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Protein

Golgi-associated plant pathogenesis-related protein 1

Gene

Glipr2

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Names & Taxonomyi

Protein namesi
Recommended name:
Golgi-associated plant pathogenesis-related protein 1
Short name:
GAPR-1
Short name:
Golgi-associated PR-1 protein
Alternative name(s):
Glioma pathogenesis-related protein 2
Short name:
GliPR 2
Gene namesi
Name:Glipr2
Synonyms:Gapr1
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 4

Organism-specific databases

MGIiMGI:1917770. Glipr2.

Subcellular locationi

  • Golgi apparatus membrane; Lipid-anchor

  • Note: Binds lipid-enriched microdomains of Golgi membranes not only by ionic interactions but also through the myristate.By similarity

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Golgi apparatus, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Initiator methionineiRemovedBy similarity
Chaini2 – 154153Golgi-associated plant pathogenesis-related protein 1PRO_0000211525Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Lipidationi2 – 21N-myristoyl glycineBy similarity

Keywords - PTMi

Lipoprotein, Myristate

Proteomic databases

EPDiQ9CYL5.
MaxQBiQ9CYL5.
PaxDbiQ9CYL5.
PeptideAtlasiQ9CYL5.
PRIDEiQ9CYL5.

PTM databases

iPTMnetiQ9CYL5.
PhosphoSiteiQ9CYL5.
SwissPalmiQ9CYL5.

Expressioni

Gene expression databases

BgeeiQ9CYL5.
CleanExiMM_GLIPR2.
ExpressionAtlasiQ9CYL5. baseline and differential.
GenevisibleiQ9CYL5. MM.

Interactioni

Subunit structurei

Homodimer. Interacts with CAV1 (By similarity).By similarity

GO - Molecular functioni

Protein-protein interaction databases

BioGridi239009. 1 interaction.
IntActiQ9CYL5. 2 interactions.
MINTiMINT-4095627.
STRINGi10090.ENSMUSP00000030202.

Structurei

3D structure databases

ProteinModelPortaliQ9CYL5.
SMRiQ9CYL5. Positions 4-154.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini14 – 132119SCPAdd
BLAST

Region

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Regioni91 – 988Interaction with CAV1By similarity

Coiled coil

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Coiled coili30 – 5021Sequence analysisAdd
BLAST

Sequence similaritiesi

Belongs to the CRISP family.Curated
Contains 1 SCP domain.Curated

Keywords - Domaini

Coiled coil

Phylogenomic databases

eggNOGiKOG3017. Eukaryota.
COG2340. LUCA.
GeneTreeiENSGT00390000020276.
HOGENOMiHOG000036879.
HOVERGENiHBG051701.
InParanoidiQ9CYL5.
OMAiWYSEIKS.
OrthoDBiEOG790G2G.
PhylomeDBiQ9CYL5.
TreeFamiTF313138.

Family and domain databases

Gene3Di3.40.33.10. 1 hit.
InterProiIPR001283. Allrgn_V5/Tpx1.
IPR018244. Allrgn_V5/Tpx1_CS.
IPR014044. CAP_domain.
[Graphical view]
PANTHERiPTHR10334. PTHR10334. 1 hit.
PfamiPF00188. CAP. 1 hit.
[Graphical view]
PRINTSiPR00837. V5TPXLIKE.
SMARTiSM00198. SCP. 1 hit.
[Graphical view]
SUPFAMiSSF55797. SSF55797. 1 hit.
PROSITEiPS01009. CRISP_1. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q9CYL5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGKSASKQFN NEVLKAHNEY RAQHGVPPLK LCKKLNREAQ QYSEALASTR
60 70 80 90 100
ILKHSPESSR GQCGENLAWA SYDQTGKDVA DRWYSEIKSY NFQQPGFTSG
110 120 130 140 150
TGHFTAMVWK NTKKIGVGKA SASDGSSFVV ARYFPAGNIV NQGFFEENVP

