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Q9CQY9

- NDUC1_MOUSE

UniProt

Q9CQY9 - NDUC1_MOUSE

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Protein

NADH dehydrogenase [ubiquinone] 1 subunit C1, mitochondrial

Gene

Ndufc1

Organism
Mus musculus (Mouse)
Status
Reviewed - Annotation score: 3 out of 5- Protein inferred from homologyi

Functioni

Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone By similarity.By similarity

GO - Biological processi

  1. oxidation-reduction process Source: UniProtKB-KW
Complete GO annotation...

Keywords - Biological processi

Electron transport, Respiratory chain, Transport

Names & Taxonomyi

Protein namesi
Recommended name:
NADH dehydrogenase [ubiquinone] 1 subunit C1, mitochondrial
Alternative name(s):
Complex I-KFYI
Short name:
CI-KFYI
NADH-ubiquinone oxidoreductase KFYI subunit
Gene namesi
Name:Ndufc1
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
ProteomesiUP000000589: Chromosome 3

Organism-specific databases

MGIiMGI:1913627. Ndufc1.

Subcellular locationi

Mitochondrion inner membrane By similarity; Single-pass membrane protein By similarity; Matrix side By similarity

GO - Cellular componenti

  1. integral component of membrane Source: UniProtKB-KW
  2. mitochondrial respiratory chain complex I Source: InterPro
  3. mitochondrion Source: MGI
Complete GO annotation...

Keywords - Cellular componenti

Membrane, Mitochondrion, Mitochondrion inner membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transit peptidei1 – 2727MitochondrionBy similarityAdd
BLAST
Chaini28 – 7649NADH dehydrogenase [ubiquinone] 1 subunit C1, mitochondrialPRO_0000020050Add
BLAST

Proteomic databases

MaxQBiQ9CQY9.
PRIDEiQ9CQY9.

Expressioni

Gene expression databases

BgeeiQ9CQY9.
GenevestigatoriQ9CQY9.

Interactioni

Subunit structurei

Complex I is composed of 45 different subunits.By similarity

Structurei

Transmembrane

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei40 – 5920HelicalSequence AnalysisAdd
BLAST

Family & Domainsi

Sequence similaritiesi

Belongs to the complex I NDUFC1 subunit family.Curated

Keywords - Domaini

Transit peptide, Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiNOG43351.
GeneTreeiENSGT00390000002565.
HOGENOMiHOG000013086.
HOVERGENiHBG006500.
InParanoidiQ9CQY9.
KOiK03967.
OMAiNAKPDWL.
OrthoDBiEOG7T4MP8.
PhylomeDBiQ9CQY9.
TreeFamiTF338333.

Family and domain databases

InterProiIPR026192. NDUFC1.
[Graphical view]
PANTHERiPTHR17097. PTHR17097. 1 hit.
PfamiPF15088. NADH_dh_m_C1. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q9CQY9-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MAPSVVLRSF SRLLAPARLP SCSSTRSKFY VREPVNAKPN WLAVGLSVGA
60 70
SVFMWIYLIQ THNEDVLEYK RRNGLE
Length:76
Mass (Da):8,625
Last modified:June 1, 2001 - v1
Checksum:i3EF9EE9B8D2367F8
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AK003365 mRNA. Translation: BAB22739.1.
AK009393 mRNA. Translation: BAB26262.1.
AK018705 mRNA. Translation: BAB31356.1.
AK028011 mRNA. Translation: BAC25698.1.
BC092141 mRNA. Translation: AAH92141.1.
CCDSiCCDS38426.1.
RefSeqiNP_079799.1. NM_025523.1.
UniGeneiMm.331007.

Genome annotation databases

EnsembliENSMUST00000038108; ENSMUSP00000038463; ENSMUSG00000037152.
GeneIDi66377.
KEGGimmu:66377.
UCSCiuc008pdy.1. mouse.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AK003365 mRNA. Translation: BAB22739.1 .
AK009393 mRNA. Translation: BAB26262.1 .
AK018705 mRNA. Translation: BAB31356.1 .
AK028011 mRNA. Translation: BAC25698.1 .
BC092141 mRNA. Translation: AAH92141.1 .
CCDSi CCDS38426.1.
RefSeqi NP_079799.1. NM_025523.1.
UniGenei Mm.331007.

3D structure databases

ModBasei Search...
MobiDBi Search...

Proteomic databases

MaxQBi Q9CQY9.
PRIDEi Q9CQY9.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENSMUST00000038108 ; ENSMUSP00000038463 ; ENSMUSG00000037152 .
GeneIDi 66377.
KEGGi mmu:66377.
UCSCi uc008pdy.1. mouse.

Organism-specific databases

CTDi 4717.
MGIi MGI:1913627. Ndufc1.

