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Protein
Submitted name:

Putative uncharacterized protein

Gene

Lrrk2

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: Annotation score: 5 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
Putative uncharacterized proteinImported
Gene namesi
Name:Lrrk2Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus

Organism-specific databases

MGIiMGI:1913975. Lrrk2.

Subcellular locationi

GO - Cellular componenti

  • axon Source: MGI
  • cytoplasm Source: MGI
  • cytoplasmic side of mitochondrial outer membrane Source: MGI
  • cytosol Source: MGI
  • dendrite Source: MGI
  • dendrite cytoplasm Source: MGI
  • extracellular exosome Source: MGI
  • extracellular space Source: MGI
  • inclusion body Source: MGI
  • membrane raft Source: MGI
  • mitochondrial membrane Source: MGI
  • mitochondrion Source: MGI
  • neuronal cell body Source: MGI
  • neuron projection Source: MGI
  • perikaryon Source: MGI
  • plasma membrane Source: MGI
  • ribonucleoprotein complex Source: MGI
  • synapse Source: MGI
  • synaptic vesicle Source: MGI
  • trans-Golgi network Source: MGI
Complete GO annotation...

Interactioni

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000052584.

Family & Domainsi

Phylogenomic databases

HOVERGENiHBG075871.
KOiK08844.

Family and domain databases

Gene3Di2.130.10.10. 1 hit.
InterProiIPR011009. Kinase-like_dom.
IPR000719. Prot_kinase_dom.
IPR008271. Ser/Thr_kinase_AS.
IPR015943. WD40/YVTN_repeat-like_dom.
IPR001680. WD40_repeat.
IPR017986. WD40_repeat_dom.
[Graphical view]
PfamiPF00069. Pkinase. 1 hit.
[Graphical view]
SMARTiSM00320. WD40. 2 hits.
[Graphical view]
SUPFAMiSSF50978. SSF50978. 1 hit.
SSF56112. SSF56112. 1 hit.
PROSITEiPS50011. PROTEIN_KINASE_DOM. 1 hit.
PS00108. PROTEIN_KINASE_ST. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q9CQG8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MLGAIFERPI PPDTRPWYLH SAMIIYRDLK PHNVLLFTLY PNAAIIAKIA
60 70 80 90 100
DYGIAQYCCR MGIKTSEGTP GFRAPEVARG NVIYNQQADV YSFGLLLHDI
110 120 130 140 150
WTTGSRIMEG LRFPNEFDEL AIQGKLPDPV KEYGCAPWPM VEKLITKCLK
160 170 180 190 200
ENPQERPTSA QVFDILNSAE LICLMRHILI PKNIIVECMV ATNLNSKSAT
210 220 230 240 250
LWLGCGNTEK GQLSLFDLNT ERYSYEEVAD SRILCLALVH LAAEKESWVV
260 270 280 290 300
CGTQSGALLV INVEEETKRH TLEKMTDSVT CLHCNSLAKQ SKQSNFLLVG
310 320 330 340 350
TADGNLMIFE DKAVKCKGAA PLKTLHIGDV STPLMCLSES LNSSERHITW
360 370 380 390 400
GGCGTKVFSF SNDFTIQKLI ETKTNQLFSY AAFSDSNIIA LAVDTALYIA
410 420 430 440 450
KKNSPVVEVW DKKTEKLCEL IDCVHFLKEV MVKLNKESKH QLSYSGRVKA
460 470 480 490 500
LCLQKNTALW IGTGGGHILL LDLSTRRVIR TIHNFCDSVR AMATAQLGSL
510 520 530 540 550
KNVMLVLGYK RKSTEGIQEQ KEIQSCLSIW DLNLPHEVQN LEKHIEVRTE
560
LADKMRKTSV E
Length:561
Mass (Da):62,834
Last modified:June 1, 2001 - v1
Checksum:i8EB2B26C99F1D293
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK014886 mRNA. Translation: BAB29603.1.
AK014938 mRNA. Translation: BAB29628.1.
RefSeqiNP_080006.3. NM_025730.3.
UniGeneiMm.37558.

Genome annotation databases

GeneIDi66725.
KEGGimmu:66725.
UCSCiuc007xia.1. mouse.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK014886 mRNA. Translation: BAB29603.1.
AK014938 mRNA. Translation: BAB29628.1.
RefSeqiNP_080006.3. NM_025730.3.
UniGeneiMm.37558.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000052584.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi66725.
KEGGimmu:66725.
UCSCiuc007xia.1. mouse.

Organism-specific databases

CTDi120892.
MGIiMGI:1913975. Lrrk2.

Phylogenomic databases

HOVERGENiHBG075871.
KOiK08844.

Miscellaneous databases

NextBioi322485.
SOURCEiSearch...

Family and domain databases

Gene3Di2.130.10.10. 1 hit.
InterProiIPR011009. Kinase-like_dom.
IPR000719. Prot_kinase_dom.
IPR008271. Ser/Thr_kinase_AS.
IPR015943. WD40/YVTN_repeat-like_dom.
IPR001680. WD40_repeat.
IPR017986. WD40_repeat_dom.
[Graphical view]
PfamiPF00069. Pkinase. 1 hit.
[Graphical view]
SMARTiSM00320. WD40. 2 hits.
[Graphical view]
SUPFAMiSSF50978. SSF50978. 1 hit.
SSF56112. SSF56112. 1 hit.
PROSITEiPS50011. PROTEIN_KINASE_DOM. 1 hit.
PS00108. PROTEIN_KINASE_ST. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "High-efficiency full-length cDNA cloning."
    Carninci P., Hayashizaki Y.
    Methods Enzymol. 303:19-44(1999) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
    Tissue: TestisImported.
  2. "Normalization and subtraction of cap-trapper-selected cDNAs to prepare full-length cDNA libraries for rapid discovery of new genes."
    Carninci P., Shibata Y., Hayatsu N., Sugahara Y., Shibata K., Itoh M., Konno H., Okazaki Y., Muramatsu M., Hayashizaki Y.
    Genome Res. 10:1617-1630(2000) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
    Tissue: TestisImported.
  3. Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
    Tissue: TestisImported.
  4. Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
    Tissue: TestisImported.
  5. "Functional annotation of a full-length mouse cDNA collection."
    The RIKEN Genome Exploration Research Group Phase II Team and the FANTOM Consortium
    Nature 409:685-690(2001)
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
    Tissue: TestisImported.
  6. "Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs."
    The FANTOM Consortium and the RIKEN Genome Exploration Research Group Phase I and II Team
    Nature 420:563-573(2002)
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
    Tissue: TestisImported.
  7. "The Transcriptional Landscape of the Mammalian Genome."
    The FANTOM Consortium, Riken Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group)
    Science 309:1559-1563(2005)
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
    Tissue: TestisImported.
  8. Cited for: NUCLEOTIDE SEQUENCE.
    Strain: C57BL/6JImported.
    Tissue: TestisImported.

Entry informationi

Entry nameiQ9CQG8_MOUSE
AccessioniPrimary (citable) accession number: Q9CQG8
Entry historyi
Integrated into UniProtKB/TrEMBL: June 1, 2001
Last sequence update: June 1, 2001
Last modified: June 24, 2015
This is version 103 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.