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Q9CX80 (CYGB_MOUSE) Reviewed, UniProtKB/Swiss-Prot

Last modified July 9, 2014. Version 99. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Cytoglobin
Alternative name(s):
Histoglobin
Short name=HGb
Gene names
Name:Cygb
OrganismMus musculus (Mouse) [Reference proteome]
Taxonomic identifier10090 [NCBI]
Taxonomic lineageEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus

Protein attributes

Sequence length190 AA.
Sequence statusComplete.
Protein existenceEvidence at transcript level

General annotation (Comments)

Function

May have a protective function during conditions of oxidative stress. May be involved in intracellular oxygen storage or transfer.

Subcellular location

Cytoplasm By similarity.

Sequence similarities

Belongs to the globin family.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 190190Cytoglobin
PRO_0000053385

Regions

Region17 – 167151Globin

Sites

Metal binding811Iron (heme distal ligand) By similarity
Metal binding1131Iron (heme proximal ligand) By similarity

Sequences

Sequence LengthMass (Da)Tools
Q9CX80 [UniParc].

Last modified June 1, 2001. Version 1.
Checksum: 6B1A50403F790FF7

FASTA19021,466
        10         20         30         40         50         60 
MEKVPGDMEI ERRERSEELS EAERKAVQAT WARLYANCED VGVAILVRFF VNFPSAKQYF 

        70         80         90        100        110        120 
SQFRHMEDPL EMERSPQLRK HACRVMGALN TVVENLHDPD KVSSVLALVG KAHALKHKVE 

       130        140        150        160        170        180 
PMYFKILSGV ILEVIAEEFA NDFPVETQKA WAKLRGLIYS HVTAAYKEVG WVQQVPNTTT 

       190 
PPATLPSSGP 

« Hide

References

« Hide 'large scale' references
[1]"Cytoglobin: a novel globin type ubiquitously expressed in vertebrate tissues."
Burmester T., Ebner B., Weich B., Hankeln T.
Mol. Biol. Evol. 19:416-421(2002) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [MRNA].
Tissue: Brain.
[2]"The transcriptional landscape of the mammalian genome."
Carninci P., Kasukawa T., Katayama S., Gough J., Frith M.C., Maeda N., Oyama R., Ravasi T., Lenhard B., Wells C., Kodzius R., Shimokawa K., Bajic V.B., Brenner S.E., Batalov S., Forrest A.R., Zavolan M., Davis M.J. expand/collapse author list , Wilming L.G., Aidinis V., Allen J.E., Ambesi-Impiombato A., Apweiler R., Aturaliya R.N., Bailey T.L., Bansal M., Baxter L., Beisel K.W., Bersano T., Bono H., Chalk A.M., Chiu K.P., Choudhary V., Christoffels A., Clutterbuck D.R., Crowe M.L., Dalla E., Dalrymple B.P., de Bono B., Della Gatta G., di Bernardo D., Down T., Engstrom P., Fagiolini M., Faulkner G., Fletcher C.F., Fukushima T., Furuno M., Futaki S., Gariboldi M., Georgii-Hemming P., Gingeras T.R., Gojobori T., Green R.E., Gustincich S., Harbers M., Hayashi Y., Hensch T.K., Hirokawa N., Hill D., Huminiecki L., Iacono M., Ikeo K., Iwama A., Ishikawa T., Jakt M., Kanapin A., Katoh M., Kawasawa Y., Kelso J., Kitamura H., Kitano H., Kollias G., Krishnan S.P., Kruger A., Kummerfeld S.K., Kurochkin I.V., Lareau L.F., Lazarevic D., Lipovich L., Liu J., Liuni S., McWilliam S., Madan Babu M., Madera M., Marchionni L., Matsuda H., Matsuzawa S., Miki H., Mignone F., Miyake S., Morris K., Mottagui-Tabar S., Mulder N., Nakano N., Nakauchi H., Ng P., Nilsson R., Nishiguchi S., Nishikawa S., Nori F., Ohara O., Okazaki Y., Orlando V., Pang K.C., Pavan W.J., Pavesi G., Pesole G., Petrovsky N., Piazza S., Reed J., Reid J.F., Ring B.Z., Ringwald M., Rost B., Ruan Y., Salzberg S.L., Sandelin A., Schneider C., Schoenbach C., Sekiguchi K., Semple C.A., Seno S., Sessa L., Sheng Y., Shibata Y., Shimada H., Shimada K., Silva D., Sinclair B., Sperling S., Stupka E., Sugiura K., Sultana R., Takenaka Y., Taki K., Tammoja K., Tan S.L., Tang S., Taylor M.S., Tegner J., Teichmann S.A., Ueda H.R., van Nimwegen E., Verardo R., Wei C.L., Yagi K., Yamanishi H., Zabarovsky E., Zhu S., Zimmer A., Hide W., Bult C., Grimmond S.M., Teasdale R.D., Liu E.T., Brusic V., Quackenbush J., Wahlestedt C., Mattick J.S., Hume D.A., Kai C., Sasaki D., Tomaru Y., Fukuda S., Kanamori-Katayama M., Suzuki M., Aoki J., Arakawa T., Iida J., Imamura K., Itoh M., Kato T., Kawaji H., Kawagashira N., Kawashima T., Kojima M., Kondo S., Konno H., Nakano K., Ninomiya N., Nishio T., Okada M., Plessy C., Shibata K., Shiraki T., Suzuki S., Tagami M., Waki K., Watahiki A., Okamura-Oho Y., Suzuki H., Kawai J., Hayashizaki Y.
Science 309:1559-1563(2005) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
Strain: C57BL/6J.
Tissue: Embryonic head.
[3]"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
Tissue: Eye.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AJ315163 mRNA. Translation: CAC86187.1.
AK019410 mRNA. Translation: BAB31709.1.
BC055040 mRNA. Translation: AAH55040.1.
CCDSCCDS25673.1.
RefSeqNP_084482.1. NM_030206.4.
UniGeneMm.34598.