PPKK
Length:154
Mass (Da):17,090
Last modified:January 23, 2007 - v3
Checksum:i0F00D6180D0B5FFD
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sequence conflicti54 – 541H → R in BAC41014 (PubMed:16141072).Curated
Sequence conflicti75 – 751T → A in BAC41014 (PubMed:16141072).Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK017557 mRNA. Translation: BAB30803.1.
AK089960 mRNA. Translation: BAC41014.1.
AK154433 mRNA. Translation: BAE32583.1.
AK167595 mRNA. Translation: BAE39653.1.
BC031750 mRNA. Translation: AAH31750.1.
CCDSiCCDS18117.1.
RefSeqiNP_081726.1. NM_027450.3.
UniGeneiMm.22213.

Genome annotation databases

EnsembliENSMUST00000030202; ENSMUSP00000030202; ENSMUSG00000028480.
GeneIDi384009.
KEGGimmu:384009.
UCSCiuc008srf.1. mouse.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK017557 mRNA. Translation: BAB30803.1.
AK089960 mRNA. Translation: BAC41014.1.
AK154433 mRNA. Translation: BAE32583.1.
AK167595 mRNA. Translation: BAE39653.1.
BC031750 mRNA. Translation: AAH31750.1.
CCDSiCCDS18117.1.
RefSeqiNP_081726.1. NM_027450.3.
UniGeneiMm.22213.

3D structure databases

ProteinModelPortaliQ9CYL5.
SMRiQ9CYL5. Positions 4-154.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi239009. 1 interaction.
IntActiQ9CYL5. 2 interactions.
MINTiMINT-4095627.
STRINGi10090.ENSMUSP00000030202.

PTM databases

iPTMnetiQ9CYL5.
PhosphoSiteiQ9CYL5.
SwissPalmiQ9CYL5.

Proteomic databases

EPDiQ9CYL5.
MaxQBiQ9CYL5.
PaxDbiQ9CYL5.
PeptideAtlasiQ9CYL5.
PRIDEiQ9CYL5.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000030202; ENSMUSP00000030202; ENSMUSG00000028480.
GeneIDi384009.
KEGGimmu:384009.
UCSCiuc008srf.1. mouse.

Organism-specific databases

CTDi152007.
MGIiMGI:1917770. Glipr2.

Phylogenomic databases

eggNOGiKOG3017. Eukaryota.
COG2340. LUCA.
GeneTreeiENSGT00390000020276.
HOGENOMiHOG000036879.
HOVERGENiHBG051701.
InParanoidiQ9CYL5.
OMAiWYSEIKS.
OrthoDBiEOG790G2G.
PhylomeDBiQ9CYL5.
TreeFamiTF313138.

Miscellaneous databases

PROiQ9CYL5.
SOURCEiSearch...

Gene expression databases

BgeeiQ9CYL5.
CleanExiMM_GLIPR2.
ExpressionAtlasiQ9CYL5. baseline and differential.
GenevisibleiQ9CYL5. MM.

