Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Protein YIF1B

Gene

Yif1b

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Names & Taxonomyi

Protein namesi
Recommended name:
Protein YIF1B
Alternative name(s):
YIP1-interacting factor homolog B
Gene namesi
Name:Yif1b
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 7

Organism-specific databases

MGIiMGI:1924504. Yif1b.

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Topological domaini1 – 153153CytoplasmicSequence analysisAdd
BLAST
Transmembranei154 – 17421HelicalSequence analysisAdd
BLAST
Topological domaini175 – 18915ExtracellularSequence analysisAdd
BLAST
Transmembranei190 – 21021HelicalSequence analysisAdd
BLAST
Topological domaini211 – 2166CytoplasmicSequence analysis
Transmembranei217 – 23721HelicalSequence analysisAdd
BLAST
Topological domaini238 – 2381ExtracellularSequence analysis
Transmembranei239 – 25921HelicalSequence analysisAdd
BLAST
Topological domaini260 – 28930CytoplasmicSequence analysisAdd
BLAST
Transmembranei290 – 31021HelicalSequence analysisAdd
BLAST
Topological domaini311 – 3111ExtracellularSequence analysis

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 311311Protein YIF1BPRO_0000307259Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei1 – 11N-acetylmethionineCombined sources
Modified residuei12 – 121PhosphothreonineCombined sources
Modified residuei64 – 641PhosphoserineBy similarity

Keywords - PTMi

Acetylation, Phosphoprotein

Proteomic databases

EPDiQ9CX30.
MaxQBiQ9CX30.
PaxDbiQ9CX30.
PeptideAtlasiQ9CX30.
PRIDEiQ9CX30.

PTM databases

iPTMnetiQ9CX30.
PhosphoSiteiQ9CX30.

Expressioni

Gene expression databases

BgeeiQ9CX30.
CleanExiMM_YIF1B.
ExpressionAtlasiQ9CX30. baseline and differential.
GenevisibleiQ9CX30. MM.

Interactioni

Protein-protein interaction databases

IntActiQ9CX30. 2 interactions.
MINTiMINT-1740441.
STRINGi10090.ENSMUSP00000032809.

Structurei

3D structure databases

ProteinModelPortaliQ9CX30.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the YIF1 family.Curated

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiKOG3094. Eukaryota.
COG5197. LUCA.
GeneTreeiENSGT00390000009423.
HOGENOMiHOG000234333.
HOVERGENiHBG053252.
InParanoidiQ9CX30.
OMAiVLMWWLS.
OrthoDBiEOG7SXW3T.
PhylomeDBiQ9CX30.
TreeFamiTF314528.

Family and domain databases

InterProiIPR005578. Yif1_fam.
[Graphical view]
PANTHERiPTHR14083. PTHR14083. 1 hit.

Sequences (2)i

Sequence statusi: Complete.

This entry describes 2 isoformsi produced by alternative splicing. AlignAdd to basket

Isoform 1 (identifier: Q9CX30-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide

        10         20         30         40         50
MHATGLAAPA GTPRLRKWPS KRRVPVSQPG MADPHQFFDD TSSAPSRGYG
60 70 80 90 100
GQPSPGGLGY PPSSSDAAFL AAPMSNMAMV YGSSLAAQGK ELVDKNIDRF
110 120 130 140 150
IPVSKLKYYF AVDTVYVGKK LGLLVFPYLH QDWEVQYQQD TPVAPRFDIN
160 170 180 190 200
APDLYIPAMA FITYILVAGL ALGTQDRFSP DLLGLQASSA LAWLTLEVVA
210 220 230 240 250
ILLSLYLVTV NTDLTTIDLV AFLGYKYVGM IGGVLTGLLF GKIGYYLVLA
260 270 280 290 300
WCCVSIFVFM IRTLRLKILA QAAAEGVPVR GARNQLRMYL TMAVAAAQPV
310
LMYWLTFHLV R
Length:311
Mass (Da):33,983
Last modified:October 23, 2007 - v2
Checksum:iBFC353B2D2C37074
GO
Isoform 2 (identifier: Q9CX30-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     16-18: Missing.

