Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Receptor protein serine/threonine kinase

Gene

Tgfbr1

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

Catalytic activityi

ATP + [receptor-protein] = ADP + [receptor-protein] phosphate.SAAS annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionKinase, ReceptorSAAS annotation, Serine/threonine-protein kinaseSAAS annotation, Transferase
LigandATP-bindingSAAS annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Receptor protein serine/threonine kinaseSAAS annotation (EC:2.7.11.30SAAS annotation)
Gene namesi
Name:Tgfbr1Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus

Organism-specific databases

MGIiMGI:98728. Tgfbr1.

Subcellular locationi

Keywords - Cellular componenti

Membrane

PTM / Processingi

Proteomic databases

PaxDbiQ9CVP4.
PeptideAtlasiQ9CVP4.
PRIDEiQ9CVP4.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini1 – 207Protein kinaseInterPro annotationAdd BLAST207

Sequence similaritiesi

Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily.SAAS annotation

Keywords - Domaini

Transmembrane, Transmembrane helixSAAS annotation

Phylogenomic databases

eggNOGiKOG2052. Eukaryota.
ENOG410XQT0. LUCA.
HOGENOMiHOG000230587.
HOVERGENiHBG104975.

Family and domain databases

InterProiView protein in InterPro
IPR011009. Kinase-like_dom.
IPR000719. Prot_kinase_dom.
IPR008271. Ser/Thr_kinase_AS.
IPR000333. TGFB_receptor.
PANTHERiPTHR23255. PTHR23255. 1 hit.
PfamiView protein in Pfam
PF00069. Pkinase. 1 hit.
SMARTiView protein in SMART
SM00220. S_TKc. 1 hit.
SUPFAMiSSF56112. SSF56112. 1 hit.
PROSITEiView protein in PROSITE
PS50011. PROTEIN_KINASE_DOM. 1 hit.
PS00108. PROTEIN_KINASE_ST. 1 hit.

Sequencei

Sequence statusi: Fragment.

Q9CVP4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
FDYLNRYTVT VEGMIKLALS TASGLAHLHM EIVGTQGKPA IAHRDLKSKN
60 70 80 90 100
ILVKKNGTCC IADLGLAVRH DSATDTIDIA PNHRVGTKRY MAPEVLDDSI
110 120 130 140 150
NMKHFESFKR ADIYAMGLVF WEIARRCSIG GIHEDYQLPY YDLVPSDPSV
160 170 180 190 200
EEMRKVVCEQ KLRPNIPNRW QSCEALRVMA KIMRECWYAN GAARLTALRI
210
KKTLSQLSQQ EGIKM
Length:215
Mass (Da):24,353
Last modified:June 1, 2001 - v1
Checksum:i52E9ACE05F802F2D
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei1Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK007125 mRNA. Translation: BAB24865.1.
UniGeneiMm.197552.

Similar proteinsi

Entry informationi

Entry nameiQ9CVP4_MOUSE
AccessioniPrimary (citable) accession number: Q9CVP4
Entry historyiIntegrated into UniProtKB/TrEMBL: June 1, 2001
Last sequence update: June 1, 2001
Last modified: August 30, 2017
This is version 112 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)