Family and domain databases

Gene3Di3.40.33.10. 1 hit.
InterProiIPR001283. Allrgn_V5/Tpx1.
IPR018244. Allrgn_V5/Tpx1_CS.
IPR014044. CAP_domain.
[Graphical view]
PANTHERiPTHR10334. PTHR10334. 1 hit.
PfamiPF00188. CAP. 1 hit.
[Graphical view]
PRINTSiPR00837. V5TPXLIKE.
SMARTiSM00198. SCP. 1 hit.
[Graphical view]
SUPFAMiSSF55797. SSF55797. 1 hit.
PROSITEiPS01009. CRISP_1. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "The transcriptional landscape of the mammalian genome."
    Carninci P., Kasukawa T., Katayama S., Gough J., Frith M.C., Maeda N., Oyama R., Ravasi T., Lenhard B., Wells C., Kodzius R., Shimokawa K., Bajic V.B., Brenner S.E., Batalov S., Forrest A.R., Zavolan M., Davis M.J.
    , Wilming L.G., Aidinis V., Allen J.E., Ambesi-Impiombato A., Apweiler R., Aturaliya R.N., Bailey T.L., Bansal M., Baxter L., Beisel K.W., Bersano T., Bono H., Chalk A.M., Chiu K.P., Choudhary V., Christoffels A., Clutterbuck D.R., Crowe M.L., Dalla E., Dalrymple B.P., de Bono B., Della Gatta G., di Bernardo D., Down T., Engstrom P., Fagiolini M., Faulkner G., Fletcher C.F., Fukushima T., Furuno M., Futaki S., Gariboldi M., Georgii-Hemming P., Gingeras T.R., Gojobori T., Green R.E., Gustincich S., Harbers M., Hayashi Y., Hensch T.K., Hirokawa N., Hill D., Huminiecki L., Iacono M., Ikeo K., Iwama A., Ishikawa T., Jakt M., Kanapin A., Katoh M., Kawasawa Y., Kelso J., Kitamura H., Kitano H., Kollias G., Krishnan S.P., Kruger A., Kummerfeld S.K., Kurochkin I.V., Lareau L.F., Lazarevic D., Lipovich L., Liu J., Liuni S., McWilliam S., Madan Babu M., Madera M., Marchionni L., Matsuda H., Matsuzawa S., Miki H., Mignone F., Miyake S., Morris K., Mottagui-Tabar S., Mulder N., Nakano N., Nakauchi H., Ng P., Nilsson R., Nishiguchi S., Nishikawa S., Nori F., Ohara O., Okazaki Y., Orlando V., Pang K.C., Pavan W.J., Pavesi G., Pesole G., Petrovsky N., Piazza S., Reed J., Reid J.F., Ring B.Z., Ringwald M., Rost B., Ruan Y., Salzberg S.L., Sandelin A., Schneider C., Schoenbach C., Sekiguchi K., Semple C.A., Seno S., Sessa L., Sheng Y., Shibata Y., Shimada H., Shimada K., Silva D., Sinclair B., Sperling S., Stupka E., Sugiura K., Sultana R., Takenaka Y., Taki K., Tammoja K., Tan S.L., Tang S., Taylor M.S., Tegner J., Teichmann S.A., Ueda H.R., van Nimwegen E., Verardo R., Wei C.L., Yagi K., Yamanishi H., Zabarovsky E., Zhu S., Zimmer A., Hide W., Bult C., Grimmond S.M., Teasdale R.D., Liu E.T., Brusic V., Quackenbush J., Wahlestedt C., Mattick J.S., Hume D.A., Kai C., Sasaki D., Tomaru Y., Fukuda S., Kanamori-Katayama M., Suzuki M., Aoki J., Arakawa T., Iida J., Imamura K., Itoh M., Kato T., Kawaji H., Kawagashira N., Kawashima T., Kojima M., Kondo S., Konno H., Nakano K., Ninomiya N., Nishio T., Okada M., Plessy C., Shibata K., Shiraki T., Suzuki S., Tagami M., Waki K., Watahiki A., Okamura-Oho Y., Suzuki H., Kawai J., Hayashizaki Y.
    Science 309:1559-1563(2005) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Strain: C57BL/6J and NOD.
    Tissue: Embryo.
  2. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Tissue: Mammary tumor.
  3. Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
    Tissue: Brown adipose tissue, Heart, Kidney, Liver, Lung, Pancreas and Spleen.

Entry informationi

Entry nameiGAPR1_MOUSE
AccessioniPrimary (citable) accession number: Q9CYL5
Secondary accession number(s): Q3TJ42, Q8BTK4
Entry historyi
Integrated into UniProtKB/Swiss-Prot: March 29, 2004
Last sequence update: January 23, 2007
Last modified: July 6, 2016
This is version 107 of the entry and version 3 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.