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Protein

39S ribosomal protein L11, mitochondrial

Gene

Mrpl11

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

  1. poly(A) RNA binding Source: MGI
  2. structural constituent of ribosome Source: MGI

GO - Biological processi

  1. translation Source: MGI
Complete GO annotation...

Keywords - Molecular functioni

Ribonucleoprotein, Ribosomal protein

Enzyme and pathway databases

ReactomeiREACT_270125. Mitochondrial translation elongation.
REACT_270158. Mitochondrial translation termination.
REACT_271096. Mitochondrial translation initiation.

Names & Taxonomyi

Protein namesi
Recommended name:
39S ribosomal protein L11, mitochondrial
Short name:
L11mt
Short name:
MRP-L11
Gene namesi
Name:Mrpl11
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
ProteomesiUP000000589: Chromosome 19

Organism-specific databases

MGIiMGI:2137215. Mrpl11.

Subcellular locationi

Mitochondrion 1 Publication

GO - Cellular componenti

  1. mitochondrial large ribosomal subunit Source: MGI
  2. mitochondrion Source: MGI
Complete GO annotation...

Keywords - Cellular componenti

Mitochondrion

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini? – 19239S ribosomal protein L11, mitochondrialPRO_0000030444
Transit peptidei1 – ?MitochondrionSequence Analysis

Proteomic databases

MaxQBiQ9CQF0.
PaxDbiQ9CQF0.
PRIDEiQ9CQF0.

PTM databases

PhosphoSiteiQ9CQF0.

Expressioni

Gene expression databases

BgeeiQ9CQF0.
CleanExiMM_MRPL11.
GenevestigatoriQ9CQF0.

Interactioni

Protein-protein interaction databases

BioGridi211460. 7 interactions.

Structurei

3D structure databases

ProteinModelPortaliQ9CQF0.
SMRiQ9CQF0. Positions 24-155.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the ribosomal protein L11P family.Curated

Keywords - Domaini

Transit peptide

Phylogenomic databases

eggNOGiCOG0080.
GeneTreeiENSGT00390000003153.
HOGENOMiHOG000082123.
HOVERGENiHBG036110.
InParanoidiQ9CQF0.
KOiK02867.
OMAiCKDFNER.
OrthoDBiEOG7HHWTP.
PhylomeDBiQ9CQF0.
TreeFamiTF313471.

Family and domain databases

Gene3Di1.10.10.250. 1 hit.
3.30.1550.10. 1 hit.
HAMAPiMF_00736. Ribosomal_L11.
InterProiIPR000911. Ribosomal_L11/L12.
IPR006519. Ribosomal_L11_bac-typ.
IPR020783. Ribosomal_L11_C.
IPR020784. Ribosomal_L11_N.
[Graphical view]
PANTHERiPTHR11661. PTHR11661. 1 hit.
PfamiPF00298. Ribosomal_L11. 1 hit.
PF03946. Ribosomal_L11_N. 1 hit.
[Graphical view]
SMARTiSM00649. RL11. 1 hit.
[Graphical view]
SUPFAMiSSF46906. SSF46906. 1 hit.
SSF54747. SSF54747. 1 hit.
TIGRFAMsiTIGR01632. L11_bact. 1 hit.

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q9CQF0-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSKLSRATRT LKKPEAGGVI RSIVRAGQAI PGPPLGPILG QRGVSINQFC
60 70 80 90 100
KEFNEKTKDI KEGIPLPTKI FIKPDRTFEL KIGQPTVSYF LKAAAGIEKG
110 120 130 140 150
ARHTGKEVAG LVSLKHVYEI ACVKAKDDAF AMQDVPLSSV VRSIIGSARS
160 170 180 190
LGIRVVKDLS AEELEAFQKE RAVFLAAQKE ADLAAQAEAA KK
Length:192
Mass (Da):20,680
Last modified:June 1, 2001 - v1
Checksum:i9530EFA4E41A81F3
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB049639 mRNA. Translation: BAB40844.1.
AK002797 mRNA. Translation: BAB22366.1.
AK010329 mRNA. Translation: BAB26856.1.
AK167247 mRNA. Translation: BAE39368.1.
BC046750 mRNA. Translation: AAH46750.1.
CCDSiCCDS29444.1.
RefSeqiNP_079829.1. NM_025553.4.
UniGeneiMm.28494.

