Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Ubiquitin-fold modifier-conjugating enzyme 1

Gene

Ufc1

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

E2-like enzyme which forms an intermediate with UFM1 via a thioester linkage.By similarity

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei116 – 1161Glycyl thioester intermediateBy similarity

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Biological processi

Ubl conjugation pathway

Names & Taxonomyi

Protein namesi
Recommended name:
Ubiquitin-fold modifier-conjugating enzyme 1
Short name:
Ufm1-conjugating enzyme 1
Gene namesi
Name:Ufc1
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 1

Organism-specific databases

MGIiMGI:1913405. Ufc1.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 167167Ubiquitin-fold modifier-conjugating enzyme 1PRO_0000082614Add
BLAST

Proteomic databases

EPDiQ9CR09.
MaxQBiQ9CR09.
PaxDbiQ9CR09.
PeptideAtlasiQ9CR09.
PRIDEiQ9CR09.

PTM databases

iPTMnetiQ9CR09.
PhosphoSiteiQ9CR09.

Expressioni

Gene expression databases

BgeeiENSMUSG00000062963.
CleanExiMM_UFC1.
ExpressionAtlasiQ9CR09. baseline and differential.
GenevisibleiQ9CR09. MM.

Interactioni

Subunit structurei

Interacts with UBA5. Interacts with UFL1. Interacts with KIRREL3.By similarity

Protein-protein interaction databases

IntActiQ9CR09. 5 interactions.
MINTiMINT-217621.
STRINGi10090.ENSMUSP00000078914.

Structurei

3D structure databases

ProteinModelPortaliQ9CR09.
SMRiQ9CR09. Positions 1-163.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiKOG3357. Eukaryota.
ENOG410ZBCX. LUCA.
GeneTreeiENSGT00390000008196.
HOGENOMiHOG000243361.
HOVERGENiHBG054254.
InParanoidiQ9CR09.
KOiK12165.
OMAiEHFKPLW.
OrthoDBiEOG091G0MP6.
PhylomeDBiQ9CR09.
TreeFamiTF313587.

Family and domain databases

InterProiIPR016135. UBQ-conjugating_enzyme/RWD.
IPR014806. Ufc1.
[Graphical view]
PANTHERiPTHR12921. PTHR12921. 1 hit.
PfamiPF08694. UFC1. 1 hit.
[Graphical view]
PIRSFiPIRSF008716. DUF1782. 1 hit.
SUPFAMiSSF54495. SSF54495. 1 hit.

Sequencei

Sequence statusi: Complete.

Q9CR09-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MADEATRRVV SEIPVLKTNA GPRDRELWVQ RLKEEYQSLI RYVENNKNSD
60 70 80 90 100
NDWFRLESNK EGTRWFGKCW YIHDFLKYEF DIEFEIPITY PTTAPEIAVP
110 120 130 140 150
ELDGKTAKMY RGGKICLTDH FKPLWARNVP KFGLAHLMAL GLGPWLAVEV
160
PDLIQKGVIQ HKEKCSQ
Length:167
Mass (Da):19,481
Last modified:June 1, 2001 - v1
Checksum:i359C44F2CE1FE3E0
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK003070 mRNA. Translation: BAB22546.1.
AK003897 mRNA. Translation: BAB23063.1.
BC021936 mRNA. Translation: AAH21936.1.
CCDSiCCDS15488.1.
RefSeqiNP_079664.1. NM_025388.2.
UniGeneiMm.2815.

Genome annotation databases

EnsembliENSMUST00000080001; ENSMUSP00000078914; ENSMUSG00000062963.
ENSMUST00000111302; ENSMUSP00000106933; ENSMUSG00000062963.
GeneIDi66155.
KEGGimmu:66155.
UCSCiuc007dnw.1. mouse.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK003070 mRNA. Translation: BAB22546.1.
AK003897 mRNA. Translation: BAB23063.1.
BC021936 mRNA. Translation: AAH21936.1.
CCDSiCCDS15488.1.
RefSeqiNP_079664.1. NM_025388.2.
UniGeneiMm.2815.

3D structure databases

ProteinModelPortaliQ9CR09.
SMRiQ9CR09. Positions 1-163.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

IntActiQ9CR09. 5 interactions.
MINTiMINT-217621.
STRINGi10090.ENSMUSP00000078914.

PTM databases

iPTMnetiQ9CR09.
PhosphoSiteiQ9CR09.

Proteomic databases

EPDiQ9CR09.
MaxQBiQ9CR09.
PaxDbiQ9CR09.
PeptideAtlasiQ9CR09.
PRIDEiQ9CR09.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000080001; ENSMUSP00000078914; ENSMUSG00000062963.
ENSMUST00000111302; ENSMUSP00000106933; ENSMUSG00000062963.
GeneIDi66155.
KEGGimmu:66155.
UCSCiuc007dnw.1. mouse.

Organism-specific databases

CTDi51506.
MGIiMGI:1913405. Ufc1.

Phylogenomic databases

eggNOGiKOG3357. Eukaryota.
ENOG410ZBCX. LUCA.
GeneTreeiENSGT00390000008196.
HOGENOMiHOG000243361.
HOVERGENiHBG054254.
InParanoidiQ9CR09.
KOiK12165.
OMAiEHFKPLW.
OrthoDBiEOG091G0MP6.
PhylomeDBiQ9CR09.
TreeFamiTF313587.

Miscellaneous databases

ChiTaRSiUfc1. mouse.
PROiQ9CR09.
SOURCEiSearch...

Gene expression databases

BgeeiENSMUSG00000062963.
CleanExiMM_UFC1.
ExpressionAtlasiQ9CR09. baseline and differential.
GenevisibleiQ9CR09. MM.

Family and domain databases

InterProiIPR016135. UBQ-conjugating_enzyme/RWD.
IPR014806. Ufc1.
[Graphical view]
PANTHERiPTHR12921. PTHR12921. 1 hit.
PfamiPF08694. UFC1. 1 hit.
[Graphical view]
PIRSFiPIRSF008716. DUF1782. 1 hit.
SUPFAMiSSF54495. SSF54495. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiUFC1_MOUSE
AccessioniPrimary (citable) accession number: Q9CR09
Entry historyi
Integrated into UniProtKB/Swiss-Prot: April 26, 2005
Last sequence update: June 1, 2001
Last modified: September 7, 2016
This is version 101 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.