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Protein

Immediate early response 3-interacting protein 1

Gene

Ier3ip1

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

May be implicated in the regulation of apoptosis. May be involved in protein transport between endoplasmic reticulum and Golgi apparatus.By similarity

GO - Biological processi

Complete GO annotation...

Names & Taxonomyi

Protein namesi
Recommended name:
Immediate early response 3-interacting protein 1
Gene namesi
Name:Ier3ip1Imported
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 18

Organism-specific databases

MGIiMGI:1913441. Ier3ip1.

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei2 – 2221HelicalSequence analysisAdd
BLAST
Transmembranei62 – 8221HelicalSequence analysisAdd
BLAST

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Endoplasmic reticulum, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 8282Immediate early response 3-interacting protein 1PRO_0000257962Add
BLAST

Proteomic databases

EPDiQ9CR20.
MaxQBiQ9CR20.
PaxDbiQ9CR20.
PRIDEiQ9CR20.

PTM databases

PhosphoSiteiQ9CR20.

Expressioni

Gene expression databases

BgeeiQ9CR20.
CleanExiMM_IER3IP1.
GenevisibleiQ9CR20. MM.

Interactioni

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000026487.

Structurei

3D structure databases

ProteinModelPortaliQ9CR20.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the YOS1 family.Sequence analysis

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiKOG4779. Eukaryota.
ENOG4111WBM. LUCA.
GeneTreeiENSGT00510000047648.
HOGENOMiHOG000192480.
HOVERGENiHBG081806.
InParanoidiQ9CR20.
OMAiAVNSVCI.
OrthoDBiEOG7P2XT1.
PhylomeDBiQ9CR20.
TreeFamiTF300263.

Family and domain databases

InterProiIPR013880. Yos1.
[Graphical view]
PANTHERiPTHR15858. PTHR15858. 1 hit.
PfamiPF08571. Yos1. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q9CR20-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAFTLYSLMQ AALLCVNAIA VLHEERFLKN IGWGTDQGIG GFGEEPGIKS
60 70 80
QLMNLIRSVR TVMRVPLIIV NSITIVLLLL FG
Length:82
Mass (Da):9,017
Last modified:June 1, 2001 - v1
Checksum:i3015F654F1EBB080
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK004281 mRNA. Translation: BAB23248.1.
AK007388 mRNA. Translation: BAB25005.1.
AK007862 mRNA. Translation: BAB25314.1.
AK009116 mRNA. Translation: BAB26081.1.
BC021512 mRNA. Translation: AAH21512.1.
CCDSiCCDS37862.1.
RefSeqiNP_079685.1. NM_025409.3.
UniGeneiMm.28593.

Genome annotation databases

EnsembliENSMUST00000026487; ENSMUSP00000026487; ENSMUSG00000090000.
GeneIDi66191.
KEGGimmu:66191.
UCSCiuc008fqr.2. mouse.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK004281 mRNA. Translation: BAB23248.1.
AK007388 mRNA. Translation: BAB25005.1.
AK007862 mRNA. Translation: BAB25314.1.
AK009116 mRNA. Translation: BAB26081.1.
BC021512 mRNA. Translation: AAH21512.1.
CCDSiCCDS37862.1.
RefSeqiNP_079685.1. NM_025409.3.
UniGeneiMm.28593.

3D structure databases

ProteinModelPortaliQ9CR20.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000026487.

PTM databases

PhosphoSiteiQ9CR20.

Proteomic databases

EPDiQ9CR20.
MaxQBiQ9CR20.
PaxDbiQ9CR20.
PRIDEiQ9CR20.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000026487; ENSMUSP00000026487; ENSMUSG00000090000.
GeneIDi66191.
KEGGimmu:66191.
UCSCiuc008fqr.2. mouse.

Organism-specific databases

CTDi51124.
MGIiMGI:1913441. Ier3ip1.

Phylogenomic databases

eggNOGiKOG4779. Eukaryota.
ENOG4111WBM. LUCA.
GeneTreeiENSGT00510000047648.
HOGENOMiHOG000192480.
HOVERGENiHBG081806.
InParanoidiQ9CR20.
OMAiAVNSVCI.
OrthoDBiEOG7P2XT1.
PhylomeDBiQ9CR20.
TreeFamiTF300263.

Miscellaneous databases

PROiQ9CR20.
SOURCEiSearch...

