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Protein
Submitted name:

Putative uncharacterized protein

Gene

Rb1

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: Annotation score: 5 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

GO - Biological processi

  • cell cycle arrest Source: MGI
  • cell division Source: MGI
  • cell morphogenesis involved in neuron differentiation Source: MGI
  • cellular response to xenobiotic stimulus Source: MGI
  • digestive tract development Source: MGI
  • enucleate erythrocyte differentiation Source: MGI
  • G1/S transition of mitotic cell cycle Source: MGI
  • glial cell apoptotic process Source: MGI
  • hepatocyte apoptotic process Source: MGI
  • maintenance of mitotic sister chromatid cohesion Source: MGI
  • myoblast differentiation Source: MGI
  • negative regulation of cell cycle Source: MGI
  • negative regulation of cell proliferation Source: MGI
  • negative regulation of epithelial cell proliferation Source: MGI
  • negative regulation of G1/S transition of mitotic cell cycle Source: MGI
  • negative regulation of mitotic cell cycle Source: MGI
  • negative regulation of protein kinase activity Source: MGI
  • negative regulation of smoothened signaling pathway Source: MGI
  • negative regulation of transcription, DNA-templated Source: MGI
  • negative regulation of transcription from RNA polymerase II promoter Source: MGI
  • neuron apoptotic process Source: MGI
  • neuron differentiation Source: MGI
  • neuron maturation Source: MGI
  • neuron projection development Source: MGI
  • positive regulation of macrophage differentiation Source: MGI
  • positive regulation of mitotic metaphase/anaphase transition Source: MGI
  • positive regulation of transcription from RNA polymerase II promoter Source: MGI
  • protein localization to chromosome, centromeric region Source: MGI
  • regulation of cell cycle Source: MGI
  • regulation of cohesin localization to chromatin Source: MGI
  • regulation of lipid kinase activity Source: MGI
  • regulation of mitotic cell cycle Source: MGI
  • sister chromatid biorientation Source: MGI
  • skeletal muscle cell differentiation Source: MGI
  • striated muscle cell differentiation Source: MGI
Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
Putative uncharacterized proteinImported
Gene namesi
Name:Rb1Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus

Organism-specific databases

MGIiMGI:97874. Rb1.

Subcellular locationi

GO - Cellular componenti

  • nucleus Source: MGI
  • PML body Source: MGI
  • spindle Source: MGI
  • transcription factor complex Source: MGI
Complete GO annotation...

Interactioni

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000022701.

Structurei

3D structure databases

ProteinModelPortaliQ9CT40.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Family and domain databases

InterProiIPR002720. RB_A.
IPR028309. RB_fam.
IPR024599. RB_N.
[Graphical view]
PANTHERiPTHR13742. PTHR13742. 1 hit.
PfamiPF11934. DUF3452. 1 hit.
PF01858. RB_A. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Fragment.

Q9CT40-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MPPKAPRRAA AAEPPPPPPP PPREDDPAQD SGPEELPLAR LEFEEIEEPE
60 70 80 90 100
FIALCQKLKV PDHVRERAWL TWEKVSSVDG ILEGYIQKKK ELWGICIFIA
110 120 130 140 150
AVDLDEMPFT FTELQKSIET SVYKFFDLLK EIDTSTKVDN AMSRLLKKYN
160 170 180 190 200
VLCALYSKLE RTCELIYLTQ PSSALSTEIN SMLVLKISWI TFLLAKGEVL
210 220 230 240 250
QMEDDLVISF QLMLCVVDYF IKFSPPALLR EPYKTAALPI NGSPRTPRRG
260 270 280 290 300
QNRSARIAKQ LENDTRIIEV LCKEHECNID EVKNVYFKNF IPFINSLGIV
310 320 330 340 350
SSNGLPEVES LSKRYEEVYL KNKDLDARLF LDHDKTLQTD PIDSFETERT
360 370 380 390 400
PRKNNPDEEA NVVTPHTPVR TVMNTIQQLM VILNSASDQP SENLISYFNN

CTVNP
Length:405
Mass (Da):46,221
Last modified:October 11, 2005 - v3
Checksum:iC18B6F9A0565B88C
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei405 – 4051Imported

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK011246 mRNA. Translation: BAB27493.3.
UniGeneiMm.273862.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK011246 mRNA. Translation: BAB27493.3.
UniGeneiMm.273862.

3D structure databases

ProteinModelPortaliQ9CT40.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000022701.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Organism-specific databases

MGIiMGI:97874. Rb1.

Miscellaneous databases

SOURCEiSearch...

Family and domain databases

InterProiIPR002720. RB_A.
IPR028309. RB_fam.
IPR024599. RB_N.
[Graphical view]
PANTHERiPTHR13742. PTHR13742. 1 hit.
PfamiPF11934. DUF3452. 1 hit.
PF01858. RB_A. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "High-efficiency full-length cDNA cloning."
    Carninci P., Hayashizaki Y.
    Methods Enzymol. 303:19-44(1999) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
    Tissue: Whole bodyImported.
  2. "Normalization and subtraction of cap-trapper-selected cDNAs to prepare full-length cDNA libraries for rapid discovery of new genes."
    Carninci P., Shibata Y., Hayatsu N., Sugahara Y., Shibata K., Itoh M., Konno H., Okazaki Y., Muramatsu M., Hayashizaki Y.
    Genome Res. 10:1617-1630(2000) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
    Tissue: Whole bodyImported.
  3. Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
    Tissue: Whole bodyImported.
  4. Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
    Tissue: Whole bodyImported.
  5. "Functional annotation of a full-length mouse cDNA collection."
    The RIKEN Genome Exploration Research Group Phase II Team and the FANTOM Consortium
    Nature 409:685-690(2001)
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
    Tissue: Whole bodyImported.
  6. "Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs."
    The FANTOM Consortium and the RIKEN Genome Exploration Research Group Phase I and II Team
    Nature 420:563-573(2002)
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
    Tissue: Whole bodyImported.
  7. "The Transcriptional Landscape of the Mammalian Genome."
    The FANTOM Consortium, Riken Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group)
    Science 309:1559-1563(2005)
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
    Tissue: Whole bodyImported.
  8. Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
    Tissue: Whole bodyImported.

Entry informationi

Entry nameiQ9CT40_MOUSE
AccessioniPrimary (citable) accession number: Q9CT40
Entry historyi
Integrated into UniProtKB/TrEMBL: June 1, 2001
Last sequence update: October 11, 2005
Last modified: June 24, 2015
This is version 82 of the entry and version 3 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.