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Protein

Tetraspanin-31

Gene

Tspan31

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

GO - Biological processi

Complete GO annotation...

Names & Taxonomyi

Protein namesi
Recommended name:
Tetraspanin-31
Short name:
Tspan-31
Alternative name(s):
Sarcoma-amplified sequence homolog
Gene namesi
Name:Tspan31
Synonyms:Sas
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 10

Organism-specific databases

MGIiMGI:1914375. Tspan31.

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Topological domaini1 – 12CytoplasmicSequence analysisAdd BLAST12
Transmembranei13 – 33HelicalSequence analysisAdd BLAST21
Topological domaini34 – 44ExtracellularSequence analysisAdd BLAST11
Transmembranei45 – 65HelicalSequence analysisAdd BLAST21
Topological domaini66 – 72CytoplasmicSequence analysis7
Transmembranei73 – 93HelicalSequence analysisAdd BLAST21
Topological domaini94 – 173ExtracellularSequence analysisAdd BLAST80
Transmembranei174 – 194HelicalSequence analysisAdd BLAST21
Topological domaini195 – 210CytoplasmicSequence analysisAdd BLAST16

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002192711 – 210Tetraspanin-31Add BLAST210

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Glycosylationi109N-linked (GlcNAc...)Sequence analysis1
Glycosylationi117N-linked (GlcNAc...)1 Publication1
Glycosylationi134N-linked (GlcNAc...)Sequence analysis1

Keywords - PTMi

Glycoprotein

Proteomic databases

EPDiQ9CQ88.
MaxQBiQ9CQ88.
PaxDbiQ9CQ88.
PeptideAtlasiQ9CQ88.
PRIDEiQ9CQ88.

PTM databases

iPTMnetiQ9CQ88.
PhosphoSitePlusiQ9CQ88.
SwissPalmiQ9CQ88.

Expressioni

Gene expression databases

BgeeiENSMUSG00000006736.
CleanExiMM_TSPAN31.
GenevisibleiQ9CQ88. MM.

Interactioni

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000057751.

Structurei

3D structure databases

ProteinModelPortaliQ9CQ88.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the tetraspanin (TM4SF) family.Curated

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiKOG3882. Eukaryota.
ENOG4111IRY. LUCA.
GeneTreeiENSGT00500000044851.
HOGENOMiHOG000005650.
HOVERGENiHBG009195.
InParanoidiQ9CQ88.
KOiK17356.
OMAiFVFQFGI.
OrthoDBiEOG091G0PBF.
PhylomeDBiQ9CQ88.
TreeFamiTF323367.

Family and domain databases

InterProiIPR000301. Tetraspanin.
IPR018499. Tetraspanin/Peripherin.
[Graphical view]
PfamiPF00335. Tetraspannin. 1 hit.
[Graphical view]
PIRSFiPIRSF002419. Tetraspanin. 1 hit.
PRINTSiPR00259. TMFOUR.

Sequencei

Sequence statusi: Complete.

Q9CQ88-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MVCGGFACSR NALCALNVVY MLVGFLLIGV AAWGKGLGVV SSIHIIGGVI
60 70 80 90 100
AVGVFLLLIA VAGLVGAANH HQVLLFFYMI ILGLVFIFQF GISCSCLAIN
110 120 130 140 150
RNTQADVINA SWSVLSNSTR HELERSFDCC GLFNLTTLRL QDDTSCSAVC
160 170 180 190 200
KTKSSTCQMC GERFLKHSDK ALKILGGVGL FFSFTEILGV WLAMRFRNQK
210
DPRANPSAFL
Length:210
Mass (Da):22,694
Last modified:June 1, 2001 - v1
Checksum:iB1CAD508BEBCC9FD
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK012457 mRNA. Translation: BAB28252.1.
AK013523 mRNA. Translation: BAB28897.1.
AK014183 mRNA. Translation: BAB29196.1.
AK075962 mRNA. Translation: BAC36084.1.
BC023306 mRNA. Translation: AAH23306.1.
CCDSiCCDS24227.1.
RefSeqiNP_080258.1. NM_025982.4.
UniGeneiMm.35650.

Genome annotation databases

EnsembliENSMUST00000060991; ENSMUSP00000057751; ENSMUSG00000006736.
GeneIDi67125.
KEGGimmu:67125.
UCSCiuc007hhw.1. mouse.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK012457 mRNA. Translation: BAB28252.1.
AK013523 mRNA. Translation: BAB28897.1.
AK014183 mRNA. Translation: BAB29196.1.
AK075962 mRNA. Translation: BAC36084.1.
BC023306 mRNA. Translation: AAH23306.1.
CCDSiCCDS24227.1.
RefSeqiNP_080258.1. NM_025982.4.
UniGeneiMm.35650.

3D structure databases

ProteinModelPortaliQ9CQ88.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000057751.

PTM databases

iPTMnetiQ9CQ88.
PhosphoSitePlusiQ9CQ88.
SwissPalmiQ9CQ88.

Proteomic databases

EPDiQ9CQ88.
MaxQBiQ9CQ88.
PaxDbiQ9CQ88.
PeptideAtlasiQ9CQ88.
PRIDEiQ9CQ88.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000060991; ENSMUSP00000057751; ENSMUSG00000006736.
GeneIDi67125.
KEGGimmu:67125.
UCSCiuc007hhw.1. mouse.

Organism-specific databases

CTDi6302.
MGIiMGI:1914375. Tspan31.

Phylogenomic databases

eggNOGiKOG3882. Eukaryota.
ENOG4111IRY. LUCA.
GeneTreeiENSGT00500000044851.
HOGENOMiHOG000005650.
HOVERGENiHBG009195.
InParanoidiQ9CQ88.
KOiK17356.
OMAiFVFQFGI.
OrthoDBiEOG091G0PBF.
PhylomeDBiQ9CQ88.
TreeFamiTF323367.

Miscellaneous databases

PROiQ9CQ88.
SOURCEiSearch...

Gene expression databases

BgeeiENSMUSG00000006736.
CleanExiMM_TSPAN31.
GenevisibleiQ9CQ88. MM.

Family and domain databases

InterProiIPR000301. Tetraspanin.
IPR018499. Tetraspanin/Peripherin.
[Graphical view]
PfamiPF00335. Tetraspannin. 1 hit.
[Graphical view]
PIRSFiPIRSF002419. Tetraspanin. 1 hit.
PRINTSiPR00259. TMFOUR.
ProtoNetiSearch...

Entry informationi

Entry nameiTSN31_MOUSE
AccessioniPrimary (citable) accession number: Q9CQ88
Secondary accession number(s): Q9CUY7
Entry historyi
Integrated into UniProtKB/Swiss-Prot: April 26, 2005
Last sequence update: June 1, 2001
Last modified: November 2, 2016
This is version 104 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.