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Q9CQG8

- Q9CQG8_MOUSE

UniProt

Q9CQG8 - Q9CQG8_MOUSE

Protein
Submitted name:

Putative uncharacterized protein

Gene

Lrrk2

Organism
Mus musculus (Mouse)
Status
Unreviewed - Annotation score: 3 out of 5- Experimental evidence at transcript leveli
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    • History
      Entry version 96 (01 Oct 2014)
      Sequence version 1 (01 Jun 2001)
      Previous versions | rss
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    Functioni

    GO - Molecular functioni

    1. ATP binding Source: InterPro
    2. GTP binding Source: MGI
    3. GTP-dependent protein kinase activity Source: MGI
    4. protein binding Source: MGI

    GO - Biological processi

    1. negative regulation of GTPase activity Source: MGI
    2. protein autophosphorylation Source: MGI
    3. protein phosphorylation Source: MGI

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    Putative uncharacterized proteinImported
    Gene namesi
    Name:Lrrk2Imported
    OrganismiMus musculus (Mouse)Imported
    Taxonomic identifieri10090 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus

    Organism-specific databases

    MGIiMGI:1913975. Lrrk2.

    Subcellular locationi

    GO - Cellular componenti

    1. membrane raft Source: MGI
    2. plasma membrane Source: MGI
    3. synapse Source: MGI
    4. synaptic vesicle Source: MGI
    5. trans-Golgi network Source: MGI

    Expressioni

    Gene expression databases

    GenevestigatoriQ9CQG8.

    Family & Domainsi

    Phylogenomic databases

    HOVERGENiHBG075871.
    KOiK08844.

    Family and domain databases

    Gene3Di2.130.10.10. 1 hit.
    InterProiIPR011009. Kinase-like_dom.
    IPR000719. Prot_kinase_dom.
    IPR008271. Ser/Thr_kinase_AS.
    IPR015943. WD40/YVTN_repeat-like_dom.
    IPR001680. WD40_repeat.
    IPR017986. WD40_repeat_dom.
    [Graphical view]
    PfamiPF00069. Pkinase. 1 hit.
    [Graphical view]
    SMARTiSM00320. WD40. 2 hits.
    [Graphical view]
    SUPFAMiSSF50978. SSF50978. 1 hit.
    SSF56112. SSF56112. 1 hit.
    PROSITEiPS50011. PROTEIN_KINASE_DOM. 1 hit.
    PS00108. PROTEIN_KINASE_ST. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q9CQG8-1 [UniParc]FASTAAdd to Basket

    « Hide

    MLGAIFERPI PPDTRPWYLH SAMIIYRDLK PHNVLLFTLY PNAAIIAKIA    50
    DYGIAQYCCR MGIKTSEGTP GFRAPEVARG NVIYNQQADV YSFGLLLHDI 100
    WTTGSRIMEG LRFPNEFDEL AIQGKLPDPV KEYGCAPWPM VEKLITKCLK 150
    ENPQERPTSA QVFDILNSAE LICLMRHILI PKNIIVECMV ATNLNSKSAT 200
    LWLGCGNTEK GQLSLFDLNT ERYSYEEVAD SRILCLALVH LAAEKESWVV 250
    CGTQSGALLV INVEEETKRH TLEKMTDSVT CLHCNSLAKQ SKQSNFLLVG 300
    TADGNLMIFE DKAVKCKGAA PLKTLHIGDV STPLMCLSES LNSSERHITW 350
    GGCGTKVFSF SNDFTIQKLI ETKTNQLFSY AAFSDSNIIA LAVDTALYIA 400
    KKNSPVVEVW DKKTEKLCEL IDCVHFLKEV MVKLNKESKH QLSYSGRVKA 450
    LCLQKNTALW IGTGGGHILL LDLSTRRVIR TIHNFCDSVR AMATAQLGSL 500
    KNVMLVLGYK RKSTEGIQEQ KEIQSCLSIW DLNLPHEVQN LEKHIEVRTE 550
    LADKMRKTSV E 561
    Length:561
    Mass (Da):62,834
    Last modified:June 1, 2001 - v1
    Checksum:i8EB2B26C99F1D293
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AK014886 mRNA. Translation: BAB29603.1.
    AK014938 mRNA. Translation: BAB29628.1.
    RefSeqiNP_080006.3. NM_025730.3.
    UniGeneiMm.37558.

