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Protein

39S ribosomal protein L20, mitochondrial

Gene

Mrpl20

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

  1. poly(A) RNA binding Source: MGI
  2. rRNA binding Source: InterPro
  3. structural constituent of ribosome Source: MGI

GO - Biological processi

  1. translation Source: MGI
Complete GO annotation...

Keywords - Molecular functioni

Ribonucleoprotein, Ribosomal protein

Enzyme and pathway databases

ReactomeiREACT_270125. Mitochondrial translation elongation.
REACT_270158. Mitochondrial translation termination.
REACT_271096. Mitochondrial translation initiation.

Names & Taxonomyi

Protein namesi
Recommended name:
39S ribosomal protein L20, mitochondrial
Short name:
L20mt
Short name:
MRP-L20
Gene namesi
Name:Mrpl20
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
ProteomesiUP000000589: Chromosome 4

Organism-specific databases

MGIiMGI:2137221. Mrpl20.

Subcellular locationi

Mitochondrion 1 Publication

GO - Cellular componenti

  1. mitochondrial large ribosomal subunit Source: MGI
  2. mitochondrial ribosome Source: UniProtKB
  3. mitochondrion Source: MGI
Complete GO annotation...

Keywords - Cellular componenti

Mitochondrion

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transit peptidei1 – 4545MitochondrionSequence AnalysisAdd
BLAST
Chaini46 – 14910439S ribosomal protein L20, mitochondrialPRO_0000248280Add
BLAST

Proteomic databases

MaxQBiQ9CQL4.
PaxDbiQ9CQL4.
PRIDEiQ9CQL4.

PTM databases

PhosphoSiteiQ9CQL4.

Expressioni

Gene expression databases

BgeeiQ9CQL4.
CleanExiMM_MRPL20.
ExpressionAtlasiQ9CQL4. baseline and differential.
GenevestigatoriQ9CQL4.

Interactioni

Subunit structurei

Interacts with OXA1L.By similarity

Structurei

3D structure databases

ProteinModelPortaliQ9CQL4.
SMRiQ9CQL4. Positions 10-124.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the ribosomal protein L20P family.Curated

Keywords - Domaini

Transit peptide

Phylogenomic databases

eggNOGiCOG0292.
GeneTreeiENSGT00390000015823.
HOGENOMiHOG000035046.
HOVERGENiHBG058971.
InParanoidiQ9CQL4.
KOiK02887.
OMAiGRRKNVW.
OrthoDBiEOG7PZS00.
PhylomeDBiQ9CQL4.
TreeFamiTF324702.

Family and domain databases

InterProiIPR005813. Ribosomal_L20.
[Graphical view]
PANTHERiPTHR10986. PTHR10986. 1 hit.
PfamiPF00453. Ribosomal_L20. 1 hit.
[Graphical view]
PRINTSiPR00062. RIBOSOMALL20.
TIGRFAMsiTIGR01032. rplT_bact. 1 hit.

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q9CQL4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MVFLTTRLWL RNRLTDRYWR VQEVLKHAQH FRGRKNRCYR LAVRAVTRAF
60 70 80 90 100
VKCTKARRLK KRNLRTLWIN RITAASQEHG LKYPAFIVNL IKCQVELNRK
110 120 130 140
VLVDLAIYEP KTFKSLAALA KRRQQEGFAA ALGDGKEPEG IFSRVVQYH
Length:149
Mass (Da):17,595
Last modified:June 1, 2001 - v1
Checksum:i7B86D8C568B633AE
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sequence conflicti62 – 621R → L in BAB29744 (PubMed:16141072).Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB049645 mRNA. Translation: BAB40850.1.
AK004053 mRNA. Translation: BAB23143.1.
AK011341 mRNA. Translation: BAB27555.1.
AK015199 mRNA. Translation: BAB29744.1.
AK168665 mRNA. Translation: BAE40517.1.
BC039985 mRNA. Translation: AAH39985.1.
CCDSiCCDS19041.1.
RefSeqiNP_079846.1. NM_025570.2.
XP_006539167.1. XM_006539104.1.
UniGeneiMm.23825.

