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Protein
Submitted name:

Putative uncharacterized protein

Gene

Upf3b

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

  1. mRNA binding Source: MGI
  2. nucleotide binding Source: InterPro
  3. poly(A) RNA binding Source: MGI

GO - Biological processi

  1. nuclear-transcribed mRNA catabolic process, nonsense-mediated decay Source: MGI
  2. positive regulation of translation Source: MGI
  3. response to unfolded protein Source: MGI
Complete GO annotation...

Enzyme and pathway databases

ReactomeiREACT_198528. Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC).
REACT_232353. Transport of Mature mRNA derived from an Intron-Containing Transcript.
REACT_240247. mRNA 3'-end processing.
REACT_260226. mRNA Splicing - Major Pathway.

Names & Taxonomyi

Protein namesi
Submitted name:
Putative uncharacterized proteinImported
Gene namesi
Name:Upf3bImported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus

Organism-specific databases

MGIiMGI:1915384. Upf3b.

Subcellular locationi

GO - Cellular componenti

  1. cytoplasm Source: MGI
  2. exon-exon junction complex Source: MGI
  3. nucleus Source: MGI
Complete GO annotation...

Expressioni

Gene expression databases

GenevestigatoriQ9CS15.

Structurei

3D structure databases

ProteinModelPortaliQ9CS15.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Phylogenomic databases

HOVERGENiHBG059714.

Family and domain databases

Gene3Di3.30.70.330. 1 hit.
InterProiIPR005120. Nonsense_mediated_decay_UPF3.
IPR012677. Nucleotide-bd_a/b_plait.
[Graphical view]
PfamiPF03467. Smg4_UPF3. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Fragment.

Q9CS15-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MKEEKDHRPK EKRVTLFTPQ GATGGCIGAT AEGAKGDDRQ DRNRDKKEAL
60 70 80 90 100
SKVVIRRLPP TLTKEQLQEH LQPMPEHDYF EFFSNDTSLY PHMYARAYIN
110 120 130 140 150
FKNQEDILLF RDRFDGYVFL DNKGQEYHAI VEFAPFQKAA KKKIKKRDTK
160 170 180 190 200
VGTIEDDPEY RKFLESYATD NEKMTSTPET LLEEIEAKNR ELIAKRTTPL
210 220 230
LSFLKNKQRM REEKREERRR REIERKRQRE EE
Length:232
Mass (Da):27,675
Last modified:June 1, 2001 - v1
Checksum:i5DF971342EB5120B
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei232 – 2321Imported

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK019989 mRNA. Translation: BAB31954.1.
AK162222 mRNA. Translation: BAE36799.1.
UniGeneiMm.271160.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK019989 mRNA. Translation: BAB31954.1.
AK162222 mRNA. Translation: BAE36799.1.
UniGeneiMm.271160.

3D structure databases

ProteinModelPortaliQ9CS15.
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Organism-specific databases

MGIiMGI:1915384. Upf3b.

Phylogenomic databases

HOVERGENiHBG059714.

Enzyme and pathway databases

ReactomeiREACT_198528. Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC).
REACT_232353. Transport of Mature mRNA derived from an Intron-Containing Transcript.
REACT_240247. mRNA 3'-end processing.
REACT_260226. mRNA Splicing - Major Pathway.

Miscellaneous databases

SOURCEiSearch...

Gene expression databases

GenevestigatoriQ9CS15.

Family and domain databases

Gene3Di3.30.70.330. 1 hit.
InterProiIPR005120. Nonsense_mediated_decay_UPF3.
IPR012677. Nucleotide-bd_a/b_plait.
[Graphical view]
PfamiPF03467. Smg4_UPF3. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "High-efficiency full-length cDNA cloning."
    Carninci P., Hayashizaki Y.
    Methods Enzymol. 303:19-44(1999) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
    Tissue: In vitro fertilized eggsImported and Whole bodyImported.
  2. "Normalization and subtraction of cap-trapper-selected cDNAs to prepare full-length cDNA libraries for rapid discovery of new genes."
    Carninci P., Shibata Y., Hayatsu N., Sugahara Y., Shibata K., Itoh M., Konno H., Okazaki Y., Muramatsu M., Hayashizaki Y.
    Genome Res. 10:1617-1630(2000) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
    Tissue: In vitro fertilized eggsImported and Whole bodyImported.
  3. Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
    Tissue: In vitro fertilized eggsImported and Whole bodyImported.
  4. Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
    Tissue: Whole bodyImported.
  5. "Functional annotation of a full-length mouse cDNA collection."
    The RIKEN Genome Exploration Research Group Phase II Team and the FANTOM Consortium
    Nature 409:685-690(2001)
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
    Tissue: In vitro fertilized eggsImported and Whole bodyImported.
  6. "Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs."
    The FANTOM Consortium and the RIKEN Genome Exploration Research Group Phase I and II Team
    Nature 420:563-573(2002)
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
    Tissue: In vitro fertilized eggsImported and Whole bodyImported.
  7. Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
    Tissue: In vitro fertilized eggsImported.
  8. "The Transcriptional Landscape of the Mammalian Genome."
    The FANTOM Consortium, Riken Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group)
    Science 309:1559-1563(2005)
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
    Tissue: In vitro fertilized eggsImported and Whole bodyImported.
  9. Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
    Tissue: In vitro fertilized eggsImported and Whole bodyImported.

Entry informationi

Entry nameiQ9CS15_MOUSE
AccessioniPrimary (citable) accession number: Q9CS15
Entry historyi
Integrated into UniProtKB/TrEMBL: June 1, 2001
Last sequence update: June 1, 2001
Last modified: February 4, 2015
This is version 79 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.