Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Ribonuclease P protein subunit p14

Gene

Rpp14

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends.By similarity

Catalytic activityi

Endonucleolytic cleavage of RNA, removing 5'-extranucleotides from tRNA precursor.

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Hydrolase

Keywords - Biological processi

tRNA processing

Names & Taxonomyi

Protein namesi
Recommended name:
Ribonuclease P protein subunit p14 (EC:3.1.26.5)
Gene namesi
Name:Rpp14
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
ProteomesiUP000000589 Componenti: Chromosome 14

Organism-specific databases

MGIiMGI:1914303. Rpp14.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 122122Ribonuclease P protein subunit p14PRO_0000140011Add
BLAST

Proteomic databases

MaxQBiQ9CQH8.
PaxDbiQ9CQH8.
PRIDEiQ9CQH8.

Expressioni

Gene expression databases

BgeeiQ9CQH8.
CleanExiMM_RPP14.
GenevestigatoriQ9CQH8.

Interactioni

Subunit structurei

RNase P consists of an RNA moiety and at least 8 protein subunits; POP1, RPP14, RPP20/POP7, RPP25, RPP29/POP4, RPP30, RPP38 and RPP40.By similarity

Protein-protein interaction databases

IntActiQ9CQH8. 1 interaction.
STRINGi10090.ENSMUSP00000023924.

Structurei

3D structure databases

ProteinModelPortaliQ9CQH8.
SMRiQ9CQH8. Positions 16-112.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiNOG77977.
GeneTreeiENSGT00510000048121.
HOGENOMiHOG000006985.
HOVERGENiHBG079505.
InParanoidiQ9CQH8.
KOiK14529.
OMAiHHYMKVC.
OrthoDBiEOG7VDXS1.
PhylomeDBiQ9CQH8.
TreeFamiTF324711.

Family and domain databases

InterProiIPR002759. RNase_P/MRP_subunit.
[Graphical view]
PfamiPF01900. RNase_P_Rpp14. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q9CQH8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MPATAYERVV YKSPSEYHYM KVCLEFQEHG VGLNVAQFKQ LLVSALRDLF
60 70 80 90 100
GEVGAALPVD VLTYDEKTLS AILRICSSGL VKLWSSLTLF GAYKSKKCAF
110 120
RVIQVSPFLL ALSGNSREQV LD
Length:122
Mass (Da):13,565
Last modified:June 1, 2001 - v1
Checksum:i8B66600CB7AB6239
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK012105 mRNA. Translation: BAB28036.1.
AK016631 mRNA. Translation: BAB30347.1.
BC026988 mRNA. Translation: AAH26988.1.
BC046803 mRNA. Translation: AAH46803.1.
CCDSiCCDS26809.1.
RefSeqiNP_080214.1. NM_025938.4.
XP_006518153.1. XM_006518090.2.
XP_006518154.1. XM_006518091.2.
UniGeneiMm.210048.

Genome annotation databases

EnsembliENSMUST00000023924; ENSMUSP00000023924; ENSMUSG00000023156.
GeneIDi67053.
KEGGimmu:67053.
UCSCiuc007seq.2. mouse.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK012105 mRNA. Translation: BAB28036.1.
AK016631 mRNA. Translation: BAB30347.1.
BC026988 mRNA. Translation: AAH26988.1.
BC046803 mRNA. Translation: AAH46803.1.
CCDSiCCDS26809.1.
RefSeqiNP_080214.1. NM_025938.4.
XP_006518153.1. XM_006518090.2.
XP_006518154.1. XM_006518091.2.
UniGeneiMm.210048.

3D structure databases

ProteinModelPortaliQ9CQH8.
SMRiQ9CQH8. Positions 16-112.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

IntActiQ9CQH8. 1 interaction.
STRINGi10090.ENSMUSP00000023924.

Proteomic databases

MaxQBiQ9CQH8.
PaxDbiQ9CQH8.
PRIDEiQ9CQH8.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000023924; ENSMUSP00000023924; ENSMUSG00000023156.
GeneIDi67053.
KEGGimmu:67053.
UCSCiuc007seq.2. mouse.

Organism-specific databases

CTDi11102.
MGIiMGI:1914303. Rpp14.

Phylogenomic databases

eggNOGiNOG77977.
GeneTreeiENSGT00510000048121.
HOGENOMiHOG000006985.
HOVERGENiHBG079505.
InParanoidiQ9CQH8.
KOiK14529.
OMAiHHYMKVC.
OrthoDBiEOG7VDXS1.
PhylomeDBiQ9CQH8.
TreeFamiTF324711.