3D structure databases

ProteinModelPortalQ9CX80.
SMRQ9CX80. Positions 21-171.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

IntActQ9CX80. 1 interaction.
MINTMINT-4092722.

PTM databases

PhosphoSiteQ9CX80.

Proteomic databases

MaxQBQ9CX80.
PaxDbQ9CX80.
PRIDEQ9CX80.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblENSMUST00000021166; ENSMUSP00000021166; ENSMUSG00000020810.
GeneID114886.
KEGGmmu:114886.
UCSCuc007mlv.1. mouse.

Organism-specific databases

CTD114757.
MGIMGI:2149481. Cygb.

Phylogenomic databases

eggNOGNOG278586.
GeneTreeENSGT00730000110844.
HOGENOMHOG000112127.
HOVERGENHBG100250.
InParanoidQ9CX80.
OMATHVTAAY.
OrthoDBEOG7KSX9V.
PhylomeDBQ9CX80.
TreeFamTF332967.

Gene expression databases

ArrayExpressQ9CX80.
BgeeQ9CX80.
CleanExMM_CYGB.
GenevestigatorQ9CX80.

Family and domain databases

Gene3D1.10.490.10. 1 hit.
InterProIPR000971. Globin.
IPR009050. Globin-like.
IPR012292. Globin_dom.
IPR013314. Globin_lamprey/hagfish.
[Graphical view]
PfamPF00042. Globin. 1 hit.
[Graphical view]
PRINTSPR01906. FISHGLOBIN.
SUPFAMSSF46458. SSF46458. 1 hit.
PROSITEPS01033. GLOBIN. 1 hit.
[Graphical view]
ProtoNetSearch...

Other

NextBio368903.
PROQ9CX80.
SOURCESearch...

Entry information

Entry nameCYGB_MOUSE
AccessionPrimary (citable) accession number: Q9CX80
Entry history
Integrated into UniProtKB/Swiss-Prot: May 27, 2002
Last sequence update: June 1, 2001
Last modified: July 9, 2014
This is version 99 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

MGD cross-references

Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot