Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Galectin-2

Gene

Lgals2

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

This protein binds beta-galactoside. Its physiological function is not yet known.

GO - Molecular functioni

Complete GO annotation...

Keywords - Ligandi

Lectin

Names & Taxonomyi

Protein namesi
Recommended name:
Galectin-2
Short name:
Gal-2
Gene namesi
Name:Lgals2
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 15

Organism-specific databases

MGIiMGI:895068. Lgals2.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 130130Galectin-2PRO_0000076925Add
BLAST

Proteomic databases

MaxQBiQ9CQW5.
PaxDbiQ9CQW5.
PeptideAtlasiQ9CQW5.
PRIDEiQ9CQW5.

PTM databases

PhosphoSiteiQ9CQW5.

Expressioni

Gene expression databases

BgeeiENSMUSG00000043501.
CleanExiMM_LGALS2.
GenevisibleiQ9CQW5. MM.

Interactioni

Subunit structurei

Homodimer.By similarity

Protein-protein interaction databases

IntActiQ9CQW5. 3 interactions.
STRINGi10090.ENSMUSP00000036598.

Structurei

3D structure databases

ProteinModelPortaliQ9CQW5.
SMRiQ9CQW5. Positions 4-130.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini4 – 130127GalectinPROSITE-ProRule annotationAdd
BLAST

Region

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Regioni65 – 717Beta-galactoside bindingSequence analysis

Sequence similaritiesi

Contains 1 galectin domain.PROSITE-ProRule annotation

Phylogenomic databases

eggNOGiKOG3587. Eukaryota.
ENOG4111EA0. LUCA.
GeneTreeiENSGT00440000034263.
HOGENOMiHOG000059539.
HOVERGENiHBG006255.
InParanoidiQ9CQW5.
KOiK10090.
OMAiLNLHFNP.
OrthoDBiEOG091G0S7H.
PhylomeDBiQ9CQW5.
TreeFamiTF315551.

Family and domain databases

Gene3Di2.60.120.200. 1 hit.
InterProiIPR013320. ConA-like_dom.
IPR001079. Galectin_CRD.
[Graphical view]
PfamiPF00337. Gal-bind_lectin. 1 hit.
[Graphical view]
SMARTiSM00908. Gal-bind_lectin. 1 hit.
SM00276. GLECT. 1 hit.
[Graphical view]
SUPFAMiSSF49899. SSF49899. 1 hit.
PROSITEiPS51304. GALECTIN. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q9CQW5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSEKFEVKDL NMKPGMSLKI KGKIHNDVDR FLINLGQGKE TLNLHFNPRF
60 70 80 90 100
DESTIVCNTS EGGRWGQEQR ENHMCFSPGS EVKITITFQD KDFKVTLPDG
110 120 130
HQLTFPNRLG HNQLHYLSMG GLQISSFKLE
Length:130
Mass (Da):14,880
Last modified:April 27, 2001 - v1
Checksum:i4E5EA89F3E0C36FD
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sequence conflicti36 – 361G → V in BAB25806 (PubMed:16141072).Curated
Sequence conflicti106 – 1061P → R in BAB25661 (PubMed:16141072).Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK007364 mRNA. Translation: BAB24987.1.
AK008423 mRNA. Translation: BAB25661.1.
AK008636 mRNA. Translation: BAB25797.1.
AK008648 mRNA. Translation: BAB25806.1.
CCDSiCCDS37135.1.
RefSeqiNP_079898.2. NM_025622.3.
UniGeneiMm.390793.

Genome annotation databases

EnsembliENSMUST00000044584; ENSMUSP00000036598; ENSMUSG00000043501.
GeneIDi107753.
KEGGimmu:107753.
UCSCiuc007wrm.2. mouse.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK007364 mRNA. Translation: BAB24987.1.
AK008423 mRNA. Translation: BAB25661.1.
AK008636 mRNA. Translation: BAB25797.1.
AK008648 mRNA. Translation: BAB25806.1.
CCDSiCCDS37135.1.
RefSeqiNP_079898.2. NM_025622.3.
UniGeneiMm.390793.

3D structure databases

ProteinModelPortaliQ9CQW5.
SMRiQ9CQW5. Positions 4-130.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

IntActiQ9CQW5. 3 interactions.
STRINGi10090.ENSMUSP00000036598.

PTM databases

PhosphoSiteiQ9CQW5.

Proteomic databases

MaxQBiQ9CQW5.
PaxDbiQ9CQW5.
PeptideAtlasiQ9CQW5.
PRIDEiQ9CQW5.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000044584; ENSMUSP00000036598; ENSMUSG00000043501.
GeneIDi107753.
KEGGimmu:107753.
UCSCiuc007wrm.2. mouse.

Organism-specific databases

CTDi3957.
MGIiMGI:895068. Lgals2.

Phylogenomic databases

eggNOGiKOG3587. Eukaryota.
ENOG4111EA0. LUCA.
GeneTreeiENSGT00440000034263.
HOGENOMiHOG000059539.
HOVERGENiHBG006255.
InParanoidiQ9CQW5.
KOiK10090.
OMAiLNLHFNP.
OrthoDBiEOG091G0S7H.
PhylomeDBiQ9CQW5.
TreeFamiTF315551.

Miscellaneous databases

PROiQ9CQW5.
SOURCEiSearch...

Gene expression databases

BgeeiENSMUSG00000043501.
CleanExiMM_LGALS2.
GenevisibleiQ9CQW5. MM.

Family and domain databases

Gene3Di2.60.120.200. 1 hit.
InterProiIPR013320. ConA-like_dom.
IPR001079. Galectin_CRD.
[Graphical view]
PfamiPF00337. Gal-bind_lectin. 1 hit.
[Graphical view]
SMARTiSM00908. Gal-bind_lectin. 1 hit.
SM00276. GLECT. 1 hit.
[Graphical view]
SUPFAMiSSF49899. SSF49899. 1 hit.
PROSITEiPS51304. GALECTIN. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiLEG2_MOUSE
AccessioniPrimary (citable) accession number: Q9CQW5
Secondary accession number(s): Q9D800, Q9D862
Entry historyi
Integrated into UniProtKB/Swiss-Prot: April 27, 2001
Last sequence update: April 27, 2001
Last modified: September 7, 2016
This is version 108 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.