ID   RM20_MOUSE              Reviewed;         149 AA.
AC   Q9CQL4; Q9D5L3;
DT   05-SEP-2006, integrated into UniProtKB/Swiss-Prot.
DT   01-JUN-2001, sequence version 1.
DT   27-MAR-2024, entry version 155.
DE   RecName: Full=Large ribosomal subunit protein bL20m {ECO:0000305};
DE   AltName: Full=39S ribosomal protein L20, mitochondrial;
DE            Short=L20mt;
DE            Short=MRP-L20;
DE   Flags: Precursor;
GN   Name=Mrpl20;
OS   Mus musculus (Mouse).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC   Murinae; Mus; Mus.
OX   NCBI_TaxID=10090;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA].
RX   PubMed=11279069; DOI=10.1074/jbc.m100432200;
RA   Suzuki T., Terasaki M., Takemoto-Hori C., Hanada T., Ueda T., Wada A.,
RA   Watanabe K.;
RT   "Structural compensation for the deficit of rRNA with proteins in the
RT   mammalian mitochondrial ribosome. Systematic analysis of protein components
RT   of the large ribosomal subunit from mammalian mitochondria.";
RL   J. Biol. Chem. 276:21724-21736(2001).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=C57BL/6J; TISSUE=Stomach, and Testis;
RX   PubMed=16141072; DOI=10.1126/science.1112014;
RA   Carninci P., Kasukawa T., Katayama S., Gough J., Frith M.C., Maeda N.,
RA   Oyama R., Ravasi T., Lenhard B., Wells C., Kodzius R., Shimokawa K.,
RA   Bajic V.B., Brenner S.E., Batalov S., Forrest A.R., Zavolan M., Davis M.J.,
RA   Wilming L.G., Aidinis V., Allen J.E., Ambesi-Impiombato A., Apweiler R.,
RA   Aturaliya R.N., Bailey T.L., Bansal M., Baxter L., Beisel K.W., Bersano T.,
RA   Bono H., Chalk A.M., Chiu K.P., Choudhary V., Christoffels A.,
RA   Clutterbuck D.R., Crowe M.L., Dalla E., Dalrymple B.P., de Bono B.,
RA   Della Gatta G., di Bernardo D., Down T., Engstrom P., Fagiolini M.,
RA   Faulkner G., Fletcher C.F., Fukushima T., Furuno M., Futaki S.,
RA   Gariboldi M., Georgii-Hemming P., Gingeras T.R., Gojobori T., Green R.E.,
RA   Gustincich S., Harbers M., Hayashi Y., Hensch T.K., Hirokawa N., Hill D.,
RA   Huminiecki L., Iacono M., Ikeo K., Iwama A., Ishikawa T., Jakt M.,
RA   Kanapin A., Katoh M., Kawasawa Y., Kelso J., Kitamura H., Kitano H.,
RA   Kollias G., Krishnan S.P., Kruger A., Kummerfeld S.K., Kurochkin I.V.,
RA   Lareau L.F., Lazarevic D., Lipovich L., Liu J., Liuni S., McWilliam S.,
RA   Madan Babu M., Madera M., Marchionni L., Matsuda H., Matsuzawa S., Miki H.,
RA   Mignone F., Miyake S., Morris K., Mottagui-Tabar S., Mulder N., Nakano N.,
RA   Nakauchi H., Ng P., Nilsson R., Nishiguchi S., Nishikawa S., Nori F.,
RA   Ohara O., Okazaki Y., Orlando V., Pang K.C., Pavan W.J., Pavesi G.,
RA   Pesole G., Petrovsky N., Piazza S., Reed J., Reid J.F., Ring B.Z.,
RA   Ringwald M., Rost B., Ruan Y., Salzberg S.L., Sandelin A., Schneider C.,
RA   Schoenbach C., Sekiguchi K., Semple C.A., Seno S., Sessa L., Sheng Y.,
RA   Shibata Y., Shimada H., Shimada K., Silva D., Sinclair B., Sperling S.,
RA   Stupka E., Sugiura K., Sultana R., Takenaka Y., Taki K., Tammoja K.,
RA   Tan S.L., Tang S., Taylor M.S., Tegner J., Teichmann S.A., Ueda H.R.,
RA   van Nimwegen E., Verardo R., Wei C.L., Yagi K., Yamanishi H.,
RA   Zabarovsky E., Zhu S., Zimmer A., Hide W., Bult C., Grimmond S.M.,
RA   Teasdale R.D., Liu E.T., Brusic V., Quackenbush J., Wahlestedt C.,
RA   Mattick J.S., Hume D.A., Kai C., Sasaki D., Tomaru Y., Fukuda S.,
RA   Kanamori-Katayama M., Suzuki M., Aoki J., Arakawa T., Iida J., Imamura K.,
RA   Itoh M., Kato T., Kawaji H., Kawagashira N., Kawashima T., Kojima M.,
RA   Kondo S., Konno H., Nakano K., Ninomiya N., Nishio T., Okada M., Plessy C.,
RA   Shibata K., Shiraki T., Suzuki S., Tagami M., Waki K., Watahiki A.,
RA   Okamura-Oho Y., Suzuki H., Kawai J., Hayashizaki Y.;
RT   "The transcriptional landscape of the mammalian genome.";
RL   Science 309:1559-1563(2005).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=C57BL/6J; TISSUE=Mammary gland;
RX   PubMed=15489334; DOI=10.1101/gr.2596504;
RG   The MGC Project Team;
RT   "The status, quality, and expansion of the NIH full-length cDNA project:
RT   the Mammalian Gene Collection (MGC).";
RL   Genome Res. 14:2121-2127(2004).
