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Q9CQM8

- Q9CQM8_MOUSE

UniProt

Q9CQM8 - Q9CQM8_MOUSE

Protein
Submitted name:

60S ribosomal protein L21

Gene

Rpl21

Organism
Mus musculus (Mouse)
Status
Unreviewed - Annotation score: 1 out of 5- Experimental evidence at transcript leveli
  1. Functioni

    GO - Molecular functioni

    1. structural constituent of ribosome Source: InterPro

    GO - Biological processi

    1. translation Source: InterPro

    Keywords - Molecular functioni

    Ribonucleoprotein, Ribosomal proteinImported

    Enzyme and pathway databases

    ReactomeiREACT_196445. SRP-dependent cotranslational protein targeting to membrane.
    REACT_198524. Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC).
    REACT_198528. Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC).

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    60S ribosomal protein L21Imported
    Submitted name:
    MCG120646Imported
    Submitted name:
    MCG121646, isoform CRA_aImported
    Submitted name:
    MCG121688Imported
    Submitted name:
    MCG18971Imported
    Submitted name:
    Ribosomal protein L21Imported
    Submitted name:
    Rpl21 proteinImported
    Gene namesi
    Name:Rpl21Imported
    ORF Names:mCG_120646Imported, mCG_121646Imported, mCG_121688Imported, mCG_18971Imported
    OrganismiMus musculus (Mouse)Imported
    Taxonomic identifieri10090 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
    ProteomesiUP000000589: Chromosome 5

    Organism-specific databases

    MGIiMGI:1278340. Rpl21.

    Subcellular locationi

    GO - Cellular componenti

    1. ribosome Source: UniProtKB-KW

    Expressioni

    Gene expression databases

    GenevestigatoriQ9CQM8.

    Interactioni

    Protein-protein interaction databases

    MINTiMINT-4124952.

    Family & Domainsi

    Phylogenomic databases

    eggNOGiCOG2139.
    GeneTreeiENSGT00390000001293.
    HOVERGENiHBG001518.
    InParanoidiQ9CQM8.
    KOiK02889.
    OMAiGTGTIQK.
    OrthoDBiEOG7Z3F60.
    TreeFamiTF314640.

    Family and domain databases

    Gene3Di2.30.30.70. 1 hit.
    InterProiIPR001147. Ribosomal_L21e.
    IPR018259. Ribosomal_L21e_CS.
    IPR008991. Translation_prot_SH3-like.
    [Graphical view]
    PANTHERiPTHR20981. PTHR20981. 1 hit.
    PfamiPF01157. Ribosomal_L21e. 1 hit.
    [Graphical view]
    SUPFAMiSSF50104. SSF50104. 1 hit.
    PROSITEiPS01171. RIBOSOMAL_L21E. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q9CQM8-1 [UniParc]FASTAAdd to Basket

    « Hide

    MTNTKGKRRG TRYMFSRPFR KHGVVPLATY MRIYKKGDIV DIKGMGTVQK    50
    GMPHKCYHGK TGRVYNVTQH AVGIIVNKQV KGKILAKRIN VRIEHIKHSK 100
    SRDSFLKRVK ENDQKKKEAK EKGTWVQLKR QPAPPREAHF VRTNGKEPEL 150
    LEPIPYEFMA 160
    Length:160
    Mass (Da):18,579
    Last modified:June 1, 2001 - v1
    Checksum:i74F215B18EAFAC22
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AC124828 Genomic DNA. No translation available.
    BC086904 mRNA. Translation: AAH86904.1.
    BC086905 mRNA. Translation: AAH86905.1.
    BC086935 mRNA. Translation: AAH86935.1.
    BC089582 mRNA. Translation: AAH89582.1.
    BC090256 mRNA. Translation: AAH90256.1.
    BC094410 mRNA. Translation: AAH94410.1.
    BC096404 mRNA. Translation: AAH96404.1.
    BC106116 mRNA. Translation: AAI06117.1.
    BC138299 mRNA. Translation: AAI38300.1.
    BC138300 mRNA. Translation: AAI38301.1.
    AK002940 mRNA. Translation: BAB22470.1.
    AK008457 mRNA. Translation: BAB25679.1.
    AK018480 mRNA. Translation: BAB31230.1.
    AK146440 mRNA. Translation: BAE27174.1.
    AK168998 mRNA. Translation: BAE40797.1.
    CH466614 Genomic DNA. Translation: EDL05813.1.
    CH466614 Genomic DNA. Translation: EDL05816.1.
    CH466641 Genomic DNA. Translation: EDL07492.1.
    CH466570 Genomic DNA. Translation: EDL29058.1.
    CH466545 Genomic DNA. Translation: EDL29396.1.
    RefSeqiNP_062621.2. NM_019647.6.
    XP_006504878.1. XM_006504815.1.
    XP_006504879.1. XM_006504816.1.
    UniGeneiMm.316592.
    Mm.371575.
    Mm.440507.

