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Q9CQG8

- Q9CQG8_MOUSE

UniProt

Q9CQG8 - Q9CQG8_MOUSE

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Protein
Submitted name:

Putative uncharacterized protein

Gene

Lrrk2

Organism
Mus musculus (Mouse)
Status
Unreviewed - Annotation score: 3 out of 5- Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

  1. ATP binding Source: InterPro
  2. GTP binding Source: MGI
  3. GTP-dependent protein kinase activity Source: MGI

GO - Biological processi

  1. negative regulation of GTPase activity Source: MGI
  2. protein autophosphorylation Source: MGI
  3. protein phosphorylation Source: MGI
Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
Putative uncharacterized proteinImported
Gene namesi
Name:Lrrk2Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus

Organism-specific databases

MGIiMGI:1913975. Lrrk2.

Subcellular locationi

GO - Cellular componenti

  1. membrane raft Source: MGI
  2. plasma membrane Source: MGI
  3. synapse Source: MGI
  4. synaptic vesicle Source: MGI
  5. trans-Golgi network Source: MGI
Complete GO annotation...

Expressioni

Gene expression databases

GenevestigatoriQ9CQG8.

Family & Domainsi

Phylogenomic databases

HOVERGENiHBG075871.
KOiK08844.

Family and domain databases

Gene3Di2.130.10.10. 1 hit.
InterProiIPR011009. Kinase-like_dom.
IPR000719. Prot_kinase_dom.
IPR008271. Ser/Thr_kinase_AS.
IPR015943. WD40/YVTN_repeat-like_dom.
IPR001680. WD40_repeat.
IPR017986. WD40_repeat_dom.
[Graphical view]
PfamiPF00069. Pkinase. 1 hit.
[Graphical view]
SMARTiSM00320. WD40. 2 hits.
[Graphical view]
SUPFAMiSSF50978. SSF50978. 1 hit.
SSF56112. SSF56112. 1 hit.
PROSITEiPS50011. PROTEIN_KINASE_DOM. 1 hit.
PS00108. PROTEIN_KINASE_ST. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q9CQG8-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MLGAIFERPI PPDTRPWYLH SAMIIYRDLK PHNVLLFTLY PNAAIIAKIA
60 70 80 90 100
DYGIAQYCCR MGIKTSEGTP GFRAPEVARG NVIYNQQADV YSFGLLLHDI
110 120 130 140 150
WTTGSRIMEG LRFPNEFDEL AIQGKLPDPV KEYGCAPWPM VEKLITKCLK
160 170 180 190 200
ENPQERPTSA QVFDILNSAE LICLMRHILI PKNIIVECMV ATNLNSKSAT
210 220 230 240 250
LWLGCGNTEK GQLSLFDLNT ERYSYEEVAD SRILCLALVH LAAEKESWVV
260 270 280 290 300
CGTQSGALLV INVEEETKRH TLEKMTDSVT CLHCNSLAKQ SKQSNFLLVG
310 320 330 340 350
TADGNLMIFE DKAVKCKGAA PLKTLHIGDV STPLMCLSES LNSSERHITW
360 370 380 390 400
GGCGTKVFSF SNDFTIQKLI ETKTNQLFSY AAFSDSNIIA LAVDTALYIA
410 420 430 440 450
KKNSPVVEVW DKKTEKLCEL IDCVHFLKEV MVKLNKESKH QLSYSGRVKA
460 470 480 490 500
LCLQKNTALW IGTGGGHILL LDLSTRRVIR TIHNFCDSVR AMATAQLGSL
510 520 530 540 550
KNVMLVLGYK RKSTEGIQEQ KEIQSCLSIW DLNLPHEVQN LEKHIEVRTE
560
LADKMRKTSV E
Length:561
Mass (Da):62,834
Last modified:June 1, 2001 - v1
Checksum:i8EB2B26C99F1D293
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK014886 mRNA. Translation: BAB29603.1.
AK014938 mRNA. Translation: BAB29628.1.
RefSeqiNP_080006.3. NM_025730.3.
UniGeneiMm.37558.

Genome annotation databases

GeneIDi66725.
KEGGimmu:66725.
UCSCiuc007xia.1. mouse.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK014886 mRNA. Translation: BAB29603.1 .
AK014938 mRNA. Translation: BAB29628.1 .
RefSeqi NP_080006.3. NM_025730.3.
UniGenei Mm.37558.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

GeneIDi 66725.
KEGGi mmu:66725.
UCSCi uc007xia.1. mouse.

Organism-specific databases

CTDi 120892.
MGIi MGI:1913975. Lrrk2.

Phylogenomic databases

HOVERGENi HBG075871.
KOi K08844.

Miscellaneous databases

NextBioi 322485.
SOURCEi Search...

Gene expression databases

Genevestigatori Q9CQG8.

Family and domain databases

Gene3Di 2.130.10.10. 1 hit.
InterProi IPR011009. Kinase-like_dom.
IPR000719. Prot_kinase_dom.
IPR008271. Ser/Thr_kinase_AS.
IPR015943. WD40/YVTN_repeat-like_dom.
IPR001680. WD40_repeat.
IPR017986. WD40_repeat_dom.
[Graphical view ]
Pfami PF00069. Pkinase. 1 hit.
[Graphical view ]
SMARTi SM00320. WD40. 2 hits.
[Graphical view ]
SUPFAMi SSF50978. SSF50978. 1 hit.
SSF56112. SSF56112. 1 hit.
PROSITEi PS50011. PROTEIN_KINASE_DOM. 1 hit.
PS00108. PROTEIN_KINASE_ST. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "High-efficiency full-length cDNA cloning."
    Carninci P., Hayashizaki Y.
    Methods Enzymol. 303:19-44(1999) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
    Tissue: TestisImported.
  2. "Normalization and subtraction of cap-trapper-selected cDNAs to prepare full-length cDNA libraries for rapid discovery of new genes."
    Carninci P., Shibata Y., Hayatsu N., Sugahara Y., Shibata K., Itoh M., Konno H., Okazaki Y., Muramatsu M., Hayashizaki Y.
    Genome Res. 10:1617-1630(2000) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
    Tissue: TestisImported.
  3. Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
    Tissue: TestisImported.
  4. Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
    Tissue: TestisImported.
  5. "Functional annotation of a full-length mouse cDNA collection."
    The RIKEN Genome Exploration Research Group Phase II Team and the FANTOM Consortium
    Nature 409:685-690(2001)
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
    Tissue: TestisImported.
  6. "Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs."
    The FANTOM Consortium and the RIKEN Genome Exploration Research Group Phase I and II Team
    Nature 420:563-573(2002)
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
    Tissue: TestisImported.
  7. "The Transcriptional Landscape of the Mammalian Genome."
    The FANTOM Consortium, Riken Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group)
    Science 309:1559-1563(2005)
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
    Tissue: TestisImported.
  8. Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
    Tissue: TestisImported.

Entry informationi

Entry nameiQ9CQG8_MOUSE
AccessioniPrimary (citable) accession number: Q9CQG8
Entry historyi
Integrated into UniProtKB/TrEMBL: June 1, 2001
Last sequence update: June 1, 2001
Last modified: October 29, 2014
This is version 97 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)