Q9CTT8 (Q9CTT8_MOUSE) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Putative uncharacterized protein EMBL BAB32083.3

Gene names

Name:

Ryr2 MGI 99685

Organism

Mus musculus (Mouse) EMBL BAB32083.3

Taxonomic identifier

10090 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Euarchontoglires › Glires › Rodentia › Sciurognathi › Muroidea › Muridae › Murinae › Mus › Mus

Protein attributes

Sequence length	163 AA.
Sequence status	Fragment.
Protein existence	Evidence at transcript level

Ontologies

Gene Ontology (GO)
Biological_process	BMP signaling pathway Inferred from direct assay PubMed 17360443. Source: MGI canonical Wnt receptor signaling pathway Inferred from direct assay PubMed 17360443. Source: MGI cardiac muscle contraction Inferred from electronic annotation. Source: Compara cardiac muscle hypertrophy Inferred from mutant phenotype PubMed 17431507. Source: MGI cellular response to caffeine Inferred from direct assay PubMed 12089338. Source: MGI detection of calcium ion Inferred from electronic annotation. Source: Compara intrinsic apoptotic signaling pathway in response to osmotic stress Inferred from electronic annotation. Source: Compara left ventricular cardiac muscle tissue morphogenesis Inferred from mutant phenotype PubMed 17431507. Source: MGI positive regulation of heart rate Inferred from mutant phenotype PubMed 12089338PubMed 17431507. Source: MGI release of sequestered calcium ion into cytosol by sarcoplasmic reticulum Inferred from mutant phenotype PubMed 12089338. Source: MGI response to redox state Inferred from electronic annotation. Source: Compara
Cellular_component	Z disc Inferred from direct assay PubMed 16204356PubMed 19383796. Source: MGI calcium channel complex Inferred from electronic annotation. Source: Compara integral to membrane Inferred by curator PubMed 14593104. Source: MGI protein complex Inferred from sequence orthology PubMed 18468998. Source: MGI sarcoplasmic reticulum membrane Inferred from direct assay PubMed 14592808PubMed 16481613. Source: MGI
Molecular_function	calmodulin binding Inferred from direct assay PubMed 17431507. Source: MGI ryanodine-sensitive calcium-release channel activity Inferred from direct assay PubMed 14593104PubMed 17431507. Source: MGI suramin binding Inferred from electronic annotation. Source: Compara
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Experimental info
	Non-terminal residue	163	1	EMBL BAB32083.3

Sequences

	Sequence		Length	Mass (Da)
	Q9CTT8 [UniParc]. Last modified October 11, 2005. Version 3. Checksum: 254B5014B85538BC	FASTA	163	18,013
	10 20 30 40 50 60 MADAGEGEDE IQFLRTDDEV VLQCTATIHK EQQKLCLAAE GFGNRLCFLE STSNSKNVPP 70 80 90 100 110 120 DLSICTFVLE QSLSVRALQE MLANTVEKSE GKFMMKTAQG GGHRTLLYGH AILLRHSYSG 130 140 150 160 MYLCCLSTSR SSTDKLAFDV GLQEDTTGEA CWWTIHPASK QRS

