Q9CQI1 (Q9CQI1_MOUSE) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
MCG1040641, isoform CRA_a EMBL EDL24919.1

Submitted name:
Pulmonary surfactant-associated protein A Ensembl ENSMUSP00000129696 Ensembl ENSMUSP00000022314

Gene names

Name:	Sftpa1 Ensembl ENSMUSP00000129696 MGI 109518 Ensembl ENSMUSP00000022314
ORF Names:	mCG_1040641 EMBL EDL24919.1

Organism

Mus musculus (Mouse) [Reference proteome]

Taxonomic identifier

10090 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Euarchontoglires › Glires › Rodentia › Sciurognathi › Muroidea › Muridae › Murinae › Mus › Mus

Protein attributes

Sequence length	248 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level

General annotation (Comments)

Sequence similarities

Contains 1 C-type lectin domain. SAAS SAAS018378

Ontologies

Keywords
Domain	Collagen SAAS SAAS018378
Ligand	Calcium SAAS SAAS018378 Lectin SAAS SAAS018378
PTM	Disulfide bond SAAS SAAS018378
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	cellular response to mechanical stimulus Inferred from electronic annotation. Source: Compara cellular response to nitric oxide Inferred from electronic annotation. Source: Compara circadian rhythm Inferred from electronic annotation. Source: Compara positive regulation of phagocytosis Inferred from electronic annotation. Source: Compara response to epidermal growth factor stimulus Inferred from electronic annotation. Source: Compara response to glucocorticoid stimulus Inferred from electronic annotation. Source: Compara response to hyperoxia Inferred from electronic annotation. Source: Compara response to hypoxia Inferred from electronic annotation. Source: Compara response to interleukin-6 Inferred from electronic annotation. Source: Compara response to lipopolysaccharide Inferred from electronic annotation. Source: Compara response to retinoic acid Inferred from electronic annotation. Source: Compara response to vitamin A Inferred from electronic annotation. Source: Compara
Cellular_component	collagen Inferred from electronic annotation. Source: UniProtKB-KW cytoplasmic vesicle Inferred from electronic annotation. Source: Compara extracellular space Inferred from electronic annotation. Source: Compara multivesicular body Inferred from electronic annotation. Source: Compara rough endoplasmic reticulum Inferred from electronic annotation. Source: Compara
Molecular_function	bacterial cell surface binding Inferred from electronic annotation. Source: Compara carbohydrate binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q9CQI1 [UniParc]. Last modified June 1, 2001. Version 1. Checksum: 8A5670CFAD3EB9B6	FASTA	248	26,183
	10 20 30 40 50 60 MSLGSLAFTL FLTVVAGIKC NGTEVCAGSP GIPGTPGNHG LPGRDGRDGI KGDPGPPGPM 70 80 90 100 110 120 GPPGGMPGLP GRDGLPGAPG APGEHGDKGE PGERGLPGFP AYLDEELQTA LYEIKHQILQ 130 140 150 160 170 180 TMGVLSLQGS MLSVGDKVFS TNGQSVNFDT IREMCTRAGG HIAAPRNPEE NEAIASITKK 190 200 210 220 230 240 YNTYPYLGVI EGQTPGDFHY LDGASVNYTN WYPGEPRGRG KEKCVEMYTD GKWNDKGCLQ YRLAICEF

