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Protein
Submitted name:

E2F transcription factor 1, isoform CRA_b

Gene

E2f1

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionDNA-bindingUniRule annotation
Biological processTranscription, Transcription regulationUniRule annotation

Names & Taxonomyi

Protein namesi
Submitted name:
E2F transcription factor 1, isoform CRA_bImported
Submitted name:
Transcription factor E2F1Imported
Gene namesi
Name:E2f1Imported
ORF Names:mCG_3689Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 2

Organism-specific databases

MGIiMGI:101941 E2f1

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

NucleusUniRule annotation

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 20Sequence analysisAdd BLAST20
ChainiPRO_501509970621 – 385Sequence analysisAdd BLAST365

Expressioni

Gene expression databases

BgeeiENSMUSG00000027490

Interactioni

GO - Molecular functioni

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini77 – 142E2F_TDPInterPro annotationAdd BLAST66

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili153 – 173Sequence analysisAdd BLAST21

Sequence similaritiesi

Belongs to the E2F/DP family.UniRule annotation

Keywords - Domaini

Coiled coilSequence analysis, SignalSequence analysis

Phylogenomic databases

eggNOGiKOG2577 Eukaryota
ENOG410XNYI LUCA
GeneTreeiENSGT00550000074403
HOGENOMiHOG000232045
HOVERGENiHBG002227
KOiK17454

Family and domain databases

CDDicd14660 E2F_DD, 1 hit
Gene3Di1.10.10.10, 1 hit
InterProiView protein in InterPro
IPR015633 E2F
IPR037241 E2F-DP_heterodim
IPR032198 E2F_CC-MB
IPR003316 E2F_WHTH_DNA-bd_dom
IPR036388 WH-like_DNA-bd_sf
IPR036390 WH_DNA-bd_sf
PANTHERiPTHR12081 PTHR12081, 1 hit
PfamiView protein in Pfam
PF16421 E2F_CC-MB, 1 hit
PF02319 E2F_TDP, 1 hit
SMARTiView protein in SMART
SM01372 E2F_TDP, 1 hit
SUPFAMiSSF144074 SSF144074, 1 hit
SSF46785 SSF46785, 1 hit

Sequencei

Sequence statusi: Complete.

Q9CYB4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGKCFTQLQM VGLIFELMSA GLLQNLWLGS AHSCLLEVKR RLDLETDHQY
60 70 80 90 100
LAGSSGPFRG RGRHPGKGVK SPGEKSRYET SLNLTTKRFL ELLSRSADGV
110 120 130 140 150
VDLNWAAEVL KVQKRRIYDI TNVLEGIQLI AKKSKNHIQW LGSHTMVGIG
160 170 180 190 200
KRLEGLTQDL QQLQESEQQL DHLMHICTTQ LQLLSEDSDT QRLAYVTCQD
210 220 230 240 250
LRSIADPAEQ MVIVIKAPPE TQLQAVDSSE TFQISLKSKQ GPIDVFLCPE
260 270 280 290 300
ESADGISPGK TSCQETSSGE DRTADSGPAG PPPSPPSTSP ALDPSQSLLG
310 320 330 340 350
LEQEAVLPRM GHLRVPMEED QLSPLVAADS LLEHVKEDFS GLLPGEFISL
360 370 380
SPPHEALDYH FGLEEGEGIR DLFDCDFGDL TPLDF
Length:385
Mass (Da):42,323
Last modified:June 1, 2001 - v1
Checksum:iEE01605F07E24578
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL772292 Genomic DNA No translation available.
AK017841 mRNA Translation: BAB30968.1
CH466551 Genomic DNA Translation: EDL06087.1
RefSeqiNP_001278034.1, NM_001291105.1
NP_031917.1, NM_007891.5
UniGeneiMm.18036
Mm.441323

Genome annotation databases

EnsembliENSMUST00000000894; ENSMUSP00000000894; ENSMUSG00000027490
GeneIDi13555
KEGGimmu:13555
UCSCiuc008njl.2 mouse

Similar proteinsi

Entry informationi

Entry nameiQ9CYB4_MOUSE
AccessioniPrimary (citable) accession number: Q9CYB4
Entry historyiIntegrated into UniProtKB/TrEMBL: June 1, 2001
Last sequence update: June 1, 2001
Last modified: June 20, 2018
This is version 144 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

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