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Q9CQR2

- RS21_MOUSE

UniProt

Q9CQR2 - RS21_MOUSE

Protein

40S ribosomal protein S21

Gene

Rps21

Organism
Mus musculus (Mouse)
Status
Reviewed - Annotation score: 2 out of 5- Experimental evidence at transcript leveli
  1. Functioni

    GO - Molecular functioni

    1. ribosome binding Source: UniProtKB
    2. structural constituent of ribosome Source: RefGenome

    GO - Biological processi

    1. endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) Source: RefGenome
    2. endonucleolytic cleavage to generate mature 3'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA) Source: RefGenome
    3. ribosomal small subunit biogenesis Source: RefGenome
    4. translational elongation Source: RefGenome

    Keywords - Molecular functioni

    Ribonucleoprotein, Ribosomal protein

    Enzyme and pathway databases

    ReactomeiREACT_196445. SRP-dependent cotranslational protein targeting to membrane.
    REACT_198524. Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC).
    REACT_198528. Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC).

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    40S ribosomal protein S21
    Gene namesi
    Name:Rps21
    OrganismiMus musculus (Mouse)
    Taxonomic identifieri10090 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
    ProteomesiUP000000589: Chromosome 2

    Organism-specific databases

    MGIiMGI:1913731. Rps21.

    Subcellular locationi

    GO - Cellular componenti

    1. cytosolic small ribosomal subunit Source: RefGenome

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 838340S ribosomal protein S21PRO_0000194731Add
    BLAST

    Amino acid modifications

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Modified residuei1 – 11N-acetylmethionineBy similarity
    Modified residuei81 – 811N6-acetyllysineBy similarity

    Keywords - PTMi

    Acetylation

    Proteomic databases

    MaxQBiQ9CQR2.
    PaxDbiQ9CQR2.
    PRIDEiQ9CQR2.

    PTM databases

    PhosphoSiteiQ9CQR2.

    Expressioni

    Gene expression databases

    BgeeiQ9CQR2.
    CleanExiMM_RPS21.
    GenevestigatoriQ9CQR2.

    Interactioni

    Protein-protein interaction databases

    MINTiMINT-1857339.

    Structurei

    3D structure databases

    ProteinModelPortaliQ9CQR2.
    SMRiQ9CQR2. Positions 1-82.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the ribosomal protein S21e family.Curated

    Phylogenomic databases

    eggNOGiNOG301320.
    GeneTreeiENSGT00390000017515.
    HOGENOMiHOG000183557.
    HOVERGENiHBG005025.
    InParanoidiQ9CQR2.
    KOiK02971.
    OMAiGLNSTHH.
    OrthoDBiEOG7HQNBQ.
    PhylomeDBiQ9CQR2.
    TreeFamiTF300167.

    Family and domain databases

    InterProiIPR001931. Ribosomal_S21e.
    IPR018279. Ribosomal_S21e_CS.
    [Graphical view]
    PANTHERiPTHR10442. PTHR10442. 1 hit.
    PfamiPF01249. Ribosomal_S21e. 1 hit.
    [Graphical view]
    PIRSFiPIRSF002148. Ribosomal_S21e. 1 hit.
    ProDomiPD006584. Ribosomal_S21e. 1 hit.
    [Graphical view] [Entries sharing at least one domain]
    PROSITEiPS00996. RIBOSOMAL_S21E. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q9CQR2-1 [UniParc]FASTAAdd to Basket

    « Hide

    MQNDAGEFVD LYVPRKCSAS NRIIAAKDHA SIQMNVAEVD RTTGRFNGQF   50
    KTYGICGAIR RMGESDDSIL RLAKADGIVS KNF 83
    Length:83
    Mass (Da):9,141
    Last modified:June 1, 2001 - v1
    Checksum:i67961651844D0DB5
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AK007846 mRNA. Translation: BAB25301.1.
    AK007850 mRNA. Translation: BAB25304.1.
    AK010637 mRNA. Translation: BAB27081.1.
    AK012488 mRNA. Translation: BAB28274.1.
    BC027563 mRNA. Translation: AAH27563.1.
    BC086912 mRNA. Translation: AAH86912.1.
    CCDSiCCDS38376.1.
    RefSeqiNP_079863.1. NM_025587.2.
    XP_006500765.1. XM_006500702.1.
    UniGeneiMm.289669.

    Genome annotation databases

    EnsembliENSMUST00000059080; ENSMUSP00000058432; ENSMUSG00000039001.
    GeneIDi66481.
    KEGGimmu:66481.
    UCSCiuc008oiq.1. mouse.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AK007846 mRNA. Translation: BAB25301.1 .
    AK007850 mRNA. Translation: BAB25304.1 .
    AK010637 mRNA. Translation: BAB27081.1 .
    AK012488 mRNA. Translation: BAB28274.1 .
    BC027563 mRNA. Translation: AAH27563.1 .
    BC086912 mRNA. Translation: AAH86912.1 .
    CCDSi CCDS38376.1.
    RefSeqi NP_079863.1. NM_025587.2.
    XP_006500765.1. XM_006500702.1.
    UniGenei Mm.289669.

    3D structure databases

    ProteinModelPortali Q9CQR2.
    SMRi Q9CQR2. Positions 1-82.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    MINTi MINT-1857339.

    PTM databases

    PhosphoSitei Q9CQR2.

    Proteomic databases

    MaxQBi Q9CQR2.
    PaxDbi Q9CQR2.
    PRIDEi Q9CQR2.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    Ensembli ENSMUST00000059080 ; ENSMUSP00000058432 ; ENSMUSG00000039001 .
    GeneIDi 66481.
    KEGGi mmu:66481.
    UCSCi uc008oiq.1. mouse.

