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Protein

RNA-binding protein 7

Gene

Rbm7

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

Possible involved in germ cell RNA processing and meiosis.By similarity

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Biological processi

Meiosis

Keywords - Ligandi

RNA-binding

Names & Taxonomyi

Protein namesi
Recommended name:
RNA-binding protein 7
Alternative name(s):
RNA-binding motif protein 7
Gene namesi
Name:Rbm7
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 9

Organism-specific databases

MGIiMGI:1914260. Rbm7.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 265265RNA-binding protein 7PRO_0000081762Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei137 – 1371PhosphoserineCombined sources
Modified residuei203 – 2031PhosphoserineBy similarity

Keywords - PTMi

Phosphoprotein

Proteomic databases

EPDiQ9CQT2.
MaxQBiQ9CQT2.
PaxDbiQ9CQT2.
PRIDEiQ9CQT2.

PTM databases

iPTMnetiQ9CQT2.
PhosphoSiteiQ9CQT2.

Expressioni

Gene expression databases

BgeeiQ9CQT2.
CleanExiMM_RBM7.
ExpressionAtlasiQ9CQT2. baseline and differential.
GenevisibleiQ9CQT2. MM.

Interactioni

Protein-protein interaction databases

IntActiQ9CQT2. 2 interactions.
MINTiMINT-4131940.
STRINGi10090.ENSMUSP00000126374.

Structurei

3D structure databases

ProteinModelPortaliQ9CQT2.
SMRiQ9CQT2. Positions 4-94.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini10 – 8778RRMPROSITE-ProRule annotationAdd
BLAST

Sequence similaritiesi

Contains 1 RRM (RNA recognition motif) domain.PROSITE-ProRule annotation

Phylogenomic databases

eggNOGiKOG4454. Eukaryota.
ENOG41123B7. LUCA.
GeneTreeiENSGT00840000129882.
HOGENOMiHOG000059553.
HOVERGENiHBG009324.
InParanoidiQ9CQT2.
KOiK13188.
OMAiDRHYSRE.
OrthoDBiEOG7HB5BD.
PhylomeDBiQ9CQT2.
TreeFamiTF323596.

Family and domain databases

Gene3Di3.30.70.330. 1 hit.
InterProiIPR012677. Nucleotide-bd_a/b_plait.
IPR000504. RRM_dom.
[Graphical view]
PfamiPF00076. RRM_1. 1 hit.
[Graphical view]
SMARTiSM00360. RRM. 1 hit.
[Graphical view]
SUPFAMiSSF54928. SSF54928. 1 hit.
PROSITEiPS50102. RRM. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q9CQT2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGAAAAEADR TLFVGNLETK VTEELLFELF HQAGPVIKVK IPKDKDGKLK
60 70 80 90 100
QFAFVNFKHE VSVPYAMNLL NGIKLFGRPI KIQFRSGSSH ASQDASVSYP
110 120 130 140 150
QHHVGNLSPT STSPNSYERT VGNVSPTAQM VQRSFSSPED YQRQAVMNSV
160 170 180 190 200
FRQMSYAGKF GSPHADQLGF SPSAQPHGHT FNQSSSSQWR QDALSSQRKR
210 220 230 240 250
QNSHPYLADR HYSREQRYSD HGSDYHYRGS REDFYYDDRN HDGWSHDYDN
260
RRDSSRGGKW PSSRH
Length:265
Mass (Da):30,148
Last modified:June 1, 2001 - v1
Checksum:i5D99650FD1FBF0C8
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sequence conflicti240 – 2401N → D in AAH54774 (PubMed:15489334).Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF458961 mRNA. Translation: AAL60585.1.
AK005200 mRNA. Translation: BAB23878.1.
AK006755 mRNA. Translation: BAB24729.1.
AK008645 mRNA. Translation: BAB25804.1.
AK151056 mRNA. Translation: BAE30073.1.
BC054774 mRNA. Translation: AAH54774.1.
CCDSiCCDS23155.1.
RefSeqiNP_659197.2. NM_144948.5.
UniGeneiMm.76911.

Genome annotation databases

EnsembliENSMUST00000170000; ENSMUSP00000126374; ENSMUSG00000042396.
GeneIDi67010.
KEGGimmu:67010.
UCSCiuc009pic.2. mouse.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF458961 mRNA. Translation: AAL60585.1.
AK005200 mRNA. Translation: BAB23878.1.
AK006755 mRNA. Translation: BAB24729.1.
AK008645 mRNA. Translation: BAB25804.1.
AK151056 mRNA. Translation: BAE30073.1.
BC054774 mRNA. Translation: AAH54774.1.
CCDSiCCDS23155.1.
RefSeqiNP_659197.2. NM_144948.5.
UniGeneiMm.76911.

3D structure databases

ProteinModelPortaliQ9CQT2.
SMRiQ9CQT2. Positions 4-94.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

IntActiQ9CQT2. 2 interactions.
MINTiMINT-4131940.
STRINGi10090.ENSMUSP00000126374.

PTM databases

iPTMnetiQ9CQT2.
PhosphoSiteiQ9CQT2.

Proteomic databases

EPDiQ9CQT2.
MaxQBiQ9CQT2.
PaxDbiQ9CQT2.
PRIDEiQ9CQT2.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000170000; ENSMUSP00000126374; ENSMUSG00000042396.
GeneIDi67010.
KEGGimmu:67010.
UCSCiuc009pic.2. mouse.

Organism-specific databases

CTDi10179.
MGIiMGI:1914260. Rbm7.

