Align
    • Format
    • Add to basket
    • History
      Entry version 86 (01 Oct 2014)
      Sequence version 1 (01 Jun 2001)
      Previous versions | rss
    • Help video
    • Feedback
    • Comment

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Tumor protein D54
    Alternative name(s):
    Tumor protein D52-like 2
    Gene namesi
    Name:Tpd52l2
    OrganismiMus musculus (Mouse)
    Taxonomic identifieri10090 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
    ProteomesiUP000000589: Chromosome 2

    Organism-specific databases

    MGIiMGI:1913564. Tpd52l2.

    Subcellular locationi

    GO - Cellular componenti

    1. cytoplasm Source: UniProtKB
    2. perinuclear region of cytoplasm Source: UniProtKB

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 220220Tumor protein D54PRO_0000185745Add
    BLAST

    Amino acid modifications

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Modified residuei1 – 11N-acetylmethionineBy similarity
    Modified residuei3 – 31PhosphoserineBy similarity
    Modified residuei12 – 121PhosphoserineBy similarity
    Modified residuei19 – 191PhosphoserineBy similarity
    Modified residuei96 – 961PhosphoserineBy similarity
    Modified residuei149 – 1491PhosphoserineBy similarity
    Modified residuei180 – 1801Phosphoserine2 Publications
    Modified residuei206 – 2061Phosphoserine2 Publications

    Keywords - PTMi

    Acetylation, Phosphoprotein

    Proteomic databases

    MaxQBiQ9CYZ2.
    PaxDbiQ9CYZ2.
    PRIDEiQ9CYZ2.

    PTM databases

    PhosphoSiteiQ9CYZ2.

    Expressioni

    Gene expression databases

    ArrayExpressiQ9CYZ2.
    BgeeiQ9CYZ2.
    CleanExiMM_TPD52L2.
    GenevestigatoriQ9CYZ2.

    Interactioni

    Subunit structurei

    Forms a homodimer or heterodimer with other members of the family. Interacts with MAL2 By similarity.By similarity

    Protein-protein interaction databases

    BioGridi211377. 1 interaction.
    IntActiQ9CYZ2. 2 interactions.
    MINTiMINT-4126050.

    Structurei

    3D structure databases

    ProteinModelPortaliQ9CYZ2.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Coiled coil

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Coiled coili40 – 8243Sequence AnalysisAdd
    BLAST

    Sequence similaritiesi

    Belongs to the TPD52 family.Curated

    Keywords - Domaini

    Coiled coil

    Phylogenomic databases

    eggNOGiNOG329468.
    GeneTreeiENSGT00390000015988.
    HOGENOMiHOG000231968.
    HOVERGENiHBG058643.
    OrthoDBiEOG744TBQ.
    PhylomeDBiQ9CYZ2.
    TreeFamiTF317562.

    Family and domain databases

    InterProiIPR007327. TPD52.
    [Graphical view]
    PANTHERiPTHR19307. PTHR19307. 1 hit.
    PfamiPF04201. TPD52. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q9CYZ2-1 [UniParc]FASTAAdd to Basket

    « Hide

    MDSASQDINL NSPNKGVLSD FMTDVPVDPG VVHRTPVVEG LTEGEEEELR    50
    AELAKVEEEI VTLRQVLAAK ERHCGELKRR LGLSTLGELK QNLSRSWHDV 100
    QVSTAYVKTS EKLGEWNEKV TQSDLYKKTQ ETLSQAGQKT SAALSTMGSA 150
    ISRKLGDMSS YSIRHSISMP VMRNSATFKS FEDRVGTIKS KVVGGRENGS 200
    DNLPPSPGSG DQTLPDHAPF 220
    Length:220
    Mass (Da):24,043
    Last modified:June 1, 2001 - v1
    Checksum:i276776288500D9C8
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AK013188 mRNA. Translation: BAB28701.1.
    AK159925 mRNA. Translation: BAE35487.1.
    BC006886 mRNA. Translation: AAH06886.1.
    CCDSiCCDS17214.1.
    RefSeqiNP_001278126.1. NM_001291197.1.
    NP_079758.2. NM_025482.3.
    UniGeneiMm.136648.

    Genome annotation databases

    EnsembliENSMUST00000149163; ENSMUSP00000117690; ENSMUSG00000000827.
    GeneIDi66314.
    KEGGimmu:66314.
    UCSCiuc008oml.1. mouse.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AK013188 mRNA. Translation: BAB28701.1 .
    AK159925 mRNA. Translation: BAE35487.1 .
    BC006886 mRNA. Translation: AAH06886.1 .
    CCDSi CCDS17214.1.
    RefSeqi NP_001278126.1. NM_001291197.1.
    NP_079758.2. NM_025482.3.
    UniGenei Mm.136648.

    3D structure databases

    ProteinModelPortali Q9CYZ2.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    BioGridi 211377. 1 interaction.
    IntActi Q9CYZ2. 2 interactions.
    MINTi MINT-4126050.

    PTM databases

    PhosphoSitei Q9CYZ2.

    Proteomic databases

    MaxQBi Q9CYZ2.
    PaxDbi Q9CYZ2.
    PRIDEi Q9CYZ2.

    Protocols and materials databases

    DNASUi 66314.
    Structural Biology Knowledgebase Search...

    Genome annotation databases

    Ensembli ENSMUST00000149163 ; ENSMUSP00000117690 ; ENSMUSG00000000827 .
    GeneIDi 66314.
    KEGGi mmu:66314.
    UCSCi uc008oml.1. mouse.

    Organism-specific databases

    CTDi 7165.
    MGIi MGI:1913564. Tpd52l2.