    Genome annotation databases

    EnsembliENSMUST00000035983; ENSMUSP00000041652; ENSMUSG00000041453.
    ENSMUST00000075453; ENSMUSP00000106213; ENSMUSG00000041453.
    ENSMUST00000099272; ENSMUSP00000106211; ENSMUSG00000041453.
    GeneIDi19933.
    KEGGimmu:19933.
    UCSCiuc009ank.2. mouse.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AC124828 Genomic DNA. No translation available.
    BC086904 mRNA. Translation: AAH86904.1 .
    BC086905 mRNA. Translation: AAH86905.1 .
    BC086935 mRNA. Translation: AAH86935.1 .
    BC089582 mRNA. Translation: AAH89582.1 .
    BC090256 mRNA. Translation: AAH90256.1 .
    BC094410 mRNA. Translation: AAH94410.1 .
    BC096404 mRNA. Translation: AAH96404.1 .
    BC106116 mRNA. Translation: AAI06117.1 .
    BC138299 mRNA. Translation: AAI38300.1 .
    BC138300 mRNA. Translation: AAI38301.1 .
    AK002940 mRNA. Translation: BAB22470.1 .
    AK008457 mRNA. Translation: BAB25679.1 .
    AK018480 mRNA. Translation: BAB31230.1 .
    AK146440 mRNA. Translation: BAE27174.1 .
    AK168998 mRNA. Translation: BAE40797.1 .
    CH466614 Genomic DNA. Translation: EDL05813.1 .
    CH466614 Genomic DNA. Translation: EDL05816.1 .
    CH466641 Genomic DNA. Translation: EDL07492.1 .
    CH466570 Genomic DNA. Translation: EDL29058.1 .
    CH466545 Genomic DNA. Translation: EDL29396.1 .
    RefSeqi NP_062621.2. NM_019647.6.
    XP_006504878.1. XM_006504815.1.
    XP_006504879.1. XM_006504816.1.
    UniGenei Mm.316592.
    Mm.371575.
    Mm.440507.

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    MINTi MINT-4124952.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    Ensembli ENSMUST00000035983 ; ENSMUSP00000041652 ; ENSMUSG00000041453 .
    ENSMUST00000075453 ; ENSMUSP00000106213 ; ENSMUSG00000041453 .
    ENSMUST00000099272 ; ENSMUSP00000106211 ; ENSMUSG00000041453 .
    GeneIDi 19933.
    KEGGi mmu:19933.
    UCSCi uc009ank.2. mouse.

    Organism-specific databases

    CTDi 6144.
    MGIi MGI:1278340. Rpl21.

    Phylogenomic databases

    eggNOGi COG2139.
    GeneTreei ENSGT00390000001293.
    HOVERGENi HBG001518.
    InParanoidi Q9CQM8.
    KOi K02889.
    OMAi GTGTIQK.
    OrthoDBi EOG7Z3F60.
    TreeFami TF314640.

    Enzyme and pathway databases

    Reactomei REACT_196445. SRP-dependent cotranslational protein targeting to membrane.
    REACT_198524. Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC).
    REACT_198528. Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC).

    Miscellaneous databases

    NextBioi 297441.
    SOURCEi Search...

    Gene expression databases

    Genevestigatori Q9CQM8.