Phylogenomic databases

eggNOGiKOG4454. Eukaryota.
ENOG41123B7. LUCA.
GeneTreeiENSGT00840000129882.
HOGENOMiHOG000059553.
HOVERGENiHBG009324.
InParanoidiQ9CQT2.
KOiK13188.
OMAiDRHYSRE.
OrthoDBiEOG7HB5BD.
PhylomeDBiQ9CQT2.
TreeFamiTF323596.

Miscellaneous databases

PROiQ9CQT2.
SOURCEiSearch...

Gene expression databases

BgeeiQ9CQT2.
CleanExiMM_RBM7.
ExpressionAtlasiQ9CQT2. baseline and differential.
GenevisibleiQ9CQT2. MM.

Family and domain databases

Gene3Di3.30.70.330. 1 hit.
InterProiIPR012677. Nucleotide-bd_a/b_plait.
IPR000504. RRM_dom.
[Graphical view]
PfamiPF00076. RRM_1. 1 hit.
[Graphical view]
SMARTiSM00360. RRM. 1 hit.
[Graphical view]
SUPFAMiSSF54928. SSF54928. 1 hit.
PROSITEiPS50102. RRM. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. "RNA binding motif protein 7, a novel ubiquitous protein involved in pre-mRNA processing during male meiosis."
    Guo T.B., Kato M.V., Boros L.G., Chan K.C., Sinha Hikim A.P., Hudson A.P., Swerdloff R.S., Mitchell A.P., Lin R.-J., Salameh W.A.
    Submitted (DEC-2001) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [MRNA].
    Strain: C57BL/6J.
  2. "The transcriptional landscape of the mammalian genome."
    Carninci P., Kasukawa T., Katayama S., Gough J., Frith M.C., Maeda N., Oyama R., Ravasi T., Lenhard B., Wells C., Kodzius R., Shimokawa K., Bajic V.B., Brenner S.E., Batalov S., Forrest A.R., Zavolan M., Davis M.J.
    , Wilming L.G., Aidinis V., Allen J.E., Ambesi-Impiombato A., Apweiler R., Aturaliya R.N., Bailey T.L., Bansal M., Baxter L., Beisel K.W., Bersano T., Bono H., Chalk A.M., Chiu K.P., Choudhary V., Christoffels A., Clutterbuck D.R., Crowe M.L., Dalla E., Dalrymple B.P., de Bono B., Della Gatta G., di Bernardo D., Down T., Engstrom P., Fagiolini M., Faulkner G., Fletcher C.F., Fukushima T., Furuno M., Futaki S., Gariboldi M., Georgii-Hemming P., Gingeras T.R., Gojobori T., Green R.E., Gustincich S., Harbers M., Hayashi Y., Hensch T.K., Hirokawa N., Hill D., Huminiecki L., Iacono M., Ikeo K., Iwama A., Ishikawa T., Jakt M., Kanapin A., Katoh M., Kawasawa Y., Kelso J., Kitamura H., Kitano H., Kollias G., Krishnan S.P., Kruger A., Kummerfeld S.K., Kurochkin I.V., Lareau L.F., Lazarevic D., Lipovich L., Liu J., Liuni S., McWilliam S., Madan Babu M., Madera M., Marchionni L., Matsuda H., Matsuzawa S., Miki H., Mignone F., Miyake S., Morris K., Mottagui-Tabar S., Mulder N., Nakano N., Nakauchi H., Ng P., Nilsson R., Nishiguchi S., Nishikawa S., Nori F., Ohara O., Okazaki Y., Orlando V., Pang K.C., Pavan W.J., Pavesi G., Pesole G., Petrovsky N., Piazza S., Reed J., Reid J.F., Ring B.Z., Ringwald M., Rost B., Ruan Y., Salzberg S.L., Sandelin A., Schneider C., Schoenbach C., Sekiguchi K., Semple C.A., Seno S., Sessa L., Sheng Y., Shibata Y., Shimada H., Shimada K., Silva D., Sinclair B., Sperling S., Stupka E., Sugiura K., Sultana R., Takenaka Y., Taki K., Tammoja K., Tan S.L., Tang S., Taylor M.S., Tegner J., Teichmann S.A., Ueda H.R., van Nimwegen E., Verardo R., Wei C.L., Yagi K., Yamanishi H., Zabarovsky E., Zhu S., Zimmer A., Hide W., Bult C., Grimmond S.M., Teasdale R.D., Liu E.T., Brusic V., Quackenbush J., Wahlestedt C., Mattick J.S., Hume D.A., Kai C., Sasaki D., Tomaru Y., Fukuda S., Kanamori-Katayama M., Suzuki M., Aoki J., Arakawa T., Iida J., Imamura K., Itoh M., Kato T., Kawaji H., Kawagashira N., Kawashima T., Kojima M., Kondo S., Konno H., Nakano K., Ninomiya N., Nishio T., Okada M., Plessy C., Shibata K., Shiraki T., Suzuki S., Tagami M., Waki K., Watahiki A., Okamura-Oho Y., Suzuki H., Kawai J., Hayashizaki Y.
    Science 309:1559-1563(2005) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Strain: C57BL/6J.
    Tissue: Bone marrow, Cerebellum, Stomach and Testis.
  3. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Strain: C57BL/6J.
    Tissue: Brain.
  4. Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-137, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
    Tissue: Kidney, Spleen and Testis.

Entry informationi

Entry nameiRBM7_MOUSE
AccessioniPrimary (citable) accession number: Q9CQT2
Secondary accession number(s): Q3UB91, Q7TQE3
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 23, 2004
Last sequence update: June 1, 2001
Last modified: June 8, 2016
This is version 107 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.