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Q9CQI1

- Q9CQI1_MOUSE

UniProt

Q9CQI1 - Q9CQI1_MOUSE

Protein
Submitted name:

MCG1040641, isoform CRA_a

Gene

Sftpa1

Organism
Mus musculus (Mouse)
Status
Unreviewed - Annotation score: 3 out of 5- Experimental evidence at transcript leveli
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    • History
      Entry version 105 (01 Oct 2014)
      Sequence version 1 (01 Jun 2001)
      Previous versions | rss
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    Functioni

    GO - Molecular functioni

    1. carbohydrate binding Source: InterPro

    GO - Biological processi

    1. cellular response to mechanical stimulus Source: Ensembl
    2. cellular response to nitric oxide Source: Ensembl
    3. circadian rhythm Source: Ensembl
    4. positive regulation of phagocytosis Source: Ensembl
    5. response to epidermal growth factor Source: Ensembl
    6. response to glucocorticoid Source: Ensembl
    7. response to hyperoxia Source: Ensembl
    8. response to hypoxia Source: Ensembl
    9. response to interleukin-6 Source: Ensembl
    10. response to lipopolysaccharide Source: Ensembl
    11. response to retinoic acid Source: Ensembl
    12. response to vitamin A Source: Ensembl

    Keywords - Ligandi

    CalciumSAAS annotation, LectinSAAS annotation

    Enzyme and pathway databases

    ReactomeiREACT_215628. Signal regulatory protein (SIRP) family interactions.

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    MCG1040641, isoform CRA_aImported
    Submitted name:
    Pulmonary surfactant-associated protein AImported
    Gene namesi
    Name:Sftpa1Imported
    ORF Names:mCG_1040641Imported
    OrganismiMus musculus (Mouse)Imported
    Taxonomic identifieri10090 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
    ProteomesiUP000000589: Chromosome 14

    Organism-specific databases

    MGIiMGI:109518. Sftpa1.

    Subcellular locationi

    GO - Cellular componenti

    1. collagen trimer Source: UniProtKB-KW
    2. cytoplasmic vesicle Source: Ensembl
    3. extracellular space Source: Ensembl
    4. multivesicular body Source: Ensembl
    5. rough endoplasmic reticulum Source: Ensembl

    PTM / Processingi

    Keywords - PTMi

    Disulfide bondSAAS annotation

    Expressioni

    Gene expression databases

    GenevestigatoriQ9CQI1.

    Family & Domainsi

    Sequence similaritiesi

    Contains C-type lectin domain.SAAS annotation

    Keywords - Domaini

    CollagenSAAS annotation

    Phylogenomic databases

    GeneTreeiENSGT00700000104102.
    HOVERGENiHBG108270.
    InParanoidiQ9CQI1.
    KOiK10067.
    OMAiEMYTDGK.
    OrthoDBiEOG7HXCVB.
    TreeFamiTF330481.

    Family and domain databases

    Gene3Di3.10.100.10. 1 hit.
    InterProiIPR001304. C-type_lectin.
    IPR016186. C-type_lectin-like.
    IPR018378. C-type_lectin_CS.
    IPR016187. C-type_lectin_fold.
    IPR008160. Collagen.
    [Graphical view]
    PfamiPF01391. Collagen. 2 hits.
    PF00059. Lectin_C. 1 hit.
    [Graphical view]
    SMARTiSM00034. CLECT. 1 hit.
    [Graphical view]
    SUPFAMiSSF56436. SSF56436. 1 hit.
    PROSITEiPS00615. C_TYPE_LECTIN_1. 1 hit.
    PS50041. C_TYPE_LECTIN_2. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q9CQI1-1 [UniParc]FASTAAdd to Basket

    « Hide

    MSLGSLAFTL FLTVVAGIKC NGTEVCAGSP GIPGTPGNHG LPGRDGRDGI    50
    KGDPGPPGPM GPPGGMPGLP GRDGLPGAPG APGEHGDKGE PGERGLPGFP 100
    AYLDEELQTA LYEIKHQILQ TMGVLSLQGS MLSVGDKVFS TNGQSVNFDT 150
    IREMCTRAGG HIAAPRNPEE NEAIASITKK YNTYPYLGVI EGQTPGDFHY 200
    LDGASVNYTN WYPGEPRGRG KEKCVEMYTD GKWNDKGCLQ YRLAICEF 248
    Length:248
    Mass (Da):26,183
    Last modified:June 1, 2001 - v1
    Checksum:i8A5670CFAD3EB9B6
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AC124400 Genomic DNA. No translation available.
    AK004620 mRNA. Translation: BAB23416.1.
    AK004788 mRNA. Translation: BAB23565.1.
    AK011333 mRNA. Translation: BAB27551.1.
    CH466573 Genomic DNA. Translation: EDL24919.1.
    CH466573 Genomic DNA. Translation: EDL24922.1.
    RefSeqiNP_075623.2. NM_023134.4.
    UniGeneiMm.46062.

