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Protein
Submitted name:

Putative uncharacterized protein

Gene

4930544G11Rik

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

LigandGTP-bindingSAAS annotation, Nucleotide-binding

Enzyme and pathway databases

ReactomeiR-MMU-114604. GPVI-mediated activation cascade.
R-MMU-193634. Axonal growth inhibition (RHOA activation).
R-MMU-194840. Rho GTPase cycle.
R-MMU-198203. PI3K/AKT activation.
R-MMU-209563. Axonal growth stimulation.
R-MMU-2173791. TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition).
R-MMU-392451. G beta:gamma signalling through PI3Kgamma.
R-MMU-3928662. EPHB-mediated forward signaling.
R-MMU-3928663. EPHA-mediated growth cone collapse.
R-MMU-4086400. PCP/CE pathway.
R-MMU-416482. G alpha (12/13) signalling events.
R-MMU-416550. Sema4D mediated inhibition of cell attachment and migration.
R-MMU-416572. Sema4D induced cell migration and growth-cone collapse.
R-MMU-4420097. VEGFA-VEGFR2 Pathway.
R-MMU-5625740. RHO GTPases activate PKNs.
R-MMU-5625900. RHO GTPases activate CIT.
R-MMU-5625970. RHO GTPases activate KTN1.
R-MMU-5627117. RHO GTPases Activate ROCKs.
R-MMU-5663220. RHO GTPases Activate Formins.
R-MMU-5666185. RHO GTPases Activate Rhotekin and Rhophilins.
R-MMU-5689896. Ovarian tumor domain proteases.
R-MMU-6785631. ERBB2 Regulates Cell Motility.
R-MMU-6798695. Neutrophil degranulation.
R-MMU-8849471. PTK6 Regulates RHO GTPases, RAS GTPase and MAP kinases.

Names & Taxonomyi

Protein namesi
Submitted name:
Putative uncharacterized proteinImported
Submitted name:
RIKEN cDNA 4930544G11Imported
Submitted name:
RIKEN cDNA 4930544G11 geneImported
Gene namesi
Name:4930544G11RikImported
ORF Names:mCG_125315Imported
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 6

Organism-specific databases

MGIiMGI:1914903. 4930544G11Rik.

Subcellular locationi

GO - Cellular componenti

Keywords - Cellular componenti

MembraneSAAS annotation

Expressioni

Gene expression databases

BgeeiENSMUSG00000036463.

Interactioni

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000045487.

Family & Domainsi

Sequence similaritiesi

Belongs to the small GTPase superfamily. Rho family.SAAS annotation

Phylogenomic databases

eggNOGiKOG0393. Eukaryota.
COG1100. LUCA.
GeneTreeiENSGT00760000119020.
HOVERGENiHBG009351.
KOiK04513.
OMAiTRINAFY.
OrthoDBiEOG091G0QVS.
TreeFamiTF300837.

Family and domain databases

InterProiView protein in InterPro
IPR027417. P-loop_NTPase.
IPR005225. Small_GTP-bd_dom.
IPR001806. Small_GTPase.
IPR003578. Small_GTPase_Rho.
PfamiView protein in Pfam
PF00071. Ras. 1 hit.
SUPFAMiSSF52540. SSF52540. 1 hit.
TIGRFAMsiTIGR00231. small_GTP. 1 hit.
PROSITEiView protein in PROSITE
PS51420. RHO. 1 hit.

Sequencei

Sequence statusi: Complete.

Q9CR99-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAAIRKKLVI VGDGACGKTC LLIVFSKDQF PEVYVPTVFE NYVADIEVDG
60 70 80 90 100
KQVELALWDT AGQEDYDRLR PLSYPDTDVL LLCFSIGNPD SFGNIPHKWI
110 120 130 140 150
PEVKHFCPNV PIILVGSKKD LRNDFYTIQE LAKRKQAPVR PEQGQGLANS
160 170 180 190
IGAFEYVECS AKTKDGVRRV FEKATRAALQ TNRVKKKTGC FVF
Length:193
Mass (Da):21,644
Last modified:June 1, 2001 - v1
Checksum:i0C00187165B08E10
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC154005 Genomic DNA. No translation available.
AK006363 mRNA. Translation: BAB24547.1.
AK016035 mRNA. Translation: BAB30087.1.
CH466523 Genomic DNA. Translation: EDK98782.1.
RefSeqiNP_001155245.1. NM_001161773.1.
UniGeneiMm.389756.

Genome annotation databases

EnsembliENSMUST00000043382; ENSMUSP00000045487; ENSMUSG00000036463.
GeneIDi67653.
KEGGimmu:67653.
UCSCiuc009cem.2. mouse.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.

Entry informationi

Entry nameiQ9CR99_MOUSE
AccessioniPrimary (citable) accession number: Q9CR99
Entry historyiIntegrated into UniProtKB/TrEMBL: June 1, 2001
Last sequence update: June 1, 2001
Last modified: July 5, 2017
This is version 135 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported