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Protein

Eukaryotic translation initiation factor 1b

Gene

Eif1b

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

Probably involved in translation.

GO - Molecular functioni

  1. poly(A) RNA binding Source: MGI
  2. translation initiation factor activity Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

Initiation factor

Keywords - Biological processi

Protein biosynthesis

Names & Taxonomyi

Protein namesi
Recommended name:
Eukaryotic translation initiation factor 1b
Short name:
eIF1b
Gene namesi
Name:Eif1b
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
ProteomesiUP000000589: Chromosome 9

Organism-specific databases

MGIiMGI:1916219. Eif1b.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Initiator methioninei1 – 11RemovedBy similarity
Chaini2 – 113112Eukaryotic translation initiation factor 1bPRO_0000130559Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei2 – 21N-acetylserineBy similarity
Modified residuei9 – 91PhosphoserineBy similarity

Keywords - PTMi

Acetylation, Phosphoprotein

Proteomic databases

MaxQBiQ9CXU9.
PaxDbiQ9CXU9.
PRIDEiQ9CXU9.

PTM databases

PhosphoSiteiQ9CXU9.

Expressioni

Gene expression databases

BgeeiQ9CXU9.
CleanExiMM_EIF1B.
GenevestigatoriQ9CXU9.

Interactioni

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000007139.

Structurei

3D structure databases

ProteinModelPortaliQ9CXU9.
SMRiQ9CXU9. Positions 1-113.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the SUI1 family.Curated

Phylogenomic databases

eggNOGiCOG0023.
GeneTreeiENSGT00390000015789.
HOGENOMiHOG000279813.
HOVERGENiHBG000295.
InParanoidiQ9CXU9.
KOiK03113.
OMAiDKIHIRI.
OrthoDBiEOG76QFKK.
PhylomeDBiQ9CXU9.
TreeFamiTF314417.

Family and domain databases

Gene3Di3.30.780.10. 1 hit.
InterProiIPR005874. SUI1_euk.
IPR001950. TIF_SUI1.
[Graphical view]
PfamiPF01253. SUI1. 1 hit.
[Graphical view]
PIRSFiPIRSF004499. SUI1_euk. 1 hit.
SUPFAMiSSF55159. SSF55159. 1 hit.
TIGRFAMsiTIGR01160. SUI1_MOF2. 1 hit.
PROSITEiPS50296. SUI1. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q9CXU9-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MSTIQNLQSF DPFADATKGD DLLPAGTEDY IHIRIQQRNG RKTLTTVQGI
60 70 80 90 100
ADDYDKKKLV KAFKKKFACN GTVIEHPEYG EVIQLQGDQR KNICQFLLEV
110
GIVKEEQLKV HGF
Length:113
Mass (Da):12,824
Last modified:May 10, 2004 - v2
Checksum:i4522A8B692654FE1
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sequence conflicti21 – 211D → G in BAB29089. (PubMed:16141072)Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK005192 mRNA. Translation: BAB23874.1.
AK013965 mRNA. Translation: BAB29089.1.
BC030319 mRNA. Translation: AAH30319.1.
BC033505 mRNA. Translation: AAH33505.1.
CCDSiCCDS23628.1.
RefSeqiNP_081168.1. NM_026892.3.
UniGeneiMm.28753.

Genome annotation databases

EnsembliENSMUST00000007139; ENSMUSP00000007139; ENSMUSG00000006941.
GeneIDi68969.
KEGGimmu:68969.
UCSCiuc009scp.2. mouse.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK005192 mRNA. Translation: BAB23874.1.
AK013965 mRNA. Translation: BAB29089.1.
BC030319 mRNA. Translation: AAH30319.1.
BC033505 mRNA. Translation: AAH33505.1.
CCDSiCCDS23628.1.
RefSeqiNP_081168.1. NM_026892.3.
UniGeneiMm.28753.

3D structure databases

ProteinModelPortaliQ9CXU9.
SMRiQ9CXU9. Positions 1-113.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000007139.

PTM databases

PhosphoSiteiQ9CXU9.

Proteomic databases

MaxQBiQ9CXU9.
PaxDbiQ9CXU9.
PRIDEiQ9CXU9.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000007139; ENSMUSP00000007139; ENSMUSG00000006941.
GeneIDi68969.
KEGGimmu:68969.
UCSCiuc009scp.2. mouse.

Organism-specific databases

CTDi10289.
MGIiMGI:1916219. Eif1b.

Phylogenomic databases

eggNOGiCOG0023.
GeneTreeiENSGT00390000015789.
HOGENOMiHOG000279813.
HOVERGENiHBG000295.
InParanoidiQ9CXU9.
KOiK03113.
OMAiDKIHIRI.
OrthoDBiEOG76QFKK.
PhylomeDBiQ9CXU9.
TreeFamiTF314417.