    Genome annotation databases

    EnsembliENSMUST00000022314; ENSMUSP00000022314; ENSMUSG00000021789.
    ENSMUST00000170719; ENSMUSP00000129696; ENSMUSG00000021789.
    GeneIDi20387.
    KEGGimmu:20387.
    UCSCiuc007tcn.1. mouse.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AC124400 Genomic DNA. No translation available.
    AK004620 mRNA. Translation: BAB23416.1 .
    AK004788 mRNA. Translation: BAB23565.1 .
    AK011333 mRNA. Translation: BAB27551.1 .
    CH466573 Genomic DNA. Translation: EDL24919.1 .
    CH466573 Genomic DNA. Translation: EDL24922.1 .
    RefSeqi NP_075623.2. NM_023134.4.
    UniGenei Mm.46062.

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    Ensembli ENSMUST00000022314 ; ENSMUSP00000022314 ; ENSMUSG00000021789 .
    ENSMUST00000170719 ; ENSMUSP00000129696 ; ENSMUSG00000021789 .
    GeneIDi 20387.
    KEGGi mmu:20387.
    UCSCi uc007tcn.1. mouse.

    Organism-specific databases

    CTDi 653509.
    MGIi MGI:109518. Sftpa1.

    Phylogenomic databases

    GeneTreei ENSGT00700000104102.
    HOVERGENi HBG108270.
    InParanoidi Q9CQI1.
    KOi K10067.
    OMAi EMYTDGK.
    OrthoDBi EOG7HXCVB.
    TreeFami TF330481.

    Enzyme and pathway databases

    Reactomei REACT_215628. Signal regulatory protein (SIRP) family interactions.

    Miscellaneous databases

    NextBioi 298314.
    SOURCEi Search...

    Gene expression databases

    Genevestigatori Q9CQI1.

