Q9CQD6 (SARCO_MOUSE) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Sarcolipin

Gene names

Name:

Sln

Organism

Mus musculus (Mouse) [Reference proteome]

Taxonomic identifier

10090 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Metazoa › Eumetazoa › Bilateria › Deuterostomia › Chordata › Craniata › Vertebrata › Gnathostomata › Teleostomi › Euteleostomi › Sarcopterygii › Tetrapoda › Amniota › Mammalia › Theria › Eutheria › Euarchontoglires › Glires › Rodentia › Sciurognathi › Muroidea › Muridae › Murinae › Mus › Mus

Protein attributes

Sequence length	31 AA.
Sequence status	Complete.
Protein existence	Evidence at transcript level

General annotation (Comments)

Subunit structure	Associated with calcium ATPase SERCA1.
Subcellular location	Sarcoplasmic reticulum membrane; Single-pass membrane protein.
Sequence similarities	Belongs to the sarcolipin family.

Ontologies

Keywords
Cellular component	Membrane Sarcoplasmic reticulum
Domain	Transmembrane Transmembrane helix
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	regulation of calcium ion transport Inferred from sequence or structural similarity. Source: UniProtKB regulation of catalytic activity Inferred from electronic annotation. Source: GOC
Cellular_component	integral to membrane Inferred from electronic annotation. Source: UniProtKB-KW sarcoplasmic reticulum Inferred from sequence or structural similarity. Source: UniProtKB sarcoplasmic reticulum membrane Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular_function	enzyme regulator activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Peptide	1 – 31	31	Sarcolipin		PRO_0000045899
Regions
	Transmembrane	8 – 25	18	Helical; Potential

Sequences

	Sequence		Length	Mass (Da)
	Q9CQD6 [UniParc]. Last modified June 1, 2001. Version 1. Checksum: 9B310161575EF81D	FASTA	31	3,808
	10 20 30 MERSTQELFI NFTVVLITVL LMWLLVRSYQ Y

References

[1]	"The transcriptional landscape of the mammalian genome." Carninci P., Kasukawa T., Katayama S., Gough J., Frith M.C., Maeda N., Oyama R., Ravasi T., Lenhard B., Wells C., Kodzius R., Shimokawa K., Bajic V.B., Brenner S.E., Batalov S., Forrest A.R., Zavolan M., Davis M.J. , Wilming L.G., Aidinis V., Allen J.E., Ambesi-Impiombato A., Apweiler R., Aturaliya R.N., Bailey T.L., Bansal M., Baxter L., Beisel K.W., Bersano T., Bono H., Chalk A.M., Chiu K.P., Choudhary V., Christoffels A., Clutterbuck D.R., Crowe M.L., Dalla E., Dalrymple B.P., de Bono B., Della Gatta G., di Bernardo D., Down T., Engstrom P., Fagiolini M., Faulkner G., Fletcher C.F., Fukushima T., Furuno M., Futaki S., Gariboldi M., Georgii-Hemming P., Gingeras T.R., Gojobori T., Green R.E., Gustincich S., Harbers M., Hayashi Y., Hensch T.K., Hirokawa N., Hill D., Huminiecki L., Iacono M., Ikeo K., Iwama A., Ishikawa T., Jakt M., Kanapin A., Katoh M., Kawasawa Y., Kelso J., Kitamura H., Kitano H., Kollias G., Krishnan S.P., Kruger A., Kummerfeld S.K., Kurochkin I.V., Lareau L.F., Lazarevic D., Lipovich L., Liu J., Liuni S., McWilliam S., Madan Babu M., Madera M., Marchionni L., Matsuda H., Matsuzawa S., Miki H., Mignone F., Miyake S., Morris K., Mottagui-Tabar S., Mulder N., Nakano N., Nakauchi H., Ng P., Nilsson R., Nishiguchi S., Nishikawa S., Nori F., Ohara O., Okazaki Y., Orlando V., Pang K.C., Pavan W.J., Pavesi G., Pesole G., Petrovsky N., Piazza S., Reed J., Reid J.F., Ring B.Z., Ringwald M., Rost B., Ruan Y., Salzberg S.L., Sandelin A., Schneider C., Schoenbach C., Sekiguchi K., Semple C.A., Seno S., Sessa L., Sheng Y., Shibata Y., Shimada H., Shimada K., Silva D., Sinclair B., Sperling S., Stupka E., Sugiura K., Sultana R., Takenaka Y., Taki K., Tammoja K., Tan S.L., Tang S., Taylor M.S., Tegner J., Teichmann S.A., Ueda H.R., van Nimwegen E., Verardo R., Wei C.L., Yagi K., Yamanishi H., Zabarovsky E., Zhu S., Zimmer A., Hide W., Bult C., Grimmond S.M., Teasdale R.D., Liu E.T., Brusic V., Quackenbush J., Wahlestedt C., Mattick J.S., Hume D.A., Kai C., Sasaki D., Tomaru Y., Fukuda S., Kanamori-Katayama M., Suzuki M., Aoki J., Arakawa T., Iida J., Imamura K., Itoh M., Kato T., Kawaji H., Kawagashira N., Kawashima T., Kojima M., Kondo S., Konno H., Nakano K., Ninomiya N., Nishio T., Okada M., Plessy C., Shibata K., Shiraki T., Suzuki S., Tagami M., Waki K., Watahiki A., Okamura-Oho Y., Suzuki H., Kawai J., Hayashizaki Y. Science 309:1559-1563(2005) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]. Strain: C57BL/6J. Tissue: Stomach and Tongue.
[2]	"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)." The MGC Project Team Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]. Tissue: Mammary gland.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AK008863 mRNA. No translation available. AK008896 mRNA. Translation: BAB25959.1. AK009005 mRNA. Translation: BAB26019.1. AK009809 mRNA. Translation: BAB26516.1. BC028496 mRNA. Translation: AAH28496.1.
IPI	IPI00132420.
RefSeq	NP_079816.1. NM_025540.2.
UniGene	Mm.29132.
3D structure databases
ProteinModelPortal	Q9CQD6.
SMR	Q9CQD6. Positions 1-31.
ModBase	Search...
Protein-protein interaction databases
STRING	10090.ENSMUSP00000036950.
PTM databases
PhosphoSite	Q9CQD6.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
Ensembl	ENSMUST00000048485; ENSMUSP00000036950; ENSMUSG00000042045.
GeneID	66402.
KEGG	mmu:66402.
UCSC	uc009pmp.1. mouse.
Organism-specific databases
CTD	6588.
MGI	MGI:1913652. Sln.
Phylogenomic databases
eggNOG	NOG140204.
GeneTree	ENSGT00530000064724.
HOGENOM	HOG000142457.
HOVERGEN	HBG079165.
InParanoid	Q9CQD6.
OrthoDB	EOG4XH01W.
Gene expression databases
Bgee	Q9CQD6.
CleanEx	MM_SLN.
Genevestigator	Q9CQD6.
GermOnline	ENSMUSG00000042045. Mus musculus.
Family and domain databases
InterPro	IPR008028. Sarcolipin. [Graphical view]
Pfam	PF05366. Sarcolipin. 1 hit. [Graphical view]
ProtoNet	Search...
Other
ChiTaRS	SLN. mouse.
NextBio	321575.
SOURCE	Search...

Entry information

Entry name

SARCO_MOUSE

Accession

Primary (citable) accession number: Q9CQD6

Entry history

Integrated into UniProtKB/Swiss-Prot:	December 13, 2002
Last sequence update:	June 1, 2001
Last modified:	May 1, 2013
This is version 77 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Chordata Protein Annotation Program