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Q9CTT8

- Q9CTT8_MOUSE

UniProt

Q9CTT8 - Q9CTT8_MOUSE

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Protein
Submitted name:

Putative uncharacterized protein

Gene

Ryr2

Organism
Mus musculus (Mouse)
Status
Unreviewed - Annotation score: 5 out of 5- Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

  1. calcium-induced calcium release activity Source: Ensembl
  2. calmodulin binding Source: MGI
  3. organic cyclic compound binding Source: MGI
  4. ryanodine-sensitive calcium-release channel activity Source: MGI
  5. suramin binding Source: Ensembl

GO - Biological processi

  1. BMP signaling pathway Source: MGI
  2. calcium ion transmembrane transport Source: MGI
  3. calcium ion transport Source: MGI
  4. calcium-mediated signaling using intracellular calcium source Source: Ensembl
  5. canonical Wnt signaling pathway Source: MGI
  6. cardiac muscle contraction Source: Ensembl
  7. cardiac muscle hypertrophy Source: MGI
  8. cellular response to caffeine Source: MGI
  9. cytosolic calcium ion transport Source: MGI
  10. detection of calcium ion Source: Ensembl
  11. establishment of protein localization to endoplasmic reticulum Source: Ensembl
  12. left ventricular cardiac muscle tissue morphogenesis Source: MGI
  13. positive regulation of calcium-transporting ATPase activity Source: Ensembl
  14. positive regulation of heart rate Source: MGI
  15. positive regulation of sequestering of calcium ion Source: Ensembl
  16. regulation of cardiac muscle contraction Source: Ensembl
  17. release of sequestered calcium ion into cytosol by sarcoplasmic reticulum Source: MGI
  18. response to caffeine Source: MGI
  19. response to redox state Source: Ensembl
  20. type B pancreatic cell apoptotic process Source: Ensembl
Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
Putative uncharacterized proteinImported
Gene namesi
Name:Ryr2Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus

Organism-specific databases

MGIiMGI:99685. Ryr2.

Subcellular locationi

GO - Cellular componenti

  1. calcium channel complex Source: Ensembl
  2. extracellular vesicular exosome Source: Ensembl
  3. integral component of membrane Source: MGI
  4. membrane Source: MGI
  5. protein complex Source: MGI
  6. sarcoplasmic reticulum Source: MGI
  7. sarcoplasmic reticulum membrane Source: MGI
  8. smooth endoplasmic reticulum Source: MGI
  9. Z disc Source: MGI
Complete GO annotation...

Expressioni

Gene expression databases

BgeeiQ9CTT8.
ExpressionAtlasiQ9CTT8. baseline and differential.
GenevestigatoriQ9CTT8.

Family & Domainsi

Phylogenomic databases

HOVERGENiHBG083019.

Family and domain databases

InterProiIPR014821. Ins145_P3_rcpt.
IPR016093. MIR_motif.
IPR013333. Ryan_recept.
IPR015925. Ryanodine_recept-rel.
[Graphical view]
PANTHERiPTHR13715. PTHR13715. 1 hit.
PfamiPF08709. Ins145_P3_rec. 1 hit.
[Graphical view]
PRINTSiPR00795. RYANODINER.
PROSITEiPS50919. MIR. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Fragment.

Q9CTT8-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MADAGEGEDE IQFLRTDDEV VLQCTATIHK EQQKLCLAAE GFGNRLCFLE
60 70 80 90 100
STSNSKNVPP DLSICTFVLE QSLSVRALQE MLANTVEKSE GKFMMKTAQG
110 120 130 140 150
GGHRTLLYGH AILLRHSYSG MYLCCLSTSR SSTDKLAFDV GLQEDTTGEA
160
CWWTIHPASK QRS
Length:163
Mass (Da):18,013
Last modified:October 11, 2005 - v3
Checksum:i254B5014B85538BC
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei163 – 1631Imported

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK020368 mRNA. Translation: BAB32083.3.
UniGeneiMm.239871.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK020368 mRNA. Translation: BAB32083.3 .
UniGenei Mm.239871.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Organism-specific databases

MGIi MGI:99685. Ryr2.

Phylogenomic databases

HOVERGENi HBG083019.

Miscellaneous databases

SOURCEi Search...

Gene expression databases

Bgeei Q9CTT8.
ExpressionAtlasi Q9CTT8. baseline and differential.
Genevestigatori Q9CTT8.

Family and domain databases

InterProi IPR014821. Ins145_P3_rcpt.
IPR016093. MIR_motif.
IPR013333. Ryan_recept.
IPR015925. Ryanodine_recept-rel.
[Graphical view ]
PANTHERi PTHR13715. PTHR13715. 1 hit.
Pfami PF08709. Ins145_P3_rec. 1 hit.
[Graphical view ]
PRINTSi PR00795. RYANODINER.
PROSITEi PS50919. MIR. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "High-efficiency full-length cDNA cloning."
    Carninci P., Hayashizaki Y.
    Methods Enzymol. 303:19-44(1999) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
    Tissue: DiencephalonImported.
  2. "Normalization and subtraction of cap-trapper-selected cDNAs to prepare full-length cDNA libraries for rapid discovery of new genes."
    Carninci P., Shibata Y., Hayatsu N., Sugahara Y., Shibata K., Itoh M., Konno H., Okazaki Y., Muramatsu M., Hayashizaki Y.
    Genome Res. 10:1617-1630(2000) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
    Tissue: DiencephalonImported.
  3. Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
    Tissue: DiencephalonImported.
  4. Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
    Tissue: DiencephalonImported.
  5. "Functional annotation of a full-length mouse cDNA collection."
    The RIKEN Genome Exploration Research Group Phase II Team and the FANTOM Consortium
    Nature 409:685-690(2001)
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
    Tissue: DiencephalonImported.
  6. "Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs."
    The FANTOM Consortium and the RIKEN Genome Exploration Research Group Phase I and II Team
    Nature 420:563-573(2002)
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
    Tissue: DiencephalonImported.
  7. "The Transcriptional Landscape of the Mammalian Genome."
    The FANTOM Consortium, Riken Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group)
    Science 309:1559-1563(2005)
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
    Tissue: DiencephalonImported.
  8. Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
    Tissue: DiencephalonImported.

Entry informationi

Entry nameiQ9CTT8_MOUSE
AccessioniPrimary (citable) accession number: Q9CTT8
Entry historyi
Integrated into UniProtKB/TrEMBL: June 1, 2001
Last sequence update: October 11, 2005
Last modified: November 26, 2014
This is version 74 of the entry and version 3 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)