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"High-efficiency full-length cDNA cloning." Carninci P., Hayashizaki Y. Methods Enzymol. 303:19-44(1999) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE. Strain: C57BL/6J EMBL BAB27551.1. Tissue: Lung EMBL BAB23416.1 and Whole body EMBL BAB27551.1.
[2]	"Normalization and subtraction of cap-trapper-selected cDNAs to prepare full-length cDNA libraries for rapid discovery of new genes." Carninci P., Shibata Y., Hayatsu N., Sugahara Y., Shibata K., Itoh M., Konno H., Okazaki Y., Muramatsu M., Hayashizaki Y. Genome Res. 10:1617-1630(2000) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE. Strain: C57BL/6J EMBL BAB27551.1. Tissue: Lung EMBL BAB23416.1 and Whole body EMBL BAB27551.1.
[3]	"RIKEN integrated sequence analysis (RISA) system--384-format sequencing pipeline with 384 multicapillary sequencer." Shibata K., Itoh M., Aizawa K., Nagaoka S., Sasaki N., Carninci P., Konno H., Akiyama J., Nishi K., Kitsunai T., Tashiro H., Itoh M., Sumi N., Ishii Y., Nakamura S., Hazama M., Nishine T., Harada A. , Yamamoto R., Matsumoto H., Sakaguchi S., Ikegami T., Kashiwagi K., Fujiwake S., Inoue K., Togawa Y., Izawa M., Ohara E., Watahiki M., Yoneda Y., Ishikawa T., Ozawa K., Tanaka T., Matsuura S., Kawai J., Okazaki Y., Muramatsu M., Inoue Y., Kira A., Hayashizaki Y. Genome Res. 10:1757-1771(2000) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE. Strain: C57BL/6J EMBL BAB27551.1. Tissue: Lung EMBL BAB23416.1 and Whole body EMBL BAB27551.1.
[4]	Adachi J., Aizawa K., Akahira S., Akimura T., Arai A., Aono H., Arakawa T., Bono H., Carninci P., Fukuda S., Fukunishi Y., Furuno M., Hanagaki T., Hara A., Hayatsu N., Hiramoto K., Hiraoka T., Hori F. , Imotani K., Ishii Y., Itoh M., Izawa M., Kasukawa T., Kato H., Kawai J., Kojima Y., Konno H., Kouda M., Koya S., Kurihara C., Matsuyama T., Miyazaki A., Nishi K., Nomura K., Numazaki R., Ohno M., Okazaki Y., Okido T., Owa C., Saito H., Saito R., Sakai C., Sakai K., Sano H., Sasaki D., Shibata K., Shibata Y., Shinagawa A., Shiraki T., Sogabe Y., Suzuki H., Tagami M., Tagawa A., Takahashi F., Tanaka T., Tejima Y., Toya T., Yamamura T., Yasunishi A., Yoshida K., Yoshino M., Muramatsu M., Hayashizaki Y. Submitted (JUL-2000) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE. Strain: C57BL/6J EMBL BAB27551.1. Tissue: Lung EMBL BAB23416.1 and Whole body EMBL BAB27551.1.
[5]	"Functional annotation of a full-length mouse cDNA collection." The RIKEN Genome Exploration Research Group Phase II Team and the FANTOM Consortium Nature 409:685-690(2001) Cited for: NUCLEOTIDE SEQUENCE. Strain: C57BL/6J EMBL BAB27551.1. Tissue: Lung EMBL BAB23416.1 and Whole body EMBL BAB27551.1.
[6]	"Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs." The FANTOM Consortium and the RIKEN Genome Exploration Research Group Phase I and II Team Nature 420:563-573(2002) Cited for: NUCLEOTIDE SEQUENCE. Strain: C57BL/6J EMBL BAB27551.1. Tissue: Lung EMBL BAB23416.1 and Whole body EMBL BAB27551.1.
[7]	"A comparison of whole-genome shotgun-derived mouse chromosome 16 and the human genome." Mural R.J., Adams M.D., Myers E.W., Smith H.O., Miklos G.L., Wides R., Halpern A., Li P.W., Sutton G.G., Nadeau J., Salzberg S.L., Holt R.A., Kodira C.D., Lu F., Chen L., Deng Z., Evangelista C.C., Gan W. , Heiman T.J., Li J., Li Z., Merkulov G.V., Milshina N.V., Naik A.K., Qi R., Shue B.C., Wang A., Wang J., Wang X., Yan X., Ye J., Yooseph S., Zhao Q., Zheng L., Zhu S.C., Biddick K., Bolanos R., Delcher A.L., Dew I.M., Fasulo D., Flanigan M.J., Huson D.H., Kravitz S.A., Miller J.R., Mobarry C.M., Reinert K., Remington K.A., Zhang Q., Zheng X.H., Nusskern D.R., Lai Z., Lei Y., Zhong W., Yao A., Guan P., Ji R.R., Gu Z., Wang Z.Y., Zhong F., Xiao C., Chiang C.C., Yandell M., Wortman J.R., Amanatides P.G., Hladun S.L., Pratts E.C., Johnson J.E., Dodson K.L., Woodford K.J., Evans C.A., Gropman B., Rusch D.B., Venter E., Wang M., Smith T.J., Houck J.T., Tompkins D.E., Haynes C., Jacob D., Chin S.H., Allen D.R., Dahlke C.E., Sanders R., Li K., Liu X., Levitsky A.A., Majoros W.H., Chen Q., Xia A.C., Lopez J.R., Donnelly M.T., Newman M.H., Glodek A., Kraft C.L., Nodell M., Ali F., An H.J., Baldwin-Pitts D., Beeson K.Y., Cai S., Carnes M., Carver A., Caulk P.M., Center A., Chen Y.H., Cheng