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Protein

Immediate early response 3-interacting protein 1

Gene

Ier3ip1

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

May be implicated in the regulation of apoptosis. May be involved in protein transport between endoplasmic reticulum and Golgi apparatus.By similarity

GO - Biological processi

Complete GO annotation...

Names & Taxonomyi

Protein namesi
Recommended name:
Immediate early response 3-interacting protein 1
Gene namesi
Name:Ier3ip1Imported
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 18

Organism-specific databases

MGIiMGI:1913441. Ier3ip1.

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei2 – 22HelicalSequence analysisAdd BLAST21
Transmembranei62 – 82HelicalSequence analysisAdd BLAST21

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Endoplasmic reticulum, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002579621 – 82Immediate early response 3-interacting protein 1Add BLAST82

Proteomic databases

EPDiQ9CR20.
MaxQBiQ9CR20.
PaxDbiQ9CR20.
PRIDEiQ9CR20.

PTM databases

PhosphoSitePlusiQ9CR20.

Expressioni

Gene expression databases

BgeeiENSMUSG00000090000.
CleanExiMM_IER3IP1.
GenevisibleiQ9CR20. MM.

Interactioni

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000026487.

Structurei

3D structure databases

ProteinModelPortaliQ9CR20.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the YOS1 family.Sequence analysis

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiKOG4779. Eukaryota.
ENOG4111WBM. LUCA.
GeneTreeiENSGT00510000047648.
HOGENOMiHOG000192480.
HOVERGENiHBG081806.
InParanoidiQ9CR20.
OMAiAVNSVCI.
OrthoDBiEOG091G191B.
PhylomeDBiQ9CR20.
TreeFamiTF300263.

Family and domain databases

InterProiIPR013880. Yos1.
[Graphical view]
PANTHERiPTHR15858. PTHR15858. 1 hit.
PfamiPF08571. Yos1. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q9CR20-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAFTLYSLMQ AALLCVNAIA VLHEERFLKN IGWGTDQGIG GFGEEPGIKS
60 70 80
QLMNLIRSVR TVMRVPLIIV NSITIVLLLL FG
Length:82
Mass (Da):9,017
Last modified:June 1, 2001 - v1
Checksum:i3015F654F1EBB080
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK004281 mRNA. Translation: BAB23248.1.
AK007388 mRNA. Translation: BAB25005.1.
AK007862 mRNA. Translation: BAB25314.1.
AK009116 mRNA. Translation: BAB26081.1.
BC021512 mRNA. Translation: AAH21512.1.
CCDSiCCDS37862.1.
RefSeqiNP_079685.1. NM_025409.3.
UniGeneiMm.28593.

Genome annotation databases

EnsembliENSMUST00000026487; ENSMUSP00000026487; ENSMUSG00000090000.
GeneIDi66191.
KEGGimmu:66191.
UCSCiuc008fqr.2. mouse.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK004281 mRNA. Translation: BAB23248.1.
AK007388 mRNA. Translation: BAB25005.1.
AK007862 mRNA. Translation: BAB25314.1.
AK009116 mRNA. Translation: BAB26081.1.
BC021512 mRNA. Translation: AAH21512.1.
CCDSiCCDS37862.1.
RefSeqiNP_079685.1. NM_025409.3.
UniGeneiMm.28593.

3D structure databases

ProteinModelPortaliQ9CR20.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000026487.

PTM databases

PhosphoSitePlusiQ9CR20.

Proteomic databases

EPDiQ9CR20.
MaxQBiQ9CR20.
PaxDbiQ9CR20.
PRIDEiQ9CR20.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000026487; ENSMUSP00000026487; ENSMUSG00000090000.
GeneIDi66191.
KEGGimmu:66191.
UCSCiuc008fqr.2. mouse.

Organism-specific databases

CTDi51124.
MGIiMGI:1913441. Ier3ip1.

Phylogenomic databases

eggNOGiKOG4779. Eukaryota.
ENOG4111WBM. LUCA.
GeneTreeiENSGT00510000047648.
HOGENOMiHOG000192480.
HOVERGENiHBG081806.
InParanoidiQ9CR20.
OMAiAVNSVCI.
OrthoDBiEOG091G191B.
PhylomeDBiQ9CR20.
TreeFamiTF300263.

Miscellaneous databases

PROiQ9CR20.
SOURCEiSearch...

Gene expression databases

BgeeiENSMUSG00000090000.
CleanExiMM_IER3IP1.
GenevisibleiQ9CR20. MM.

Family and domain databases

InterProiIPR013880. Yos1.
[Graphical view]
PANTHERiPTHR15858. PTHR15858. 1 hit.
PfamiPF08571. Yos1. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiIR3IP_MOUSE
AccessioniPrimary (citable) accession number: Q9CR20
Entry historyi
Integrated into UniProtKB/Swiss-Prot: October 31, 2006
Last sequence update: June 1, 2001
Last modified: November 2, 2016
This is version 92 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.