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Protein

Ribonuclease P protein subunit p14

Gene

Rpp14

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends.By similarity

Catalytic activityi

Endonucleolytic cleavage of RNA, removing 5'-extranucleotides from tRNA precursor.

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionHydrolase
Biological processtRNA processing

Names & Taxonomyi

Protein namesi
Recommended name:
Ribonuclease P protein subunit p14 (EC:3.1.26.5)
Gene namesi
Name:Rpp14
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 14

Organism-specific databases

MGIiMGI:1914303. Rpp14.

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001400111 – 122Ribonuclease P protein subunit p14Add BLAST122

Proteomic databases

EPDiQ9CQH8.
MaxQBiQ9CQH8.
PaxDbiQ9CQH8.
PeptideAtlasiQ9CQH8.
PRIDEiQ9CQH8.

PTM databases

iPTMnetiQ9CQH8.
PhosphoSitePlusiQ9CQH8.

Expressioni

Gene expression databases

BgeeiENSMUSG00000023156.
CleanExiMM_RPP14.
ExpressionAtlasiQ9CQH8. baseline and differential.
GenevisibleiQ9CQH8. MM.

Interactioni

Subunit structurei

RNase P consists of an RNA moiety and at least 8 protein subunits; POP1, RPP14, RPP20/POP7, RPP25, RPP29/POP4, RPP30, RPP38 and RPP40.By similarity

Protein-protein interaction databases

IntActiQ9CQH8. 1 interactor.
STRINGi10090.ENSMUSP00000023924.

Structurei

3D structure databases

ProteinModelPortaliQ9CQH8.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiENOG410IXUB. Eukaryota.
ENOG4112ADM. LUCA.
GeneTreeiENSGT00510000048121.
HOGENOMiHOG000006985.
HOVERGENiHBG079505.
InParanoidiQ9CQH8.
KOiK14529.
OrthoDBiEOG091G10J1.
PhylomeDBiQ9CQH8.
TreeFamiTF324711.

Family and domain databases

InterProiView protein in InterPro
IPR002759. RNase_P/MRP_subunit.
PfamiView protein in Pfam
PF01900. RNase_P_Rpp14. 1 hit.

Sequencei

Sequence statusi: Complete.

Q9CQH8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MPATAYERVV YKSPSEYHYM KVCLEFQEHG VGLNVAQFKQ LLVSALRDLF
60 70 80 90 100
GEVGAALPVD VLTYDEKTLS AILRICSSGL VKLWSSLTLF GAYKSKKCAF
110 120
RVIQVSPFLL ALSGNSREQV LD
Length:122
Mass (Da):13,565
Last modified:June 1, 2001 - v1
Checksum:i8B66600CB7AB6239
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK012105 mRNA. Translation: BAB28036.1.
AK016631 mRNA. Translation: BAB30347.1.
BC026988 mRNA. Translation: AAH26988.1.
BC046803 mRNA. Translation: AAH46803.1.
CCDSiCCDS26809.1.
RefSeqiNP_080214.1. NM_025938.4.
XP_006518153.1. XM_006518090.2.
XP_006518154.1. XM_006518091.2.
UniGeneiMm.210048.

Genome annotation databases

EnsembliENSMUST00000023924; ENSMUSP00000023924; ENSMUSG00000023156.
GeneIDi67053.
KEGGimmu:67053.
UCSCiuc007seq.2. mouse.

Similar proteinsi

Entry informationi

Entry nameiRPP14_MOUSE
AccessioniPrimary (citable) accession number: Q9CQH8
Entry historyiIntegrated into UniProtKB/Swiss-Prot: April 26, 2005
Last sequence update: June 1, 2001
Last modified: October 25, 2017
This is version 104 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
  2. SIMILARITY comments
    Index of protein domains and families