    Family and domain databases

    Gene3Di 3.10.100.10. 1 hit.
    InterProi IPR001304. C-type_lectin.
    IPR016186. C-type_lectin-like.
    IPR018378. C-type_lectin_CS.
    IPR016187. C-type_lectin_fold.
    IPR008160. Collagen.
    [Graphical view ]
    Pfami PF01391. Collagen. 2 hits.
    PF00059. Lectin_C. 1 hit.
    [Graphical view ]
    SMARTi SM00034. CLECT. 1 hit.
    [Graphical view ]
    SUPFAMi SSF56436. SSF56436. 1 hit.
    PROSITEi PS00615. C_TYPE_LECTIN_1. 1 hit.
    PS50041. C_TYPE_LECTIN_2. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "High-efficiency full-length cDNA cloning."
      Carninci P., Hayashizaki Y.
      Methods Enzymol. 303:19-44(1999) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE.
      Strain: C57BL/6JImported.
      Tissue: LungImported and Whole bodyImported.
    2. "Normalization and subtraction of cap-trapper-selected cDNAs to prepare full-length cDNA libraries for rapid discovery of new genes."
      Carninci P., Shibata Y., Hayatsu N., Sugahara Y., Shibata K., Itoh M., Konno H., Okazaki Y., Muramatsu M., Hayashizaki Y.
      Genome Res. 10:1617-1630(2000) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE.
      Strain: C57BL/6JImported.
      Tissue: LungImported and Whole bodyImported.
    3. Cited for: NUCLEOTIDE SEQUENCE.
      Strain: C57BL/6JImported.
      Tissue: LungImported and Whole bodyImported.
    4. Cited for: NUCLEOTIDE SEQUENCE.
      Strain: C57BL/6JImported.
      Tissue: LungImported and Whole bodyImported.
    5. "Functional annotation of a full-length mouse cDNA collection."
      The RIKEN Genome Exploration Research Group Phase II Team and the FANTOM Consortium
      Nature 409:685-690(2001)
      Cited for: NUCLEOTIDE SEQUENCE.
      Strain: C57BL/6JImported.
      Tissue: LungImported and Whole bodyImported.
    6. "Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs."
      The FANTOM Consortium and the RIKEN Genome Exploration Research Group Phase I and II Team
      Nature 420:563-573(2002)
      Cited for: NUCLEOTIDE SEQUENCE.
      Strain: C57BL/6JImported.
      Tissue: LungImported and Whole bodyImported.
    7. "A comparison of whole-genome shotgun-derived mouse chromosome 16 and the human genome."
      Mural R.J., Adams M.D., Myers E.W., Smith H.O., Miklos G.L., Wides R., Halpern A., Li P.W., Sutton G.G., Nadeau J., Salzberg S.L., Holt R.A., Kodira C.D., Lu F., Chen L., Deng Z., Evangelista C.C., Gan W.
      , Heiman T.J., Li J., Li Z., Merkulov G.V., Milshina N.V., Naik A.K., Qi R., Shue B.C., Wang A., Wang J., Wang X., Yan X., Ye J., Yooseph S., Zhao Q., Zheng L., Zhu S.C., Biddick K., Bolanos R., Delcher A.L., Dew I.M., Fasulo D., Flanigan M.J., Huson D.H., Kravitz S.A., Miller J.R., Mobarry C.M., Reinert K., Remington K.A., Zhang Q., Zheng X.H., Nusskern D.R., Lai Z., Lei Y., Zhong W., Yao A., Guan P., Ji R.R., Gu Z., Wang Z.Y., Zhong F., Xiao C., Chiang C.C., Yandell M., Wortman J.R., Amanatides P.G., Hladun S.L., Pratts E.C., Johnson J.E., Dodson K.L., Woodford K.J., Evans C.A., Gropman B., Rusch D.B., Venter E., Wang M., Smith T.J., Houck J.T., Tompkins D.E., Haynes C., Jacob D., Chin S.H., Allen D.R., Dahlke C.E., Sanders R., Li K., Liu X., Levitsky A.A., Majoros W.H., Chen Q., Xia A.C., Lopez J.R., Donnelly M.T., Newman M.H., Glodek A., Kraft C.L., Nodell M., Ali F., An H.J., Baldwin-Pitts D., Beeson K.Y., Cai S., Carnes M., Carver A., Caulk P.M., Center A., Chen Y.H., Cheng M.L., Coyne M.D., Crowder M., Danaher S., Davenport L.B., Desilets R., Dietz S.M., Doup L., Dullaghan P., Ferriera S., Fosler C.R., Gire H.C., Gluecksmann A., Gocayne J.D., Gray J., Hart B., Haynes J., Hoover J., Howland T., Ibegwam C., Jalali M., Johns D., Kline L., Ma D.S., MacCawley S., Magoon A., Mann F., May D., McIntosh T.C., Mehta S., Moy L., Moy M.C., Murphy B.J., Murphy S.D., Nelson K.A., Nuri Z., Parker K.A., Prudhomme A.C., Puri V.N., Qureshi H., Raley J.C., Reardon M.S., Regier M.A., Rogers Y.H., Romblad D.L., Schutz J., Scott J.L., Scott R., Sitter C.D., Smallwood M., Sprague A.C., Stewart E., Strong R.V., Suh E., Sylvester K., Thomas R., Tint N.N., Tsonis C., Wang G., Wang G., Williams M.S., Williams S.M., Windsor S.M., Wolfe K., Wu M.M., Zaveri J., Chaturvedi K., Gabrielian A.E., Ke Z., Sun J., Subramanian G., Venter J.C., Pfannkoch C.M., Barnstead M., Stephenson L.D.
      Science 296:1661-1671(2002) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE.
      Strain: MixedImported.
    8. "The Transcriptional Landscape of the Mammalian Genome."
      The FANTOM Consortium, Riken Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group)
      Science 309:1559-1563(2005)
      Cited for: NUCLEOTIDE SEQUENCE.
      Strain: C57BL/6JImported.
      Tissue: LungImported and Whole bodyImported.
    9. Cited for: NUCLEOTIDE SEQUENCE.
      Strain: C57BL/6JImported.
      Tissue: LungImported and Whole bodyImported.
    10. Mural R.J., Adams M.D., Myers E.W., Smith H.O., Venter J.C.
      Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE.
      Strain: MixedImported.
    11. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: C57BL/6JImported.
    12. Ensembl
      Submitted (FEB-2012) to UniProtKB
      Cited for: IDENTIFICATION.
      Strain: C57BL/6JImported.

    Entry informationi

    Entry nameiQ9CQI1_MOUSE
    AccessioniPrimary (citable) accession number: Q9CQI1
    Entry historyi
    Integrated into UniProtKB/TrEMBL: June 1, 2001
    Last sequence update: June 1, 2001
    Last modified: October 1, 2014
    This is version 105 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3