RN   [4]
RP   PROTEIN SEQUENCE OF 83-92, AND IDENTIFICATION BY MASS SPECTROMETRY.
RC   STRAIN=OF1; TISSUE=Hippocampus;
RA   Lubec G., Sunyer B., Chen W.-Q.;
RL   Submitted (JAN-2009) to UniProtKB.
RN   [5]
RP   IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RC   TISSUE=Brown adipose tissue, Heart, Kidney, Liver, Spleen, and Testis;
RX   PubMed=21183079; DOI=10.1016/j.cell.2010.12.001;
RA   Huttlin E.L., Jedrychowski M.P., Elias J.E., Goswami T., Rad R.,
RA   Beausoleil S.A., Villen J., Haas W., Sowa M.E., Gygi S.P.;
RT   "A tissue-specific atlas of mouse protein phosphorylation and expression.";
RL   Cell 143:1174-1189(2010).
CC   -!- SUBUNIT: Component of the mitochondrial ribosome large subunit (39S)
CC       which comprises a 16S rRNA and about 50 distinct proteins (By
CC       similarity). Interacts with OXA1L (By similarity).
CC       {ECO:0000250|UniProtKB:Q2TBR2, ECO:0000250|UniProtKB:Q9BYC9}.
CC   -!- SUBCELLULAR LOCATION: Mitochondrion {ECO:0000250|UniProtKB:Q2TBR2}.
CC   -!- SIMILARITY: Belongs to the bacterial ribosomal protein bL20 family.
CC       {ECO:0000305}.
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DR   EMBL; AB049645; BAB40850.1; -; mRNA.
DR   EMBL; AK004053; BAB23143.1; -; mRNA.
DR   EMBL; AK011341; BAB27555.1; -; mRNA.
DR   EMBL; AK015199; BAB29744.1; -; mRNA.
DR   EMBL; AK168665; BAE40517.1; -; mRNA.
DR   EMBL; BC039985; AAH39985.1; -; mRNA.
DR   CCDS; CCDS19041.1; -.
DR   RefSeq; NP_079846.1; NM_025570.2.
DR   RefSeq; XP_006539167.1; XM_006539104.2.
DR   AlphaFoldDB; Q9CQL4; -.
DR   SMR; Q9CQL4; -.
DR   BioGRID; 211482; 2.
DR   ComplexPortal; CPX-5302; 39S mitochondrial large ribosomal subunit.
DR   STRING; 10090.ENSMUSP00000030942; -.
DR   iPTMnet; Q9CQL4; -.
DR   PhosphoSitePlus; Q9CQL4; -.
DR   EPD; Q9CQL4; -.
DR   jPOST; Q9CQL4; -.
DR   MaxQB; Q9CQL4; -.
DR   PaxDb; 10090-ENSMUSP00000030942; -.
DR   PeptideAtlas; Q9CQL4; -.
DR   ProteomicsDB; 300519; -.
DR   Pumba; Q9CQL4; -.
DR   Antibodypedia; 51971; 113 antibodies from 19 providers.
DR   DNASU; 66448; -.