    Organism-specific databases

    CTDi 6227.
    MGIi MGI:1913731. Rps21.

    Phylogenomic databases

    eggNOGi NOG301320.
    GeneTreei ENSGT00390000017515.
    HOGENOMi HOG000183557.
    HOVERGENi HBG005025.
    InParanoidi Q9CQR2.
    KOi K02971.
    OMAi GLNSTHH.
    OrthoDBi EOG7HQNBQ.
    PhylomeDBi Q9CQR2.
    TreeFami TF300167.

    Enzyme and pathway databases

    Reactomei REACT_196445. SRP-dependent cotranslational protein targeting to membrane.
    REACT_198524. Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC).
    REACT_198528. Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC).

    Miscellaneous databases

    ChiTaRSi RpS21. mouse.
    NextBioi 321812.
    PROi Q9CQR2.
    SOURCEi Search...

    Gene expression databases

    Bgeei Q9CQR2.
    CleanExi MM_RPS21.
    Genevestigatori Q9CQR2.

    Family and domain databases

    InterProi IPR001931. Ribosomal_S21e.
    IPR018279. Ribosomal_S21e_CS.
    [Graphical view ]
    PANTHERi PTHR10442. PTHR10442. 1 hit.
    Pfami PF01249. Ribosomal_S21e. 1 hit.
    [Graphical view ]
    PIRSFi PIRSF002148. Ribosomal_S21e. 1 hit.
    ProDomi PD006584. Ribosomal_S21e. 1 hit.
    [Graphical view ] [Entries sharing at least one domain ]
    PROSITEi PS00996. RIBOSOMAL_S21E. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "The transcriptional landscape of the mammalian genome."
      Carninci P., Kasukawa T., Katayama S., Gough J., Frith M.C., Maeda N., Oyama R., Ravasi T., Lenhard B., Wells C., Kodzius R., Shimokawa K., Bajic V.B., Brenner S.E., Batalov S., Forrest A.R., Zavolan M., Davis M.J.
      , Wilming L.G., Aidinis V., Allen J.E., Ambesi-Impiombato A., Apweiler R., Aturaliya R.N., Bailey T.L., Bansal M., Baxter L., Beisel K.W., Bersano T., Bono H., Chalk A.M., Chiu K.P., Choudhary V., Christoffels A., Clutterbuck D.R., Crowe M.L., Dalla E., Dalrymple B.P., de Bono B., Della Gatta G., di Bernardo D., Down T., Engstrom P., Fagiolini M., Faulkner G., Fletcher C.F., Fukushima T., Furuno M., Futaki S., Gariboldi M., Georgii-Hemming P., Gingeras T.R., Gojobori T., Green R.E., Gustincich S., Harbers M., Hayashi Y., Hensch T.K., Hirokawa N., Hill D., Huminiecki L., Iacono M., Ikeo K., Iwama A., Ishikawa T., Jakt M., Kanapin A., Katoh M., Kawasawa Y., Kelso J., Kitamura H., Kitano H., Kollias G., Krishnan S.P., Kruger A., Kummerfeld S.K., Kurochkin I.V., Lareau L.F., Lazarevic D., Lipovich L., Liu J., Liuni S., McWilliam S., Madan Babu M., Madera M., Marchionni L., Matsuda H., Matsuzawa S., Miki H., Mignone F., Miyake S., Morris K., Mottagui-Tabar S., Mulder N., Nakano N., Nakauchi H., Ng P., Nilsson R., Nishiguchi S., Nishikawa S., Nori F., Ohara O., Okazaki Y., Orlando V., Pang K.C., Pavan W.J., Pavesi G., Pesole G., Petrovsky N., Piazza S., Reed J., Reid J.F., Ring B.Z., Ringwald M., Rost B., Ruan Y., Salzberg S.L., Sandelin A., Schneider C., Schoenbach C., Sekiguchi K., Semple C.A., Seno S., Sessa L., Sheng Y., Shibata Y., Shimada H., Shimada K., Silva D., Sinclair B., Sperling S., Stupka E., Sugiura K., Sultana R., Takenaka Y., Taki K., Tammoja K., Tan S.L., Tang S., Taylor M.S., Tegner J., Teichmann S.A., Ueda H.R., van Nimwegen E., Verardo R., Wei C.L., Yagi K., Yamanishi H., Zabarovsky E., Zhu S., Zimmer A., Hide W., Bult C., Grimmond S.M., Teasdale R.D., Liu E.T., Brusic V., Quackenbush J., Wahlestedt C., Mattick J.S., Hume D.A., Kai C., Sasaki D., Tomaru Y., Fukuda S., Kanamori-Katayama M., Suzuki M., Aoki J., Arakawa T., Iida J., Imamura K., Itoh M., Kato T., Kawaji H., Kawagashira N., Kawashima T., Kojima M., Kondo S., Konno H., Nakano K., Ninomiya N., Nishio T., Okada M., Plessy C., Shibata K., Shiraki T., Suzuki S., Tagami M., Waki K., Watahiki A., Okamura-Oho Y., Suzuki H., Kawai J., Hayashizaki Y.
      Science 309:1559-1563(2005) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
      Strain: C57BL/6J.
      Tissue: Embryo, Embryonic stem cell and Pancreas.
    2. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
      Tissue: Heart and Mammary gland.

    Entry informationi

    Entry nameiRS21_MOUSE
    AccessioniPrimary (citable) accession number: Q9CQR2
    Secondary accession number(s): Q5M9L3
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: July 26, 2002
    Last sequence update: June 1, 2001
    Last modified: October 1, 2014
    This is version 87 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programChordata Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. MGD cross-references
      Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
    2. Ribosomal proteins
      Ribosomal proteins families and list of entries
    3. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3