    Genome annotation databases

    GeneIDi66725.
    KEGGimmu:66725.
    UCSCiuc007xia.1. mouse.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AK014886 mRNA. Translation: BAB29603.1 .
    AK014938 mRNA. Translation: BAB29628.1 .
    RefSeqi NP_080006.3. NM_025730.3.
    UniGenei Mm.37558.

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    GeneIDi 66725.
    KEGGi mmu:66725.
    UCSCi uc007xia.1. mouse.

    Organism-specific databases

    CTDi 120892.
    MGIi MGI:1913975. Lrrk2.

    Phylogenomic databases

    HOVERGENi HBG075871.
    KOi K08844.

    Miscellaneous databases

    NextBioi 322485.
    SOURCEi Search...

    Gene expression databases

    Genevestigatori Q9CQG8.

    Family and domain databases

    Gene3Di 2.130.10.10. 1 hit.
    InterProi IPR011009. Kinase-like_dom.
    IPR000719. Prot_kinase_dom.
    IPR008271. Ser/Thr_kinase_AS.
    IPR015943. WD40/YVTN_repeat-like_dom.
    IPR001680. WD40_repeat.
    IPR017986. WD40_repeat_dom.
    [Graphical view ]
    Pfami PF00069. Pkinase. 1 hit.
    [Graphical view ]
    SMARTi SM00320. WD40. 2 hits.
    [Graphical view ]
    SUPFAMi SSF50978. SSF50978. 1 hit.
    SSF56112. SSF56112. 1 hit.
    PROSITEi PS50011. PROTEIN_KINASE_DOM. 1 hit.
    PS00108. PROTEIN_KINASE_ST. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "High-efficiency full-length cDNA cloning."
      Carninci P., Hayashizaki Y.
      Methods Enzymol. 303:19-44(1999) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE.
      Strain: C57BL/6JImported.
      Tissue: TestisImported.
    2. "Normalization and subtraction of cap-trapper-selected cDNAs to prepare full-length cDNA libraries for rapid discovery of new genes."
      Carninci P., Shibata Y., Hayatsu N., Sugahara Y., Shibata K., Itoh M., Konno H., Okazaki Y., Muramatsu M., Hayashizaki Y.
      Genome Res. 10:1617-1630(2000) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE.
      Strain: C57BL/6JImported.
      Tissue: TestisImported.
    3. Cited for: NUCLEOTIDE SEQUENCE.
      Strain: C57BL/6JImported.
      Tissue: TestisImported.
    4. Cited for: NUCLEOTIDE SEQUENCE.
      Strain: C57BL/6JImported.
      Tissue: TestisImported.
    5. "Functional annotation of a full-length mouse cDNA collection."
      The RIKEN Genome Exploration Research Group Phase II Team and the FANTOM Consortium
      Nature 409:685-690(2001)
      Cited for: NUCLEOTIDE SEQUENCE.
      Strain: C57BL/6JImported.
      Tissue: TestisImported.
    6. "Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs."
      The FANTOM Consortium and the RIKEN Genome Exploration Research Group Phase I and II Team
      Nature 420:563-573(2002)
      Cited for: NUCLEOTIDE SEQUENCE.
      Strain: C57BL/6JImported.
      Tissue: TestisImported.
    7. "The Transcriptional Landscape of the Mammalian Genome."
      The FANTOM Consortium, Riken Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group)
      Science 309:1559-1563(2005)
      Cited for: NUCLEOTIDE SEQUENCE.
      Strain: C57BL/6JImported.
      Tissue: TestisImported.
    8. Cited for: NUCLEOTIDE SEQUENCE.
      Strain: C57BL/6JImported.
      Tissue: TestisImported.

    Entry informationi

    Entry nameiQ9CQG8_MOUSE
    AccessioniPrimary (citable) accession number: Q9CQG8
    Entry historyi
    Integrated into UniProtKB/TrEMBL: June 1, 2001
    Last sequence update: June 1, 2001
    Last modified: October 1, 2014
    This is version 96 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)