    Family and domain databases

    Gene3Di 2.30.30.70. 1 hit.
    InterProi IPR001147. Ribosomal_L21e.
    IPR018259. Ribosomal_L21e_CS.
    IPR008991. Translation_prot_SH3-like.
    [Graphical view ]
    PANTHERi PTHR20981. PTHR20981. 1 hit.
    Pfami PF01157. Ribosomal_L21e. 1 hit.
    [Graphical view ]
    SUPFAMi SSF50104. SSF50104. 1 hit.
    PROSITEi PS01171. RIBOSOMAL_L21E. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "High-efficiency full-length cDNA cloning."
      Carninci P., Hayashizaki Y.
      Methods Enzymol. 303:19-44(1999) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE.
      Strain: BALB/CImported and C57BL/6JImported.
      Tissue: AmnionImported, BrainImported, LungImported and Small intestineImported.
    2. "Normalization and subtraction of cap-trapper-selected cDNAs to prepare full-length cDNA libraries for rapid discovery of new genes."
      Carninci P., Shibata Y., Hayatsu N., Sugahara Y., Shibata K., Itoh M., Konno H., Okazaki Y., Muramatsu M., Hayashizaki Y.
      Genome Res. 10:1617-1630(2000) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE.
      Strain: BALB/CImported and C57BL/6JImported.
      Tissue: AmnionImported, BrainImported, LungImported and Small intestineImported.
    3. Cited for: NUCLEOTIDE SEQUENCE.
      Strain: BALB/CImported and C57BL/6JImported.
      Tissue: AmnionImported, BrainImported, LungImported and Small intestineImported.
    4. Cited for: NUCLEOTIDE SEQUENCE.
      Strain: C57BL/6JImported.
      Tissue: BrainImported, LungImported and Small intestineImported.
    5. "Functional annotation of a full-length mouse cDNA collection."
      The RIKEN Genome Exploration Research Group Phase II Team and the FANTOM Consortium
      Nature 409:685-690(2001)
      Cited for: NUCLEOTIDE SEQUENCE.
      Strain: BALB/CImported and C57BL/6JImported.
      Tissue: AmnionImported, BrainImported, LungImported and Small intestineImported.
    6. "Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs."
      The FANTOM Consortium and the RIKEN Genome Exploration Research Group Phase I and II Team
      Nature 420:563-573(2002)
      Cited for: NUCLEOTIDE SEQUENCE.
      Strain: BALB/CImported and C57BL/6JImported.
      Tissue: AmnionImported, BrainImported, LungImported and Small intestineImported.
    7. "A comparison of whole-genome shotgun-derived mouse chromosome 16 and the human genome."
      Mural R.J., Adams M.D., Myers E.W., Smith H.O., Miklos G.L., Wides R., Halpern A., Li P.W., Sutton G.G., Nadeau J., Salzberg S.L., Holt R.A., Kodira C.D., Lu F., Chen L., Deng Z., Evangelista C.C., Gan W.
      , Heiman T.J., Li J., Li Z., Merkulov G.V., Milshina N.V., Naik A.K., Qi R., Shue B.C., Wang A., Wang J., Wang X., Yan X., Ye J., Yooseph S., Zhao Q., Zheng L., Zhu S.C., Biddick K., Bolanos R., Delcher A.L., Dew I.M., Fasulo D., Flanigan M.J., Huson D.H., Kravitz S.A., Miller J.R., Mobarry C.M., Reinert K., Remington K.A., Zhang Q., Zheng X.H., Nusskern D.R., Lai Z., Lei Y., Zhong W., Yao A., Guan P., Ji R.R., Gu Z., Wang Z.Y., Zhong F., Xiao C., Chiang C.C., Yandell M., Wortman J.R., Amanatides P.G., Hladun S.L., Pratts E.C., Johnson J.E., Dodson K.L., Woodford K.J., Evans C.A., Gropman B., Rusch D.B., Venter E., Wang M., Smith T.J., Houck J.T., Tompkins D.E., Haynes C., Jacob D., Chin S.H., Allen D.R., Dahlke C.E., Sanders R., Li K., Liu X., Levitsky A.A., Majoros W.H., Chen Q., Xia A.C., Lopez J.R., Donnelly M.T., Newman M.H., Glodek A., Kraft C.L., Nodell M., Ali F., An H.J., Baldwin-Pitts D., Beeson K.Y., Cai S., Carnes M., Carver A., Caulk P.M., Center A., Chen Y.H., Cheng M.L., Coyne M.D., Crowder M., Danaher S., Davenport L.B., Desilets R., Dietz S.M., Doup L., Dullaghan P., Ferriera S., Fosler C.R., Gire H.C., Gluecksmann A., Gocayne J.D., Gray J., Hart B., Haynes J., Hoover J., Howland T., Ibegwam C., Jalali M., Johns D., Kline L., Ma D.S., MacCawley S., Magoon A., Mann F., May D., McIntosh T.C., Mehta S., Moy L., Moy M.C., Murphy B.J., Murphy S.D., Nelson K.A., Nuri Z., Parker K.A., Prudhomme A.C., Puri V.N., Qureshi H., Raley J.C., Reardon M.S., Regier M.A., Rogers Y.H., Romblad D.L., Schutz J., Scott J.L., Scott R., Sitter C.D., Smallwood M., Sprague A.C., Stewart E., Strong R.V., Suh E., Sylvester K., Thomas R., Tint N.N., Tsonis C., Wang G., Wang G., Williams M.S., Williams S.M., Windsor S.M., Wolfe K., Wu M.M., Zaveri J., Chaturvedi K., Gabrielian A.E., Ke Z., Sun J., Subramanian G., Venter J.C., Pfannkoch C.M., Barnstead M., Stephenson L.D.
