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Protein
Submitted name:

MCG1040641, isoform CRA_a

Gene

Sftpa1

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at protein leveli

Functioni

GO - Biological processi

Complete GO annotation...

Enzyme and pathway databases

ReactomeiR-MMU-166016. Toll Like Receptor 4 (TLR4) Cascade.
R-MMU-391160. Signal regulatory protein (SIRP) family interactions.
R-MMU-5683826. Surfactant metabolism.
R-MMU-5686938. Regulation of TLR by endogenous ligand.

Names & Taxonomyi

Protein namesi
Submitted name:
MCG1040641, isoform CRA_aImported
Submitted name:
Pulmonary surfactant-associated protein AImported
Gene namesi
Name:Sftpa1Imported
ORF Names:mCG_1040641Imported
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 14

Organism-specific databases

MGIiMGI:109518. Sftpa1.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 17Sequence analysisAdd BLAST17
ChainiPRO_500878551918 – 248Sequence analysisAdd BLAST231

Keywords - PTMi

Disulfide bondSAAS annotation

Expressioni

Gene expression databases

BgeeiENSMUSG00000021789.

Interactioni

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000022314.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini134 – 247C-type lectinInterPro annotationAdd BLAST114

Keywords - Domaini

SignalSequence analysis

Phylogenomic databases

eggNOGiKOG4297. Eukaryota.
ENOG410XPJ1. LUCA.
GeneTreeiENSGT00700000104102.
HOVERGENiHBG108270.
KOiK10067.
OMAiTPGDFHY.
OrthoDBiEOG091G0PU5.
TreeFamiTF330481.

Family and domain databases

Gene3Di3.10.100.10. 1 hit.
InterProiIPR001304. C-type_lectin-like.
IPR016186. C-type_lectin-like/link.
IPR018378. C-type_lectin_CS.
IPR016187. CTDL_fold.
[Graphical view]
PfamiPF00059. Lectin_C. 1 hit.
[Graphical view]
SMARTiSM00034. CLECT. 1 hit.
[Graphical view]
SUPFAMiSSF56436. SSF56436. 1 hit.
PROSITEiPS00615. C_TYPE_LECTIN_1. 1 hit.
PS50041. C_TYPE_LECTIN_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q9CQI1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSLGSLAFTL FLTVVAGIKC NGTEVCAGSP GIPGTPGNHG LPGRDGRDGI
60 70 80 90 100
KGDPGPPGPM GPPGGMPGLP GRDGLPGAPG APGEHGDKGE PGERGLPGFP
110 120 130 140 150
AYLDEELQTA LYEIKHQILQ TMGVLSLQGS MLSVGDKVFS TNGQSVNFDT
160 170 180 190 200
IREMCTRAGG HIAAPRNPEE NEAIASITKK YNTYPYLGVI EGQTPGDFHY
210 220 230 240
LDGASVNYTN WYPGEPRGRG KEKCVEMYTD GKWNDKGCLQ YRLAICEF
Length:248
Mass (Da):26,183
Last modified:June 1, 2001 - v1
Checksum:i8A5670CFAD3EB9B6
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC124400 Genomic DNA. No translation available.
AK004620 mRNA. Translation: BAB23416.1.
AK004788 mRNA. Translation: BAB23565.1.
AK011333 mRNA. Translation: BAB27551.1.
CH466573 Genomic DNA. Translation: EDL24919.1.
CH466573 Genomic DNA. Translation: EDL24922.1.
RefSeqiNP_075623.2. NM_023134.4.
UniGeneiMm.46062.

Genome annotation databases

EnsembliENSMUST00000022314; ENSMUSP00000022314; ENSMUSG00000021789.
ENSMUST00000170719; ENSMUSP00000129696; ENSMUSG00000021789.
GeneIDi20387.
KEGGimmu:20387.
UCSCiuc007tcn.1. mouse.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC124400 Genomic DNA. No translation available.
AK004620 mRNA. Translation: BAB23416.1.
AK004788 mRNA. Translation: BAB23565.1.
AK011333 mRNA. Translation: BAB27551.1.
CH466573 Genomic DNA. Translation: EDL24919.1.
CH466573 Genomic DNA. Translation: EDL24922.1.
RefSeqiNP_075623.2. NM_023134.4.
UniGeneiMm.46062.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000022314.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000022314; ENSMUSP00000022314; ENSMUSG00000021789.
ENSMUST00000170719; ENSMUSP00000129696; ENSMUSG00000021789.
GeneIDi20387.
KEGGimmu:20387.
UCSCiuc007tcn.1. mouse.

Organism-specific databases

CTDi653509.
MGIiMGI:109518. Sftpa1.

Phylogenomic databases

eggNOGiKOG4297. Eukaryota.
ENOG410XPJ1. LUCA.
GeneTreeiENSGT00700000104102.
HOVERGENiHBG108270.
KOiK10067.
OMAiTPGDFHY.
OrthoDBiEOG091G0PU5.
TreeFamiTF330481.

Enzyme and pathway databases

ReactomeiR-MMU-166016. Toll Like Receptor 4 (TLR4) Cascade.
R-MMU-391160. Signal regulatory protein (SIRP) family interactions.
R-MMU-5683826. Surfactant metabolism.
R-MMU-5686938. Regulation of TLR by endogenous ligand.

Miscellaneous databases

SOURCEiSearch...

Gene expression databases

BgeeiENSMUSG00000021789.

Family and domain databases

Gene3Di3.10.100.10. 1 hit.
InterProiIPR001304. C-type_lectin-like.
IPR016186. C-type_lectin-like/link.
IPR018378. C-type_lectin_CS.
IPR016187. CTDL_fold.
[Graphical view]
PfamiPF00059. Lectin_C. 1 hit.
[Graphical view]
SMARTiSM00034. CLECT. 1 hit.
[Graphical view]
SUPFAMiSSF56436. SSF56436. 1 hit.
PROSITEiPS00615. C_TYPE_LECTIN_1. 1 hit.
PS50041. C_TYPE_LECTIN_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiQ9CQI1_MOUSE
AccessioniPrimary (citable) accession number: Q9CQI1
Entry historyi
Integrated into UniProtKB/TrEMBL: June 1, 2001
Last sequence update: June 1, 2001
Last modified: November 30, 2016
This is version 130 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.