Show »
Length:308
Mass (Da):33,512
Checksum:i10A27B500D1525D6
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sequence conflicti160 – 1601A → G in BAB32103 (PubMed:16141072).Curated
Sequence conflicti197 – 1971E → K in BAB32103 (PubMed:16141072).Curated
Sequence conflicti277 – 2771V → E in BAE22568 (PubMed:16141072).Curated

Alternative sequence

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Alternative sequencei16 – 183Missing in isoform 2. 2 PublicationsVSP_028656

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK020444 mRNA. Translation: BAB32103.1.
AK135529 mRNA. Translation: BAE22568.1.
BC109331 mRNA. Translation: AAI09332.1.
CCDSiCCDS21069.1. [Q9CX30-1]
CCDS52171.1. [Q9CX30-2]
RefSeqiNP_001103671.1. NM_001110201.1. [Q9CX30-2]
NP_084163.2. NM_029887.3. [Q9CX30-1]
UniGeneiMm.36699.

Genome annotation databases

EnsembliENSMUST00000032809; ENSMUSP00000032809; ENSMUSG00000030588. [Q9CX30-1]
ENSMUST00000108238; ENSMUSP00000103873; ENSMUSG00000030588. [Q9CX30-2]
GeneIDi77254.
KEGGimmu:77254.
UCSCiuc009gbh.2. mouse. [Q9CX30-2]
uc009gbi.2. mouse. [Q9CX30-1]

Keywords - Coding sequence diversityi

Alternative splicing

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK020444 mRNA. Translation: BAB32103.1.
AK135529 mRNA. Translation: BAE22568.1.
BC109331 mRNA. Translation: AAI09332.1.
CCDSiCCDS21069.1. [Q9CX30-1]
CCDS52171.1. [Q9CX30-2]
RefSeqiNP_001103671.1. NM_001110201.1. [Q9CX30-2]
NP_084163.2. NM_029887.3. [Q9CX30-1]
UniGeneiMm.36699.

3D structure databases

ProteinModelPortaliQ9CX30.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

IntActiQ9CX30. 2 interactions.
MINTiMINT-1740441.
STRINGi10090.ENSMUSP00000032809.

PTM databases

iPTMnetiQ9CX30.
PhosphoSiteiQ9CX30.

Proteomic databases

EPDiQ9CX30.
MaxQBiQ9CX30.
PaxDbiQ9CX30.
PeptideAtlasiQ9CX30.
PRIDEiQ9CX30.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000032809; ENSMUSP00000032809; ENSMUSG00000030588. [Q9CX30-1]
ENSMUST00000108238; ENSMUSP00000103873; ENSMUSG00000030588. [Q9CX30-2]
GeneIDi77254.
KEGGimmu:77254.
UCSCiuc009gbh.2. mouse. [Q9CX30-2]
uc009gbi.2. mouse. [Q9CX30-1]

Organism-specific databases

CTDi90522.
MGIiMGI:1924504. Yif1b.

Phylogenomic databases

eggNOGiKOG3094. Eukaryota.
COG5197. LUCA.
GeneTreeiENSGT00390000009423.
HOGENOMiHOG000234333.
HOVERGENiHBG053252.
InParanoidiQ9CX30.
OMAiVLMWWLS.
OrthoDBiEOG7SXW3T.
PhylomeDBiQ9CX30.
TreeFamiTF314528.

Miscellaneous databases

ChiTaRSiYif1b. mouse.
PROiQ9CX30.
SOURCEiSearch...

Gene expression databases

BgeeiQ9CX30.
CleanExiMM_YIF1B.
ExpressionAtlasiQ9CX30. baseline and differential.
GenevisibleiQ9CX30. MM.