Genome annotation databases

EnsembliENSMUST00000025836; ENSMUSP00000025836; ENSMUSG00000024902.
GeneIDi66419.
KEGGimmu:66419.
UCSCiuc008gbt.2. mouse.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB049639 mRNA. Translation: BAB40844.1.
AK002797 mRNA. Translation: BAB22366.1.
AK010329 mRNA. Translation: BAB26856.1.
AK167247 mRNA. Translation: BAE39368.1.
BC046750 mRNA. Translation: AAH46750.1.
CCDSiCCDS29444.1.
RefSeqiNP_079829.1. NM_025553.4.
UniGeneiMm.28494.

3D structure databases

ProteinModelPortaliQ9CQF0.
SMRiQ9CQF0. Positions 24-155.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi211460. 7 interactions.

PTM databases

PhosphoSiteiQ9CQF0.

Proteomic databases

MaxQBiQ9CQF0.
PaxDbiQ9CQF0.
PRIDEiQ9CQF0.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000025836; ENSMUSP00000025836; ENSMUSG00000024902.
GeneIDi66419.
KEGGimmu:66419.
UCSCiuc008gbt.2. mouse.

Organism-specific databases

CTDi65003.
MGIiMGI:2137215. Mrpl11.

Phylogenomic databases

eggNOGiCOG0080.
GeneTreeiENSGT00390000003153.
HOGENOMiHOG000082123.
HOVERGENiHBG036110.
InParanoidiQ9CQF0.
KOiK02867.
OMAiCKDFNER.
OrthoDBiEOG7HHWTP.
PhylomeDBiQ9CQF0.
TreeFamiTF313471.

Enzyme and pathway databases

ReactomeiREACT_270125. Mitochondrial translation elongation.
REACT_270158. Mitochondrial translation termination.
REACT_271096. Mitochondrial translation initiation.

Miscellaneous databases

NextBioi321635.
PROiQ9CQF0.
SOURCEiSearch...

Gene expression databases

BgeeiQ9CQF0.
CleanExiMM_MRPL11.
GenevestigatoriQ9CQF0.