Genome annotation databases

EnsembliENSMUST00000030942; ENSMUSP00000030942; ENSMUSG00000029066.
ENSMUST00000137487; ENSMUSP00000139122; ENSMUSG00000029066.
GeneIDi66448.
KEGGimmu:66448.
UCSCiuc008weu.1. mouse.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB049645 mRNA. Translation: BAB40850.1.
AK004053 mRNA. Translation: BAB23143.1.
AK011341 mRNA. Translation: BAB27555.1.
AK015199 mRNA. Translation: BAB29744.1.
AK168665 mRNA. Translation: BAE40517.1.
BC039985 mRNA. Translation: AAH39985.1.
CCDSiCCDS19041.1.
RefSeqiNP_079846.1. NM_025570.2.
XP_006539167.1. XM_006539104.1.
UniGeneiMm.23825.

3D structure databases

ProteinModelPortaliQ9CQL4.
SMRiQ9CQL4. Positions 10-124.
ModBaseiSearch...
MobiDBiSearch...

PTM databases

PhosphoSiteiQ9CQL4.

Proteomic databases

MaxQBiQ9CQL4.
PaxDbiQ9CQL4.
PRIDEiQ9CQL4.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000030942; ENSMUSP00000030942; ENSMUSG00000029066.
ENSMUST00000137487; ENSMUSP00000139122; ENSMUSG00000029066.
GeneIDi66448.
KEGGimmu:66448.
UCSCiuc008weu.1. mouse.

Organism-specific databases

CTDi55052.
MGIiMGI:2137221. Mrpl20.

Phylogenomic databases

eggNOGiCOG0292.
GeneTreeiENSGT00390000015823.
HOGENOMiHOG000035046.
HOVERGENiHBG058971.
InParanoidiQ9CQL4.
KOiK02887.
OMAiGRRKNVW.
OrthoDBiEOG7PZS00.
PhylomeDBiQ9CQL4.
TreeFamiTF324702.

Enzyme and pathway databases

ReactomeiREACT_270125. Mitochondrial translation elongation.
REACT_270158. Mitochondrial translation termination.
REACT_271096. Mitochondrial translation initiation.

Miscellaneous databases

NextBioi321725.
PROiQ9CQL4.
SOURCEiSearch...

Gene expression databases

BgeeiQ9CQL4.
CleanExiMM_MRPL20.
ExpressionAtlasiQ9CQL4. baseline and differential.
GenevestigatoriQ9CQL4.

