UniProtKB - Q9CR99 (Q9CR99_MOUSE)
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Protein
Submitted name:
Putative uncharacterized protein
Gene
4930544G11Rik
Organism
Mus musculus (Mouse)
Status
Functioni
GO - Molecular functioni
- GTPase activity Source: InterPro
- GTP binding Source: UniProtKB-KW
GO - Biological processi
- small GTPase mediated signal transduction Source: InterPro
Keywordsi
| Ligand | GTP-bindingSAAS annotation, Nucleotide-binding |
Enzyme and pathway databases
| Reactomei | R-MMU-114604. GPVI-mediated activation cascade. R-MMU-193634. Axonal growth inhibition (RHOA activation). R-MMU-194840. Rho GTPase cycle. R-MMU-198203. PI3K/AKT activation. R-MMU-209563. Axonal growth stimulation. R-MMU-2173791. TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition). R-MMU-392451. G beta:gamma signalling through PI3Kgamma. R-MMU-3928662. EPHB-mediated forward signaling. R-MMU-3928663. EPHA-mediated growth cone collapse. R-MMU-4086400. PCP/CE pathway. R-MMU-416482. G alpha (12/13) signalling events. R-MMU-416550. Sema4D mediated inhibition of cell attachment and migration. R-MMU-416572. Sema4D induced cell migration and growth-cone collapse. R-MMU-4420097. VEGFA-VEGFR2 Pathway. R-MMU-5625740. RHO GTPases activate PKNs. R-MMU-5625900. RHO GTPases activate CIT. R-MMU-5625970. RHO GTPases activate KTN1. R-MMU-5627117. RHO GTPases Activate ROCKs. R-MMU-5663220. RHO GTPases Activate Formins. R-MMU-5666185. RHO GTPases Activate Rhotekin and Rhophilins. R-MMU-5689896. Ovarian tumor domain proteases. R-MMU-6785631. ERBB2 Regulates Cell Motility. R-MMU-6798695. Neutrophil degranulation. R-MMU-8849471. PTK6 Regulates RHO GTPases, RAS GTPase and MAP kinases. |
Names & Taxonomyi
| Protein namesi | Submitted name: Putative uncharacterized proteinImportedSubmitted name: RIKEN cDNA 4930544G11ImportedSubmitted name: RIKEN cDNA 4930544G11 geneImported |
| Gene namesi | Name:4930544G11RikImported ORF Names:mCG_125315Imported |
| Organismi | Mus musculus (Mouse) |
| Taxonomic identifieri | 10090 [NCBI] |
| Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Glires › Rodentia › Myomorpha › Muroidea › Muridae › Murinae › Mus › Mus |
| Proteomesi |
|
Organism-specific databases
| MGIi | MGI:1914903. 4930544G11Rik. |
Subcellular locationi
GO - Cellular componenti
- intracellular Source: InterPro
- membrane Source: UniProtKB-KW
Keywords - Cellular componenti
MembraneSAAS annotationFamily & Domainsi
Sequence similaritiesi
Phylogenomic databases
| eggNOGi | KOG0393. Eukaryota. COG1100. LUCA. |
| GeneTreei | ENSGT00760000119020. |
| HOVERGENi | HBG009351. |
| KOi | K04513. |
| OMAi | TRINAFY. |
| OrthoDBi | EOG091G0QVS. |
| TreeFami | TF300837. |
Family and domain databases
| InterProi | View protein in InterPro IPR027417. P-loop_NTPase. IPR005225. Small_GTP-bd_dom. IPR001806. Small_GTPase. IPR003578. Small_GTPase_Rho. |
| Pfami | View protein in Pfam PF00071. Ras. 1 hit. |
| SUPFAMi | SSF52540. SSF52540. 1 hit. |
| TIGRFAMsi | TIGR00231. small_GTP. 1 hit. |
| PROSITEi | View protein in PROSITE PS51420. RHO. 1 hit. |
Sequencei
Sequence statusi: Complete.
Q9CR99-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MAAIRKKLVI VGDGACGKTC LLIVFSKDQF PEVYVPTVFE NYVADIEVDG
60 70 80 90 100
KQVELALWDT AGQEDYDRLR PLSYPDTDVL LLCFSIGNPD SFGNIPHKWI
110 120 130 140 150
PEVKHFCPNV PIILVGSKKD LRNDFYTIQE LAKRKQAPVR PEQGQGLANS
160 170 180 190
IGAFEYVECS AKTKDGVRRV FEKATRAALQ TNRVKKKTGC FVF
Sequence databases
| Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AC154005 Genomic DNA. No translation available. AK006363 mRNA. Translation: BAB24547.1. AK016035 mRNA. Translation: BAB30087.1. CH466523 Genomic DNA. Translation: EDK98782.1. |
| RefSeqi | NP_001155245.1. NM_001161773.1. |
| UniGenei | Mm.389756. |
Genome annotation databases
| Ensembli | ENSMUST00000043382; ENSMUSP00000045487; ENSMUSG00000036463. |
| GeneIDi | 67653. |
| KEGGi | mmu:67653. |
| UCSCi | uc009cem.2. mouse. |
Similar proteinsi
Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:| 100% | UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry. |
| 90% | UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence). |
| 50% | UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster. |
Entry informationi
| Entry namei | Q9CR99_MOUSE | |
| Accessioni | Q9CR99Primary (citable) accession number: Q9CR99 | |
| Entry historyi | Integrated into UniProtKB/TrEMBL: | June 1, 2001 |
| Last sequence update: | June 1, 2001 | |
| Last modified: | July 5, 2017 | |
| This is version 135 of the entry and version 1 of the sequence. See complete history. | ||
| Entry statusi | Unreviewed (UniProtKB/TrEMBL) | |