Miscellaneous databases

NextBioi323436.
PROiQ9CQH8.
SOURCEiSearch...

Gene expression databases

BgeeiQ9CQH8.
CleanExiMM_RPP14.
GenevestigatoriQ9CQH8.

Family and domain databases

InterProiIPR002759. RNase_P/MRP_subunit.
[Graphical view]
PfamiPF01900. RNase_P_Rpp14. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "The transcriptional landscape of the mammalian genome."
    Carninci P., Kasukawa T., Katayama S., Gough J., Frith M.C., Maeda N., Oyama R., Ravasi T., Lenhard B., Wells C., Kodzius R., Shimokawa K., Bajic V.B., Brenner S.E., Batalov S., Forrest A.R., Zavolan M., Davis M.J.
    , Wilming L.G., Aidinis V., Allen J.E., Ambesi-Impiombato A., Apweiler R., Aturaliya R.N., Bailey T.L., Bansal M., Baxter L., Beisel K.W., Bersano T., Bono H., Chalk A.M., Chiu K.P., Choudhary V., Christoffels A., Clutterbuck D.R., Crowe M.L., Dalla E., Dalrymple B.P., de Bono B., Della Gatta G., di Bernardo D., Down T., Engstrom P., Fagiolini M., Faulkner G., Fletcher C.F., Fukushima T., Furuno M., Futaki S., Gariboldi M., Georgii-Hemming P., Gingeras T.R., Gojobori T., Green R.E., Gustincich S., Harbers M., Hayashi Y., Hensch T.K., Hirokawa N., Hill D., Huminiecki L., Iacono M., Ikeo K., Iwama A., Ishikawa T., Jakt M., Kanapin A., Katoh M., Kawasawa Y., Kelso J., Kitamura H., Kitano H., Kollias G., Krishnan S.P., Kruger A., Kummerfeld S.K., Kurochkin I.V., Lareau L.F., Lazarevic D., Lipovich L., Liu J., Liuni S., McWilliam S., Madan Babu M., Madera M., Marchionni L., Matsuda H., Matsuzawa S., Miki H., Mignone F., Miyake S., Morris K., Mottagui-Tabar S., Mulder N., Nakano N., Nakauchi H., Ng P., Nilsson R., Nishiguchi S., Nishikawa S., Nori F., Ohara O., Okazaki Y., Orlando V., Pang K.C., Pavan W.J., Pavesi G., Pesole G., Petrovsky N., Piazza S., Reed J., Reid J.F., Ring B.Z., Ringwald M., Rost B., Ruan Y., Salzberg S.L., Sandelin A., Schneider C., Schoenbach C., Sekiguchi K., Semple C.A., Seno S., Sessa L., Sheng Y., Shibata Y., Shimada H., Shimada K., Silva D., Sinclair B., Sperling S., Stupka E., Sugiura K., Sultana R., Takenaka Y., Taki K., Tammoja K., Tan S.L., Tang S., Taylor M.S., Tegner J., Teichmann S.A., Ueda H.R., van Nimwegen E., Verardo R., Wei C.L., Yagi K., Yamanishi H., Zabarovsky E., Zhu S., Zimmer A., Hide W., Bult C., Grimmond S.M., Teasdale R.D., Liu E.T., Brusic V., Quackenbush J., Wahlestedt C., Mattick J.S., Hume D.A., Kai C., Sasaki D., Tomaru Y., Fukuda S., Kanamori-Katayama M., Suzuki M., Aoki J., Arakawa T., Iida J., Imamura K., Itoh M., Kato T., Kawaji H., Kawagashira N., Kawashima T., Kojima M., Kondo S., Konno H., Nakano K., Ninomiya N., Nishio T., Okada M., Plessy C., Shibata K., Shiraki T., Suzuki S., Tagami M., Waki K., Watahiki A., Okamura-Oho Y., Suzuki H., Kawai J., Hayashizaki Y.
    Science 309:1559-1563(2005) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Strain: C57BL/6J.
    Tissue: Embryo and Testis.
  2. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Strain: C57BL/6.
    Tissue: Brain and Eye.

Entry informationi

Entry nameiRPP14_MOUSE
AccessioniPrimary (citable) accession number: Q9CQH8
Entry historyi
Integrated into UniProtKB/Swiss-Prot: April 26, 2005
Last sequence update: June 1, 2001
Last modified: April 1, 2015
This is version 87 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.