Phylogenomic databases

eggNOGi NOG43351.
GeneTreei ENSGT00390000002565.
HOGENOMi HOG000013086.
HOVERGENi HBG006500.
InParanoidi Q9CQY9.
KOi K03967.
OMAi NAKPDWL.
OrthoDBi EOG7T4MP8.
PhylomeDBi Q9CQY9.
TreeFami TF338333.

Miscellaneous databases

ChiTaRSi NDUFC1. mouse.
NextBioi 321493.
PROi Q9CQY9.
SOURCEi Search...

Gene expression databases

Bgeei Q9CQY9.
Genevestigatori Q9CQY9.

Family and domain databases

InterProi IPR026192. NDUFC1.
[Graphical view ]
PANTHERi PTHR17097. PTHR17097. 1 hit.
Pfami PF15088. NADH_dh_m_C1. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "The transcriptional landscape of the mammalian genome."
    Carninci P., Kasukawa T., Katayama S., Gough J., Frith M.C., Maeda N., Oyama R., Ravasi T., Lenhard B., Wells C., Kodzius R., Shimokawa K., Bajic V.B., Brenner S.E., Batalov S., Forrest A.R., Zavolan M., Davis M.J.
    , Wilming L.G., Aidinis V., Allen J.E., Ambesi-Impiombato A., Apweiler R., Aturaliya R.N., Bailey T.L., Bansal M., Baxter L., Beisel K.W., Bersano T., Bono H., Chalk A.M., Chiu K.P., Choudhary V., Christoffels A., Clutterbuck D.R., Crowe M.L., Dalla E., Dalrymple B.P., de Bono B., Della Gatta G., di Bernardo D., Down T., Engstrom P., Fagiolini M., Faulkner G., Fletcher C.F., Fukushima T., Furuno M., Futaki S., Gariboldi M., Georgii-Hemming P., Gingeras T.R., Gojobori T., Green R.E., Gustincich S., Harbers M., Hayashi Y., Hensch T.K., Hirokawa N., Hill D., Huminiecki L., Iacono M., Ikeo K., Iwama A., Ishikawa T., Jakt M., Kanapin A., Katoh M., Kawasawa Y., Kelso J., Kitamura H., Kitano H., Kollias G., Krishnan S.P., Kruger A., Kummerfeld S.K., Kurochkin I.V., Lareau L.F., Lazarevic D., Lipovich L., Liu J., Liuni S., McWilliam S., Madan Babu M., Madera M., Marchionni L., Matsuda H., Matsuzawa S., Miki H., Mignone F., Miyake S., Morris K., Mottagui-Tabar S., Mulder N., Nakano N., Nakauchi H., Ng P., Nilsson R., Nishiguchi S., Nishikawa S., Nori F., Ohara O., Okazaki Y., Orlando V., Pang K.C., Pavan W.J., Pavesi G., Pesole G., Petrovsky N., Piazza S., Reed J., Reid J.F., Ring B.Z., Ringwald M., Rost B., Ruan Y., Salzberg S.L., Sandelin A., Schneider C., Schoenbach C., Sekiguchi K., Semple C.A., Seno S., Sessa L., Sheng Y., Shibata Y., Shimada H., Shimada K., Silva D., Sinclair B., Sperling S., Stupka E., Sugiura K., Sultana R., Takenaka Y., Taki K., Tammoja K., Tan S.L., Tang S., Taylor M.S., Tegner J., Teichmann S.A., Ueda H.R., van Nimwegen E., Verardo R., Wei C.L., Yagi K., Yamanishi H., Zabarovsky E., Zhu S., Zimmer A., Hide W., Bult C., Grimmond S.M., Teasdale R.D., Liu E.T., Brusic V., Quackenbush J., Wahlestedt C., Mattick J.S., Hume D.A., Kai C., Sasaki D., Tomaru Y., Fukuda S., Kanamori-Katayama M., Suzuki M., Aoki J., Arakawa T., Iida J., Imamura K., Itoh M., Kato T., Kawaji H., Kawagashira N., Kawashima T., Kojima M., Kondo S., Konno H., Nakano K., Ninomiya N., Nishio T., Okada M., Plessy C., Shibata K., Shiraki T., Suzuki S., Tagami M., Waki K., Watahiki A., Okamura-Oho Y., Suzuki H., Kawai J., Hayashizaki Y.
    Science 309:1559-1563(2005) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Strain: C57BL/6J.
    Tissue: Embryo, Kidney and Tongue.
  2. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Strain: C57BL/6.
    Tissue: Brain.

Entry informationi

Entry nameiNDUC1_MOUSE
AccessioniPrimary (citable) accession number: Q9CQY9
Secondary accession number(s): Q58DY9
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 10, 2004
Last sequence update: June 1, 2001
Last modified: October 29, 2014
This is version 86 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3