M.L., Coyne M.D., Crowder M., Danaher S., Davenport L.B., Desilets R., Dietz S.M., Doup L., Dullaghan P., Ferriera S., Fosler C.R., Gire H.C., Gluecksmann A., Gocayne J.D., Gray J., Hart B., Haynes J., Hoover J., Howland T., Ibegwam C., Jalali M., Johns D., Kline L., Ma D.S., MacCawley S., Magoon A., Mann F., May D., McIntosh T.C., Mehta S., Moy L., Moy M.C., Murphy B.J., Murphy S.D., Nelson K.A., Nuri Z., Parker K.A., Prudhomme A.C., Puri V.N., Qureshi H., Raley J.C., Reardon M.S., Regier M.A., Rogers Y.H., Romblad D.L., Schutz J., Scott J.L., Scott R., Sitter C.D., Smallwood M., Sprague A.C., Stewart E., Strong R.V., Suh E., Sylvester K., Thomas R., Tint N.N., Tsonis C., Wang G., Wang G., Williams M.S., Williams S.M., Windsor S.M., Wolfe K., Wu M.M., Zaveri J., Chaturvedi K., Gabrielian A.E., Ke Z., Sun J., Subramanian G., Venter J.C., Pfannkoch C.M., Barnstead M., Stephenson L.D. Science 296:1661-1671(2002) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE. Strain: Mixed EMBL EDL24919.1.
[8]	"The Transcriptional Landscape of the Mammalian Genome." The FANTOM Consortium, Riken Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group) Science 309:1559-1563(2005) Cited for: NUCLEOTIDE SEQUENCE. Strain: C57BL/6J EMBL BAB27551.1. Tissue: Lung EMBL BAB23416.1 and Whole body EMBL BAB27551.1.
[9]	"Antisense Transcription in the Mammalian Transcriptome." RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group) and the FANTOM Consortium Science 309:1564-1566(2005) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE. Strain: C57BL/6J EMBL BAB27551.1. Tissue: Lung EMBL BAB23416.1 and Whole body EMBL BAB27551.1.
[10]	Mural R.J., Adams M.D., Myers E.W., Smith H.O., Venter J.C. Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE. Strain: Mixed EMBL EDL24919.1.
[11]	"Lineage-specific biology revealed by a finished genome assembly of the mouse." Church D.M., Goodstadt L., Hillier L.W., Zody M.C., Goldstein S., She X., Bult C.J., Agarwala R., Cherry J.L., DiCuccio M., Hlavina W., Kapustin Y., Meric P., Maglott D., Birtle Z., Marques A.C., Graves T., Zhou S. , Teague B., Potamousis K., Churas C., Place M., Herschleb J., Runnheim R., Forrest D., Amos-Landgraf J., Schwartz D.C., Cheng Z., Lindblad-Toh K., Eichler E.E., Ponting C.P. PLoS Biol. 7:E1000112-E1000112(2009) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: C57BL/6J Ensembl ENSMUSP00000129696 Ensembl ENSMUSP00000022314.
[12]	Ensembl Submitted (FEB-2012) to UniProtKB Cited for: IDENTIFICATION. Strain: C57BL/6J Ensembl ENSMUSP00000129696 Ensembl ENSMUSP00000022314.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AC124400 Genomic DNA. No translation available. AK004620 mRNA. Translation: BAB23416.1. AK004788 mRNA. Translation: BAB23565.1. AK011333 mRNA. Translation: BAB27551.1. CH466573 Genomic DNA. Translation: EDL24919.1. CH466573 Genomic DNA. Translation: EDL24922.1.
IPI	IPI00315480.
RefSeq	NP_075623.2. NM_023134.4.
UniGene	Mm.46062.
3D structure databases
SMR	Q9CQI1. Positions 104-248.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
Ensembl	ENSMUST00000022314; ENSMUSP00000022314; ENSMUSG00000021789. ENSMUST00000170719; ENSMUSP00000129696; ENSMUSG00000021789.
GeneID	20387.
KEGG	mmu:20387.
UCSC	uc007tcn.1. mouse.
Organism-specific databases
CTD	653509.
MGI	MGI:109518. Sftpa1.
Phylogenomic databases
GeneTree	ENSGT00700000104102.
HOVERGEN	HBG108270.
InParanoid	Q9CQI1.
KO	K10067.
OMA	CIASPRN.
Gene expression databases
Genevestigator	Q9CQI1.
Family and domain databases
Gene3D	3.10.100.10. 1 hit.
InterPro	IPR001304. C-type_lectin. IPR016186. C-type_lectin-like. IPR018378. C-type_lectin_CS. IPR016187. C-type_lectin_fold. IPR008160. Collagen. [Graphical view]
Pfam	PF01391. Collagen. 2 hits. PF00059. Lectin_C. 1 hit. [Graphical view]
SMART	SM00034. CLECT. 1 hit. [Graphical view]
SUPFAM	SSF56436. C-type_lectin_fold. 1 hit.
PROSITE	PS00615. C_TYPE_LECTIN_1. 1 hit. PS50041. C_TYPE_LECTIN_2. 1 hit. [Graphical view]
ProtoNet	Search...
Other
NextBio	298314.
SOURCE	Search...

Entry information

Entry name

Q9CQI1_MOUSE

Accession

Primary (citable) accession number: Q9CQI1

Entry history

Integrated into UniProtKB/TrEMBL:	June 1, 2001
Last sequence update:	June 1, 2001
Last modified:	May 29, 2013
This is version 96 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)