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Q9CXX0

- HYLS1_MOUSE

UniProt

Q9CXX0 - HYLS1_MOUSE

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Protein

Hydrolethalus syndrome protein 1 homolog

Gene
Hyls1
Organism
Mus musculus (Mouse)
Status
Reviewed - Annotation score: 2 out of 5 - Experimental evidence at transcript leveli

Names & Taxonomyi

Protein namesi
Recommended name:
Hydrolethalus syndrome protein 1 homolog
Gene namesi
Name:Hyls1
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
ProteomesiUP000000589: Chromosome 9

Organism-specific databases

MGIiMGI:1924082. Hyls1.

Subcellular locationi

Cytoplasm By similarity

GO - Cellular componenti

  1. centrosome Source: Ensembl
  2. cytoplasm Source: MGI
  3. nucleus Source: MGI
  4. plasma membrane Source: Ensembl
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 307307Hydrolethalus syndrome protein 1 homologPRO_0000284927Add
BLAST

Proteomic databases

PRIDEiQ9CXX0.

PTM databases

PhosphoSiteiQ9CXX0.

Expressioni

Tissue specificityi

Expressed in hippocampus and dentate gyrus of 3-month adult brain.1 Publication

Developmental stagei

Detected at each embryonic stage, the highest expression level observed at E11.1 Publication

Gene expression databases

BgeeiQ9CXX0.
CleanExiMM_HYLS1.
GenevestigatoriQ9CXX0.

Family & Domainsi

Sequence similaritiesi

Belongs to the HYLS1 family.

Phylogenomic databases

eggNOGiNOG76010.
GeneTreeiENSGT00390000008848.
HOGENOMiHOG000112979.
HOVERGENiHBG107985.
KOiK16472.
OrthoDBiEOG72C51J.
TreeFamiTF336132.

Family and domain databases

InterProiIPR026227. HYLS1.
IPR027918. HYLS1_C_dom.
[Graphical view]
PfamiPF15311. HYLS1_C. 1 hit.
[Graphical view]
PRINTSiPR02098. HYLETHALUSS1.

Sequencei

Sequence statusi: Complete.

Q9CXX0-1 [UniParc]FASTAAdd to Basket

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MAEKRQAYSV PEAMKQLIGP GGQKWANMDP EERMLAAATA FTRICAGQGE    50
GDSRREAQAG QYDPYSKASV TPGKRPALPM HLHFPHTASR VTSSTVSETS 100
QKCRKPVMKR KVLRRKPDGE VLVTDESVIS ECESGTESDL GLWDLRHRFM 150
NLQFQEGTES PVVTSQKFNL PCEYQGISQE DQLICYLQRE EMDPPVYEQD 200
LIVASRPKSF ILPRLDQLSR NRGKIDRVAR YFEYKRDWDS MRFPGEDHRK 250
ELRWSVRGQM LSRTEPPSKP QHVYVPNNYL VPLRWGVRCD LANGVMPKKL 300
PFPLSPS 307
Length:307
Mass (Da):35,141
Last modified:May 1, 2007 - v2
Checksum:i1F7D5A46BA95B813
GO

Sequence cautioni

The sequence BAB29044.1 differs from that shown. Reason: Frameshift at position 289.
The sequence AAH35953.1 differs from that shown. Reason: Erroneous initiation.

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AK013896 mRNA. Translation: BAB29044.1. Frameshift.
AK131639 mRNA. Translation: BAE20733.1.
BC035953 mRNA. Translation: AAH35953.1. Different initiation.
RefSeqiNP_084038.1. NM_029762.1.
UniGeneiMm.482285.

Genome annotation databases

EnsembliENSMUST00000115110; ENSMUSP00000110762; ENSMUSG00000050555.
GeneIDi76832.
KEGGimmu:76832.
UCSCiuc009oti.2. mouse.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AK013896 mRNA. Translation: BAB29044.1 . Frameshift.
AK131639 mRNA. Translation: BAE20733.1 .
BC035953 mRNA. Translation: AAH35953.1 . Different initiation.
RefSeqi NP_084038.1. NM_029762.1.
UniGenei Mm.482285.

3D structure databases

ModBasei Search...
MobiDBi Search...

PTM databases

PhosphoSitei Q9CXX0.

Proteomic databases

PRIDEi Q9CXX0.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENSMUST00000115110 ; ENSMUSP00000110762 ; ENSMUSG00000050555 .
GeneIDi 76832.
KEGGi mmu:76832.
UCSCi uc009oti.2. mouse.

Organism-specific databases

CTDi 219844.
MGIi MGI:1924082. Hyls1.

