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Protein

Zinc finger HIT domain-containing protein 3

Gene

Znhit3

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Zinc fingeri11 – 42HIT-typePROSITE-ProRule annotationAdd BLAST32

GO - Molecular functioni

Keywordsi

LigandMetal-binding, Zinc

Names & Taxonomyi

Protein namesi
Recommended name:
Zinc finger HIT domain-containing protein 3
Alternative name(s):
Thyroid hormone receptor interactor 3
Thyroid receptor-interacting protein 3
Short name:
TR-interacting protein 3
Short name:
TRIP-3
Gene namesi
Name:Znhit3
Synonyms:Trip3
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 11

Organism-specific databases

MGIiMGI:3051596. Znhit3.

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001735521 – 151Zinc finger HIT domain-containing protein 3Add BLAST151

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei76PhosphoserineCombined sources1

Keywords - PTMi

Phosphoprotein

Proteomic databases

EPDiQ9CQK1.
MaxQBiQ9CQK1.
PaxDbiQ9CQK1.
PeptideAtlasiQ9CQK1.
PRIDEiQ9CQK1.

PTM databases

iPTMnetiQ9CQK1.
PhosphoSitePlusiQ9CQK1.

Expressioni

Gene expression databases

BgeeiENSMUSG00000020526.
CleanExiMM_ZNHIT3.
GenevisibleiQ9CQK1. MM.

Interactioni

Subunit structurei

Thyroid receptor interacting proteins (TRIPs) specifically interact with the ligand binding domain of the thyroid receptor (TR). Requires the presence of thyroid hormone for its interaction (By similarity).By similarity

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000099484.

Structurei

3D structure databases

ProteinModelPortaliQ9CQK1.
SMRiQ9CQK1.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Zinc finger

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Zinc fingeri11 – 42HIT-typePROSITE-ProRule annotationAdd BLAST32

Keywords - Domaini

Zinc-finger

Phylogenomic databases

eggNOGiKOG2857. Eukaryota.
ENOG41123YY. LUCA.
GeneTreeiENSGT00390000010822.
HOGENOMiHOG000230732.
HOVERGENiHBG055775.
InParanoidiQ9CQK1.
OMAiKIHKETP.
OrthoDBiEOG091G0VWN.
PhylomeDBiQ9CQK1.
TreeFamiTF324673.

Family and domain databases

InterProiView protein in InterPro
IPR007529. Znf_HIT.
PfamiView protein in Pfam
PF04438. zf-HIT. 1 hit.
PROSITEiView protein in PROSITE
PS51083. ZF_HIT. 1 hit.

Sequencei

Sequence statusi: Complete.

Q9CQK1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MASLNCRTAV CVVCLEKPKY RCPTCRVPYC SVPCFQKHKE QCSSEARPVE
60 70 80 90 100
KRRAGPPVRS EESKDDDSSV ADFLNSDEEE DRVSLQNLKN LGESETLRSL
110 120 130 140 150
LLNPHLRQLM ISLDQGDNKA KLMRACMQEP LFVEFADCCL GIVEPSQKRD

S
Length:151
Mass (Da):17,068
Last modified:June 1, 2001 - v1
Checksum:i8047204E2072EFE9
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK014350 mRNA. Translation: BAB29291.1.
AK002888 mRNA. Translation: BAB22434.1.
AK003721 mRNA. Translation: BAB22958.1.
AK004259 mRNA. Translation: BAB23239.1.
AL645623 Genomic DNA. Translation: CAI25491.1.
CCDSiCCDS25189.1.
RefSeqiNP_001005223.1. NM_001005223.2.
UniGeneiMm.379733.

Genome annotation databases

EnsembliENSMUST00000103195; ENSMUSP00000099484; ENSMUSG00000020526.
GeneIDi448850.
KEGGimmu:448850.
UCSCiuc007kre.1. mouse.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK014350 mRNA. Translation: BAB29291.1.
AK002888 mRNA. Translation: BAB22434.1.
AK003721 mRNA. Translation: BAB22958.1.
AK004259 mRNA. Translation: BAB23239.1.
AL645623 Genomic DNA. Translation: CAI25491.1.
CCDSiCCDS25189.1.
RefSeqiNP_001005223.1. NM_001005223.2.
UniGeneiMm.379733.

3D structure databases

ProteinModelPortaliQ9CQK1.
SMRiQ9CQK1.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000099484.

PTM databases

iPTMnetiQ9CQK1.
PhosphoSitePlusiQ9CQK1.

Proteomic databases

EPDiQ9CQK1.
MaxQBiQ9CQK1.
PaxDbiQ9CQK1.
PeptideAtlasiQ9CQK1.
PRIDEiQ9CQK1.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000103195; ENSMUSP00000099484; ENSMUSG00000020526.
GeneIDi448850.
KEGGimmu:448850.
UCSCiuc007kre.1. mouse.

Organism-specific databases

CTDi9326.
MGIiMGI:3051596. Znhit3.

Phylogenomic databases

eggNOGiKOG2857. Eukaryota.
ENOG41123YY. LUCA.
GeneTreeiENSGT00390000010822.
HOGENOMiHOG000230732.
HOVERGENiHBG055775.
InParanoidiQ9CQK1.
OMAiKIHKETP.
OrthoDBiEOG091G0VWN.
PhylomeDBiQ9CQK1.
TreeFamiTF324673.

Miscellaneous databases

ChiTaRSiZnhit3. mouse.
PROiPR:Q9CQK1.
SOURCEiSearch...

Gene expression databases

BgeeiENSMUSG00000020526.
CleanExiMM_ZNHIT3.
GenevisibleiQ9CQK1. MM.

Family and domain databases

InterProiView protein in InterPro
IPR007529. Znf_HIT.
PfamiView protein in Pfam
PF04438. zf-HIT. 1 hit.
PROSITEiView protein in PROSITE
PS51083. ZF_HIT. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiZNHI3_MOUSE
AccessioniPrimary (citable) accession number: Q9CQK1
Entry historyiIntegrated into UniProtKB/Swiss-Prot: April 12, 2005
Last sequence update: June 1, 2001
Last modified: March 15, 2017
This is version 88 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.