      Science 296:1661-1671(2002) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE.
      Strain: MixedImported.
    8. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Gerhard D.S., Wagner L., Feingold E.A., Shenmen C.M., Grouse L.H., Schuler G., Klein S.L., Old S., Rasooly R., Good P., Guyer M., Peck A.M., Derge J.G., Lipman D., Collins F.S., Jang W., Sherry S., Feolo M.
      , Misquitta L., Lee E., Rotmistrovsky K., Greenhut S.F., Schaefer C.F., Buetow K., Bonner T.I., Haussler D., Kent J., Kiekhaus M., Furey T., Brent M., Prange C., Schreiber K., Shapiro N., Bhat N.K., Hopkins R.F., Hsie F., Driscoll T., Soares M.B., Casavant T.L., Scheetz T.E., Brown-stein M.J., Usdin T.B., Toshiyuki S., Carninci P., Piao Y., Dudekula D.B., Ko M.S., Kawakami K., Suzuki Y., Sugano S., Gruber C.E., Smith M.R., Simmons B., Moore T., Waterman R., Johnson S.L., Ruan Y., Wei C.L., Mathavan S., Gunaratne P.H., Wu J., Garcia A.M., Hulyk S.W., Fuh E., Yuan Y., Sneed A., Kowis C., Hodgson A., Muzny D.M., McPherson J., Gibbs R.A., Fahey J., Helton E., Ketteman M., Madan A., Rodrigues S., Sanchez A., Whiting M., Madari A., Young A.C., Wetherby K.D., Granite S.J., Kwong P.N., Brinkley C.P., Pearson R.L., Bouffard G.G., Blakesly R.W., Green E.D., Dickson M.C., Rodriguez A.C., Grimwood J., Schmutz J., Myers R.M., Butterfield Y.S., Griffith M., Griffith O.L., Krzywinski M.I., Liao N., Morin R., Morrin R., Palmquist D., Petrescu A.S., Skalska U., Smailus D.E., Stott J.M., Schnerch A., Schein J.E., Jones S.J., Holt R.A., Baross A., Marra M.A., Clifton S., Makowski K.A., Bosak S., Malek J.
      Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
      Strain: C57BL/6JImported and Mix FVB/NImported.
      Tissue: BrainImported, HeartImported, KidneyImported, Mammary glandImported and Mammary tumor. WAP-TGF alpha model. 7 months oldImported.
    9. Cited for: NUCLEOTIDE SEQUENCE.
      Strain: BALB/CImported.
    10. Cited for: NUCLEOTIDE SEQUENCE.
      Strain: C57BL/6JImported.
      Tissue: AmnionImported.
    11. "The Transcriptional Landscape of the Mammalian Genome."
      The FANTOM Consortium, Riken Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group)
      Science 309:1559-1563(2005)
      Cited for: NUCLEOTIDE SEQUENCE.
      Strain: BALB/CImported and C57BL/6JImported.
      Tissue: AmnionImported, BrainImported, LungImported and Small intestineImported.
    12. Cited for: NUCLEOTIDE SEQUENCE.
      Strain: BALB/CImported and C57BL/6JImported.
      Tissue: AmnionImported, BrainImported, LungImported and Small intestineImported.
    13. Mural R.J., Adams M.D., Myers E.W., Smith H.O., Venter J.C.
      Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE.
      Strain: MixedImported.
    14. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: C57BL/6JImported.
    15. Ensembl
      Submitted (FEB-2012) to UniProtKB
      Cited for: IDENTIFICATION.
      Strain: C57BL/6JImported.
    16. Ensembl
      Submitted (MAY-2012) to UniProtKB
      Cited for: IDENTIFICATION.
      Strain: C57BL/6JImported.
    17. Ensembl
      Submitted (JUN-2012) to UniProtKB
      Cited for: IDENTIFICATION.
      Strain: C57BL/6JImported.

    Entry informationi

    Entry nameiQ9CQM8_MOUSE
    AccessioniPrimary (citable) accession number: Q9CQM8
    Entry historyi
    Integrated into UniProtKB/TrEMBL: June 1, 2001
    Last sequence update: June 1, 2001
    Last modified: October 1, 2014
    This is version 119 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3