Skip Header

You are using a version of Internet Explorer that may not display all features of this website. Please upgrade to a modern browser.
Contribute Send feedback
Read comments (?) or add your own

Q9CU96 (Q9CU96_MOUSE) Unreviewed, UniProtKB/TrEMBL

Last modified February 19, 2014. Version 74. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry infoCustomize order

Names and origin

Protein names
Gene names
Name:Pdgfa MGI 97527
OrganismMus musculus (Mouse) EMBL BAB30622.1
Taxonomic identifier10090 [NCBI]
Taxonomic lineageEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus

Protein attributes

Sequence length118 AA.
Sequence statusFragment.
Protein existenceEvidence at transcript level

General annotation (Comments)

Sequence similarities

Belongs to the PDGF/VEGF growth factor family. RuleBase RU003818

Ontologies

Keywords
   Molecular functionGrowth factor SAAS SAAS000072 RuleBase RU003818
Mitogen RuleBase RU003819
Gene Ontology (GO)
   Biological_processactin cytoskeleton organization

Inferred from direct assay PubMed 12176888. Source: MGI

angiogenesis

Inferred from direct assay PubMed 12101409. Source: MGI

blood coagulation

Inferred from Biological aspect of Ancestor. Source: RefGenome

cell projection assembly

Inferred from direct assay PubMed 12176888. Source: MGI

hair follicle development

Inferred from mutant phenotype PubMed 10331973. Source: MGI

lung alveolus development

Inferred from mutant phenotype PubMed 11803579. Source: MGI

organ morphogenesis

Inferred from mutant phenotype PubMed 14522834. Source: MGI

platelet-derived growth factor receptor signaling pathway

Inferred from Biological aspect of Ancestor. Source: RefGenome

positive regulation of ERK1 and ERK2 cascade

Inferred from Biological aspect of Ancestor. Source: RefGenome

positive regulation of MAP kinase activity

Inferred from Biological aspect of Ancestor. Source: RefGenome

positive regulation of cell division

Inferred from electronic annotation. Source: UniProtKB-KW

positive regulation of cell migration

Inferred from Biological aspect of Ancestor. Source: RefGenome

positive regulation of mesenchymal cell proliferation

Inferred from mutant phenotype PubMed 10331973. Source: MGI

positive regulation of phosphatidylinositol 3-kinase signaling

Inferred from Biological aspect of Ancestor. Source: RefGenome

positive regulation of protein autophosphorylation

Inferred from Biological aspect of Ancestor. Source: RefGenome

regulation of branching involved in salivary gland morphogenesis by epithelial-mesenchymal signaling

Inferred from mutant phenotype PubMed 18559345. Source: MGI

regulation of peptidyl-tyrosine phosphorylation

Inferred from direct assay PubMed 11940581. Source: MGI

   Cellular_componentmembrane

Inferred from electronic annotation. Source: InterPro

microvillus

Inferred from direct assay PubMed 12101409. Source: MGI

   Molecular_functionplatelet-derived growth factor receptor binding

Inferred from Biological aspect of Ancestor. Source: RefGenome

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Experimental info

Non-terminal residue11 EMBL BAB30622.1

Sequences

Sequence LengthMass (Da)Tools
Q9CU96 [UniParc].

Last modified June 1, 2001. Version 1.
Checksum: 00B514B7C6E050D6

FASTA11813,551
        10         20         30         40         50         60 
NVPIRRKRSI EEAIPAVCKT RTVIYEIPRS QVDPTSANFL IWPPCVEVKR CTGCCNTSSV 

