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Q9CQH8

- RPP14_MOUSE

UniProt

Q9CQH8 - RPP14_MOUSE

Protein

Ribonuclease P protein subunit p14

Gene

Rpp14

Organism
Mus musculus (Mouse)
Status
Reviewed - Annotation score: 2 out of 5- Experimental evidence at transcript leveli
  1. Functioni

    Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends.By similarity

    Catalytic activityi

    Endonucleolytic cleavage of RNA, removing 5'-extranucleotides from tRNA precursor.

    GO - Molecular functioni

    1. ribonuclease P activity Source: UniProtKB-EC

    GO - Biological processi

    1. tRNA processing Source: UniProtKB-KW

    Keywords - Molecular functioni

    Hydrolase

    Keywords - Biological processi

    tRNA processing

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Ribonuclease P protein subunit p14 (EC:3.1.26.5)
    Gene namesi
    Name:Rpp14
    OrganismiMus musculus (Mouse)
    Taxonomic identifieri10090 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
    ProteomesiUP000000589: Chromosome 14

    Organism-specific databases

    MGIiMGI:1914303. Rpp14.

    Subcellular locationi

    Nucleus Curated

    GO - Cellular componenti

    1. nucleus Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Nucleus

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 122122Ribonuclease P protein subunit p14PRO_0000140011Add
    BLAST

    Proteomic databases

    PaxDbiQ9CQH8.
    PRIDEiQ9CQH8.

    Expressioni

    Gene expression databases

    BgeeiQ9CQH8.
    CleanExiMM_RPP14.
    GenevestigatoriQ9CQH8.

    Interactioni

    Subunit structurei

    RNase P consists of an RNA moiety and at least 8 protein subunits; POP1, RPP14, RPP20/POP7, RPP25, RPP29/POP4, RPP30, RPP38 and RPP40.By similarity

    Protein-protein interaction databases

    IntActiQ9CQH8. 1 interaction.
    STRINGi10090.ENSMUSP00000023924.

    Structurei

    3D structure databases

    ProteinModelPortaliQ9CQH8.
    SMRiQ9CQH8. Positions 16-112.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Phylogenomic databases

    eggNOGiNOG77977.
    GeneTreeiENSGT00510000048121.
    HOGENOMiHOG000006985.
    HOVERGENiHBG079505.
    InParanoidiQ9CQH8.
    KOiK14529.
    OMAiHHYMKVC.
    OrthoDBiEOG7VDXS1.
    PhylomeDBiQ9CQH8.
    TreeFamiTF324711.

    Family and domain databases

    InterProiIPR002759. RNase_P/MRP_subunit.
    [Graphical view]
    PfamiPF01900. RNase_P_Rpp14. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q9CQH8-1 [UniParc]FASTAAdd to Basket

    « Hide

    MPATAYERVV YKSPSEYHYM KVCLEFQEHG VGLNVAQFKQ LLVSALRDLF    50
    GEVGAALPVD VLTYDEKTLS AILRICSSGL VKLWSSLTLF GAYKSKKCAF 100
    RVIQVSPFLL ALSGNSREQV LD 122
    Length:122
    Mass (Da):13,565
    Last modified:June 1, 2001 - v1
    Checksum:i8B66600CB7AB6239
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AK012105 mRNA. Translation: BAB28036.1.
    AK016631 mRNA. Translation: BAB30347.1.
    BC026988 mRNA. Translation: AAH26988.1.
    BC046803 mRNA. Translation: AAH46803.1.
    CCDSiCCDS26809.1.
    RefSeqiNP_080214.1. NM_025938.4.
    XP_006518153.1. XM_006518090.1.
    XP_006518154.1. XM_006518091.1.
    UniGeneiMm.210048.

    Genome annotation databases

    EnsembliENSMUST00000023924; ENSMUSP00000023924; ENSMUSG00000023156.
    GeneIDi67053.
    KEGGimmu:67053.
    UCSCiuc007seq.2. mouse.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AK012105 mRNA. Translation: BAB28036.1 .
    AK016631 mRNA. Translation: BAB30347.1 .
    BC026988 mRNA. Translation: AAH26988.1 .
    BC046803 mRNA. Translation: AAH46803.1 .
    CCDSi CCDS26809.1.
    RefSeqi NP_080214.1. NM_025938.4.
    XP_006518153.1. XM_006518090.1.
    XP_006518154.1. XM_006518091.1.
    UniGenei Mm.210048.

    3D structure databases

    ProteinModelPortali Q9CQH8.
    SMRi Q9CQH8. Positions 16-112.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    IntActi Q9CQH8. 1 interaction.
    STRINGi 10090.ENSMUSP00000023924.

    Proteomic databases

    PaxDbi Q9CQH8.
    PRIDEi Q9CQH8.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    Ensembli ENSMUST00000023924 ; ENSMUSP00000023924 ; ENSMUSG00000023156 .
    GeneIDi 67053.
    KEGGi mmu:67053.
    UCSCi uc007seq.2. mouse.