Family and domain databases

InterProiIPR005578. Yif1_fam.
[Graphical view]
PANTHERiPTHR14083. PTHR14083. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. "The transcriptional landscape of the mammalian genome."
    Carninci P., Kasukawa T., Katayama S., Gough J., Frith M.C., Maeda N., Oyama R., Ravasi T., Lenhard B., Wells C., Kodzius R., Shimokawa K., Bajic V.B., Brenner S.E., Batalov S., Forrest A.R., Zavolan M., Davis M.J.
    , Wilming L.G., Aidinis V., Allen J.E., Ambesi-Impiombato A., Apweiler R., Aturaliya R.N., Bailey T.L., Bansal M., Baxter L., Beisel K.W., Bersano T., Bono H., Chalk A.M., Chiu K.P., Choudhary V., Christoffels A., Clutterbuck D.R., Crowe M.L., Dalla E., Dalrymple B.P., de Bono B., Della Gatta G., di Bernardo D., Down T., Engstrom P., Fagiolini M., Faulkner G., Fletcher C.F., Fukushima T., Furuno M., Futaki S., Gariboldi M., Georgii-Hemming P., Gingeras T.R., Gojobori T., Green R.E., Gustincich S., Harbers M., Hayashi Y., Hensch T.K., Hirokawa N., Hill D., Huminiecki L., Iacono M., Ikeo K., Iwama A., Ishikawa T., Jakt M., Kanapin A., Katoh M., Kawasawa Y., Kelso J., Kitamura H., Kitano H., Kollias G., Krishnan S.P., Kruger A., Kummerfeld S.K., Kurochkin I.V., Lareau L.F., Lazarevic D., Lipovich L., Liu J., Liuni S., McWilliam S., Madan Babu M., Madera M., Marchionni L., Matsuda H., Matsuzawa S., Miki H., Mignone F., Miyake S., Morris K., Mottagui-Tabar S., Mulder N., Nakano N., Nakauchi H., Ng P., Nilsson R., Nishiguchi S., Nishikawa S., Nori F., Ohara O., Okazaki Y., Orlando V., Pang K.C., Pavan W.J., Pavesi G., Pesole G., Petrovsky N., Piazza S., Reed J., Reid J.F., Ring B.Z., Ringwald M., Rost B., Ruan Y., Salzberg S.L., Sandelin A., Schneider C., Schoenbach C., Sekiguchi K., Semple C.A., Seno S., Sessa L., Sheng Y., Shibata Y., Shimada H., Shimada K., Silva D., Sinclair B., Sperling S., Stupka E., Sugiura K., Sultana R., Takenaka Y., Taki K., Tammoja K., Tan S.L., Tang S., Taylor M.S., Tegner J., Teichmann S.A., Ueda H.R., van Nimwegen E., Verardo R., Wei C.L., Yagi K., Yamanishi H., Zabarovsky E., Zhu S., Zimmer A., Hide W., Bult C., Grimmond S.M., Teasdale R.D., Liu E.T., Brusic V., Quackenbush J., Wahlestedt C., Mattick J.S., Hume D.A., Kai C., Sasaki D., Tomaru Y., Fukuda S., Kanamori-Katayama M., Suzuki M., Aoki J., Arakawa T., Iida J., Imamura K., Itoh M., Kato T., Kawaji H., Kawagashira N., Kawashima T., Kojima M., Kondo S., Konno H., Nakano K., Ninomiya N., Nishio T., Okada M., Plessy C., Shibata K., Shiraki T., Suzuki S., Tagami M., Waki K., Watahiki A., Okamura-Oho Y., Suzuki H., Kawai J., Hayashizaki Y.
    Science 309:1559-1563(2005) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 1 AND 2).
    Strain: C57BL/6J.
    Tissue: Embryo and Muellerian duct.
  2. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2).
  3. Cited for: ACETYLATION [LARGE SCALE ANALYSIS] AT MET-1, PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT THR-12, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
    Tissue: Liver.
  4. Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
    Tissue: Brain, Brown adipose tissue, Heart, Kidney, Liver, Lung, Pancreas, Spleen and Testis.

Entry informationi

Entry nameiYIF1B_MOUSE
AccessioniPrimary (citable) accession number: Q9CX30
Secondary accession number(s): Q32M25, Q3UXJ5
Entry historyi
Integrated into UniProtKB/Swiss-Prot: October 23, 2007
Last sequence update: October 23, 2007
Last modified: July 6, 2016
This is version 93 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.