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Protein

Protein YIF1B

Gene

Yif1b

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at protein leveli

Functioni

GO - Biological processi

Complete GO annotation...

Names & Taxonomyi

Protein namesi
Recommended name:
Protein YIF1B
Alternative name(s):
YIP1-interacting factor homolog B
Gene namesi
Name:Yif1b
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 7

Organism-specific databases

MGIiMGI:1924504. Yif1b.

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Topological domaini1 – 153CytoplasmicSequence analysisAdd BLAST153
Transmembranei154 – 174HelicalSequence analysisAdd BLAST21
Topological domaini175 – 189ExtracellularSequence analysisAdd BLAST15
Transmembranei190 – 210HelicalSequence analysisAdd BLAST21
Topological domaini211 – 216CytoplasmicSequence analysis6
Transmembranei217 – 237HelicalSequence analysisAdd BLAST21
Topological domaini238ExtracellularSequence analysis1
Transmembranei239 – 259HelicalSequence analysisAdd BLAST21
Topological domaini260 – 289CytoplasmicSequence analysisAdd BLAST30
Transmembranei290 – 310HelicalSequence analysisAdd BLAST21
Topological domaini311ExtracellularSequence analysis1

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00003072591 – 311Protein YIF1BAdd BLAST311

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei1N-acetylmethionineCombined sources1
Modified residuei12PhosphothreonineCombined sources1
Modified residuei64PhosphoserineBy similarity1

Keywords - PTMi

Acetylation, Phosphoprotein

Proteomic databases

PaxDbiQ9CX30.
PeptideAtlasiQ9CX30.
PRIDEiQ9CX30.

PTM databases

iPTMnetiQ9CX30.
PhosphoSitePlusiQ9CX30.

Expressioni

Gene expression databases

BgeeiENSMUSG00000030588.
CleanExiMM_YIF1B.
ExpressionAtlasiQ9CX30. baseline and differential.
GenevisibleiQ9CX30. MM.

Interactioni

Protein-protein interaction databases

IntActiQ9CX30. 2 interactors.
MINTiMINT-1740441.
STRINGi10090.ENSMUSP00000032809.

Structurei

3D structure databases

ProteinModelPortaliQ9CX30.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the YIF1 family.Curated

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiKOG3094. Eukaryota.
COG5197. LUCA.
GeneTreeiENSGT00390000009423.
HOGENOMiHOG000234333.
HOVERGENiHBG053252.
InParanoidiQ9CX30.
KOiK20362.
OrthoDBiEOG091G0H35.
PhylomeDBiQ9CX30.
TreeFamiTF314528.

Family and domain databases

InterProiIPR005578. Yif1_fam.
[Graphical view]
PANTHERiPTHR14083. PTHR14083. 1 hit.

Sequences (2)i

Sequence statusi: Complete.

This entry describes 2 isoformsi produced by alternative splicing. AlignAdd to basket

Isoform 1 (identifier: Q9CX30-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide

        10         20         30         40         50
MHATGLAAPA GTPRLRKWPS KRRVPVSQPG MADPHQFFDD TSSAPSRGYG
60 70 80 90 100
GQPSPGGLGY PPSSSDAAFL AAPMSNMAMV YGSSLAAQGK ELVDKNIDRF
110 120 130 140 150
IPVSKLKYYF AVDTVYVGKK LGLLVFPYLH QDWEVQYQQD TPVAPRFDIN
160 170 180 190 200
APDLYIPAMA FITYILVAGL ALGTQDRFSP DLLGLQASSA LAWLTLEVVA
210 220 230 240 250
ILLSLYLVTV NTDLTTIDLV AFLGYKYVGM IGGVLTGLLF GKIGYYLVLA
260 270 280 290 300
WCCVSIFVFM IRTLRLKILA QAAAEGVPVR GARNQLRMYL TMAVAAAQPV
310
LMYWLTFHLV R
Length:311
Mass (Da):33,983
Last modified:October 23, 2007 - v2
Checksum:iBFC353B2D2C37074
GO
Isoform 2 (identifier: Q9CX30-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     16-18: Missing.

Show »
Length:308
Mass (Da):33,512
Checksum:i10A27B500D1525D6
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti160A → G in BAB32103 (PubMed:16141072).Curated1
Sequence conflicti197E → K in BAB32103 (PubMed:16141072).Curated1
Sequence conflicti277V → E in BAE22568 (PubMed:16141072).Curated1

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Alternative sequenceiVSP_02865616 – 18Missing in isoform 2. 2 Publications3

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK020444 mRNA. Translation: BAB32103.1.
AK135529 mRNA. Translation: BAE22568.1.
BC109331 mRNA. Translation: AAI09332.1.
CCDSiCCDS21069.1. [Q9CX30-1]
CCDS52171.1. [Q9CX30-2]
RefSeqiNP_001103671.1. NM_001110201.1. [Q9CX30-2]
NP_084163.2. NM_029887.3. [Q9CX30-1]
UniGeneiMm.36699.

Genome annotation databases

EnsembliENSMUST00000032809; ENSMUSP00000032809; ENSMUSG00000030588. [Q9CX30-1]
ENSMUST00000108238; ENSMUSP00000103873; ENSMUSG00000030588. [Q9CX30-2]
GeneIDi77254.
KEGGimmu:77254.
UCSCiuc009gbh.2. mouse. [Q9CX30-2]
uc009gbi.2. mouse. [Q9CX30-1]

Keywords - Coding sequence diversityi

Alternative splicing

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK020444 mRNA. Translation: BAB32103.1.
AK135529 mRNA. Translation: BAE22568.1.
BC109331 mRNA. Translation: AAI09332.1.
CCDSiCCDS21069.1. [Q9CX30-1]
CCDS52171.1. [Q9CX30-2]
RefSeqiNP_001103671.1. NM_001110201.1. [Q9CX30-2]
NP_084163.2. NM_029887.3. [Q9CX30-1]
UniGeneiMm.36699.

3D structure databases

ProteinModelPortaliQ9CX30.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

IntActiQ9CX30. 2 interactors.
MINTiMINT-1740441.
STRINGi10090.ENSMUSP00000032809.

PTM databases

iPTMnetiQ9CX30.
PhosphoSitePlusiQ9CX30.

Proteomic databases

PaxDbiQ9CX30.
PeptideAtlasiQ9CX30.
PRIDEiQ9CX30.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000032809; ENSMUSP00000032809; ENSMUSG00000030588. [Q9CX30-1]
ENSMUST00000108238; ENSMUSP00000103873; ENSMUSG00000030588. [Q9CX30-2]
GeneIDi77254.
KEGGimmu:77254.
UCSCiuc009gbh.2. mouse. [Q9CX30-2]
uc009gbi.2. mouse. [Q9CX30-1]

Organism-specific databases

CTDi90522.
MGIiMGI:1924504. Yif1b.

Phylogenomic databases

eggNOGiKOG3094. Eukaryota.
COG5197. LUCA.
GeneTreeiENSGT00390000009423.
HOGENOMiHOG000234333.
HOVERGENiHBG053252.
InParanoidiQ9CX30.
KOiK20362.
OrthoDBiEOG091G0H35.
PhylomeDBiQ9CX30.
TreeFamiTF314528.

Miscellaneous databases

ChiTaRSiYif1b. mouse.
PROiQ9CX30.
SOURCEiSearch...

Gene expression databases

BgeeiENSMUSG00000030588.
CleanExiMM_YIF1B.
ExpressionAtlasiQ9CX30. baseline and differential.
GenevisibleiQ9CX30. MM.

Family and domain databases

InterProiIPR005578. Yif1_fam.
[Graphical view]
PANTHERiPTHR14083. PTHR14083. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiYIF1B_MOUSE
AccessioniPrimary (citable) accession number: Q9CX30
Secondary accession number(s): Q32M25, Q3UXJ5
Entry historyi
Integrated into UniProtKB/Swiss-Prot: October 23, 2007
Last sequence update: October 23, 2007
Last modified: November 2, 2016
This is version 96 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.