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Q9CT40 (Q9CT40_MOUSE) Unreviewed, UniProtKB/TrEMBL

Last modified April 16, 2014. Version 75. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry infoCustomize order

Names and origin

Protein names
Gene names
Name:Rb1 MGI 97874
OrganismMus musculus (Mouse) EMBL BAB27493.3
Taxonomic identifier10090 [NCBI]
Taxonomic lineageEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus

Protein attributes

Sequence length405 AA.
Sequence statusFragment.
Protein existenceEvidence at transcript level

Ontologies

Gene Ontology (GO)
   Biological_processG1/S transition of mitotic cell cycle

Inferred from mutant phenotype PubMed 15831459. Source: MGI

cell cycle arrest

Inferred from mutant phenotype PubMed 15831459. Source: MGI

cell division

Inferred from mutant phenotype PubMed 15843406. Source: MGI

cell morphogenesis involved in neuron differentiation

Inferred from mutant phenotype PubMed 7958874. Source: MGI

digestive tract development

Inferred from mutant phenotype PubMed 17257418. Source: MGI

enucleate erythrocyte differentiation

Inferred from genetic interaction PubMed 15616565. Source: MGI

glial cell apoptotic process

Inferred from mutant phenotype PubMed 11549719. Source: MGI

hepatocyte apoptotic process

Inferred from mutant phenotype PubMed 11549719. Source: MGI

negative regulation of G1/S transition of mitotic cell cycle

Inferred from mutant phenotype PubMed 7958874. Source: MGI

negative regulation of cell cycle

Inferred from mutant phenotype PubMed 12853964. Source: MGI

negative regulation of cell proliferation

Inferred from mutant phenotype PubMed 15843406. Source: MGI

negative regulation of epithelial cell proliferation

Inferred from mutant phenotype PubMed 17257418. Source: MGI

negative regulation of smoothened signaling pathway

Inferred from mutant phenotype PubMed 17257418. Source: MGI

negative regulation of transcription from RNA polymerase II promoter

Inferred from direct assay PubMed 12200151. Source: MGI

negative regulation of transcription, DNA-templated

Inferred from direct assay PubMed 11331592. Source: MGI

neuron apoptotic process

Inferred from mutant phenotype PubMed 11549719PubMed 7958874. Source: MGI

neuron differentiation

Inferred from mutant phenotype PubMed 7958874. Source: MGI

neuron maturation

Inferred from mutant phenotype PubMed 7958874. Source: MGI

neuron projection development

Inferred from mutant phenotype PubMed 7958874. Source: MGI

positive regulation of macrophage differentiation

Inferred from genetic interaction PubMed 15616565. Source: MGI

positive regulation of transcription from RNA polymerase II promoter

Inferred from direct assay PubMed 15701640. Source: MGI

regulation of cell cycle

Inferred from mutant phenotype PubMed 15898111. Source: MGI

skeletal muscle cell differentiation

Inferred from mutant phenotype PubMed 22147266. Source: MGI

striated muscle cell differentiation

Inferred from genetic interaction PubMed 15542848. Source: MGI

transcription, DNA-templated

Inferred from electronic annotation. Source: InterPro

   Cellular_componentnucleus

Inferred from direct assay PubMed 10082561PubMed 15616565PubMed 15701640PubMed 16513252. Source: MGI

spindle

Inferred from direct assay PubMed 15509711. Source: MGI

transcription factor complex

Inferred from direct assay PubMed 10082561. Source: MGI

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Experimental info

Non-terminal residue4051 EMBL BAB27493.3

Sequences

Sequence LengthMass (Da)Tools
Q9CT40 [UniParc].

Last modified October 11, 2005. Version 3.
Checksum: C18B6F9A0565B88C

FASTA40546,221
        10         20         30         40         50         60 
MPPKAPRRAA AAEPPPPPPP PPREDDPAQD SGPEELPLAR LEFEEIEEPE FIALCQKLKV 

        70         80         90        100        110        120 
PDHVRERAWL TWEKVSSVDG ILEGYIQKKK ELWGICIFIA AVDLDEMPFT FTELQKSIET 

       130        140        150        160        170        180 
SVYKFFDLLK EIDTSTKVDN AMSRLLKKYN VLCALYSKLE RTCELIYLTQ PSSALSTEIN 

       190        200        210        220        230        240 
SMLVLKISWI TFLLAKGEVL QMEDDLVISF QLMLCVVDYF IKFSPPALLR EPYKTAALPI 

       250        260        270        280        290        300 
NGSPRTPRRG QNRSARIAKQ LENDTRIIEV LCKEHECNID EVKNVYFKNF IPFINSLGIV 

       310        320        330        340        350        360 
SSNGLPEVES LSKRYEEVYL KNKDLDARLF LDHDKTLQTD PIDSFETERT PRKNNPDEEA 