Gene expression databases

BgeeiQ9CR20.
CleanExiMM_IER3IP1.
GenevisibleiQ9CR20. MM.

Family and domain databases

InterProiIPR013880. Yos1.
[Graphical view]
PANTHERiPTHR15858. PTHR15858. 1 hit.
PfamiPF08571. Yos1. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "The transcriptional landscape of the mammalian genome."
    Carninci P., Kasukawa T., Katayama S., Gough J., Frith M.C., Maeda N., Oyama R., Ravasi T., Lenhard B., Wells C., Kodzius R., Shimokawa K., Bajic V.B., Brenner S.E., Batalov S., Forrest A.R., Zavolan M., Davis M.J.
    , Wilming L.G., Aidinis V., Allen J.E., Ambesi-Impiombato A., Apweiler R., Aturaliya R.N., Bailey T.L., Bansal M., Baxter L., Beisel K.W., Bersano T., Bono H., Chalk A.M., Chiu K.P., Choudhary V., Christoffels A., Clutterbuck D.R., Crowe M.L., Dalla E., Dalrymple B.P., de Bono B., Della Gatta G., di Bernardo D., Down T., Engstrom P., Fagiolini M., Faulkner G., Fletcher C.F., Fukushima T., Furuno M., Futaki S., Gariboldi M., Georgii-Hemming P., Gingeras T.R., Gojobori T., Green R.E., Gustincich S., Harbers M., Hayashi Y., Hensch T.K., Hirokawa N., Hill D., Huminiecki L., Iacono M., Ikeo K., Iwama A., Ishikawa T., Jakt M., Kanapin A., Katoh M., Kawasawa Y., Kelso J., Kitamura H., Kitano H., Kollias G., Krishnan S.P., Kruger A., Kummerfeld S.K., Kurochkin I.V., Lareau L.F., Lazarevic D., Lipovich L., Liu J., Liuni S., McWilliam S., Madan Babu M., Madera M., Marchionni L., Matsuda H., Matsuzawa S., Miki H., Mignone F., Miyake S., Morris K., Mottagui-Tabar S., Mulder N., Nakano N., Nakauchi H., Ng P., Nilsson R., Nishiguchi S., Nishikawa S., Nori F., Ohara O., Okazaki Y., Orlando V., Pang K.C., Pavan W.J., Pavesi G., Pesole G., Petrovsky N., Piazza S., Reed J., Reid J.F., Ring B.Z., Ringwald M., Rost B., Ruan Y., Salzberg S.L., Sandelin A., Schneider C., Schoenbach C., Sekiguchi K., Semple C.A., Seno S., Sessa L., Sheng Y., Shibata Y., Shimada H., Shimada K., Silva D., Sinclair B., Sperling S., Stupka E., Sugiura K., Sultana R., Takenaka Y., Taki K., Tammoja K., Tan S.L., Tang S., Taylor M.S., Tegner J., Teichmann S.A., Ueda H.R., van Nimwegen E., Verardo R., Wei C.L., Yagi K., Yamanishi H., Zabarovsky E., Zhu S., Zimmer A., Hide W., Bult C., Grimmond S.M., Teasdale R.D., Liu E.T., Brusic V., Quackenbush J., Wahlestedt C., Mattick J.S., Hume D.A., Kai C., Sasaki D., Tomaru Y., Fukuda S., Kanamori-Katayama M., Suzuki M., Aoki J., Arakawa T., Iida J., Imamura K., Itoh M., Kato T., Kawaji H., Kawagashira N., Kawashima T., Kojima M., Kondo S., Konno H., Nakano K., Ninomiya N., Nishio T., Okada M., Plessy C., Shibata K., Shiraki T., Suzuki S., Tagami M., Waki K., Watahiki A., Okamura-Oho Y., Suzuki H., Kawai J., Hayashizaki Y.
    Science 309:1559-1563(2005) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Strain: C57BL/6JImported.
    Tissue: EmbryoImported, PancreasImported and TongueImported.
  2. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Strain: FVB/NImported.
    Tissue: Mammary glandImported.

Entry informationi

Entry nameiIR3IP_MOUSE
AccessioniPrimary (citable) accession number: Q9CR20
Entry historyi
Integrated into UniProtKB/Swiss-Prot: October 31, 2006
Last sequence update: June 1, 2001
Last modified: June 8, 2016
This is version 89 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.