References

[1]	"High-efficiency full-length cDNA cloning." Carninci P., Hayashizaki Y. Methods Enzymol. 303:19-44(1999) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE. Strain: C57BL/6J EMBL BAB32083.3. Tissue: Diencephalon EMBL BAB32083.3.
[2]	"Normalization and subtraction of cap-trapper-selected cDNAs to prepare full-length cDNA libraries for rapid discovery of new genes." Carninci P., Shibata Y., Hayatsu N., Sugahara Y., Shibata K., Itoh M., Konno H., Okazaki Y., Muramatsu M., Hayashizaki Y. Genome Res. 10:1617-1630(2000) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE. Strain: C57BL/6J EMBL BAB32083.3. Tissue: Diencephalon EMBL BAB32083.3.
[3]	"RIKEN integrated sequence analysis (RISA) system--384-format sequencing pipeline with 384 multicapillary sequencer." Shibata K., Itoh M., Aizawa K., Nagaoka S., Sasaki N., Carninci P., Konno H., Akiyama J., Nishi K., Kitsunai T., Tashiro H., Itoh M., Sumi N., Ishii Y., Nakamura S., Hazama M., Nishine T., Harada A. , Yamamoto R., Matsumoto H., Sakaguchi S., Ikegami T., Kashiwagi K., Fujiwake S., Inoue K., Togawa Y., Izawa M., Ohara E., Watahiki M., Yoneda Y., Ishikawa T., Ozawa K., Tanaka T., Matsuura S., Kawai J., Okazaki Y., Muramatsu M., Inoue Y., Kira A., Hayashizaki Y. Genome Res. 10:1757-1771(2000) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE. Strain: C57BL/6J EMBL BAB32083.3. Tissue: Diencephalon EMBL BAB32083.3.
[4]	Adachi J., Aizawa K., Akahira S., Akimura T., Arai A., Aono H., Arakawa T., Bono H., Carninci P., Fukuda S., Fukunishi Y., Furuno M., Hanagaki T., Hara A., Hayatsu N., Hiramoto K., Hiraoka T., Hori F. , Imotani K., Ishii Y., Itoh M., Izawa M., Kasukawa T., Kato H., Kawai J., Kojima Y., Konno H., Kouda M., Koya S., Kurihara C., Matsuyama T., Miyazaki A., Nishi K., Nomura K., Numazaki R., Ohno M., Okazaki Y., Okido T., Owa C., Saito H., Saito R., Sakai C., Sakai K., Sano H., Sasaki D., Shibata K., Shibata Y., Shinagawa A., Shiraki T., Sogabe Y., Suzuki H., Tagami M., Tagawa A., Takahashi F., Tanaka T., Tejima Y., Toya T., Yamamura T., Yasunishi A., Yoshida K., Yoshino M., Muramatsu M., Hayashizaki Y. Submitted (AUG-2000) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE. Strain: C57BL/6J EMBL BAB32083.3. Tissue: Diencephalon EMBL BAB32083.3.
[5]	"Functional annotation of a full-length mouse cDNA collection." The RIKEN Genome Exploration Research Group Phase II Team and the FANTOM Consortium Nature 409:685-690(2001) Cited for: NUCLEOTIDE SEQUENCE. Strain: C57BL/6J EMBL BAB32083.3. Tissue: Diencephalon EMBL BAB32083.3.
[6]	"Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs." The FANTOM Consortium and the RIKEN Genome Exploration Research Group Phase I and II Team Nature 420:563-573(2002) Cited for: NUCLEOTIDE SEQUENCE. Strain: C57BL/6J EMBL BAB32083.3. Tissue: Diencephalon EMBL BAB32083.3.
[7]	"The Transcriptional Landscape of the Mammalian Genome." The FANTOM Consortium, Riken Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group) Science 309:1559-1563(2005) Cited for: NUCLEOTIDE SEQUENCE. Strain: C57BL/6J EMBL BAB32083.3. Tissue: Diencephalon EMBL BAB32083.3.
[8]	"Antisense Transcription in the Mammalian Transcriptome." RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group) and the FANTOM Consortium Science 309:1564-1566(2005) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE. Strain: C57BL/6J EMBL BAB32083.3. Tissue: Diencephalon EMBL BAB32083.3.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AK020368 mRNA. Translation: BAB32083.3.
IPI	IPI00987661.
UniGene	Mm.239871.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
STRING	Q9CTT8.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Organism-specific databases
MGI	MGI:99685. Ryr2.
Phylogenomic databases
HOVERGEN	HBG083019.
InParanoid	Q9CTT8.
Gene expression databases
ArrayExpress	Q9CTT8.
Bgee	Q9CTT8.
Genevestigator	Q9CTT8.
Family and domain databases
InterPro	IPR014821. Ins145_P3_rcpt. IPR016093. MIR_motif. IPR013333. Ryan_recept. [Graphical view]
Pfam	PF08709. Ins145_P3_rec. 1 hit. [Graphical view]
PRINTS	PR00795. RYANODINER.
PROSITE	PS50919. MIR. 1 hit. [Graphical view]
ProtoNet	Search...
Other
SOURCE	Search...

Entry information

Entry name

Q9CTT8_MOUSE

Accession

Primary (citable) accession number: Q9CTT8

Entry history

Integrated into UniProtKB/TrEMBL:	June 1, 2001
Last sequence update:	October 11, 2005
Last modified:	April 3, 2013
This is version 60 of the entry and version 3 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)