       370        380        390        400 
NVVTPHTPVR TVMNTIQQLM VILNSASDQP SENLISYFNN CTVNP 

« Hide

References

[1]"High-efficiency full-length cDNA cloning."
Carninci P., Hayashizaki Y.
Methods Enzymol. 303:19-44(1999) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE.
Strain: C57BL/6J EMBL BAB27493.3.
Tissue: Whole body EMBL BAB27493.3.
[2]"Normalization and subtraction of cap-trapper-selected cDNAs to prepare full-length cDNA libraries for rapid discovery of new genes."
Carninci P., Shibata Y., Hayatsu N., Sugahara Y., Shibata K., Itoh M., Konno H., Okazaki Y., Muramatsu M., Hayashizaki Y.
Genome Res. 10:1617-1630(2000) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE.
Strain: C57BL/6J EMBL BAB27493.3.
Tissue: Whole body EMBL BAB27493.3.
[3]"RIKEN integrated sequence analysis (RISA) system--384-format sequencing pipeline with 384 multicapillary sequencer."
Shibata K., Itoh M., Aizawa K., Nagaoka S., Sasaki N., Carninci P., Konno H., Akiyama J., Nishi K., Kitsunai T., Tashiro H., Itoh M., Sumi N., Ishii Y., Nakamura S., Hazama M., Nishine T., Harada A. expand/collapse author list , Yamamoto R., Matsumoto H., Sakaguchi S., Ikegami T., Kashiwagi K., Fujiwake S., Inoue K., Togawa Y., Izawa M., Ohara E., Watahiki M., Yoneda Y., Ishikawa T., Ozawa K., Tanaka T., Matsuura S., Kawai J., Okazaki Y., Muramatsu M., Inoue Y., Kira A., Hayashizaki Y.
Genome Res. 10:1757-1771(2000) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE.
Strain: C57BL/6J EMBL BAB27493.3.
Tissue: Whole body EMBL BAB27493.3.
[4]Adachi J., Aizawa K., Akahira S., Akimura T., Arai A., Aono H., Arakawa T., Bono H., Carninci P., Fukuda S., Fukunishi Y., Furuno M., Hanagaki T., Hara A., Hayatsu N., Hiramoto K., Hiraoka T., Hori F. expand/collapse author list , Imotani K., Ishii Y., Itoh M., Izawa M., Kasukawa T., Kato H., Kawai J., Kojima Y., Konno H., Kouda M., Koya S., Kurihara C., Matsuyama T., Miyazaki A., Nishi K., Nomura K., Numazaki R., Ohno M., Okazaki Y., Okido T., Owa C., Saito H., Saito R., Sakai C., Sakai K., Sano H., Sasaki D., Shibata K., Shibata Y., Shinagawa A., Shiraki T., Sogabe Y., Suzuki H., Tagami M., Tagawa A., Takahashi F., Tanaka T., Tejima Y., Toya T., Yamamura T., Yasunishi A., Yoshida K., Yoshino M., Muramatsu M., Hayashizaki Y.
Submitted (JUL-2000) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE.
Strain: C57BL/6J EMBL BAB27493.3.
Tissue: Whole body EMBL BAB27493.3.
[5]"Functional annotation of a full-length mouse cDNA collection."
The RIKEN Genome Exploration Research Group Phase II Team and the FANTOM Consortium
Nature 409:685-690(2001)
Cited for: NUCLEOTIDE SEQUENCE.
Strain: C57BL/6J EMBL BAB27493.3.
Tissue: Whole body EMBL BAB27493.3.
[6]"Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs."
The FANTOM Consortium and the RIKEN Genome Exploration Research Group Phase I and II Team
Nature 420:563-573(2002)
Cited for: NUCLEOTIDE SEQUENCE.
Strain: C57BL/6J EMBL BAB27493.3.
Tissue: Whole body EMBL BAB27493.3.
[7]"The Transcriptional Landscape of the Mammalian Genome."
The FANTOM Consortium, Riken Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group)
Science 309:1559-1563(2005)
Cited for: NUCLEOTIDE SEQUENCE.
Strain: C57BL/6J EMBL BAB27493.3.
Tissue: Whole body EMBL BAB27493.3.
[8]"Antisense Transcription in the Mammalian Transcriptome."
RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group) and the FANTOM Consortium
Science 309:1564-1566(2005) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE.
Strain: C57BL/6J EMBL BAB27493.3.
Tissue: Whole body EMBL BAB27493.3.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AK011246 mRNA. Translation: BAB27493.3.
UniGeneMm.273862.

3D structure databases

ProteinModelPortalQ9CT40.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING10090.ENSMUSP00000022701.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Organism-specific databases

MGIMGI:97874. Rb1.

Phylogenomic databases

InParanoidQ9CT40.

Gene expression databases

GenevestigatorQ9CT40.

Family and domain databases

InterProIPR015652. RB1.
IPR002720. RB_A.
IPR028309. RB_fam.
IPR024599. RB_N.
[Graphical view]
PANTHERPTHR13742. PTHR13742. 1 hit.
PTHR13742:SF11. PTHR13742:SF11. 1 hit.
PfamPF11934. DUF3452. 1 hit.
PF01858. RB_A. 1 hit.
[Graphical view]
ProtoNetSearch...

Other

SOURCESearch...

Entry information

Entry nameQ9CT40_MOUSE
AccessionPrimary (citable) accession number: Q9CT40
Entry history
Integrated into UniProtKB/TrEMBL: June 1, 2001
Last sequence update: October 11, 2005
Last modified: April 16, 2014
This is version 75 of the entry and version 3 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)