Family and domain databases

InterProiIPR005813. Ribosomal_L20.
[Graphical view]
PANTHERiPTHR10986. PTHR10986. 1 hit.
PfamiPF00453. Ribosomal_L20. 1 hit.
[Graphical view]
PRINTSiPR00062. RIBOSOMALL20.
TIGRFAMsiTIGR01032. rplT_bact. 1 hit.
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. "Structural compensation for the deficit of rRNA with proteins in the mammalian mitochondrial ribosome. Systematic analysis of protein components of the large ribosomal subunit from mammalian mitochondria."
    Suzuki T., Terasaki M., Takemoto-Hori C., Hanada T., Ueda T., Wada A., Watanabe K.
    J. Biol. Chem. 276:21724-21736(2001) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [MRNA], SUBCELLULAR LOCATION.
  2. "The transcriptional landscape of the mammalian genome."
    Carninci P., Kasukawa T., Katayama S., Gough J., Frith M.C., Maeda N., Oyama R., Ravasi T., Lenhard B., Wells C., Kodzius R., Shimokawa K., Bajic V.B., Brenner S.E., Batalov S., Forrest A.R., Zavolan M., Davis M.J.
    , Wilming L.G., Aidinis V., Allen J.E., Ambesi-Impiombato A., Apweiler R., Aturaliya R.N., Bailey T.L., Bansal M., Baxter L., Beisel K.W., Bersano T., Bono H., Chalk A.M., Chiu K.P., Choudhary V., Christoffels A., Clutterbuck D.R., Crowe M.L., Dalla E., Dalrymple B.P., de Bono B., Della Gatta G., di Bernardo D., Down T., Engstrom P., Fagiolini M., Faulkner G., Fletcher C.F., Fukushima T., Furuno M., Futaki S., Gariboldi M., Georgii-Hemming P., Gingeras T.R., Gojobori T., Green R.E., Gustincich S., Harbers M., Hayashi Y., Hensch T.K., Hirokawa N., Hill D., Huminiecki L., Iacono M., Ikeo K., Iwama A., Ishikawa T., Jakt M., Kanapin A., Katoh M., Kawasawa Y., Kelso J., Kitamura H., Kitano H., Kollias G., Krishnan S.P., Kruger A., Kummerfeld S.K., Kurochkin I.V., Lareau L.F., Lazarevic D., Lipovich L., Liu J., Liuni S., McWilliam S., Madan Babu M., Madera M., Marchionni L., Matsuda H., Matsuzawa S., Miki H., Mignone F., Miyake S., Morris K., Mottagui-Tabar S., Mulder N., Nakano N., Nakauchi H., Ng P., Nilsson R., Nishiguchi S., Nishikawa S., Nori F., Ohara O., Okazaki Y., Orlando V., Pang K.C., Pavan W.J., Pavesi G., Pesole G., Petrovsky N., Piazza S., Reed J., Reid J.F., Ring B.Z., Ringwald M., Rost B., Ruan Y., Salzberg S.L., Sandelin A., Schneider C., Schoenbach C., Sekiguchi K., Semple C.A., Seno S., Sessa L., Sheng Y., Shibata Y., Shimada H., Shimada K., Silva D., Sinclair B., Sperling S., Stupka E., Sugiura K., Sultana R., Takenaka Y., Taki K., Tammoja K., Tan S.L., Tang S., Taylor M.S., Tegner J., Teichmann S.A., Ueda H.R., van Nimwegen E., Verardo R., Wei C.L., Yagi K., Yamanishi H., Zabarovsky E., Zhu S., Zimmer A., Hide W., Bult C., Grimmond S.M., Teasdale R.D., Liu E.T., Brusic V., Quackenbush J., Wahlestedt C., Mattick J.S., Hume D.A., Kai C., Sasaki D., Tomaru Y., Fukuda S., Kanamori-Katayama M., Suzuki M., Aoki J., Arakawa T., Iida J., Imamura K., Itoh M., Kato T., Kawaji H., Kawagashira N., Kawashima T., Kojima M., Kondo S., Konno H., Nakano K., Ninomiya N., Nishio T., Okada M., Plessy C., Shibata K., Shiraki T., Suzuki S., Tagami M., Waki K., Watahiki A., Okamura-Oho Y., Suzuki H., Kawai J., Hayashizaki Y.
    Science 309:1559-1563(2005) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Strain: C57BL/6J.
    Tissue: Stomach and Testis.
  3. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Strain: C57BL/6J.
    Tissue: Mammary gland.
  4. Lubec G., Sunyer B., Chen W.-Q.
    Submitted (JAN-2009) to UniProtKB
    Cited for: PROTEIN SEQUENCE OF 83-92, IDENTIFICATION BY MASS SPECTROMETRY.
    Strain: OF1.
    Tissue: Hippocampus.

Entry informationi

Entry nameiRM20_MOUSE
AccessioniPrimary (citable) accession number: Q9CQL4
Secondary accession number(s): Q9D5L3
Entry historyi
Integrated into UniProtKB/Swiss-Prot: September 5, 2006
Last sequence update: June 1, 2001
Last modified: February 4, 2015
This is version 101 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Direct protein sequencing, Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
  2. Ribosomal proteins
    Ribosomal proteins families and list of entries
  3. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.