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Q9CRR2

- Q9CRR2_MOUSE

UniProt

Q9CRR2 - Q9CRR2_MOUSE

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Protein
Submitted name:

Putative uncharacterized protein

Gene

Adrb1

Organism
Mus musculus (Mouse)
Status
Unreviewed - Annotation score: 4 out of 5- Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

  1. beta1-adrenergic receptor activity Source: MGI

GO - Biological processi

  1. adenylate cyclase-activating G-protein coupled receptor signaling pathway Source: MGI
  2. adrenergic receptor signaling pathway Source: GOC
  3. brown fat cell differentiation Source: MGI
  4. diet induced thermogenesis Source: MGI
  5. fear response Source: MGI
  6. heat generation Source: MGI
  7. negative regulation of multicellular organism growth Source: MGI
  8. positive regulation of heart rate by epinephrine-norepinephrine Source: MGI
  9. positive regulation of the force of heart contraction by epinephrine-norepinephrine Source: MGI
  10. response to cold Source: MGI
  11. vasodilation by norepinephrine-epinephrine involved in regulation of systemic arterial blood pressure Source: MGI
Complete GO annotation...

Keywords - Molecular functioni

G-protein coupled receptorUniRule annotationSAAS annotation, Receptor, Transducer

Names & Taxonomyi

Protein namesi
Submitted name:
Putative uncharacterized proteinImported
Gene namesi
Name:Adrb1Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus

Organism-specific databases

MGIiMGI:87937. Adrb1.

Subcellular locationi

GO - Cellular componenti

  1. integral component of membrane Source: UniProtKB-KW
  2. membrane Source: MGI
  3. plasma membrane Source: UniProtKB-KW
Complete GO annotation...

Keywords - Cellular componenti

Cell membraneSAAS annotation, Membrane

Expressioni

Gene expression databases

GenevestigatoriQ9CRR2.

Structurei

3D structure databases

ProteinModelPortaliQ9CRR2.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the G-protein coupled receptor 1 family.UniRule annotation

Keywords - Domaini

Transmembrane, Transmembrane helixSAAS annotation

Phylogenomic databases

HOVERGENiHBG106962.

Family and domain databases

Gene3Di1.20.1070.10. 1 hit.
InterProiIPR002233. ADR_fam.
IPR000507. ADRB1_rcpt.
IPR000276. GPCR_Rhodpsn.
IPR017452. GPCR_Rhodpsn_7TM.
[Graphical view]
PfamiPF00001. 7tm_1. 1 hit.
[Graphical view]
PRINTSiPR01103. ADRENERGICR.
PR00561. ADRENRGCB1AR.
PR00237. GPCRRHODOPSN.
PROSITEiPS00237. G_PROTEIN_RECEP_F1_1. 1 hit.
PS50262. G_PROTEIN_RECEP_F1_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Fragment.

Q9CRR2-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
GLQLALIVLL IVVGNVLVIV AIAKTPRLQT LTNLFIMSLA SADLVMGLLV
60 70 80 90 100
VPFGATIVVW GRWEYGSFFC ELWTSVDVLC VTASIETLCV IALDRYLAIT
110 120 130 140 150
SPFRYQSLLT RARARALVCT VWAISALVSF LPILMHWWRA ESDEARRCYN
160 170 180 190 200
DPKCCDFVTN RAYAIASSVV SFYVPLCIMA FVYLRVFREA QKQVKKIDSC
210 220 230 240 250
ERRFLGGPAR PPSPEPSPSP GPPRPADSLA NGRSSKRRPS RLVALREQKA
260 270 280 290 300
LKTLGIIMGV FTLCWLPFFL ANVVKAFHRD LVPDRLFVFF NWLGYANSAF
310 320 330 340 350
NPIIYCRSPD FRKAFQRLLC CARRAACRRR AAHGDRPRAS GCLARAGPPP
360 370 380 390 400
SPGAPSDDDD DDAGTTPPAR LLEPWTGCNG GTTTVDSDSS LDEPGRQGFS

SESKV
Length:405
Mass (Da):44,742
Last modified:June 1, 2001 - v1
Checksum:i4F0F3FBB956EF2F4
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei1 – 11Imported

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK018378 mRNA. Translation: BAB31185.1.
UniGeneiMm.46797.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK018378 mRNA. Translation: BAB31185.1 .
UniGenei Mm.46797.

3D structure databases

ProteinModelPortali Q9CRR2.
ModBasei Search...
MobiDBi Search...

Protein family/group databases

GPCRDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Organism-specific databases

MGIi MGI:87937. Adrb1.

Phylogenomic databases

HOVERGENi HBG106962.

Miscellaneous databases

SOURCEi Search...

Gene expression databases

Genevestigatori Q9CRR2.

Family and domain databases

Gene3Di 1.20.1070.10. 1 hit.
InterProi IPR002233. ADR_fam.
IPR000507. ADRB1_rcpt.
IPR000276. GPCR_Rhodpsn.
IPR017452. GPCR_Rhodpsn_7TM.
[Graphical view ]
Pfami PF00001. 7tm_1. 1 hit.
[Graphical view ]
PRINTSi PR01103. ADRENERGICR.
PR00561. ADRENRGCB1AR.
PR00237. GPCRRHODOPSN.
PROSITEi PS00237. G_PROTEIN_RECEP_F1_1. 1 hit.
PS50262. G_PROTEIN_RECEP_F1_2. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "High-efficiency full-length cDNA cloning."
    Carninci P., Hayashizaki Y.
    Methods Enzymol. 303:19-44(1999) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
    Tissue: LungImported.
  2. "Normalization and subtraction of cap-trapper-selected cDNAs to prepare full-length cDNA libraries for rapid discovery of new genes."
    Carninci P., Shibata Y., Hayatsu N., Sugahara Y., Shibata K., Itoh M., Konno H., Okazaki Y., Muramatsu M., Hayashizaki Y.
    Genome Res. 10:1617-1630(2000) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
    Tissue: LungImported.
  3. Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
    Tissue: LungImported.
  4. Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
    Tissue: LungImported.
  5. "Functional annotation of a full-length mouse cDNA collection."
    The RIKEN Genome Exploration Research Group Phase II Team and the FANTOM Consortium
    Nature 409:685-690(2001)
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
    Tissue: LungImported.
  6. "Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs."
    The FANTOM Consortium and the RIKEN Genome Exploration Research Group Phase I and II Team
    Nature 420:563-573(2002)
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
    Tissue: LungImported.
  7. "The Transcriptional Landscape of the Mammalian Genome."
    The FANTOM Consortium, Riken Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group)
    Science 309:1559-1563(2005)
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
    Tissue: LungImported.
  8. Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
    Tissue: LungImported.

Entry informationi

Entry nameiQ9CRR2_MOUSE
AccessioniPrimary (citable) accession number: Q9CRR2
Entry historyi
Integrated into UniProtKB/TrEMBL: June 1, 2001
Last sequence update: June 1, 2001
Last modified: October 29, 2014
This is version 86 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)