Phylogenomic databases

eggNOGi NOG76010.
GeneTreei ENSGT00390000008848.
HOGENOMi HOG000112979.
HOVERGENi HBG107985.
KOi K16472.
OrthoDBi EOG72C51J.
TreeFami TF336132.

Miscellaneous databases

NextBioi 345911.
PROi Q9CXX0.
SOURCEi Search...

Gene expression databases

Bgeei Q9CXX0.
CleanExi MM_HYLS1.
Genevestigatori Q9CXX0.

Family and domain databases

InterProi IPR026227. HYLS1.
IPR027918. HYLS1_C_dom.
[Graphical view ]
Pfami PF15311. HYLS1_C. 1 hit.
[Graphical view ]
PRINTSi PR02098. HYLETHALUSS1.
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "The transcriptional landscape of the mammalian genome."
    Carninci P., Kasukawa T., Katayama S., Gough J., Frith M.C., Maeda N., Oyama R., Ravasi T., Lenhard B., Wells C., Kodzius R., Shimokawa K., Bajic V.B., Brenner S.E., Batalov S., Forrest A.R., Zavolan M., Davis M.J.
    , Wilming L.G., Aidinis V., Allen J.E., Ambesi-Impiombato A., Apweiler R., Aturaliya R.N., Bailey T.L., Bansal M., Baxter L., Beisel K.W., Bersano T., Bono H., Chalk A.M., Chiu K.P., Choudhary V., Christoffels A., Clutterbuck D.R., Crowe M.L., Dalla E., Dalrymple B.P., de Bono B., Della Gatta G., di Bernardo D., Down T., Engstrom P., Fagiolini M., Faulkner G., Fletcher C.F., Fukushima T., Furuno M., Futaki S., Gariboldi M., Georgii-Hemming P., Gingeras T.R., Gojobori T., Green R.E., Gustincich S., Harbers M., Hayashi Y., Hensch T.K., Hirokawa N., Hill D., Huminiecki L., Iacono M., Ikeo K., Iwama A., Ishikawa T., Jakt M., Kanapin A., Katoh M., Kawasawa Y., Kelso J., Kitamura H., Kitano H., Kollias G., Krishnan S.P., Kruger A., Kummerfeld S.K., Kurochkin I.V., Lareau L.F., Lazarevic D., Lipovich L., Liu J., Liuni S., McWilliam S., Madan Babu M., Madera M., Marchionni L., Matsuda H., Matsuzawa S., Miki H., Mignone F., Miyake S., Morris K., Mottagui-Tabar S., Mulder N., Nakano N., Nakauchi H., Ng P., Nilsson R., Nishiguchi S., Nishikawa S., Nori F., Ohara O., Okazaki Y., Orlando V., Pang K.C., Pavan W.J., Pavesi G., Pesole G., Petrovsky N., Piazza S., Reed J., Reid J.F., Ring B.Z., Ringwald M., Rost B., Ruan Y., Salzberg S.L., Sandelin A., Schneider C., Schoenbach C., Sekiguchi K., Semple C.A., Seno S., Sessa L., Sheng Y., Shibata Y., Shimada H., Shimada K., Silva D., Sinclair B., Sperling S., Stupka E., Sugiura K., Sultana R., Takenaka Y., Taki K., Tammoja K., Tan S.L., Tang S., Taylor M.S., Tegner J., Teichmann S.A., Ueda H.R., van Nimwegen E., Verardo R., Wei C.L., Yagi K., Yamanishi H., Zabarovsky E., Zhu S., Zimmer A., Hide W., Bult C., Grimmond S.M., Teasdale R.D., Liu E.T., Brusic V., Quackenbush J., Wahlestedt C., Mattick J.S., Hume D.A., Kai C., Sasaki D., Tomaru Y., Fukuda S., Kanamori-Katayama M., Suzuki M., Aoki J., Arakawa T., Iida J., Imamura K., Itoh M., Kato T., Kawaji H., Kawagashira N., Kawashima T., Kojima M., Kondo S., Konno H., Nakano K., Ninomiya N., Nishio T., Okada M., Plessy C., Shibata K., Shiraki T., Suzuki S., Tagami M., Waki K., Watahiki A., Okamura-Oho Y., Suzuki H., Kawai J., Hayashizaki Y.
    Science 309:1559-1563(2005) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Strain: C57BL/6J.
    Tissue: Cerebellum and Head.
  2. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Strain: FVB/N.
    Tissue: Salivary gland.
  3. Cited for: TISSUE SPECIFICITY, DEVELOPMENTAL STAGE.

Entry informationi

Entry nameiHYLS1_MOUSE
AccessioniPrimary (citable) accession number: Q9CXX0
Secondary accession number(s): Q3V2R4, Q8CI83
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 1, 2007
Last sequence update: May 1, 2007
Last modified: February 19, 2014
This is version 69 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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