    Phylogenomic databases

    eggNOGi NOG329468.
    GeneTreei ENSGT00390000015988.
    HOGENOMi HOG000231968.
    HOVERGENi HBG058643.
    OrthoDBi EOG744TBQ.
    PhylomeDBi Q9CYZ2.
    TreeFami TF317562.

    Miscellaneous databases

    ChiTaRSi TPD52L2. mouse.
    NextBioi 321291.
    PROi Q9CYZ2.
    SOURCEi Search...

    Gene expression databases

    ArrayExpressi Q9CYZ2.
    Bgeei Q9CYZ2.
    CleanExi MM_TPD52L2.
    Genevestigatori Q9CYZ2.

    Family and domain databases

    InterProi IPR007327. TPD52.
    [Graphical view ]
    PANTHERi PTHR19307. PTHR19307. 1 hit.
    Pfami PF04201. TPD52. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "The transcriptional landscape of the mammalian genome."
      Carninci P., Kasukawa T., Katayama S., Gough J., Frith M.C., Maeda N., Oyama R., Ravasi T., Lenhard B., Wells C., Kodzius R., Shimokawa K., Bajic V.B., Brenner S.E., Batalov S., Forrest A.R., Zavolan M., Davis M.J.
      , Wilming L.G., Aidinis V., Allen J.E., Ambesi-Impiombato A., Apweiler R., Aturaliya R.N., Bailey T.L., Bansal M., Baxter L., Beisel K.W., Bersano T., Bono H., Chalk A.M., Chiu K.P., Choudhary V., Christoffels A., Clutterbuck D.R., Crowe M.L., Dalla E., Dalrymple B.P., de Bono B., Della Gatta G., di Bernardo D., Down T., Engstrom P., Fagiolini M., Faulkner G., Fletcher C.F., Fukushima T., Furuno M., Futaki S., Gariboldi M., Georgii-Hemming P., Gingeras T.R., Gojobori T., Green R.E., Gustincich S., Harbers M., Hayashi Y., Hensch T.K., Hirokawa N., Hill D., Huminiecki L., Iacono M., Ikeo K., Iwama A., Ishikawa T., Jakt M., Kanapin A., Katoh M., Kawasawa Y., Kelso J., Kitamura H., Kitano H., Kollias G., Krishnan S.P., Kruger A., Kummerfeld S.K., Kurochkin I.V., Lareau L.F., Lazarevic D., Lipovich L., Liu J., Liuni S., McWilliam S., Madan Babu M., Madera M., Marchionni L., Matsuda H., Matsuzawa S., Miki H., Mignone F., Miyake S., Morris K., Mottagui-Tabar S., Mulder N., Nakano N., Nakauchi H., Ng P., Nilsson R., Nishiguchi S., Nishikawa S., Nori F., Ohara O., Okazaki Y., Orlando V., Pang K.C., Pavan W.J., Pavesi G., Pesole G., Petrovsky N., Piazza S., Reed J., Reid J.F., Ring B.Z., Ringwald M., Rost B., Ruan Y., Salzberg S.L., Sandelin A., Schneider C., Schoenbach C., Sekiguchi K., Semple C.A., Seno S., Sessa L., Sheng Y., Shibata Y., Shimada H., Shimada K., Silva D., Sinclair B., Sperling S., Stupka E., Sugiura K., Sultana R., Takenaka Y., Taki K., Tammoja K., Tan S.L., Tang S., Taylor M.S., Tegner J., Teichmann S.A., Ueda H.R., van Nimwegen E., Verardo R., Wei C.L., Yagi K., Yamanishi H., Zabarovsky E., Zhu S., Zimmer A., Hide W., Bult C., Grimmond S.M., Teasdale R.D., Liu E.T., Brusic V., Quackenbush J., Wahlestedt C., Mattick J.S., Hume D.A., Kai C., Sasaki D., Tomaru Y., Fukuda S., Kanamori-Katayama M., Suzuki M., Aoki J., Arakawa T., Iida J., Imamura K., Itoh M., Kato T., Kawaji H., Kawagashira N., Kawashima T., Kojima M., Kondo S., Konno H., Nakano K., Ninomiya N., Nishio T., Okada M., Plessy C., Shibata K., Shiraki T., Suzuki S., Tagami M., Waki K., Watahiki A., Okamura-Oho Y., Suzuki H., Kawai J., Hayashizaki Y.
      Science 309:1559-1563(2005) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
      Strain: C57BL/6J.
    2. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
      Strain: FVB/N.
      Tissue: Mammary tumor.
    3. Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-206, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
      Tissue: Embryonic brain.
    4. "Specific phosphopeptide enrichment with immobilized titanium ion affinity chromatography adsorbent for phosphoproteome analysis."
      Zhou H., Ye M., Dong J., Han G., Jiang X., Wu R., Zou H.
      J. Proteome Res. 7:3957-3967(2008) [PubMed] [Europe PMC] [Abstract]
      Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-180, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
      Tissue: Liver.
    5. "Large scale localization of protein phosphorylation by use of electron capture dissociation mass spectrometry."
      Sweet S.M., Bailey C.M., Cunningham D.L., Heath J.K., Cooper H.J.
      Mol. Cell. Proteomics 8:904-912(2009) [PubMed] [Europe PMC] [Abstract]
      Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-180 AND SER-206, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
      Tissue: Embryonic fibroblast.

    Entry informationi

    Entry nameiTPD54_MOUSE
    AccessioniPrimary (citable) accession number: Q9CYZ2
    Secondary accession number(s): Q3TVY1
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: April 12, 2005
    Last sequence update: June 1, 2001
    Last modified: October 1, 2014
    This is version 86 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programChordata Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. MGD cross-references
      Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3