Miscellaneous databases

ChiTaRSiEif1b. mouse.
NextBioi328311.
PROiQ9CXU9.
SOURCEiSearch...

Gene expression databases

BgeeiQ9CXU9.
CleanExiMM_EIF1B.
GenevestigatoriQ9CXU9.

Family and domain databases

Gene3Di3.30.780.10. 1 hit.
InterProiIPR005874. SUI1_euk.
IPR001950. TIF_SUI1.
[Graphical view]
PfamiPF01253. SUI1. 1 hit.
[Graphical view]
PIRSFiPIRSF004499. SUI1_euk. 1 hit.
SUPFAMiSSF55159. SSF55159. 1 hit.
TIGRFAMsiTIGR01160. SUI1_MOF2. 1 hit.
PROSITEiPS50296. SUI1. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "The transcriptional landscape of the mammalian genome."
    Carninci P., Kasukawa T., Katayama S., Gough J., Frith M.C., Maeda N., Oyama R., Ravasi T., Lenhard B., Wells C., Kodzius R., Shimokawa K., Bajic V.B., Brenner S.E., Batalov S., Forrest A.R., Zavolan M., Davis M.J.
    , Wilming L.G., Aidinis V., Allen J.E., Ambesi-Impiombato A., Apweiler R., Aturaliya R.N., Bailey T.L., Bansal M., Baxter L., Beisel K.W., Bersano T., Bono H., Chalk A.M., Chiu K.P., Choudhary V., Christoffels A., Clutterbuck D.R., Crowe M.L., Dalla E., Dalrymple B.P., de Bono B., Della Gatta G., di Bernardo D., Down T., Engstrom P., Fagiolini M., Faulkner G., Fletcher C.F., Fukushima T., Furuno M., Futaki S., Gariboldi M., Georgii-Hemming P., Gingeras T.R., Gojobori T., Green R.E., Gustincich S., Harbers M., Hayashi Y., Hensch T.K., Hirokawa N., Hill D., Huminiecki L., Iacono M., Ikeo K., Iwama A., Ishikawa T., Jakt M., Kanapin A., Katoh M., Kawasawa Y., Kelso J., Kitamura H., Kitano H., Kollias G., Krishnan S.P., Kruger A., Kummerfeld S.K., Kurochkin I.V., Lareau L.F., Lazarevic D., Lipovich L., Liu J., Liuni S., McWilliam S., Madan Babu M., Madera M., Marchionni L., Matsuda H., Matsuzawa S., Miki H., Mignone F., Miyake S., Morris K., Mottagui-Tabar S., Mulder N., Nakano N., Nakauchi H., Ng P., Nilsson R., Nishiguchi S., Nishikawa S., Nori F., Ohara O., Okazaki Y., Orlando V., Pang K.C., Pavan W.J., Pavesi G., Pesole G., Petrovsky N., Piazza S., Reed J., Reid J.F., Ring B.Z., Ringwald M., Rost B., Ruan Y., Salzberg S.L., Sandelin A., Schneider C., Schoenbach C., Sekiguchi K., Semple C.A., Seno S., Sessa L., Sheng Y., Shibata Y., Shimada H., Shimada K., Silva D., Sinclair B., Sperling S., Stupka E., Sugiura K., Sultana R., Takenaka Y., Taki K., Tammoja K., Tan S.L., Tang S., Taylor M.S., Tegner J., Teichmann S.A., Ueda H.R., van Nimwegen E., Verardo R., Wei C.L., Yagi K., Yamanishi H., Zabarovsky E., Zhu S., Zimmer A., Hide W., Bult C., Grimmond S.M., Teasdale R.D., Liu E.T., Brusic V., Quackenbush J., Wahlestedt C., Mattick J.S., Hume D.A., Kai C., Sasaki D., Tomaru Y., Fukuda S., Kanamori-Katayama M., Suzuki M., Aoki J., Arakawa T., Iida J., Imamura K., Itoh M., Kato T., Kawaji H., Kawagashira N., Kawashima T., Kojima M., Kondo S., Konno H., Nakano K., Ninomiya N., Nishio T., Okada M., Plessy C., Shibata K., Shiraki T., Suzuki S., Tagami M., Waki K., Watahiki A., Okamura-Oho Y., Suzuki H., Kawai J., Hayashizaki Y.
    Science 309:1559-1563(2005) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Strain: C57BL/6J.
    Tissue: Cerebellum and Embryo.
  2. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Strain: FVB/N.
    Tissue: Colon and Mammary tumor.

Entry informationi

Entry nameiEIF1B_MOUSE
AccessioniPrimary (citable) accession number: Q9CXU9
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 10, 2004
Last sequence update: May 10, 2004
Last modified: February 4, 2015
This is version 90 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Translation initiation factors
    List of translation initiation factor entries
  2. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
  3. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.