DR   Ensembl; ENSMUST00000030942.13; ENSMUSP00000030942.6; ENSMUSG00000029066.13.
DR   Ensembl; ENSMUST00000137487.9; ENSMUSP00000139122.2; ENSMUSG00000029066.13.
DR   GeneID; 66448; -.
DR   KEGG; mmu:66448; -.
DR   UCSC; uc008weu.1; mouse.
DR   AGR; MGI:2137221; -.
DR   CTD; 55052; -.
DR   MGI; MGI:2137221; Mrpl20.
DR   VEuPathDB; HostDB:ENSMUSG00000029066; -.
DR   eggNOG; KOG4707; Eukaryota.
DR   GeneTree; ENSGT00390000015823; -.
DR   HOGENOM; CLU_123265_1_1_1; -.
DR   InParanoid; Q9CQL4; -.
DR   OMA; GRRKNVW; -.
DR   OrthoDB; 5475236at2759; -.
DR   PhylomeDB; Q9CQL4; -.
DR   TreeFam; TF324702; -.
DR   Reactome; R-MMU-5389840; Mitochondrial translation elongation.
DR   Reactome; R-MMU-5419276; Mitochondrial translation termination.
DR   BioGRID-ORCS; 66448; 30 hits in 78 CRISPR screens.
DR   ChiTaRS; Mrpl20; mouse.
DR   PRO; PR:Q9CQL4; -.
DR   Proteomes; UP000000589; Chromosome 4.
DR   RNAct; Q9CQL4; Protein.
DR   Bgee; ENSMUSG00000029066; Expressed in gastrula and 301 other cell types or tissues.
DR   ExpressionAtlas; Q9CQL4; baseline and differential.
DR   GO; GO:0005743; C:mitochondrial inner membrane; NAS:ComplexPortal.
DR   GO; GO:0005762; C:mitochondrial large ribosomal subunit; ISS:UniProtKB.
DR   GO; GO:0005761; C:mitochondrial ribosome; ISS:UniProtKB.
DR   GO; GO:0005739; C:mitochondrion; HDA:MGI.
DR   GO; GO:0019843; F:rRNA binding; IEA:InterPro.
DR   GO; GO:0003735; F:structural constituent of ribosome; ISO:MGI.
DR   GO; GO:0032543; P:mitochondrial translation; NAS:ComplexPortal.
DR   GO; GO:0006412; P:translation; ISO:MGI.
DR   CDD; cd07026; Ribosomal_L20; 1.
DR   Gene3D; 6.10.160.10; -; 1.
DR   Gene3D; 1.10.1900.20; Ribosomal protein L20; 1.
DR   InterPro; IPR005813; Ribosomal_bL20.
DR   InterPro; IPR035566; Ribosomal_protein_bL20_C.
DR   NCBIfam; TIGR01032; rplT_bact; 1.
DR   PANTHER; PTHR10986; 39S RIBOSOMAL PROTEIN L20; 1.
DR   PANTHER; PTHR10986:SF26; 39S RIBOSOMAL PROTEIN L20, MITOCHONDRIAL; 1.
DR   Pfam; PF00453; Ribosomal_L20; 1.
DR   PRINTS; PR00062; RIBOSOMALL20.
DR   SUPFAM; SSF74731; Ribosomal protein L20; 1.
DR   Genevisible; Q9CQL4; MM.
PE   1: Evidence at protein level;
KW   Direct protein sequencing; Mitochondrion; Reference proteome;
KW   Ribonucleoprotein; Ribosomal protein; Transit peptide.
FT   TRANSIT         1..9
FT                   /note="Mitochondrion"
FT                   /evidence="ECO:0000250|UniProtKB:Q2TBR2"
FT   CHAIN           10..149
FT                   /note="Large ribosomal subunit protein bL20m"
FT                   /id="PRO_0000248280"
FT   CONFLICT        62
FT                   /note="R -> L (in Ref. 2; BAB29744)"
FT                   /evidence="ECO:0000305"
SQ   SEQUENCE   149 AA;  17595 MW;  7B86D8C568B633AE CRC64;
     MVFLTTRLWL RNRLTDRYWR VQEVLKHAQH FRGRKNRCYR LAVRAVTRAF VKCTKARRLK
     KRNLRTLWIN RITAASQEHG LKYPAFIVNL IKCQVELNRK VLVDLAIYEP KTFKSLAALA
     KRRQQEGFAA ALGDGKEPEG IFSRVVQYH
//