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Protein

Protein NipSnap homolog 3B

Gene

Nipsnap3b

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Names & Taxonomyi

Protein namesi
Recommended name:
Protein NipSnap homolog 3B
Short name:
NipSnap3B
Alternative name(s):
NipSnap-related protein
Protein NipSnap homolog 3A
Short name:
NipSnap3A
Gene namesi
Name:Nipsnap3b
Synonyms:Nipsnap3a
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 4

Organism-specific databases

MGIiMGI:1913786. Nipsnap3b.

Subcellular locationi

  • Cytoplasmcytosol

  • Note: May be part of some vesicular structure distinct from lysosomal vesicles.By similarity

GO - Cellular componenti

  • cytosol Source: UniProtKB-SubCell
  • mitochondrion Source: MGI
  • nucleus Source: MGI
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 247247Protein NipSnap homolog 3BPRO_0000221155Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei45 – 451N6-succinyllysineCombined sources
Modified residuei48 – 481N6-succinyllysineCombined sources
Modified residuei57 – 571N6-succinyllysineCombined sources
Modified residuei166 – 1661N6-succinyllysineCombined sources

Proteomic databases

EPDiQ9CQE1.
MaxQBiQ9CQE1.
PaxDbiQ9CQE1.
PRIDEiQ9CQE1.

PTM databases

iPTMnetiQ9CQE1.
PhosphoSiteiQ9CQE1.

Expressioni

Gene expression databases

BgeeiQ9CQE1.
CleanExiMM_NIPSNAP3A.
ExpressionAtlasiQ9CQE1. baseline and differential.
GenevisibleiQ9CQE1. MM.

Interactioni

Protein-protein interaction databases

IntActiQ9CQE1. 1 interaction.
MINTiMINT-1860977.
STRINGi10090.ENSMUSP00000015391.

Structurei

3D structure databases

ProteinModelPortaliQ9CQE1.
SMRiQ9CQE1. Positions 180-247.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the NipSnap family.Curated

Phylogenomic databases

eggNOGiKOG2883. Eukaryota.
ENOG410XSWP. LUCA.
GeneTreeiENSGT00730000111003.
HOGENOMiHOG000007437.
HOVERGENiHBG052660.
InParanoidiQ9CQE1.
OMAiLWGDAFR.
OrthoDBiEOG776SQT.
PhylomeDBiQ9CQE1.
TreeFamiTF314501.

Family and domain databases

InterProiIPR011008. Dimeric_a/b-barrel.
IPR012577. NIPSNAP.
[Graphical view]
PfamiPF07978. NIPSNAP. 2 hits.
[Graphical view]
SUPFAMiSSF54909. SSF54909. 2 hits.

Sequencei

Sequence statusi: Complete.

Q9CQE1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MLALRSGLRT ALAPRVLTPQ VCSPFATGPR QSNGTFYEFR TYFLKPSKTN
60 70 80 90 100
EFLENFKNSV HLRTAHSEMI GYWTVEFGGR TNRVFHIWKY DNFAHRTAVR
110 120 130 140 150
KALAKDKEWQ ERFLIPNLAF IDKQEVEITY LVPWCKIGTP PKEGVYELAT
160 170 180 190 200
FQMKPGGPAL WGNAFKRAVN AHVELGYSTL VGVFHTEYGA LNRVHVLWWN
210 220 230 240
ESADSRAAGR HWSHEDPRVV AAVRESVSYL ESQQNTFLIP TSFSPLK
Length:247
Mass (Da):28,308
Last modified:June 1, 2001 - v1
Checksum:i99791350D557956C
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sequence conflicti5 – 51R → L in AAL56225 (Ref. 1) Curated
Sequence conflicti33 – 331N → D in AAL56225 (Ref. 1) Curated
Sequence conflicti36 – 361F → L in AAL56225 (Ref. 1) Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF353623 mRNA. Translation: AAL56225.1.
AK004458 mRNA. Translation: BAB23312.1.
AK008786 mRNA. Translation: BAB25894.1.
AK012480 mRNA. Translation: BAB28269.1.
AL772397 Genomic DNA. Translation: CAM27442.1.
CH466565 Genomic DNA. Translation: EDL02287.1.
BC019505 mRNA. Translation: AAH19505.1.
CCDSiCCDS18186.1.
RefSeqiNP_079899.1. NM_025623.2.
UniGeneiMm.38244.

