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Q9CTT8

- Q9CTT8_MOUSE

UniProt

Q9CTT8 - Q9CTT8_MOUSE

Protein
Submitted name:

Putative uncharacterized protein

Gene

Ryr2

Organism
Mus musculus (Mouse)
Status
Unreviewed - Annotation score: 5 out of 5- Experimental evidence at transcript leveli
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    • History
      Entry version 72 (01 Oct 2014)
      Sequence version 3 (11 Oct 2005)
      Previous versions | rss
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    Functioni

    GO - Molecular functioni

    1. binding Source: MGI
    2. calcium-induced calcium release activity Source: Ensembl
    3. calmodulin binding Source: MGI
    4. protein binding Source: MGI
    5. ryanodine-sensitive calcium-release channel activity Source: MGI
    6. suramin binding Source: Ensembl

    GO - Biological processi

    1. BMP signaling pathway Source: MGI
    2. calcium ion transmembrane transport Source: MGI
    3. calcium ion transport Source: MGI
    4. calcium-mediated signaling using intracellular calcium source Source: Ensembl
    5. canonical Wnt signaling pathway Source: MGI
    6. cardiac muscle contraction Source: Ensembl
    7. cardiac muscle hypertrophy Source: MGI
    8. cellular response to caffeine Source: MGI
    9. cytosolic calcium ion transport Source: MGI
    10. detection of calcium ion Source: Ensembl
    11. establishment of protein localization to endoplasmic reticulum Source: Ensembl
    12. left ventricular cardiac muscle tissue morphogenesis Source: MGI
    13. positive regulation of calcium-transporting ATPase activity Source: Ensembl
    14. positive regulation of heart rate Source: MGI
    15. positive regulation of sequestering of calcium ion Source: Ensembl
    16. regulation of cardiac muscle contraction Source: Ensembl
    17. release of sequestered calcium ion into cytosol by sarcoplasmic reticulum Source: MGI
    18. response to caffeine Source: MGI
    19. response to redox state Source: Ensembl
    20. type B pancreatic cell apoptotic process Source: Ensembl

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    Putative uncharacterized proteinImported
    Gene namesi
    Name:Ryr2Imported
    OrganismiMus musculus (Mouse)Imported
    Taxonomic identifieri10090 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus

    Organism-specific databases

    MGIiMGI:99685. Ryr2.

    Subcellular locationi

    GO - Cellular componenti

    1. calcium channel complex Source: Ensembl
    2. integral component of membrane Source: MGI
    3. membrane Source: MGI
    4. protein complex Source: MGI
    5. sarcoplasmic reticulum Source: MGI
    6. sarcoplasmic reticulum membrane Source: MGI
    7. smooth endoplasmic reticulum Source: MGI
    8. Z disc Source: MGI

    Expressioni

    Gene expression databases

    ArrayExpressiQ9CTT8.
    BgeeiQ9CTT8.
    GenevestigatoriQ9CTT8.

    Family & Domainsi

    Phylogenomic databases

    HOVERGENiHBG083019.
    InParanoidiQ9CTT8.

    Family and domain databases

    InterProiIPR014821. Ins145_P3_rcpt.
    IPR016093. MIR_motif.
    IPR013333. Ryan_recept.
    IPR015925. Ryanodine_recept-rel.
    [Graphical view]
    PANTHERiPTHR13715. PTHR13715. 1 hit.
    PfamiPF08709. Ins145_P3_rec. 1 hit.
    [Graphical view]
    PRINTSiPR00795. RYANODINER.
    PROSITEiPS50919. MIR. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Fragment.

