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Protein

Ubiquitin-fold modifier-conjugating enzyme 1

Gene

Ufc1

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

E2-like enzyme which forms an intermediate with UFM1 via a thioester linkage.By similarity

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei116Glycyl thioester intermediateBy similarity1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Biological processUbl conjugation pathway

Names & Taxonomyi

Protein namesi
Recommended name:
Ubiquitin-fold modifier-conjugating enzyme 1
Short name:
Ufm1-conjugating enzyme 1
Gene namesi
Name:Ufc1
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi

Organism-specific databases

MGIiMGI:1913405 Ufc1

Subcellular locationi

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000826141 – 167Ubiquitin-fold modifier-conjugating enzyme 1Add BLAST167

Proteomic databases

EPDiQ9CR09
MaxQBiQ9CR09
PaxDbiQ9CR09
PeptideAtlasiQ9CR09
PRIDEiQ9CR09

PTM databases

iPTMnetiQ9CR09
PhosphoSitePlusiQ9CR09
SwissPalmiQ9CR09

Expressioni

Gene expression databases

BgeeiENSMUSG00000062963
CleanExiMM_UFC1
ExpressionAtlasiQ9CR09 baseline and differential
GenevisibleiQ9CR09 MM

Interactioni

Subunit structurei

Interacts with UBA5 (via C-terminus). Interacts with UFL1. Interacts with KIRREL3.By similarity

Protein-protein interaction databases

IntActiQ9CR09, 5 interactors
MINTiQ9CR09
STRINGi10090.ENSMUSP00000078914

Structurei

3D structure databases

ProteinModelPortaliQ9CR09
SMRiQ9CR09
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiKOG3357 Eukaryota
ENOG410ZBCX LUCA
GeneTreeiENSGT00390000008196
HOGENOMiHOG000243361
HOVERGENiHBG054254
InParanoidiQ9CR09
KOiK12165
OMAiEHFKPLW
OrthoDBiEOG091G0MP6
PhylomeDBiQ9CR09
TreeFamiTF313587

Family and domain databases

Gene3Di3.10.110.10, 1 hit
InterProiView protein in InterPro
IPR016135 UBQ-conjugating_enzyme/RWD
IPR014806 Ufc1
PANTHERiPTHR12921 PTHR12921, 1 hit
PfamiView protein in Pfam
PF08694 UFC1, 1 hit
PIRSFiPIRSF008716 DUF1782, 1 hit
SUPFAMiSSF54495 SSF54495, 1 hit

Sequencei

Sequence statusi: Complete.

Q9CR09-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MADEATRRVV SEIPVLKTNA GPRDRELWVQ RLKEEYQSLI RYVENNKNSD
60 70 80 90 100
NDWFRLESNK EGTRWFGKCW YIHDFLKYEF DIEFEIPITY PTTAPEIAVP
110 120 130 140 150
ELDGKTAKMY RGGKICLTDH FKPLWARNVP KFGLAHLMAL GLGPWLAVEV
160
PDLIQKGVIQ HKEKCSQ
Length:167
Mass (Da):19,481
Last modified:June 1, 2001 - v1
Checksum:i359C44F2CE1FE3E0
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK003070 mRNA Translation: BAB22546.1
AK003897 mRNA Translation: BAB23063.1
BC021936 mRNA Translation: AAH21936.1
CCDSiCCDS15488.1
RefSeqiNP_079664.1, NM_025388.2
UniGeneiMm.2815

Genome annotation databases

EnsembliENSMUST00000080001; ENSMUSP00000078914; ENSMUSG00000062963
ENSMUST00000111302; ENSMUSP00000106933; ENSMUSG00000062963
GeneIDi66155
KEGGimmu:66155
UCSCiuc007dnw.1 mouse

Similar proteinsi

Entry informationi

Entry nameiUFC1_MOUSE
AccessioniPrimary (citable) accession number: Q9CR09
Entry historyiIntegrated into UniProtKB/Swiss-Prot: April 26, 2005
Last sequence update: June 1, 2001
Last modified: May 23, 2018
This is version 108 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
  2. SIMILARITY comments
    Index of protein domains and families

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