    Organism-specific databases

    CTDi 11102.
    MGIi MGI:1914303. Rpp14.

    Phylogenomic databases

    eggNOGi NOG77977.
    GeneTreei ENSGT00510000048121.
    HOGENOMi HOG000006985.
    HOVERGENi HBG079505.
    InParanoidi Q9CQH8.
    KOi K14529.
    OMAi HHYMKVC.
    OrthoDBi EOG7VDXS1.
    PhylomeDBi Q9CQH8.
    TreeFami TF324711.

    Miscellaneous databases

    NextBioi 323436.
    PROi Q9CQH8.
    SOURCEi Search...

    Gene expression databases

    Bgeei Q9CQH8.
    CleanExi MM_RPP14.
    Genevestigatori Q9CQH8.

    Family and domain databases

    InterProi IPR002759. RNase_P/MRP_subunit.
    [Graphical view ]
    Pfami PF01900. RNase_P_Rpp14. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "The transcriptional landscape of the mammalian genome."
      Carninci P., Kasukawa T., Katayama S., Gough J., Frith M.C., Maeda N., Oyama R., Ravasi T., Lenhard B., Wells C., Kodzius R., Shimokawa K., Bajic V.B., Brenner S.E., Batalov S., Forrest A.R., Zavolan M., Davis M.J.
      , Wilming L.G., Aidinis V., Allen J.E., Ambesi-Impiombato A., Apweiler R., Aturaliya R.N., Bailey T.L., Bansal M., Baxter L., Beisel K.W., Bersano T., Bono H., Chalk A.M., Chiu K.P., Choudhary V., Christoffels A., Clutterbuck D.R., Crowe M.L., Dalla E., Dalrymple B.P., de Bono B., Della Gatta G., di Bernardo D., Down T., Engstrom P., Fagiolini M., Faulkner G., Fletcher C.F., Fukushima T., Furuno M., Futaki S., Gariboldi M., Georgii-Hemming P., Gingeras T.R., Gojobori T., Green R.E., Gustincich S., Harbers M., Hayashi Y., Hensch T.K., Hirokawa N., Hill D., Huminiecki L., Iacono M., Ikeo K., Iwama A., Ishikawa T., Jakt M., Kanapin A., Katoh M., Kawasawa Y., Kelso J., Kitamura H., Kitano H., Kollias G., Krishnan S.P., Kruger A., Kummerfeld S.K., Kurochkin I.V., Lareau L.F., Lazarevic D., Lipovich L., Liu J., Liuni S., McWilliam S., Madan Babu M., Madera M., Marchionni L., Matsuda H., Matsuzawa S., Miki H., Mignone F., Miyake S., Morris K., Mottagui-Tabar S., Mulder N., Nakano N., Nakauchi H., Ng P., Nilsson R., Nishiguchi S., Nishikawa S., Nori F., Ohara O., Okazaki Y., Orlando V., Pang K.C., Pavan W.J., Pavesi G., Pesole G., Petrovsky N., Piazza S., Reed J., Reid J.F., Ring B.Z., Ringwald M., Rost B., Ruan Y., Salzberg S.L., Sandelin A., Schneider C., Schoenbach C., Sekiguchi K., Semple C.A., Seno S., Sessa L., Sheng Y., Shibata Y., Shimada H., Shimada K., Silva D., Sinclair B., Sperling S., Stupka E., Sugiura K., Sultana R., Takenaka Y., Taki K., Tammoja K., Tan S.L., Tang S., Taylor M.S., Tegner J., Teichmann S.A., Ueda H.R., van Nimwegen E., Verardo R., Wei C.L., Yagi K., Yamanishi H., Zabarovsky E., Zhu S., Zimmer A., Hide W., Bult C., Grimmond S.M., Teasdale R.D., Liu E.T., Brusic V., Quackenbush J., Wahlestedt C., Mattick J.S., Hume D.A., Kai C., Sasaki D., Tomaru Y., Fukuda S., Kanamori-Katayama M., Suzuki M., Aoki J., Arakawa T., Iida J., Imamura K., Itoh M., Kato T., Kawaji H., Kawagashira N., Kawashima T., Kojima M., Kondo S., Konno H., Nakano K., Ninomiya N., Nishio T., Okada M., Plessy C., Shibata K., Shiraki T., Suzuki S., Tagami M., Waki K., Watahiki A., Okamura-Oho Y., Suzuki H., Kawai J., Hayashizaki Y.
      Science 309:1559-1563(2005) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
      Strain: C57BL/6J.
      Tissue: Embryo and Testis.
    2. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
      Strain: C57BL/6.
      Tissue: Brain and Eye.

    Entry informationi

    Entry nameiRPP14_MOUSE
    AccessioniPrimary (citable) accession number: Q9CQH8
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: April 26, 2005
    Last sequence update: June 1, 2001
    Last modified: October 1, 2014
    This is version 84 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programChordata Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. MGD cross-references
      Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3