Family and domain databases

Gene3Di1.10.10.250. 1 hit.
3.30.1550.10. 1 hit.
HAMAPiMF_00736. Ribosomal_L11.
InterProiIPR000911. Ribosomal_L11/L12.
IPR006519. Ribosomal_L11_bac-typ.
IPR020783. Ribosomal_L11_C.
IPR020784. Ribosomal_L11_N.
[Graphical view]
PANTHERiPTHR11661. PTHR11661. 1 hit.
PfamiPF00298. Ribosomal_L11. 1 hit.
PF03946. Ribosomal_L11_N. 1 hit.
[Graphical view]
SMARTiSM00649. RL11. 1 hit.
[Graphical view]
SUPFAMiSSF46906. SSF46906. 1 hit.
SSF54747. SSF54747. 1 hit.
TIGRFAMsiTIGR01632. L11_bact. 1 hit.
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. "Structural compensation for the deficit of rRNA with proteins in the mammalian mitochondrial ribosome. Systematic analysis of protein components of the large ribosomal subunit from mammalian mitochondria."
    Suzuki T., Terasaki M., Takemoto-Hori C., Hanada T., Ueda T., Wada A., Watanabe K.
    J. Biol. Chem. 276:21724-21736(2001) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [MRNA], SUBCELLULAR LOCATION.
  2. "The transcriptional landscape of the mammalian genome."
    Carninci P., Kasukawa T., Katayama S., Gough J., Frith M.C., Maeda N., Oyama R., Ravasi T., Lenhard B., Wells C., Kodzius R., Shimokawa K., Bajic V.B., Brenner S.E., Batalov S., Forrest A.R., Zavolan M., Davis M.J.
    , Wilming L.G., Aidinis V., Allen J.E., Ambesi-Impiombato A., Apweiler R., Aturaliya R.N., Bailey T.L., Bansal M., Baxter L., Beisel K.W., Bersano T., Bono H., Chalk A.M., Chiu K.P., Choudhary V., Christoffels A., Clutterbuck D.R., Crowe M.L., Dalla E., Dalrymple B.P., de Bono B., Della Gatta G., di Bernardo D., Down T., Engstrom P., Fagiolini M., Faulkner G., Fletcher C.F., Fukushima T., Furuno M., Futaki S., Gariboldi M., Georgii-Hemming P., Gingeras T.R., Gojobori T., Green R.E., Gustincich S., Harbers M., Hayashi Y., Hensch T.K., Hirokawa N., Hill D., Huminiecki L., Iacono M., Ikeo K., Iwama A., Ishikawa T., Jakt M., Kanapin A., Katoh M., Kawasawa Y., Kelso J., Kitamura H., Kitano H., Kollias G., Krishnan S.P., Kruger A., Kummerfeld S.K., Kurochkin I.V., Lareau L.F., Lazarevic D., Lipovich L., Liu J., Liuni S., McWilliam S., Madan Babu M., Madera M., Marchionni L., Matsuda H., Matsuzawa S., Miki H., Mignone F., Miyake S., Morris K., Mottagui-Tabar S., Mulder N., Nakano N., Nakauchi H., Ng P., Nilsson R., Nishiguchi S., Nishikawa S., Nori F., Ohara O., Okazaki Y., Orlando V., Pang K.C., Pavan W.J., Pavesi G., Pesole G., Petrovsky N., Piazza S., Reed J., Reid J.F., Ring B.Z., Ringwald M., Rost B., Ruan Y., Salzberg S.L., Sandelin A., Schneider C., Schoenbach C., Sekiguchi K., Semple C.A., Seno S., Sessa L., Sheng Y., Shibata Y., Shimada H., Shimada K., Silva D., Sinclair B., Sperling S., Stupka E., Sugiura K., Sultana R., Takenaka Y., Taki K., Tammoja K., Tan S.L., Tang S., Taylor M.S., Tegner J., Teichmann S.A., Ueda H.R., van Nimwegen E., Verardo R., Wei C.L., Yagi K., Yamanishi H., Zabarovsky E., Zhu S., Zimmer A., Hide W., Bult C., Grimmond S.M., Teasdale R.D., Liu E.T., Brusic V., Quackenbush J., Wahlestedt C., Mattick J.S., Hume D.A., Kai C., Sasaki D., Tomaru Y., Fukuda S., Kanamori-Katayama M., Suzuki M., Aoki J., Arakawa T., Iida J., Imamura K., Itoh M., Kato T., Kawaji H., Kawagashira N., Kawashima T., Kojima M., Kondo S., Konno H., Nakano K., Ninomiya N., Nishio T., Okada M., Plessy C., Shibata K., Shiraki T., Suzuki S., Tagami M., Waki K., Watahiki A., Okamura-Oho Y., Suzuki H., Kawai J., Hayashizaki Y.
    Science 309:1559-1563(2005) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Strain: C57BL/6J.
    Tissue: Embryonic stem cell and Kidney.
  3. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Strain: C57BL/6.
    Tissue: Brain.

Entry informationi

Entry nameiRM11_MOUSE
AccessioniPrimary (citable) accession number: Q9CQF0
Secondary accession number(s): Q3TJX7
Entry historyi
Integrated into UniProtKB/Swiss-Prot: July 26, 2002
Last sequence update: June 1, 2001
Last modified: February 4, 2015
This is version 107 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
  2. Ribosomal proteins
    Ribosomal proteins families and list of entries
  3. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.