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Protein
Submitted name:

MCG1040641, isoform CRA_a

Gene

Sftpa1

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Biological processi

Enzyme and pathway databases

ReactomeiR-MMU-166016 Toll Like Receptor 4 (TLR4) Cascade
R-MMU-391160 Signal regulatory protein family interactions
R-MMU-5683826 Surfactant metabolism
R-MMU-5686938 Regulation of TLR by endogenous ligand

Names & Taxonomyi

Protein namesi
Submitted name:
MCG1040641, isoform CRA_aImported
Submitted name:
Pulmonary surfactant-associated protein AImported
Gene namesi
Name:Sftpa1Imported
ORF Names:mCG_1040641Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 14

Organism-specific databases

MGIiMGI:109518 Sftpa1

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 17Sequence analysisAdd BLAST17
ChainiPRO_501509966418 – 248Sequence analysisAdd BLAST231

Keywords - PTMi

Disulfide bondSAAS annotation

Expressioni

Gene expression databases

BgeeiENSMUSG00000021789

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini134 – 247C-type lectinInterPro annotationAdd BLAST114

Keywords - Domaini

SignalSequence analysis

Phylogenomic databases

eggNOGiKOG4297 Eukaryota
ENOG410XPJ1 LUCA
GeneTreeiENSGT00700000104102
HOVERGENiHBG108270
KOiK10067
OMAiTWNDKNC
OrthoDBiEOG091G0PU5
TreeFamiTF330481

Family and domain databases

CDDicd03591 CLECT_collectin_like, 1 hit
Gene3Di3.10.100.10, 1 hit
InterProiView protein in InterPro
IPR001304 C-type_lectin-like
IPR016186 C-type_lectin-like/link_sf
IPR018378 C-type_lectin_CS
IPR033990 Collectin_CTLD
IPR016187 CTDL_fold
PfamiView protein in Pfam
PF00059 Lectin_C, 1 hit
SMARTiView protein in SMART
SM00034 CLECT, 1 hit
SUPFAMiSSF56436 SSF56436, 1 hit
PROSITEiView protein in PROSITE
PS00615 C_TYPE_LECTIN_1, 1 hit
PS50041 C_TYPE_LECTIN_2, 1 hit

Sequencei

Sequence statusi: Complete.

Q9CQI1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSLGSLAFTL FLTVVAGIKC NGTEVCAGSP GIPGTPGNHG LPGRDGRDGI
60 70 80 90 100
KGDPGPPGPM GPPGGMPGLP GRDGLPGAPG APGEHGDKGE PGERGLPGFP
110 120 130 140 150
AYLDEELQTA LYEIKHQILQ TMGVLSLQGS MLSVGDKVFS TNGQSVNFDT
160 170 180 190 200
IREMCTRAGG HIAAPRNPEE NEAIASITKK YNTYPYLGVI EGQTPGDFHY
210 220 230 240
LDGASVNYTN WYPGEPRGRG KEKCVEMYTD GKWNDKGCLQ YRLAICEF
Length:248
Mass (Da):26,183
Last modified:June 1, 2001 - v1
Checksum:i8A5670CFAD3EB9B6
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC124400 Genomic DNA No translation available.
AK004620 mRNA Translation: BAB23416.1
AK004788 mRNA Translation: BAB23565.1
AK011333 mRNA Translation: BAB27551.1
CH466573 Genomic DNA Translation: EDL24919.1
CH466573 Genomic DNA Translation: EDL24922.1
RefSeqiNP_075623.2, NM_023134.4
UniGeneiMm.46062

Genome annotation databases

EnsembliENSMUST00000022314; ENSMUSP00000022314; ENSMUSG00000021789
ENSMUST00000170719; ENSMUSP00000129696; ENSMUSG00000021789
GeneIDi20387
KEGGimmu:20387
UCSCiuc007tcn.1 mouse

Similar proteinsi

Entry informationi

Entry nameiQ9CQI1_MOUSE
AccessioniPrimary (citable) accession number: Q9CQI1
Entry historyiIntegrated into UniProtKB/TrEMBL: June 1, 2001
Last sequence update: June 1, 2001
Last modified: June 20, 2018
This is version 148 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

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