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Q9CU96

- Q9CU96_MOUSE

UniProt

Q9CU96 - Q9CU96_MOUSE

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Protein
Submitted name:

Putative uncharacterized protein

Gene

Pdgfa

Organism
Mus musculus (Mouse)
Status
Unreviewed - Annotation score: 5 out of 5- Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

  1. platelet-derived growth factor receptor binding Source: RefGenome

GO - Biological processi

  1. actin cytoskeleton organization Source: MGI
  2. angiogenesis Source: MGI
  3. blood coagulation Source: RefGenome
  4. cell projection assembly Source: MGI
  5. hair follicle development Source: MGI
  6. lung alveolus development Source: MGI
  7. organ morphogenesis Source: MGI
  8. platelet-derived growth factor receptor signaling pathway Source: RefGenome
  9. positive regulation of cell division Source: UniProtKB-KW
  10. positive regulation of cell migration Source: RefGenome
  11. positive regulation of cell proliferation Source: MGI
  12. positive regulation of ERK1 and ERK2 cascade Source: RefGenome
  13. positive regulation of MAP kinase activity Source: RefGenome
  14. positive regulation of mesenchymal cell proliferation Source: MGI
  15. positive regulation of phosphatidylinositol 3-kinase signaling Source: RefGenome
  16. positive regulation of protein autophosphorylation Source: RefGenome
  17. regulation of branching involved in salivary gland morphogenesis by epithelial-mesenchymal signaling Source: MGI
  18. regulation of peptidyl-tyrosine phosphorylation Source: MGI
  19. skin development Source: MGI
Complete GO annotation...

Keywords - Molecular functioni

Growth factorUniRule annotationSAAS annotation, MitogenUniRule annotation

Names & Taxonomyi

Protein namesi
Submitted name:
Putative uncharacterized proteinImported
Gene namesi
Name:PdgfaImported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus

Organism-specific databases

MGIiMGI:97527. Pdgfa.

Subcellular locationi

GO - Cellular componenti

  1. membrane Source: InterPro
  2. microvillus Source: MGI
Complete GO annotation...

Expressioni

Gene expression databases

GenevestigatoriQ9CU96.

Interactioni

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000038870.

Structurei

3D structure databases

ProteinModelPortaliQ9CU96.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the PDGF/VEGF growth factor family.UniRule annotation

Phylogenomic databases

HOVERGENiHBG053546.

Family and domain databases

Gene3Di2.10.90.10. 1 hit.
InterProiIPR029034. Cystine-knot_cytokine.
IPR023581. PD_growth_factor_CS.
IPR000072. PDGF/VEGF_dom.
[Graphical view]
PfamiPF00341. PDGF. 1 hit.
[Graphical view]
SMARTiSM00141. PDGF. 1 hit.
[Graphical view]
SUPFAMiSSF57501. SSF57501. 1 hit.
PROSITEiPS00249. PDGF_1. 1 hit.
PS50278. PDGF_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Fragment.

Q9CU96-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
NVPIRRKRSI EEAIPAVCKT RTVIYEIPRS QVDPTSANFL IWPPCVEVKR
60 70 80 90 100
CTGCCNTSSV KCQPSRVHHR SVKVAKVEYV RKKPKLKEVQ VRLEEHLECA
110
CATSNLNPDH REEETDVR
Length:118
Mass (Da):13,551
Last modified:June 1, 2001 - v1
Checksum:i00B514B7C6E050D6
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei1 – 11Imported

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AK017169 mRNA. Translation: BAB30622.1.
UniGeneiMm.2675.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AK017169 mRNA. Translation: BAB30622.1 .
UniGenei Mm.2675.

3D structure databases

ProteinModelPortali Q9CU96.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 10090.ENSMUSP00000038870.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Organism-specific databases

MGIi MGI:97527. Pdgfa.

Phylogenomic databases

HOVERGENi HBG053546.

Miscellaneous databases

SOURCEi Search...

Gene expression databases

Genevestigatori Q9CU96.

Family and domain databases

Gene3Di 2.10.90.10. 1 hit.
InterProi IPR029034. Cystine-knot_cytokine.
IPR023581. PD_growth_factor_CS.
IPR000072. PDGF/VEGF_dom.
[Graphical view ]
Pfami PF00341. PDGF. 1 hit.
[Graphical view ]
SMARTi SM00141. PDGF. 1 hit.
[Graphical view ]
SUPFAMi SSF57501. SSF57501. 1 hit.
PROSITEi PS00249. PDGF_1. 1 hit.
PS50278. PDGF_2. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "High-efficiency full-length cDNA cloning."
    Carninci P., Hayashizaki Y.
    Methods Enzymol. 303:19-44(1999) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
    Tissue: Ovary and uterusImported.
  2. "Normalization and subtraction of cap-trapper-selected cDNAs to prepare full-length cDNA libraries for rapid discovery of new genes."
    Carninci P., Shibata Y., Hayatsu N., Sugahara Y., Shibata K., Itoh M., Konno H., Okazaki Y., Muramatsu M., Hayashizaki Y.
    Genome Res. 10:1617-1630(2000) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
    Tissue: Ovary and uterusImported.
  3. Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
    Tissue: Ovary and uterusImported.
  4. Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
    Tissue: Ovary and uterusImported.
  5. "Functional annotation of a full-length mouse cDNA collection."
    The RIKEN Genome Exploration Research Group Phase II Team and the FANTOM Consortium
    Nature 409:685-690(2001)
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
    Tissue: Ovary and uterusImported.
  6. "Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs."
    The FANTOM Consortium and the RIKEN Genome Exploration Research Group Phase I and II Team
    Nature 420:563-573(2002)
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
    Tissue: Ovary and uterusImported.
  7. "The Transcriptional Landscape of the Mammalian Genome."
    The FANTOM Consortium, Riken Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group)
    Science 309:1559-1563(2005)
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
    Tissue: Ovary and uterusImported.
  8. Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
    Tissue: Ovary and uterusImported.

Entry informationi

Entry nameiQ9CU96_MOUSE
AccessioniPrimary (citable) accession number: Q9CU96
Entry historyi
Integrated into UniProtKB/TrEMBL: June 1, 2001
Last sequence update: June 1, 2001
Last modified: October 29, 2014
This is version 78 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)