Genome annotation databases

EnsembliENSMUST00000015391; ENSMUSP00000015391; ENSMUSG00000015247.
GeneIDi66536.
KEGGimmu:66536.
UCSCiuc008swt.1. mouse.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AF353623 mRNA. Translation: AAL56225.1.
AK004458 mRNA. Translation: BAB23312.1.
AK008786 mRNA. Translation: BAB25894.1.
AK012480 mRNA. Translation: BAB28269.1.
AL772397 Genomic DNA. Translation: CAM27442.1.
CH466565 Genomic DNA. Translation: EDL02287.1.
BC019505 mRNA. Translation: AAH19505.1.
CCDSiCCDS18186.1.
RefSeqiNP_079899.1. NM_025623.2.
UniGeneiMm.38244.

3D structure databases

ProteinModelPortaliQ9CQE1.
SMRiQ9CQE1. Positions 180-247.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

IntActiQ9CQE1. 1 interaction.
MINTiMINT-1860977.
STRINGi10090.ENSMUSP00000015391.

PTM databases

iPTMnetiQ9CQE1.
PhosphoSiteiQ9CQE1.

Proteomic databases

EPDiQ9CQE1.
MaxQBiQ9CQE1.
PaxDbiQ9CQE1.
PRIDEiQ9CQE1.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000015391; ENSMUSP00000015391; ENSMUSG00000015247.
GeneIDi66536.
KEGGimmu:66536.
UCSCiuc008swt.1. mouse.

Organism-specific databases

CTDi55335.
MGIiMGI:1913786. Nipsnap3b.

Phylogenomic databases

eggNOGiKOG2883. Eukaryota.
ENOG410XSWP. LUCA.
GeneTreeiENSGT00730000111003.
HOGENOMiHOG000007437.
HOVERGENiHBG052660.
InParanoidiQ9CQE1.
OMAiLWGDAFR.
OrthoDBiEOG776SQT.
PhylomeDBiQ9CQE1.
TreeFamiTF314501.

Miscellaneous databases

NextBioi321966.
PROiQ9CQE1.
SOURCEiSearch...

Gene expression databases

BgeeiQ9CQE1.
CleanExiMM_NIPSNAP3A.
ExpressionAtlasiQ9CQE1. baseline and differential.
GenevisibleiQ9CQE1. MM.

