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Q9CW15

- Q9CW15_MOUSE

UniProt

Q9CW15 - Q9CW15_MOUSE

Protein
Submitted name:

Putative uncharacterized protein

Gene

Cul4a

Organism
Mus musculus (Mouse)
Status
Unreviewed - Annotation score: 4 out of 5- Experimental evidence at transcript leveli
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    • History
      Entry version 81 (01 Oct 2014)
      Sequence version 1 (01 Jun 2001)
      Previous versions | rss
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    Functioni

    GO - Molecular functioni

    1. protein binding Source: MGI

    GO - Biological processi

    1. hemopoiesis Source: MGI
    2. negative regulation of granulocyte differentiation Source: MGI
    3. positive regulation of cell proliferation Source: MGI
    4. positive regulation of G1/S transition of mitotic cell cycle Source: MGI
    5. positive regulation of protein catabolic process Source: MGI
    6. proteasome-mediated ubiquitin-dependent protein catabolic process Source: MGI
    7. regulation of DNA damage checkpoint Source: MGI
    8. regulation of nucleotide-excision repair Source: MGI
    9. regulation of protein metabolic process Source: MGI
    10. somatic stem cell maintenance Source: MGI
    11. ubiquitin-dependent protein catabolic process Source: MGI

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    Putative uncharacterized proteinImported
    Gene namesi
    Name:Cul4aImported
    OrganismiMus musculus (Mouse)Imported
    Taxonomic identifieri10090 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus

    Organism-specific databases

    MGIiMGI:1914487. Cul4a.

    Subcellular locationi

    GO - Cellular componenti

    1. Cul4A-RING E3 ubiquitin ligase complex Source: Ensembl

    Expressioni

    Gene expression databases

    ArrayExpressiQ9CW15.
    BgeeiQ9CW15.
    GenevestigatoriQ9CW15.

    Structurei

    3D structure databases

    ProteinModelPortaliQ9CW15.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the cullin family.UniRule annotation

    Phylogenomic databases

    HOVERGENiHBG074085.
    InParanoidiQ9CW15.

    Family and domain databases

    Gene3Di1.10.10.10. 2 hits.
    InterProiIPR016157. Cullin_CS.
    IPR016158. Cullin_homology.
    IPR001373. Cullin_N.
    IPR019559. Cullin_neddylation_domain.
    IPR011991. WHTH_DNA-bd_dom.
    [Graphical view]
    PfamiPF00888. Cullin. 1 hit.
    PF10557. Cullin_Nedd8. 1 hit.
    [Graphical view]
    SMARTiSM00884. Cullin_Nedd8. 1 hit.
    [Graphical view]
    SUPFAMiSSF75632. SSF75632. 1 hit.
    PROSITEiPS01256. CULLIN_1. 1 hit.
    PS50069. CULLIN_2. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Fragment.

    Q9CW15-1 [UniParc]FASTAAdd to Basket

    « Hide

    KTFYLGKHSG RKLQWQTTLG HAVLKADFKE GKKEFQVSLF QTLVLLMFNE    50
    GDGFSFEEIK MATGIEDSEL RRTLQSLACG KARVLIKSPK GKEVEDGDKF 100
    IFNADFKHKL FRIKINQIQM KETVEEQVST TERVFQDRQY QIDAAIVRIM 150
    KMRKTLGHNL LVSELYNQLK FPVKPGDLKK RIESLIDRDY MERDKDSPNQ 200
    YHYVA 205
    Length:205
    Mass (Da):23,941
    Last modified:June 1, 2001 - v1
    Checksum:i3950BCC9BA28CCFB
    GO

    Experimental Info

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Non-terminal residuei1 – 11Imported

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AK005426 mRNA. Translation: BAB24020.1.
    UniGeneiMm.212861.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AK005426 mRNA. Translation: BAB24020.1 .
    UniGenei Mm.212861.

    3D structure databases

    ProteinModelPortali Q9CW15.
    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Organism-specific databases

    MGIi MGI:1914487. Cul4a.

    Phylogenomic databases

    HOVERGENi HBG074085.
    InParanoidi Q9CW15.

    Miscellaneous databases

    ChiTaRSi CUL4A. mouse.
    SOURCEi Search...

    Gene expression databases

    ArrayExpressi Q9CW15.
    Bgeei Q9CW15.
    Genevestigatori Q9CW15.

    Family and domain databases

    Gene3Di 1.10.10.10. 2 hits.
    InterProi IPR016157. Cullin_CS.
    IPR016158. Cullin_homology.
    IPR001373. Cullin_N.
    IPR019559. Cullin_neddylation_domain.
    IPR011991. WHTH_DNA-bd_dom.
    [Graphical view ]
    Pfami PF00888. Cullin. 1 hit.
    PF10557. Cullin_Nedd8. 1 hit.
    [Graphical view ]
    SMARTi SM00884. Cullin_Nedd8. 1 hit.
    [Graphical view ]
    SUPFAMi SSF75632. SSF75632. 1 hit.
    PROSITEi PS01256. CULLIN_1. 1 hit.
    PS50069. CULLIN_2. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "High-efficiency full-length cDNA cloning."
      Carninci P., Hayashizaki Y.
      Methods Enzymol. 303:19-44(1999) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE.
      Strain: C57BL/6JImported.
      Tissue: PlacentaImported.
    2. "Normalization and subtraction of cap-trapper-selected cDNAs to prepare full-length cDNA libraries for rapid discovery of new genes."
      Carninci P., Shibata Y., Hayatsu N., Sugahara Y., Shibata K., Itoh M., Konno H., Okazaki Y., Muramatsu M., Hayashizaki Y.
      Genome Res. 10:1617-1630(2000) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE.
      Strain: C57BL/6JImported.
      Tissue: PlacentaImported.
    3. Cited for: NUCLEOTIDE SEQUENCE.
      Strain: C57BL/6JImported.
      Tissue: PlacentaImported.
    4. Cited for: NUCLEOTIDE SEQUENCE.
      Strain: C57BL/6JImported.
      Tissue: PlacentaImported.
    5. "Functional annotation of a full-length mouse cDNA collection."
      The RIKEN Genome Exploration Research Group Phase II Team and the FANTOM Consortium
      Nature 409:685-690(2001)
      Cited for: NUCLEOTIDE SEQUENCE.
      Strain: C57BL/6JImported.
      Tissue: PlacentaImported.
    6. "Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs."
      The FANTOM Consortium and the RIKEN Genome Exploration Research Group Phase I and II Team
      Nature 420:563-573(2002)
      Cited for: NUCLEOTIDE SEQUENCE.
      Strain: C57BL/6JImported.
      Tissue: PlacentaImported.
    7. "The Transcriptional Landscape of the Mammalian Genome."
      The FANTOM Consortium, Riken Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group)
      Science 309:1559-1563(2005)
      Cited for: NUCLEOTIDE SEQUENCE.
      Strain: C57BL/6JImported.
      Tissue: PlacentaImported.
    8. Cited for: NUCLEOTIDE SEQUENCE.
      Strain: C57BL/6JImported.
      Tissue: PlacentaImported.

    Entry informationi

    Entry nameiQ9CW15_MOUSE
    AccessioniPrimary (citable) accession number: Q9CW15
    Entry historyi
    Integrated into UniProtKB/TrEMBL: June 1, 2001
    Last sequence update: June 1, 2001
    Last modified: October 1, 2014
    This is version 81 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)