    Q9CTT8-1 [UniParc]FASTAAdd to Basket

    « Hide

    MADAGEGEDE IQFLRTDDEV VLQCTATIHK EQQKLCLAAE GFGNRLCFLE    50
    STSNSKNVPP DLSICTFVLE QSLSVRALQE MLANTVEKSE GKFMMKTAQG 100
    GGHRTLLYGH AILLRHSYSG MYLCCLSTSR SSTDKLAFDV GLQEDTTGEA 150
    CWWTIHPASK QRS 163
    Length:163
    Mass (Da):18,013
    Last modified:October 11, 2005 - v3
    Checksum:i254B5014B85538BC
    GO

    Experimental Info

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Non-terminal residuei163 – 1631Imported

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AK020368 mRNA. Translation: BAB32083.3.
    UniGeneiMm.239871.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AK020368 mRNA. Translation: BAB32083.3 .
    UniGenei Mm.239871.

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Organism-specific databases

    MGIi MGI:99685. Ryr2.

    Phylogenomic databases

    HOVERGENi HBG083019.
    InParanoidi Q9CTT8.

    Miscellaneous databases

    SOURCEi Search...

    Gene expression databases

    ArrayExpressi Q9CTT8.
    Bgeei Q9CTT8.
    Genevestigatori Q9CTT8.

    Family and domain databases

    InterProi IPR014821. Ins145_P3_rcpt.
    IPR016093. MIR_motif.
    IPR013333. Ryan_recept.
    IPR015925. Ryanodine_recept-rel.
    [Graphical view ]
    PANTHERi PTHR13715. PTHR13715. 1 hit.
    Pfami PF08709. Ins145_P3_rec. 1 hit.
    [Graphical view ]
    PRINTSi PR00795. RYANODINER.
    PROSITEi PS50919. MIR. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "High-efficiency full-length cDNA cloning."
      Carninci P., Hayashizaki Y.
      Methods Enzymol. 303:19-44(1999) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE.
      Strain: C57BL/6JImported.
      Tissue: DiencephalonImported.
    2. "Normalization and subtraction of cap-trapper-selected cDNAs to prepare full-length cDNA libraries for rapid discovery of new genes."
      Carninci P., Shibata Y., Hayatsu N., Sugahara Y., Shibata K., Itoh M., Konno H., Okazaki Y., Muramatsu M., Hayashizaki Y.
      Genome Res. 10:1617-1630(2000) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE.
      Strain: C57BL/6JImported.
      Tissue: DiencephalonImported.
    3. Cited for: NUCLEOTIDE SEQUENCE.
      Strain: C57BL/6JImported.
      Tissue: DiencephalonImported.
    4. Cited for: NUCLEOTIDE SEQUENCE.
      Strain: C57BL/6JImported.
      Tissue: DiencephalonImported.
    5. "Functional annotation of a full-length mouse cDNA collection."
      The RIKEN Genome Exploration Research Group Phase II Team and the FANTOM Consortium
      Nature 409:685-690(2001)
      Cited for: NUCLEOTIDE SEQUENCE.
      Strain: C57BL/6JImported.
      Tissue: DiencephalonImported.
    6. "Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs."
      The FANTOM Consortium and the RIKEN Genome Exploration Research Group Phase I and II Team
      Nature 420:563-573(2002)
      Cited for: NUCLEOTIDE SEQUENCE.
      Strain: C57BL/6JImported.
      Tissue: DiencephalonImported.
    7. "The Transcriptional Landscape of the Mammalian Genome."
      The FANTOM Consortium, Riken Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group)
      Science 309:1559-1563(2005)
      Cited for: NUCLEOTIDE SEQUENCE.
      Strain: C57BL/6JImported.
      Tissue: DiencephalonImported.
    8. Cited for: NUCLEOTIDE SEQUENCE.
      Strain: C57BL/6JImported.
      Tissue: DiencephalonImported.

    Entry informationi

    Entry nameiQ9CTT8_MOUSE
    AccessioniPrimary (citable) accession number: Q9CTT8
    Entry historyi
    Integrated into UniProtKB/TrEMBL: June 1, 2001
    Last sequence update: October 11, 2005
    Last modified: October 1, 2014
    This is version 72 of the entry and version 3 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)