        70         80         90        100        110 
KCQPSRVHHR SVKVAKVEYV RKKPKLKEVQ VRLEEHLECA CATSNLNPDH REEETDVR 

« Hide

References

[1]"High-efficiency full-length cDNA cloning."
Carninci P., Hayashizaki Y.
Methods Enzymol. 303:19-44(1999) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE.
Strain: C57BL/6J EMBL BAB30622.1.
Tissue: Ovary and uterus EMBL BAB30622.1.
[2]"Normalization and subtraction of cap-trapper-selected cDNAs to prepare full-length cDNA libraries for rapid discovery of new genes."
Carninci P., Shibata Y., Hayatsu N., Sugahara Y., Shibata K., Itoh M., Konno H., Okazaki Y., Muramatsu M., Hayashizaki Y.
Genome Res. 10:1617-1630(2000) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE.
Strain: C57BL/6J EMBL BAB30622.1.
Tissue: Ovary and uterus EMBL BAB30622.1.
[3]"RIKEN integrated sequence analysis (RISA) system--384-format sequencing pipeline with 384 multicapillary sequencer."
Shibata K., Itoh M., Aizawa K., Nagaoka S., Sasaki N., Carninci P., Konno H., Akiyama J., Nishi K., Kitsunai T., Tashiro H., Itoh M., Sumi N., Ishii Y., Nakamura S., Hazama M., Nishine T., Harada A. expand/collapse author list , Yamamoto R., Matsumoto H., Sakaguchi S., Ikegami T., Kashiwagi K., Fujiwake S., Inoue K., Togawa Y., Izawa M., Ohara E., Watahiki M., Yoneda Y., Ishikawa T., Ozawa K., Tanaka T., Matsuura S., Kawai J., Okazaki Y., Muramatsu M., Inoue Y., Kira A., Hayashizaki Y.
Genome Res. 10:1757-1771(2000) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE.
Strain: C57BL/6J EMBL BAB30622.1.
Tissue: Ovary and uterus EMBL BAB30622.1.
[4]Adachi J., Aizawa K., Akahira S., Akimura T., Arai A., Aono H., Arakawa T., Bono H., Carninci P., Fukuda S., Fukunishi Y., Furuno M., Hanagaki T., Hara A., Hayatsu N., Hiramoto K., Hiraoka T., Hori F. expand/collapse author list , Imotani K., Ishii Y., Itoh M., Izawa M., Kasukawa T., Kato H., Kawai J., Kojima Y., Konno H., Kouda M., Koya S., Kurihara C., Matsuyama T., Miyazaki A., Nishi K., Nomura K., Numazaki R., Ohno M., Okazaki Y., Okido T., Owa C., Saito H., Saito R., Sakai C., Sakai K., Sano H., Sasaki D., Shibata K., Shibata Y., Shinagawa A., Shiraki T., Sogabe Y., Suzuki H., Tagami M., Tagawa A., Takahashi F., Tanaka T., Tejima Y., Toya T., Yamamura T., Yasunishi A., Yoshida K., Yoshino M., Muramatsu M., Hayashizaki Y.
Submitted (JUL-2000) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE.
Strain: C57BL/6J EMBL BAB30622.1.
Tissue: Ovary and uterus EMBL BAB30622.1.
[5]"Functional annotation of a full-length mouse cDNA collection."
The RIKEN Genome Exploration Research Group Phase II Team and the FANTOM Consortium
Nature 409:685-690(2001)
Cited for: NUCLEOTIDE SEQUENCE.
Strain: C57BL/6J EMBL BAB30622.1.
Tissue: Ovary and uterus EMBL BAB30622.1.
[6]"Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs."
The FANTOM Consortium and the RIKEN Genome Exploration Research Group Phase I and II Team
Nature 420:563-573(2002)
Cited for: NUCLEOTIDE SEQUENCE.
Strain: C57BL/6J EMBL BAB30622.1.
Tissue: Ovary and uterus EMBL BAB30622.1.
[7]"The Transcriptional Landscape of the Mammalian Genome."
The FANTOM Consortium, Riken Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group)
Science 309:1559-1563(2005)
Cited for: NUCLEOTIDE SEQUENCE.
Strain: C57BL/6J EMBL BAB30622.1.
Tissue: Ovary and uterus EMBL BAB30622.1.
[8]"Antisense Transcription in the Mammalian Transcriptome."
RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group) and the FANTOM Consortium
Science 309:1564-1566(2005) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE.
Strain: C57BL/6J EMBL BAB30622.1.
Tissue: Ovary and uterus EMBL BAB30622.1.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AK017169 mRNA. Translation: BAB30622.1.
UniGeneMm.2675.

3D structure databases

ProteinModelPortalQ9CU96.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING10090.ENSMUSP00000038870.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Organism-specific databases

MGIMGI:97527. Pdgfa.

Phylogenomic databases

HOVERGENHBG053546.

Gene expression databases

GenevestigatorQ9CU96.

Family and domain databases

InterProIPR023581. PD_growth_factor_CS.
IPR000072. PDGF/VEGF_dom.
[Graphical view]
PfamPF00341. PDGF. 1 hit.
[Graphical view]
SMARTSM00141. PDGF. 1 hit.
[Graphical view]
PROSITEPS00249. PDGF_1. 1 hit.
PS50278. PDGF_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Other

SOURCESearch...

Entry information

Entry nameQ9CU96_MOUSE
AccessionPrimary (citable) accession number: Q9CU96
Entry history
Integrated into UniProtKB/TrEMBL: June 1, 2001
Last sequence update: June 1, 2001
Last modified: February 19, 2014
This is version 74 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)