Family and domain databases

InterProiIPR011008. Dimeric_a/b-barrel.
IPR012577. NIPSNAP.
[Graphical view]
PfamiPF07978. NIPSNAP. 2 hits.
[Graphical view]
SUPFAMiSSF54909. SSF54909. 2 hits.
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. "Cloning and characterization of a novel NIPSNAP-related protein."
    Shaw D.J., Carrello A., Ward B.K., Temple S.E., Mark P.J., Minchin R.F., Ratajczak T.
    Submitted (FEB-2001) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [MRNA].
  2. "The transcriptional landscape of the mammalian genome."
    Carninci P., Kasukawa T., Katayama S., Gough J., Frith M.C., Maeda N., Oyama R., Ravasi T., Lenhard B., Wells C., Kodzius R., Shimokawa K., Bajic V.B., Brenner S.E., Batalov S., Forrest A.R., Zavolan M., Davis M.J.
    , Wilming L.G., Aidinis V., Allen J.E., Ambesi-Impiombato A., Apweiler R., Aturaliya R.N., Bailey T.L., Bansal M., Baxter L., Beisel K.W., Bersano T., Bono H., Chalk A.M., Chiu K.P., Choudhary V., Christoffels A., Clutterbuck D.R., Crowe M.L., Dalla E., Dalrymple B.P., de Bono B., Della Gatta G., di Bernardo D., Down T., Engstrom P., Fagiolini M., Faulkner G., Fletcher C.F., Fukushima T., Furuno M., Futaki S., Gariboldi M., Georgii-Hemming P., Gingeras T.R., Gojobori T., Green R.E., Gustincich S., Harbers M., Hayashi Y., Hensch T.K., Hirokawa N., Hill D., Huminiecki L., Iacono M., Ikeo K., Iwama A., Ishikawa T., Jakt M., Kanapin A., Katoh M., Kawasawa Y., Kelso J., Kitamura H., Kitano H., Kollias G., Krishnan S.P., Kruger A., Kummerfeld S.K., Kurochkin I.V., Lareau L.F., Lazarevic D., Lipovich L., Liu J., Liuni S., McWilliam S., Madan Babu M., Madera M., Marchionni L., Matsuda H., Matsuzawa S., Miki H., Mignone F., Miyake S., Morris K., Mottagui-Tabar S., Mulder N., Nakano N., Nakauchi H., Ng P., Nilsson R., Nishiguchi S., Nishikawa S., Nori F., Ohara O., Okazaki Y., Orlando V., Pang K.C., Pavan W.J., Pavesi G., Pesole G., Petrovsky N., Piazza S., Reed J., Reid J.F., Ring B.Z., Ringwald M., Rost B., Ruan Y., Salzberg S.L., Sandelin A., Schneider C., Schoenbach C., Sekiguchi K., Semple C.A., Seno S., Sessa L., Sheng Y., Shibata Y., Shimada H., Shimada K., Silva D., Sinclair B., Sperling S., Stupka E., Sugiura K., Sultana R., Takenaka Y., Taki K., Tammoja K., Tan S.L., Tang S., Taylor M.S., Tegner J., Teichmann S.A., Ueda H.R., van Nimwegen E., Verardo R., Wei C.L., Yagi K., Yamanishi H., Zabarovsky E., Zhu S., Zimmer A., Hide W., Bult C., Grimmond S.M., Teasdale R.D., Liu E.T., Brusic V., Quackenbush J., Wahlestedt C., Mattick J.S., Hume D.A., Kai C., Sasaki D., Tomaru Y., Fukuda S., Kanamori-Katayama M., Suzuki M., Aoki J., Arakawa T., Iida J., Imamura K., Itoh M., Kato T., Kawaji H., Kawagashira N., Kawashima T., Kojima M., Kondo S., Konno H., Nakano K., Ninomiya N., Nishio T., Okada M., Plessy C., Shibata K., Shiraki T., Suzuki S., Tagami M., Waki K., Watahiki A., Okamura-Oho Y., Suzuki H., Kawai J., Hayashizaki Y.
    Science 309:1559-1563(2005) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Strain: C57BL/6J.
    Tissue: Embryo and Stomach.
  3. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: C57BL/6J.
  4. Mural R.J., Adams M.D., Myers E.W., Smith H.O., Venter J.C.
    Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
  5. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Tissue: Salivary gland.
  6. Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
    Tissue: Brain, Brown adipose tissue, Heart, Kidney, Liver, Lung, Spleen and Testis.
  7. "SIRT5-mediated lysine desuccinylation impacts diverse metabolic pathways."
    Park J., Chen Y., Tishkoff D.X., Peng C., Tan M., Dai L., Xie Z., Zhang Y., Zwaans B.M., Skinner M.E., Lombard D.B., Zhao Y.
    Mol. Cell 50:919-930(2013) [PubMed] [Europe PMC] [Abstract]
    Cited for: SUCCINYLATION [LARGE SCALE ANALYSIS] AT LYS-45; LYS-48; LYS-57 AND LYS-166, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
    Tissue: Embryonic fibroblast and Liver.

Entry informationi

Entry nameiNPS3B_MOUSE
AccessioniPrimary (citable) accession number: Q9CQE1
Secondary accession number(s): B1AWZ4, Q8VHX9
Entry historyi
Integrated into UniProtKB/Swiss-Prot: April 26, 2004
Last sequence update: June 1, 2001
Last modified: March 16, 2016
This is version 98 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.